Mus caroli (Ryukyu mouse): 110296267 Help Entry 110296267         CDS       T05910                                  Gene name Hk2 Definition (RefSeq) hexokinase-2   KO K00844   hexokinase [EC:2.7.1.1] Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal00010   Glycolysis / Gluconeogenesis mcal00051   Fructose and mannose metabolism mcal00052   Galactose metabolism mcal00500   Starch and sucrose metabolism mcal00520   Amino sugar and nucleotide sugar metabolism mcal00524   Neomycin, kanamycin and gentamicin biosynthesis mcal01100   Metabolic pathways mcal01200   Carbon metabolism mcal04066   HIF-1 signaling pathway mcal04910   Insulin signaling pathway mcal04930   Type II diabetes mellitus mcal04973   Carbohydrate digestion and absorption mcal05230   Central carbon metabolism in cancer Module mcal_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mcal_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose mcal_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:mcal00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     110296267 (Hk2)    00051 Fructose and mannose metabolism     110296267 (Hk2)    00052 Galactose metabolism     110296267 (Hk2)    00500 Starch and sucrose metabolism     110296267 (Hk2)    00520 Amino sugar and nucleotide sugar metabolism     110296267 (Hk2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     110296267 (Hk2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     110296267 (Hk2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     110296267 (Hk2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     110296267 (Hk2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     110296267 (Hk2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     110296267 (Hk2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcal04131]     110296267 (Hk2) Enzymes [BR:mcal01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      110296267 (Hk2) Membrane trafficking [BR:mcal04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     110296267 (Hk2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  110296267 NCBI-ProteinID:  XP_021020535 Ensembl:  MGP_CAROLIEiJ_G0028531 UniProt:  A0A6P5PXC2 LinkDB All DBs Position 6 AA seq 917 aa AA seqDB search MIASHMIACLFTELNQNQVQKVDQYLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAA VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMR GSGTQLFDHIAECLANFMDKLQIKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV EGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGTLNDIRTEFDREIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKAELLFQGKLSPELLTTGSFETKDVSDIEDDKDGIQKAYQILVRLG LSPLQEDCVATHRICQIVSTRSASLCAATLAAVLWRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLS HEQLLEVKRRMKVEMEQGLSKETHEAAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDGEEGRMCVNMEWGAFGDNGCLDD LRTVFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILRHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDNLKVTVGVDGTLYKLHPHFAKVMHETVRDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcgcatatgatcgcctgcttattcacggagctcaaccaaaaccaagtgcag aaggttgaccagtatctctaccacatgcgtctctcagatgagacccttctggagatttct aggcggttccggaaggagatggagaaggggctaggagctactacgcaccctacagcagct gtgaagatgctgcccacctttgtgaggtcaactccagatgggacagaacatggcgagttc ctggctctggaccttggaggaaccaactttcgtgtgctccgagtaagggtgacagacaat ggtctccagagggtggagatggagaaccagatctacgccattcccgaggacatcatgcgg ggcagtggaacccagctgtttgaccacattgccgaatgcctggccaacttcatggacaag ctacagatcaaagagaagaagctcccgctgggcttcaccttctcgttcccctgccaccag acgaaactggatgagagtttcttggtctcatggactaaggggttcaagtccagtggtgtg