Mus caroli (Ryukyu mouse): 110300158
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Entry
110300158 CDS
T05910
Gene name
Ikbkb
Definition
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit beta
KO
K07209
inhibitor of nuclear factor kappa-B kinase subunit beta [EC:
2.7.11.10
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal01523
Antifolate resistance
mcal04010
MAPK signaling pathway
mcal04014
Ras signaling pathway
mcal04062
Chemokine signaling pathway
mcal04064
NF-kappa B signaling pathway
mcal04068
FoxO signaling pathway
mcal04150
mTOR signaling pathway
mcal04151
PI3K-Akt signaling pathway
mcal04210
Apoptosis
mcal04380
Osteoclast differentiation
mcal04620
Toll-like receptor signaling pathway
mcal04621
NOD-like receptor signaling pathway
mcal04622
RIG-I-like receptor signaling pathway
mcal04623
Cytosolic DNA-sensing pathway
mcal04625
C-type lectin receptor signaling pathway
mcal04657
IL-17 signaling pathway
mcal04658
Th1 and Th2 cell differentiation
mcal04659
Th17 cell differentiation
mcal04660
T cell receptor signaling pathway
mcal04662
B cell receptor signaling pathway
mcal04668
TNF signaling pathway
mcal04722
Neurotrophin signaling pathway
mcal04910
Insulin signaling pathway
mcal04920
Adipocytokine signaling pathway
mcal04930
Type II diabetes mellitus
mcal04931
Insulin resistance
mcal04932
Non-alcoholic fatty liver disease
mcal05010
Alzheimer disease
mcal05132
Salmonella infection
mcal05135
Yersinia infection
mcal05142
Chagas disease
mcal05145
Toxoplasmosis
mcal05160
Hepatitis C
mcal05161
Hepatitis B
mcal05162
Measles
mcal05163
Human cytomegalovirus infection
mcal05164
Influenza A
mcal05165
Human papillomavirus infection
mcal05166
Human T-cell leukemia virus 1 infection
mcal05167
Kaposi sarcoma-associated herpesvirus infection
mcal05168
Herpes simplex virus 1 infection
mcal05169
Epstein-Barr virus infection
mcal05170
Human immunodeficiency virus 1 infection
mcal05171
Coronavirus disease - COVID-19
mcal05200
Pathways in cancer
mcal05206
MicroRNAs in cancer
mcal05212
Pancreatic cancer
mcal05215
Prostate cancer
mcal05220
Chronic myeloid leukemia
mcal05221
Acute myeloid leukemia
mcal05222
Small cell lung cancer
mcal05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mcal05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110300158 (Ikbkb)
04014 Ras signaling pathway
110300158 (Ikbkb)
04064 NF-kappa B signaling pathway
110300158 (Ikbkb)
04668 TNF signaling pathway
110300158 (Ikbkb)
04068 FoxO signaling pathway
110300158 (Ikbkb)
04151 PI3K-Akt signaling pathway
110300158 (Ikbkb)
04150 mTOR signaling pathway
110300158 (Ikbkb)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
110300158 (Ikbkb)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
110300158 (Ikbkb)
04621 NOD-like receptor signaling pathway
110300158 (Ikbkb)
04622 RIG-I-like receptor signaling pathway
110300158 (Ikbkb)
04623 Cytosolic DNA-sensing pathway
110300158 (Ikbkb)
04625 C-type lectin receptor signaling pathway
110300158 (Ikbkb)
04660 T cell receptor signaling pathway
110300158 (Ikbkb)
04658 Th1 and Th2 cell differentiation
110300158 (Ikbkb)
04659 Th17 cell differentiation
110300158 (Ikbkb)
04657 IL-17 signaling pathway
110300158 (Ikbkb)
04662 B cell receptor signaling pathway
110300158 (Ikbkb)
04062 Chemokine signaling pathway
110300158 (Ikbkb)
09152 Endocrine system
04910 Insulin signaling pathway
110300158 (Ikbkb)
04920 Adipocytokine signaling pathway
110300158 (Ikbkb)
09156 Nervous system
04722 Neurotrophin signaling pathway
110300158 (Ikbkb)
09158 Development and regeneration
04380 Osteoclast differentiation
110300158 (Ikbkb)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110300158 (Ikbkb)
05206 MicroRNAs in cancer
110300158 (Ikbkb)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110300158 (Ikbkb)
09162 Cancer: specific types
05212 Pancreatic cancer
110300158 (Ikbkb)
05221 Acute myeloid leukemia
110300158 (Ikbkb)
05220 Chronic myeloid leukemia
110300158 (Ikbkb)
05215 Prostate cancer
110300158 (Ikbkb)
05222 Small cell lung cancer
