Mus caroli (Ryukyu mouse): 110296919
Help
Entry
110296919 CDS
T05910
Gene name
Raf1
Definition
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal01521
EGFR tyrosine kinase inhibitor resistance
mcal01522
Endocrine resistance
mcal04010
MAPK signaling pathway
mcal04012
ErbB signaling pathway
mcal04014
Ras signaling pathway
mcal04015
Rap1 signaling pathway
mcal04022
cGMP-PKG signaling pathway
mcal04024
cAMP signaling pathway
mcal04062
Chemokine signaling pathway
mcal04068
FoxO signaling pathway
mcal04071
Sphingolipid signaling pathway
mcal04072
Phospholipase D signaling pathway
mcal04140
Autophagy - animal
mcal04150
mTOR signaling pathway
mcal04151
PI3K-Akt signaling pathway
mcal04210
Apoptosis
mcal04218
Cellular senescence
mcal04270
Vascular smooth muscle contraction
mcal04360
Axon guidance
mcal04370
VEGF signaling pathway
mcal04371
Apelin signaling pathway
mcal04510
Focal adhesion
mcal04540
Gap junction
mcal04550
Signaling pathways regulating pluripotency of stem cells
mcal04613
Neutrophil extracellular trap formation
mcal04625
C-type lectin receptor signaling pathway
mcal04630
JAK-STAT signaling pathway
mcal04650
Natural killer cell mediated cytotoxicity
mcal04660
T cell receptor signaling pathway
mcal04662
B cell receptor signaling pathway
mcal04664
Fc epsilon RI signaling pathway
mcal04666
Fc gamma R-mediated phagocytosis
mcal04720
Long-term potentiation
mcal04722
Neurotrophin signaling pathway
mcal04726
Serotonergic synapse
mcal04730
Long-term depression
mcal04810
Regulation of actin cytoskeleton
mcal04910
Insulin signaling pathway
mcal04912
GnRH signaling pathway
mcal04914
Progesterone-mediated oocyte maturation
mcal04915
Estrogen signaling pathway
mcal04916
Melanogenesis
mcal04917
Prolactin signaling pathway
mcal04919
Thyroid hormone signaling pathway
mcal04921
Oxytocin signaling pathway
mcal04926
Relaxin signaling pathway
mcal04928
Parathyroid hormone synthesis, secretion and action
mcal04929
GnRH secretion
mcal04935
Growth hormone synthesis, secretion and action
mcal05010
Alzheimer disease
mcal05022
Pathways of neurodegeneration - multiple diseases
mcal05034
Alcoholism
mcal05132
Salmonella infection
mcal05152
Tuberculosis
mcal05160
Hepatitis C
mcal05161
Hepatitis B
mcal05163
Human cytomegalovirus infection
mcal05164
Influenza A
mcal05165
Human papillomavirus infection
mcal05167
Kaposi sarcoma-associated herpesvirus infection
mcal05170
Human immunodeficiency virus 1 infection
mcal05200
Pathways in cancer
mcal05205
Proteoglycans in cancer
mcal05206
MicroRNAs in cancer
mcal05210
Colorectal cancer
mcal05211
Renal cell carcinoma
mcal05212
Pancreatic cancer
mcal05213
Endometrial cancer
mcal05214
Glioma
mcal05215
Prostate cancer
mcal05218
Melanoma
mcal05219
Bladder cancer
mcal05220
Chronic myeloid leukemia
mcal05221
Acute myeloid leukemia
mcal05223
Non-small cell lung cancer
mcal05224
Breast cancer
mcal05225
Hepatocellular carcinoma
mcal05226
Gastric cancer
mcal05230
Central carbon metabolism in cancer
mcal05231
Choline metabolism in cancer
mcal05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110296919 (Raf1)
04012 ErbB signaling pathway
110296919 (Raf1)
04014 Ras signaling pathway
110296919 (Raf1)
04015 Rap1 signaling pathway
110296919 (Raf1)
04370 VEGF signaling pathway
110296919 (Raf1)
04371 Apelin signaling pathway
110296919 (Raf1)
04630 JAK-STAT signaling pathway
110296919 (Raf1)