gaaggcagagatgtggtggatctgatccggaaggccatccagcgcagaggggactttgac attgacattgtggctgtggtgaatgacacggttgggaccatgatgacgtgtggttatgat gatcagaactgcgagattggtctcattgtgggtactggcagtaatgcctgctacatggag gagatgcgtcacattgacatggtggagggcgacgagggacggatgtgcatcaacatggag tggggggcctttggggacgacggtacactcaatgacatccgaactgagtttgaccgagag atcgacatgggctcactgaaccccgggaagcagctgtttgagaagatgatcagcgggatg tacatgggggagttggtcaggctcatcctggtgaagatggccaaggctgagctgctgttc caagggaaactcagcccagagctccttaccactggctccttcgagaccaaagatgtctcg gatattgaagacgataaggacggaatccagaaggcctaccagatcctggtgcgcctgggt ctgagcccgctgcaggaggactgtgtggccacgcaccgaatctgccagattgtgtccacg cgctcggccagtctgtgtgcagccaccctggccgcagtgctgtggcggatcaaagagaac aagggcgaggagcgactccgctccaccatcggcgtggatggctctgtctacaagaaacat ccccattttgccaagcgtctccataaggcagtgaggaggctggtgcccgattgtgatgtc cgcttcctccgctctgaggatggcagcggcaagggggcggctatggtgacggcggtggct taccgtctggctgaccaacaccgggcccgccagaagaccctggagtctctgaagctgagc catgaacagctgctggaggttaagagaaggatgaaggtggaaatggagcagggtctgagc aaggagacgcacgaggccgcccctgtgaagatgctgcccacttatgtgtgtgccactcca gacggtacagagaaaggagacttcctggccttggatcttggaggaacaaacttccgggtc ctgctggtgcgcgtgcgtaatggcaagcgaaggggcgtagagatgcataacaagatctac tccatcccgcaggaggtcatgcatggcactggagaagagcttttcgaccacattgtccag tgcatcgcggacttccttgaatacatgggcatgaagggcgtgtccctacctttgggtttc accttctccttcccttgccagcagaacagcctggaccagagcatcctcctcaagtggaca aagggattcaaggcatctggctgcgagggcgaggatgtggtcaccttgctgaaggaagcc attcaccggcgagaggagttcgacctggatgtggtggccgtggtgaatgacacagttggg actatgatgacttgtggctatgaagaccctcactgtgaagttggcctcattgttggcact ggaagcaatgcctgctacatggaggagatgcgtaatgtggagttggtggacggagaggag ggacggatgtgtgtcaacatggagtggggagcgttcggggacaacggctgcctggatgac ctgcgcacagtgtttgatgtcgctgtggacgagctctctctcaaccctggcaaacagagg tttgagaagatgatcagcggcatgtacttgggcgagattgtgcgcaacatcctcatcgat ttcacaaagcgggggctgctcttccggggccgcatctcagagcgcctcaagacaagggga atctttgaaactaagttcctgtctcagatcgagagtgactgcctggccctgctacaggtc cgagccatcctgcgccacctagggctggagagcacgtgtgacgacagcatcattgtgaag gaggtgtgcactgtggtcgcccggcgtgcggcccagctctgtggcgcaggcatggctgcc gtggtggacaagataagagagaaccgcggactggacaatctcaaagtgacggtgggcgtg gacgggacactgtacaagcttcatcctcactttgccaaagtcatgcatgagacggtgaga gatctggctccgaaatgtgacgtgtccttcctggaatccgaggatggcagtgggaaggga gcagctctcatcactgctgtggcctgccgcatccgggaggccgggcagagatag

Mus caroli (Ryukyu mouse): 110302692 Help Entry 110302692         CDS       T05910                                  Gene name Hk1 Definition (RefSeq) hexokinase-1   KO K00844   hexokinase [EC:2.7.1.1] Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal00010   Glycolysis / Gluconeogenesis mcal00051   Fructose and mannose metabolism mcal00052   Galactose metabolism mcal00500   Starch and sucrose metabolism mcal00520   Amino sugar and nucleotide sugar metabolism mcal00524   Neomycin, kanamycin and gentamicin biosynthesis mcal01100   Metabolic pathways mcal01200   Carbon metabolism mcal04066   HIF-1 signaling pathway mcal04910   Insulin signaling pathway mcal04930   Type II diabetes mellitus mcal04973   Carbohydrate digestion and absorption mcal05230   Central carbon metabolism in cancer Module mcal_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mcal_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose mcal_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:mcal00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     110302692 (Hk1)    00051 Fructose and mannose metabolism     110302692 (Hk1)    00052 Galactose metabolism     110302692 (Hk1)    00500 Starch and sucrose metabolism     110302692 (Hk1)    00520 Amino sugar and nucleotide sugar metabolism     