110300158 (Ikbkb)
09164 Neurodegenerative disease
05010 Alzheimer disease
110300158 (Ikbkb)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
110300158 (Ikbkb)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110300158 (Ikbkb)
04932 Non-alcoholic fatty liver disease
110300158 (Ikbkb)
04931 Insulin resistance
110300158 (Ikbkb)
09171 Infectious disease: bacterial
05132 Salmonella infection
110300158 (Ikbkb)
05135 Yersinia infection
110300158 (Ikbkb)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110300158 (Ikbkb)
05170 Human immunodeficiency virus 1 infection
110300158 (Ikbkb)
05161 Hepatitis B
110300158 (Ikbkb)
05160 Hepatitis C
110300158 (Ikbkb)
05171 Coronavirus disease - COVID-19
110300158 (Ikbkb)
05164 Influenza A
110300158 (Ikbkb)
05162 Measles
110300158 (Ikbkb)
05168 Herpes simplex virus 1 infection
110300158 (Ikbkb)
05163 Human cytomegalovirus infection
110300158 (Ikbkb)
05167 Kaposi sarcoma-associated herpesvirus infection
110300158 (Ikbkb)
05169 Epstein-Barr virus infection
110300158 (Ikbkb)
05165 Human papillomavirus infection
110300158 (Ikbkb)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110300158 (Ikbkb)
05142 Chagas disease
110300158 (Ikbkb)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
110300158 (Ikbkb)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcal01001
]
110300158 (Ikbkb)
Enzymes [BR:
mcal01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
110300158 (Ikbkb)
Protein kinases [BR:
mcal01001
]
Serine/threonine kinases: Other
IKK family [OT]
110300158 (Ikbkb)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IKBKB_SDD
IKKbetaNEMObind
ubiquitin
Motif
Other DBs
NCBI-GeneID:
110300158
NCBI-ProteinID:
XP_021025887
LinkDB
All DBs
Position
8
AA seq
524 aa
AA seq
DB search
MPSSHLSSTVCPKICIPSVPQRPVCYKLGPQPLALLQKATGEQIAIKQCRQELSPKNRDR
WCLEIQIMRRHSKVRQKSEVDIVVSEDLNGAVKFSSSLPFPNNLNSVLAERLEKWLQLML
MWHPRQRGTDPQYGPNGCFRALDDILNLKLVHVLNMVTGTVHTYPVTEDESLQSLKTRIQ
EDTGILETXQELLQEAGLVLLPDKPATQCISDSXTNEGLTLDMDLVFLFDNSKINYETQI
TPRPQPESVSCIPSDKLLLAWREMEQAVEQCGRVGDSPQGSVLLAVAGTWRYHLPLPYPI
LHMTSSLKSSDVLARVSRLVCLDSGLLSSREEQARELYRRLREKPRDQRTEGDSQEMVRL
LLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDERTVVRLQEKRQKE
LWNLLKIACSKVRGPVSGSPDSMNVSRLSHPGQLMSQPSSACDSLPESDKKSEELVAEAH
ALCSRLESALQDTVKEQDRSFTTLDWSWLQMEDEERSSLEQACD
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgccgagctctcatctgagctccaccgtgtgccccaagatttgtatccccagtgtcccc
caaaggccagtgtgctacaagcttggtccccagcctcttgcactactgcagaaggcgaca
ggtgaacagatcgccatcaagcaatgccgacaggagctcagcccaaagaacagagaccgc
tggtgccttgagatccagatcatgagaaggcactccaaagtccggcagaagagcgaagta
gacatcgttgttagtgaagatttgaatggagcagtgaagttttcaagttcgctacccttc
cccaataatcttaacagtgtcctggctgaacggctggagaagtggctgcagctgatgctt
atgtggcaccctcggcaaaggggcacagatccccagtatggccccaacggctgcttcaga
gccctggatgacatcttgaacttgaagctggttcacgtcttgaacatggtcacaggcacc
gttcacacataccccgtgacggaggatgagagtctgcagagcttaaaaaccagaatccag
gaagacacagggatcctggagacagancaggagctgctgcaagaggcagggctggtgctg
ctccctgacaagcctgctactcagtgcatctcagacagcaanacaaacgagggcctcacg
ttggacatggatcttgtttttctctttgacaacagtaaaatcaactatgagactcagatc
accccccgaccccaaccggaaagtgtcagctgtatcccctcagataaattgctgctggcc
tggcgggagatggagcaggctgtggagcagtgtgggcgggtaggagactcaccccagggc
tctgtgcttctggctgtggccggaacttggcgctaccatcttccactcccttatccaata
ctgcatatgaccagtagtctaaaaagtagtgatgtgctggcaagagttagcaggctggtg
tgccttgactctggccttctctcttccagggaggaacaagcgagggagctctaccgaaga
ctcagggagaagccaagagaccaaaggacagaaggtgacagccaggagatggtacggctg
ctgcttcaggcaatccaaagctttgagaagaaagtgcgggtgatttatacacagctcagt
aagaccgtggtttgtaagcagaaggcactggagctgctgcccaaggtagaagaggtggtg
agccttatgaacgaggacgagaggaccgtggtccggcttcaggagaagcggcagaaggag
ctctggaacctcctgaagatcgcctgtagcaaagtccgaggtcccgtgagtggaagccca
gacagcatgaatgtgtctcgactcagtcaccctggtcagctaatgtcccagccttccagt
gcctgtgacagcttacctgaatcagacaagaaaagtgaagaactggtggccgaagcccac
gccctctgctcccggctagaaagtgcnctgcaggacacggtgaaggagcaagacagaagc
ttcacgactctagactggagctggttacagatggaggatgaagaaaggtctagcctggag
caggcctgtgactga
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