04068 FoxO signaling pathway
110296919 (Raf1)
04072 Phospholipase D signaling pathway
110296919 (Raf1)
04071 Sphingolipid signaling pathway
110296919 (Raf1)
04024 cAMP signaling pathway
110296919 (Raf1)
04022 cGMP-PKG signaling pathway
110296919 (Raf1)
04151 PI3K-Akt signaling pathway
110296919 (Raf1)
04150 mTOR signaling pathway
110296919 (Raf1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110296919 (Raf1)
09143 Cell growth and death
04210 Apoptosis
110296919 (Raf1)
04218 Cellular senescence
110296919 (Raf1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110296919 (Raf1)
04540 Gap junction
110296919 (Raf1)
04550 Signaling pathways regulating pluripotency of stem cells
110296919 (Raf1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110296919 (Raf1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
110296919 (Raf1)
04625 C-type lectin receptor signaling pathway
110296919 (Raf1)
04650 Natural killer cell mediated cytotoxicity
110296919 (Raf1)
04660 T cell receptor signaling pathway
110296919 (Raf1)
04662 B cell receptor signaling pathway
110296919 (Raf1)
04664 Fc epsilon RI signaling pathway
110296919 (Raf1)
04666 Fc gamma R-mediated phagocytosis
110296919 (Raf1)
04062 Chemokine signaling pathway
110296919 (Raf1)
09152 Endocrine system
04910 Insulin signaling pathway
110296919 (Raf1)
04929 GnRH secretion
110296919 (Raf1)
04912 GnRH signaling pathway
110296919 (Raf1)
04915 Estrogen signaling pathway
110296919 (Raf1)
04914 Progesterone-mediated oocyte maturation
110296919 (Raf1)
04917 Prolactin signaling pathway
110296919 (Raf1)
04921 Oxytocin signaling pathway
110296919 (Raf1)
04926 Relaxin signaling pathway
110296919 (Raf1)
04935 Growth hormone synthesis, secretion and action
110296919 (Raf1)
04919 Thyroid hormone signaling pathway
110296919 (Raf1)
04928 Parathyroid hormone synthesis, secretion and action
110296919 (Raf1)
04916 Melanogenesis
110296919 (Raf1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
110296919 (Raf1)
09156 Nervous system
04726 Serotonergic synapse
110296919 (Raf1)
04720 Long-term potentiation
110296919 (Raf1)
04730 Long-term depression
110296919 (Raf1)
04722 Neurotrophin signaling pathway
110296919 (Raf1)
09158 Development and regeneration
04360 Axon guidance
110296919 (Raf1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110296919 (Raf1)
05206 MicroRNAs in cancer
110296919 (Raf1)
05205 Proteoglycans in cancer
110296919 (Raf1)
05230 Central carbon metabolism in cancer
110296919 (Raf1)
05231 Choline metabolism in cancer
110296919 (Raf1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110296919 (Raf1)
09162 Cancer: specific types
05210 Colorectal cancer
110296919 (Raf1)
05212 Pancreatic cancer
110296919 (Raf1)
05225 Hepatocellular carcinoma
110296919 (Raf1)
05226 Gastric cancer
110296919 (Raf1)
05214 Glioma
110296919 (Raf1)
05221 Acute myeloid leukemia
110296919 (Raf1)
05220 Chronic myeloid leukemia
110296919 (Raf1)
05218 Melanoma
110296919 (Raf1)
05211 Renal cell carcinoma
110296919 (Raf1)
05219 Bladder cancer
110296919 (Raf1)
05215 Prostate cancer
110296919 (Raf1)
05213 Endometrial cancer
110296919 (Raf1)
05224 Breast cancer
110296919 (Raf1)
05223 Non-small cell lung cancer
110296919 (Raf1)
09164 Neurodegenerative disease
05010 Alzheimer disease
110296919 (Raf1)
05022 Pathways of neurodegeneration - multiple diseases
110296919 (Raf1)
09165 Substance dependence
05034 Alcoholism