110302692 (Hk1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     110302692 (Hk1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     110302692 (Hk1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     110302692 (Hk1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     110302692 (Hk1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     110302692 (Hk1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     110302692 (Hk1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcal04131]     110302692 (Hk1) Enzymes [BR:mcal01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      110302692 (Hk1) Membrane trafficking [BR:mcal04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     110302692 (Hk1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  110302692 NCBI-ProteinID:  XP_021029133 Ensembl:  MGP_CAROLIEiJ_G0015381 LinkDB All DBs Position 10 AA seq 924 aa AA seqDB search MGWGAPLLSRMLHGPEQAGEASPVPERQSGSENPASEDRRPLEKQRSHHLYTMGQNCQKG QAVDVEPKIRPPLTEEKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKML PTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKSQNVSMESEVYDTPENIVHGSGS QLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGAD VVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRH IDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGE LVRLILVKMAKESLLFEGRITPELLTRGKFTTSDVAAIETGSTLSPGRRWYQAYMRRTQD THRDKEGVQNAKEILTRLGVEPSHDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNK GTPRLRTTVGVDGSLYKMHPQIQKEEKRVLPLSSVTRTIGFFSVFFLVTEHGDFLALDLG GTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVSCISDFLDYMGIKGP RMPLGFTFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLRDAVKRREEFDLDVVAV VNDTVGTMMTCAYEEPTCEIGLIVGTGSNACYMEEMKNVEMVEGNQGQMCINMEWGAFGD NGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISE PLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLC GAGMAAVVEKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCTVSFLLSE DGSGKGAALITAVGVRLRGDPTNA NT seq 2775 nt NT seq  +upstreamnt  +downstreamnt atgggatggggagcaccacttctctctaggatgctgcatggtccagaacaggctggggaa gctagccctgtgccagaaaggcagtcaggatcagaaaaccccgcttctgaggacagaaga cccttggaaaaacagcgtagccatcacctctacactatgggacagaactgccagaaagga caggctgtagatgttgaaccaaaaatacgaccccctctcacagaggaaaagattgataag tatctgtatgccatgcggctctctgatgaaattctgatagatatcctgacacgcttcaag aaggagatgaagaatggcctctcccgggactataacccaacagcctccgtcaagatgctg ccgacctttgtccggtccattccggatggctcagaaaagggggatttcattgcactggat ctcggcgggtcttcctttcgaatcctgcgggtgcaggtgaaccacgagaagagtcagaac gtcagcatggagtctgaggtctacgacaccccagagaacatcgtgcacggcagtggaagc cagctttttgatcacgtcgctgaatgcctcggagacttcatggagaaaaggaagatcaag gacaagaaattacccgtgggattcacgttttccttcccgtgccgacaatccaaaatagac gaggctgtactgatcacgtggacaaagcggttcaaagccagtggcgtggaaggggcggat gtggtcaagctgctgaataaagccattaagaagcgaggggactatgatgctaacattgta gctgtggtgaatgacacggtggggaccatgatgacctgcggctacgatgaccaacagtgt gaagtcggcctgatcattggcacaggcaccaatgcttgctacatggaggaactgcgacac atcgacctggtggaaggcgatgaggggaggatgtgtattaacacggaatggggagccttt ggggacgatgggtccctggaagacatccgaactgagtttgacagagagttagaccgggga tccctcaaccctgggaaacagctgttcgagaagatggtgagcggcatgtacatgggagag ctggtccggctgatcctggtgaagatggccaaggaaagtctcttatttgaagggcgcatt actccagagctgctcacgaggggcaagttcaccactagcgacgtagccgccattgaaacg ggatcgacactctcccctggccgcaggtggtaccaggcatatatgaggcgcacacaagac acccatagggataaggaaggcgttcaaaatgccaaggaaatcttgacccgcctgggagtg gagccatctcacgatgactgtgtatcggtccagcacgtatgcacaatcgtgtccttccga tcagccaacctggtggctgccacgctcggtgccatcttgaaccgcctgcgggacaataag ggcacgcccaggctgcggaccacagttggcgtagacggttctctctacaagatgcaccca