Mus caroli (Ryukyu mouse): 110297825
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Entry
110297825 CDS
T05910
Gene name
Igf1r
Definition
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal01521
EGFR tyrosine kinase inhibitor resistance
mcal01522
Endocrine resistance
mcal04010
MAPK signaling pathway
mcal04014
Ras signaling pathway
mcal04015
Rap1 signaling pathway
mcal04066
HIF-1 signaling pathway
mcal04068
FoxO signaling pathway
mcal04114
Oocyte meiosis
mcal04140
Autophagy - animal
mcal04144
Endocytosis
mcal04150
mTOR signaling pathway
mcal04151
PI3K-Akt signaling pathway
mcal04152
AMPK signaling pathway
mcal04211
Longevity regulating pathway
mcal04213
Longevity regulating pathway - multiple species
mcal04510
Focal adhesion
mcal04520
Adherens junction
mcal04550
Signaling pathways regulating pluripotency of stem cells
mcal04730
Long-term depression
mcal04913
Ovarian steroidogenesis
mcal04914
Progesterone-mediated oocyte maturation
mcal05200
Pathways in cancer
mcal05202
Transcriptional misregulation in cancer
mcal05205
Proteoglycans in cancer
mcal05214
Glioma
mcal05215
Prostate cancer
mcal05218
Melanoma
mcal05224
Breast cancer
mcal05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110297825 (Igf1r)
04014 Ras signaling pathway
110297825 (Igf1r)
04015 Rap1 signaling pathway
110297825 (Igf1r)
04066 HIF-1 signaling pathway
110297825 (Igf1r)
04068 FoxO signaling pathway
110297825 (Igf1r)
04151 PI3K-Akt signaling pathway
110297825 (Igf1r)
04152 AMPK signaling pathway
110297825 (Igf1r)
04150 mTOR signaling pathway
110297825 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110297825 (Igf1r)
04140 Autophagy - animal
110297825 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
110297825 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110297825 (Igf1r)
04520 Adherens junction
110297825 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
110297825 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
110297825 (Igf1r)
04914 Progesterone-mediated oocyte maturation
110297825 (Igf1r)
09156 Nervous system
04730 Long-term depression
110297825 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
110297825 (Igf1r)
04213 Longevity regulating pathway - multiple species
110297825 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110297825 (Igf1r)
05202 Transcriptional misregulation in cancer
110297825 (Igf1r)
05205 Proteoglycans in cancer
110297825 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
110297825 (Igf1r)
05214 Glioma
110297825 (Igf1r)
05218 Melanoma
110297825 (Igf1r)
05215 Prostate cancer
110297825 (Igf1r)
05224 Breast cancer
110297825 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110297825 (Igf1r)
01522 Endocrine resistance
110297825 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcal01001
]
110297825 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mcal04090
]
110297825 (Igf1r)
Enzymes [BR:
mcal01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110297825 (Igf1r)
Protein kinases [BR:
mcal01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
110297825 (Igf1r)
CD molecules [BR:
mcal04090
]
Proteins
110297825 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Insulin_TMD
B2
DUF4476
Motif
Other DBs
NCBI-GeneID:
110297825
NCBI-ProteinID:
XP_021022505
Ensembl:
MGP_CAROLIEiJ_G0029853
UniProt:
A0A6P5Q006
LinkDB
All DBs
Position
7
AA seq
1373 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGD
LCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCH
TPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHD
DECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGN
LLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYS
FYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERRRRDVMQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELEMELEMEPENMESVPLDPSASSASL
PLPERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC
NT seq
4122 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgtttctctcc
gccgcgctctctctctggccgacgagtggagaaatctgtgggcccggcattgacattcgc
aacgactatcagcagctgaagcgcctggaaaactgcacggtgatcgagggcttcctccac