110296919 (Raf1)
09171 Infectious disease: bacterial
05132 Salmonella infection
110296919 (Raf1)
05152 Tuberculosis
110296919 (Raf1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
110296919 (Raf1)
05161 Hepatitis B
110296919 (Raf1)
05160 Hepatitis C
110296919 (Raf1)
05164 Influenza A
110296919 (Raf1)
05163 Human cytomegalovirus infection
110296919 (Raf1)
05167 Kaposi sarcoma-associated herpesvirus infection
110296919 (Raf1)
05165 Human papillomavirus infection
110296919 (Raf1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110296919 (Raf1)
01522 Endocrine resistance
110296919 (Raf1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcal01001
]
110296919 (Raf1)
Enzymes [BR:
mcal01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110296919 (Raf1)
Protein kinases [BR:
mcal01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
110296919 (Raf1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
110296919
NCBI-ProteinID:
XP_021021383
Ensembl:
MGP_CAROLIEiJ_G0028755
UniProt:
A0A6P5PZJ3
LinkDB
All DBs
Position
6
AA seq
648 aa
AA seq
DB search
MEHIQGAWKTISNGFGLKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDSSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTVGDSGVPAPPSFPMRRMRESVSRMPASSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLHVDSRMIEDAIRSHSESASPSALSSSPNNL
SPTGWSQPKTPVPAQRERAPGSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggagcttggaagacgatcagcaacggctttggactcaaagatgcg
gtgtttgatggctccagctgcatctcccctaccattgttcagcagtttggctatcagcgc
cgggcctcagatgatggcaaactcacggattcttctaagacaagcaatactatccgggtt
ttcttgccgaataagcaaaggactgtggtcaatgtgcggaatggaatgagcttgcatgac
tgccttatgaaagctctgaaggtgagaggcctgcagccagaatgctgtgcagtgttcaga
cttctccaggaacacaaaggtaagaaagcacgcttagattggaacaccgatgctgcctct
ctgattggagaagaactgcaagtggattttttggatcatgttccactcacaactcacaac
tttgctcggaaaacgttcctgaagcttgcattctgtgacatctgtcagaagttcctgcta
aatggatttcgatgtcagacttgtggctacaagtttcatgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacagctcttgctgtttccaaattccact
gttggtgacagtggagtcccagcaccaccttctttcccaatgcgccggatgcgagaatct
gtttcccggatgcctgctagttcccagcacagatactccacaccccacgccttcactttc
aacacctccagcccttcctcagaaggttccctgtcccagaggcagaggtcaacgtccact
cccaatgtccacatggtcagcaccaccctgcatgtggacagcaggatgattgaggatgca
attcgaagtcacagtgaatcagcctcaccttcagccctgtccagcagcccaaacaacctg
agtccaacaggctggtcacagcccaaaacccctgtgccagcacaaagagagcgggcacca
ggatctgggacccaggaaaaaaacaaaattaggcctcgtgggcagagagattcaagttat
tactgggaaatagaagccagtgaggtgatgctgtctactcggatcgggtcaggttccttt
ggcactgtgtacaagggcaagtggcatggagatgttgcagtaaagatcctaaaggtggtt
gacccaactccagagcaactccaggccttcaggaacgaggtggctgttttgcgcaaaaca
cggcatgttaacatcctgctgttcatggggtacatgacaaaggacaacctggcgattgtg
acccagtggtgtgagggcagcagtctctacaaacacctgcatgtccaggagaccaaattc
cagatgttccagctaattgacattgcccgacagacagctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggcctc
acggtgaaaattggagattttggtttggcaacagtgaagtcacgctggagtggttctcag
caggttgaacagcccactggctctgtgctgtggatggccccagaagtaatccggatgcag
gataacaacccgttcagcttccaatccgacgtctactcctatggcatcgtgctgtacgag
ctgatgactggggagcttccctacgcccacatcaacaaccgagaccagatcatcttcatg
gtaggccgtgggtatgcatccccagatctcagcaggctctacaagaactgccccaaggca
atgaagaggttggtggctgactgtgtgaagaaagtcaaagaagagagacctttgtttccc
cagatcctgtcttccatagagctgcttcagcactctctgccgaaaatcaacaggagcgcc
tctgagccttccctgcatcgggcagctcacactgaggacatcaatgcttgcacgctgact
acatccccaaggctaccagtcttctag
DBGET
integrated database retrieval system