caaatccaaaaagaagagaagcgggttcttccattgtcttcagtgacaagaaccataggc tttttctctgtgttcttccttgtgacagagcatggtgacttcctggccttggatctcgga ggaacgaatttccgagtcctactggtaaagatccgtagtgggaaaaagagaacagtggag atgcacaacaagatctactccattcccctggaaatcatgcagggcaccggggatgagctg tttgaccacattgtctcctgcatctccgacttcctggactacatggggatcaaaggcccc cggatgcctctgggcttcaccttctcgtttccctgcaagcagaccagcctagattgcgga atcttgatcacgtggacaaagggattcaaagccaccgactgtgtgggtcacgatgtagcc actttactgagggatgctgtaaaaaggagagaggaatttgacctggatgtggtggctgtg gtcaacgacactgtgggcaccatgatgacttgtgcttatgaagaacccacttgtgagatt ggactcatcgtggggactggcagcaatgcctgctacatggaggagatgaagaacgtggag atggtagaggggaaccagggccagatgtgcatcaatatggagtggggtgcctttggtgac aatggctgtctggacgacatcagaacagacttcgacaaagtggtggacgaatattctcta aacagtgggaaacaaaggtttgagaagatgatcagtggaatgtacctgggtgagatcgtc cgtaacatcctgattgacttcaccaagaaaggcttcctcttccggggacagatctctgag ccactcaagacccgaggcatcttcgagaccaagtttctctctcagatcgagagtgaccga ttagcgctgctccaggtgcgggccatccttcagcagctgggtctgaacagcacgtgcgac gacagtatcctggtcaagaccgtgtgtggggtggtgtccaagcgggcggcccagctgtgt ggtgccggcatggccgccgtggtggaaaagatccgagagaacagaggcctagaccacctg aatgtaactgtgggcgtggacgggacgctctacaaactccatccacatttctccagaatc atgcaccaaacagtgaaggaactgtcaccaaagtgtaccgtgtccttccttctgtctgaa gacggcagcggcaagggggctgcccttatcacagctgtgggcgtgcggctcagaggagac cctacgaacgcctaa

Mus caroli (Ryukyu mouse): 110303354 Help Entry 110303354         CDS       T05910                                  Gene name Hkdc1 Definition (RefSeq) putative hexokinase HKDC1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal00010   Glycolysis / Gluconeogenesis mcal00051   Fructose and mannose metabolism mcal00052   Galactose metabolism mcal00500   Starch and sucrose metabolism mcal00520   Amino sugar and nucleotide sugar metabolism mcal00524   Neomycin, kanamycin and gentamicin biosynthesis mcal01100   Metabolic pathways mcal01200   Carbon metabolism mcal04066   HIF-1 signaling pathway mcal04910   Insulin signaling pathway mcal04930   Type II diabetes mellitus mcal04973   Carbohydrate digestion and absorption mcal05230   Central carbon metabolism in cancer Module mcal_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mcal_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose mcal_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:mcal00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     110303354 (Hkdc1)    00051 Fructose and mannose metabolism     110303354 (Hkdc1)    00052 Galactose metabolism     110303354 (Hkdc1)    00500 Starch and sucrose metabolism     110303354 (Hkdc1)    00520 Amino sugar and nucleotide sugar metabolism     110303354 (Hkdc1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     110303354 (Hkdc1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     110303354 (Hkdc1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     110303354 (Hkdc1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     110303354 (Hkdc1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     110303354 (Hkdc1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     110303354 (Hkdc1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcal04131]     110303354 (Hkdc1) Enzymes [BR:mcal01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      110303354 (Hkdc1) Membrane trafficking [BR:mcal04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     110303354 (Hkdc1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 VPS13_mid_rpt CSD Motif Other DBs NCBI-GeneID:  110303354 NCBI-ProteinID:  XP_021030110 Ensembl:  MGP_CAROLIEiJ_G0015382 UniProt:  A0A6P5QJM0 LinkDB All DBs Position 10 AA seq 915 aa AA seqDB