atcctgctcatctccaaggccgaggactaccgaagctaccgcttccccaagctcaccgtc
atcactgagtacttgctgctcttccgagtggctggccttgagagcctgggagacctcttc
cccaacctcacagtcatccggggctggaaactcttctacaactacgccttggtcatcttc
gagatgaccaatctcaaggatattgggctttataatctgaggaacattacccggggggcc
atcaggattgagaagaacgccgacctctgttacctctccaccatagactggtctctcatc
ttggatgcggtgtccaataactacattgtggggaacaagcccccaaaggaatgtggggac
ctgtgtccagggacattggaggagaagcccatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaatcgttgccagaaaatgtgcccaagtgtgtgcggg
aagcgagcctgcaccgagaacaacgagtgctgccacccggagtgcctgggcagctgccac
acaccggatgacaacacaacctgcgtggcctgcagacactactactacaaaggcgtgtgt
gtgcccgcctgcccgcctggcacctacaggttcgagggctggcgctgtgtggaccgcgat
ttctgcgccaacatccccaacgctgagagcagtgactcggatggcttcgttatccacgac
gatgagtgcatgcaggagtgtccctcaggcttcatccgcaacagcacccagagcatgtac
tgtatcccctgtgaaggcccctgccccaaagtctgcggcgatgaagagaagaaaacgaaa
accatcgattcggtgacttctgctcaaatgctccaaggatgcaccatcttgaagggcaat
ctgcttattaacatccggcgaggcaataacattgcctcggagctggagaacttcatgggg
ctcatcgaggtggtgaccggctacgtgaagatccgccattctcatgccttggtctccttg
tccttcctgaagaacctccgtctcatcttaggagaggagcagctggaagggaactactcc
ttctatgtcctggacaaccagaacttgcagcagctgtgggactggaaccaccggaacctg
accgtcaggtcggggaagatgtactttgctttcaatcccaagctgtgtgtctctgaaatt
taccgcatggaggaagtgaccggaaccaagggacgccagagcaaaggggacataaatacc
aggaacaacggagagcgagcttcctgtgaaagtgatgttctccgtttcacctctaccacg
acctggaagaaccgaatcatcattacgtggcaccggtaccggccgccggactaccgggat
ctcatcagcttcacagtttactacaaggaggcaccctttaaaaacgttacggaatatgac
gggcaggatgcctgtggctccaacagctggaacatggtggatgtagacctgcctccgaac
aaggagggcgagcctggcattttactgcatgggctgaagccctggacccagtatgctgtc
tatgtcaaggctgtgaccctcaccatggtggaaaacgaccacatccgtggggccaaaagt
gaaatcttgtacattcgcaccaatgcttcagtcccttccattcccctagatgtcctctcg
gcatcaaactcttcctctcagctgattgtgaagtggaatcccccaactctgcccaatggt
aacttgagttactacattgtgaggtggcagcggcagccccaggatggttacctgtaccgg
cacaactactgctctaaagacaaaatacccatcagaaagtacgccgatggtaccatcgac
gtggaggaggtgacggaaaatcccaagacagaagtgtgtggtggtgataaagggccatgc
tgcgcttgccctaaaactgaagctgagaagcaggctgagaaggaggaggccgagtaccgt
aaagtctttgagaatttccttcacaattccatctttgtgcccaggcccgaaaggaggcgg
agagacgtcatgcaagtggccaacacgaccatgtccagccgaagcaggaacaccacagta
gctgacacctacaatatcacagacccggaggagttcgagacagagtaccctttctttgag
agcagagtggataacaaggagaggactgtcatctccaacctccggcctttcactctgtac
cgaatcgatatccacagctgcaaccacgaggctgagaagctgggctgcagtgcctccaac
ttcgtctttgcaagaaccatgccagcagaaggagctgatgatatccctggcccggtgacc
tgggagccaagacccgaaaactccatctttttaaagtggccagaacccgagaaccccaat
ggattgatcctaatgtatgaaattaaatacgggtcacaagttgaggatcagcgggaatgt
gtgtccagacaggagtacaggaagtacggaggggccaaacttaaccgtctaaacccaggg
aactatacagcccggattcaggctacctccctctctgggaatgggtcatggacagatcct
gtgttcttctatgtcccggccaaaacgacgtatgaaaacttcatgcatctgatcattgct
ctgccggttgccatcctgctgatcgttggggggctggttatcatgctgtatgtcttccat
agaaagagaaataacagcaggttgggcaatggagtgctgtatgcttctgtgaaccccgag
tatttcagcgcagctgatgtgtacgtgcctgatgaatgggaggtagctcgagagaagatc
accatgaaccgggagctcggacaagggtcctttgggatggtctatgaaggagtggccaag
ggtgtggtcaaggatgaacccgaaaccagagtggccatcaagacggtgaacgaggctgca
agtatgcgtgaaagaatcgagtttctcaacgaggcctcggtgatgaaggaattcaattgt
caccatgtggtccggttgctgggtgtggtatcccaaggccagcccaccctggtcatcatg
gaactaatgacacgtggcgatctcaaaagttatctccggtctctaaggccagaagtggag
cagaataatctagtcctcattcctccgagcttaagcaagatgatccagatggctggagag
atcgcagatggcatggcctacctcaatgccaacaagttcgtccacagagaccttgctgct
aggaactgcatggtagccgaagatttcacggtcaaaattggagattttggtatgacacga
gacatctacgagacggactactaccggaaaggtgggaaagggttgctgcctgtgcgctgg
atgtctcccgagtccctcaaggatggcgtcttcactactcattctgatgtctggtccttc
ggggtcgtcctctgggagatcgccacgctggctgagcagccctaccagggcttgtccaac
gagcaagttcttcgtttcgtcatggagggcggccttctggacaagccggacaactgcccc
gatatgctgtttgaacttatgcgcatgtgctggcagtataaccccaagatgcggccctcc
ttcctggagatcatcggcagcatcaaggatgaaatggagcccagcttccaggaggtctcc
ttctactacagcgaggagaacaagcctcccgagccggaagagctggagatggagctggag
atggagcccgagaacatggagagcgtcccactggacccctcagcctcctcagcctccctg
cctctgcctgaaagacactcaggacacaaggctgagaatggcccgggccctggtgtgctg
gttcttcgtgccagttttgatgagagacagccttacgctcacatgaacgggggacgtgcc
aacgagagggccttgcctctgccccagtcctcgacctgctga
DBGET
integrated database retrieval system