search MFAVHLVAFYFTKLKEDQIKKVDRFLYHMRLSDETLVDIMARFQAEMEKGLGKDTNPTAS VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSQEGQQNVQMESQFYPMPNEITR GNGTELFDYVADCLADFMKTKDLTHKKLPLGFTFSFPCRQNKLEEGVLLSWTKKFKARGV QDTDVVNRLATAMKKHKDLDVDILALVNDTVGTMMTCAYDDPNCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPRKQLFEKMISGL YMGELVRLILLKMAKVGLLFGGAKSSALHTKGKIETQHVAAMEMSKEGLANTREILVDLG LEPSESDCIAVQHVCTIVSFRSANLCAAALATILTRLRENKKLARLRTTVGMDGTLYKTH PQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT REQLLGVRDKMRAELEYGLKKKTHSLATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRV LLVKIRRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFTFS FPCRQTCIDKGTLVGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGTMM TCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVDGDEGRMCVNTEWGGFGDNGCIDDIRT QYDKEVDDGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRGQISERLRTRGIFE TKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQMCGAGMAAIVE KRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKELAPQCDVTFMLSEDGSGKGAAL ITAVAKRLQQPRKDI NT seq 2748 nt NT seq  +upstreamnt  +downstreamnt atgtttgcagtacacttggtggcgttttacttcaccaagctgaaggaggaccagatcaag aaggtggacaggttcctgtatcacatgcggctctcggatgagaccctggtggacatcatg gcccgcttccaggccgagatggagaaaggcttggggaaggacaccaaccccactgcctct gtgaagatgctgcccacgtttgtcagggccattccagatggctcagaaaacggggaattc ctttccctggatctcggaggatccaagtttcgggtcttgaaggtgcaagtctcccaagag ggccagcaaaatgttcagatggagagccagttctacccaatgcccaatgaaatcacccgt gggaatggcacggagctctttgactacgtagccgactgcctggcagatttcatgaagacc aaagatctgacgcataagaagctgcctctgggcttcaccttttcttttccctgcagacag aataagttggaggagggtgttctgctttcgtggaccaagaagttcaaggcccggggagtt caggacacagacgtggtgaaccgcctggccactgccatgaagaagcacaaggacctggat gtggacatcctggctttggttaacgacactgtggggaccatgatgacttgtgcttatgat gatcccaactgtgaagtcggcgttatcatcggaacaggcaccaacgcgtgttacatggag gacatgagcaacatcgacctcgtggaaggggacgagggaaggatgtgtatcaacacggag tggggggccttcggggacgatggggctttggaggacatccgtaccgagtttgacagagag ctggacctgggctcgctcaaccccaggaagcagctgttcgagaagatgatcagcgggctg tacatgggggagctggtcaggcttatcttgctgaagatggccaaagttggtctcctgttt gggggtgcaaaatcctccgctctccatacaaagggcaagatcgaaacacagcacgtggct gccatggagatgagtaaagaaggcctggccaacacgcgagagatcctggtggatttgggc ctggagccctctgagtcagactgcattgctgtccagcatgtgtgcaccatcgtctctttt cgctcagccaatctctgcgcggcggcactggcaaccatcctgacgcgcctccgagagaac aagaagctggcccggctccgcaccacagtgggcatggatggaactctctacaagacacac cctcagtaccccaaacgcctacacaaggtggtgaggagactggtcccaaactgtgatgtc cgcttcctcctgtcagagagcggaagcaccaagggggctgccatggtgaccgcagtggcc tctcgggtacaggcccagcgcaagcagatcgacaaggtgctagctttgttccagttgacc cgagagcaactcctgggtgtgcgggacaagatgagggctgaactagagtacgggctgaag aaaaagacccactctctggctaccgtgaagatgcttcccacctatgtctacgggatgccg gatggcacagagaaaggaaagttccttgccctggatttggggggaaccaacttccgagtc ctcctggtgaagatcaggcggaggtctgtgcgcatgtacaacaagatcttcgccatccct ctggagatcatgcagggcactggggaggaactctttgaccacatcgtacagtgcatcgct gacttcctggactacatgggcctcaagggcgcccagctgcctttgggcttcaccttctcc ttcccctgcagacagacatgcatcgacaaggggactctagtagggtggaccaaaggcttc aaggccaccgactgtgaaggggaggatgtggtggacatgctcagagaagccatcaagagg agaaatgagtttgacctggacattgttgcaatcgtgaacgacacggtggggaccatgatg acctgtggctatgaagatcccaggtgtgagattggcttgattgcagggacaggaagcaac gtgtgctacatggaggaaatgaggaatatcgagctggtggacggggacgaaggccggatg tgcgttaacacagagtggggcgggtttggtgacaatggctgcattgatgacatccgcacc cagtacgacaaggaggtggatgacggctccctcaacgccggcaagcagagatacgagaaa atgaccagtgggatgtacctgggggagattgtgaggcggatcttgatcgacctcacccgg caggggctcctcttccgagggcagatttcagagcgactccggaccaggggcatctttgaa accaaattcctgtcccagattgaaagtgaccggctggccctcctgcaggtcaggaggatc ctgcagcagctgggcctggacagcacatgcgaagacagtattgtggtgaaggaggtgtgt ggggctgtgtctcggagggccgcccagatgtgtggcgccggcatggctgccatcgtggag aagaggagagaagaccagggcctccagcacttcaaggtcaccgtgggcgtggatggcaca ctgtacaagctgcacccacacttctcccggatactgcaggagacggtgaaagagctggcc cctcagtgtgatgtgacatttatgttgtcagaagacggcagcgggaagggagcagctctg atcacagctgtagccaagaggttacagcagccacggaaggacatctag

Mus caroli (Ryukyu mouse): 110305090 Help Entry 110305090         CDS       T05910                                  Gene name Gck Definition (RefSeq) glucokinase isoform X1   KO K12407   glucokinase [EC:2.7.1.2] Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal00010   Glycolysis / Gluconeogenesis mcal00052   Galactose metabolism mcal00500   Starch and sucrose metabolism mcal00520   Amino sugar and nucleotide sugar metabolism mcal00524   Neomycin, kanamycin and gentamicin biosynthesis mcal01100   Metabolic pathways mcal01200   Carbon metabolism mcal04910   Insulin signaling pathway mcal04911   Insulin secretion mcal04917   Prolactin signaling pathway mcal04922   Glucagon signaling pathway mcal04930   Type II diabetes mellitus mcal04950   Maturity onset diabetes of the young mcal05230   Central carbon metabolism in cancer Module mcal_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mcal_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose mcal_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:mcal00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     110305090 (Gck)    00052 Galactose metabolism     110305090 (Gck)    00500 Starch and sucrose metabolism     110305090 (Gck)    00520 Amino sugar and nucleotide sugar metabolism     110305090 (Gck)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     110305090 (Gck)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     110305090 (Gck)    04910 Insulin signaling pathway     110305090 (Gck)    04922 Glucagon signaling pathway     110305090 (Gck)    04917 Prolactin signaling pathway     110305090 (Gck)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     110305090 (Gck)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     110305090 (Gck)    04950 Maturity onset diabetes of the young     110305090 (Gck) Enzymes [BR:mcal01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      110305090 (Gck) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  110305090 NCBI-ProteinID:  XP_021032531 Ensembl:  MGP_CAROLIEiJ_G0016063 UniProt:  A0A6P5QNC4 LinkDB All DBs Position 11 AA seq 465 aa AA seqDB search MAVDTTRRGAQSLTLVEQILAEFQLQEEDLKKVMSRMQKEMDRGLRLETHQEASVKMLPT YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTAE MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQN VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRMVDESSVNPGQQLYEKIIGGKYMGE LVRLVLLKLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRRQIRNILSTLGLRPS VADCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK ERFHASVRRLTPNCEITFIESEEGSGRGAALVSAVACKKACMLGQ NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atggctgtggatactacaaggaggggagcccagtcgttgactctggtagagcagatcctg gcagagttccagctgcaggaggaagacctgaagaaggtgatgagccggatgcagaaggag atggaccgtggcctgaggctggagacccatcaggaggccagtgtaaagatgttgcccacc tacgtgcgttccaccccagaaggctcagaagttggagactttctctccttagacctggga ggaaccaacttcagggtgatgctggtgaaggtgggggagggggaggcaggacagtggagc gtgaagacgaaacaccagatgtattccatccctgaggacgccatgacgggcactgcggag atgctctttgactacatctctgagtgcatctctgacttcctggacaagcatcagatgaaa cacaagaaactacccctgggcttcaccttctccttccctgtaaggcacgaagacatagac aagggcatcctgctcaactggaccaagggcttcaaggcctccggagcagaagggaacaac atcgtgggacttctccgagatgctatcaagaggagaggggactttgagatggatgtggtg gcaatggtaaatgacacggtggccacaatgatctcctgctactatgaagaccgccaatgt gaggtcggcatgattgtgggcactggctgcaacgcctgctacatggaagagatgcagaac gtggagctggtggaaggcgatgaggggcgcatgtgtgtcaacacagagtggggcgccttc ggggactccggtgagctggacgagttcctgctggagtacgaccggatggtggatgagagc tcagtgaaccccggtcagcagctgtacgaaaagatcattggtggaaagtacatgggcgag ctggtacgacttgtgctgctgaagctggtggacgagaatcttctgttccacggagaggcc tcagaacagctgcgcacacgtggcgcttttgagacccgttttgtgtcgcaggtggagagc gactctggggaccgaaggcagattcgtaacatcctgagcactctggggcttcgaccctct gtcgccgactgcgacattgtgcgccgtgcctgtgaaagcgtgtccactcgcgccgcccac atgtgctcagcaggactagcgggggtcataaatcgcatgcgcgaaagccgcagtgaggac gtgatgcgcatcacggtgggcgtggatggctccgtgtacaagctgcacccgagcttcaag gagcggtttcacgccagtgtgcgcaggctgacacccaactgcgaaatcaccttcatcgaa tcagaggagggcagcggcaggggagccgcactggtctctgcagtggcctgcaagaaggct tgcatgctgggccagtga

Mus caroli (Ryukyu mouse): 110307543 Help Entry 110307543         CDS       T05910                                  Gene name Hk3 Definition (RefSeq) hexokinase-3 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal00010   Glycolysis / Gluconeogenesis mcal00051   Fructose and mannose metabolism mcal00052   Galactose metabolism mcal00500   Starch and sucrose metabolism mcal00520   Amino sugar and nucleotide sugar metabolism mcal00524   Neomycin, kanamycin and gentamicin biosynthesis mcal01100   Metabolic pathways mcal01200   Carbon metabolism mcal04066   HIF-1 signaling pathway mcal04910   Insulin signaling pathway mcal04930   Type II diabetes mellitus mcal04973   Carbohydrate digestion and absorption mcal05230   Central carbon metabolism in cancer Module mcal_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mcal_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose mcal_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:mcal00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     110307543 (Hk3)    00051 Fructose and mannose metabolism     110307543 (Hk3)    00052 Galactose metabolism     110307543 (Hk3)    00500 Starch and sucrose metabolism     110307543 (Hk3)    00520 Amino sugar and nucleotide sugar metabolism     110307543 (Hk3)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     110307543 (Hk3)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     110307543 (Hk3)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     110307543 (Hk3)   09154 Digestive system    04973 Carbohydrate digestion and absorption     110307543 (Hk3)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     110307543 (Hk3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     110307543 (Hk3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcal04131]     110307543 (Hk3) Enzymes [BR:mcal01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      110307543 (Hk3) Membrane trafficking [BR:mcal04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     110307543 (Hk3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Cyanophycin_syn Motif Other DBs NCBI-GeneID:  110307543 NCBI-ProteinID:  XP_021035436 Ensembl:  MGP_CAROLIEiJ_G0018549 UniProt:  A0A6P5R0Z6 LinkDB All DBs Position 13 AA seq 922 aa AA seqDB search MATIGPSGLHPGERASICPHEGVPRPSGSLELECLQQFKVTMTQLQQIQASLLCSMEQAL KGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKECRVEPRS REFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDRSTLI SWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDVVAMVNDTVGTMMGCELGTRPCEVGLI VDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFHDEDALGPVLTTFDSALDRESLTPG AQRFEKMIGGLYLGELVRLVLVHLTQNGVLFDGCTSPALLSQGCILLDHVAEMEDTATGT ARVHTILQDLGLSPRASDAELVQCVCVAVCTRAAQLCAAALAAVLSRLQHSREQKTLQVA VATGGRVFERHPRFLQILEETVMLLAPNCDVSFIPSVDGGGRGVAMVTAVAARLAAHRRI LEETLAPFQLTLEQLTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALD LGGTNFRVLLVQVAEGSVQIINQVYSIPEFVAQGSGQKLFDHIVDCIVDFQKRQGLSGQS LPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIV NDTVGTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVSSVPGDSGLMCINMEWGAFGDD GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHVLLHLTNLGVLFRGQKTQR LQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLTLTSDDALMVLEVCQAVSRRAAQLCG AGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSATVRKLAPQCTVTFLQSED GSGKGAALVTAVACRLTQMAHV NT seq 2769 nt NT seq  +upstreamnt  +downstreamnt atggccaccattgggccttctggcctgcatcctggagagagagcctcaatctgcccacac gagggcgtgccaaggccctcaggtagcttagaactggaatgcttgcagcaattcaaggtg accatgacacagttgcagcagatccaagccagtctcctgtgctccatggagcaggcactg aagggacaggacagtcccgctccttctgtccggatgctgcccacatacgtgaggtccaca ccacatggcaccgagcaaggggatttcctggtgctggagctgggggccacaggagcatca ctacgtgtgttgtgggtaacactgacaggcaccaaagaatgccgtgtggagcccaggagc cgggagttcgtgattcctcaagaggtgatcctaggtgctggccagcagctctttgacttt gctgcccgctgcctctctgaattcctggatgcgtaccccgtggagaatcagggtctgaag cttgggttcaatttctcttttccttgtcaccagacaggcttggacaggagcaccctcatt tcctggacaaaaggttttaggtgcagtggcgtggaaggccaggatgtggtccagttgcta agagatgccattcagaggcaggggacctacaggattgatgtggtagccatggtgaatgac acggtgggcaccatgatgggctgtgagctgggcaccaggccgtgtgaagttgggctgatt gtagacaccggtaccaacgcgtgctacatggaggaggcgcggcacgtggccgctctggat gaggaccgcggccgcacctgtgtcagcatcgagtggggctccttccatgacgaagatgcc ctagggccagtactgaccaccttcgactctgccctggaccgcgagtccctgactcctggt gctcaaaggtttgagaagatgattggaggcctttacctgggtgagctggtgaggctggtt ctggtccacttgacccagaacggggtcctttttgatggctgcacctctcctgcgttgctg agtcaaggctgtatcctcctggaccacgtggctgagatggaggacaccgccactgggaca gcccgcgtccacaccatcctgcaggacttgggtctgagccctcgggcctcagatgctgaa ctggtgcaatgtgtatgcgtggctgtgtgcacacgggctgcccagctctgtgcggctgcc ctggctgcagtcctctcccgcctccagcacagcagggagcagaagacattgcaagtggct gtggccactggagggcgagtgtttgaacgacaccccaggttcctccaaatcctagaggag acggtaatgctcctggccccaaactgtgatgtctccttcatcccctctgtggatggtggt ggccggggtgtggcaatggtgacagctgtggctgcccgcctggctgctcacaggcgcatc ctggaagagaccctggcaccatttcagctgaccttggagcagctgacagtggtgcaggca caaatgcgggaagccatgatcagggggcttcaaggagaggcctcctccctccgcatgctg cccacttacgtccgagcgacgcccgacggcagcgagcgaggtgatttcctggccttggac ctagggggcaccaacttccgtgtcctgttggtacaagtggccgagggcagtgtgcagatc atcaaccaggtctactccattcctgagtttgtagcccagggctctggacagaagctcttt gaccatattgtggactgcatcgtggacttccagaagaggcagggccttagtggacagagc ctacccctgggtttcaccttctctttcccatgcaagcagcttggcctggaccagggcatc ctcctgaattggactaaggggttcaatgcatcaggctgtgagggccaggatgttgtgtat ctattacgggaagccattaggcgcagacaggcagtggagctgaatgtggttgccattgtc aatgacacggtggggaccatgatgtcctgtggctatgatgatccccgttgtgagatgggc ctcattgtcggaaccggcaccaacgcctgttacatggaagagctccgaaatgtgtcaagt gtgcctggggactcgggcctcatgtgcatcaacatggagtggggtgcctttggggatgat ggctcactgggcacactcagcacccgctttgacaccagtgtggaccaggcatccatcaat ccaggcaaacagaggtttgagaaaatgattagcggtatgtacctgggggagatcgtccgc catgtcctcctgcacttaaccaatctcggagttctcttccgaggccagaagactcaacgt cttcagaccagggacatctttaagaccaagttcctctctgagattgaaagtgacagcctg gccctgcgacaggtccgagccatcctggaggatctggggctgactctgacatctgatgac gccttgatggtcctggaagtgtgccaggctgtgtctcgcagggctgcccaactctgtggg gcaggtgtggctgccgtggtggaaaagatacgggagaaccggggcctgcaggagctgaca gtgtctgtgggagtagatgggacactctacaagctacatcctcacttctccaggctggtg tcggcaacagtcaggaagctagcccctcagtgcaccgtcacctttttgcagtcggaggat gggtctggcaaaggcgcagctttggttactgctgttgcttgtcgccttacccagatggcc cacgtctga

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