KEGG   Mus caroli (Ryukyu mouse): 110306201
Entry
110306201         CDS       T05910                                 

Gene name
Stat3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal01521  EGFR tyrosine kinase inhibitor resistance
mcal04062  Chemokine signaling pathway
mcal04066  HIF-1 signaling pathway
mcal04068  FoxO signaling pathway
mcal04217  Necroptosis
mcal04550  Signaling pathways regulating pluripotency of stem cells
mcal04630  JAK-STAT signaling pathway
mcal04659  Th17 cell differentiation
mcal04917  Prolactin signaling pathway
mcal04920  Adipocytokine signaling pathway
mcal04931  Insulin resistance
mcal04933  AGE-RAGE signaling pathway in diabetic complications
mcal04935  Growth hormone synthesis, secretion and action
mcal05145  Toxoplasmosis
mcal05160  Hepatitis C
mcal05161  Hepatitis B
mcal05162  Measles
mcal05163  Human cytomegalovirus infection
mcal05167  Kaposi sarcoma-associated herpesvirus infection
mcal05169  Epstein-Barr virus infection
mcal05200  Pathways in cancer
mcal05203  Viral carcinogenesis
mcal05205  Proteoglycans in cancer
mcal05206  MicroRNAs in cancer
mcal05212  Pancreatic cancer
mcal05221  Acute myeloid leukemia
mcal05223  Non-small cell lung cancer
mcal05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mcal05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    110306201 (Stat3)
   04066 HIF-1 signaling pathway
    110306201 (Stat3)
   04068 FoxO signaling pathway
    110306201 (Stat3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    110306201 (Stat3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    110306201 (Stat3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    110306201 (Stat3)
   04062 Chemokine signaling pathway
    110306201 (Stat3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    110306201 (Stat3)
   04917 Prolactin signaling pathway
    110306201 (Stat3)
   04935 Growth hormone synthesis, secretion and action
    110306201 (Stat3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110306201 (Stat3)
   05206 MicroRNAs in cancer
    110306201 (Stat3)
   05205 Proteoglycans in cancer
    110306201 (Stat3)
   05203 Viral carcinogenesis
    110306201 (Stat3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110306201 (Stat3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    110306201 (Stat3)
   05221 Acute myeloid leukemia
    110306201 (Stat3)
   05223 Non-small cell lung cancer
    110306201 (Stat3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    110306201 (Stat3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    110306201 (Stat3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    110306201 (Stat3)
  09172 Infectious disease: viral
   05162 Measles
    110306201 (Stat3)
   05161 Hepatitis B
    110306201 (Stat3)
   05160 Hepatitis C
    110306201 (Stat3)
   05163 Human cytomegalovirus infection
    110306201 (Stat3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110306201 (Stat3)
   05169 Epstein-Barr virus infection
    110306201 (Stat3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110306201 (Stat3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    110306201 (Stat3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mcal03000]
    110306201 (Stat3)
Transcription factors [BR:mcal03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    110306201 (Stat3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 110306201
NCBI-ProteinID: XP_021034058
Ensembl: MGP_CAROLIEiJ_G0017190
LinkDB
Position
11
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggctcagtggaaccagctgcagcagctggacacacgctacctggagcagctgcaccag
ctgtacagcgacagcttccccatggagctgcgccagttcctggcaccttggattgagagt
caagactgggcatatgcagccagcaaagagtcacatgccacgttggtgtttcataatctc
ttgggtgaaattgaccagcaatatagccgattcctgcaagagtccaatgtcctctatcag
cacaaccttcgaagaatcaagcagtttctgcagagcaggtatcttgagaagccaatggaa
attgcccggatcgtggcccgatgcctgtgggaagagtctcgcctcctccagacggcagcc
acggcagcccagcaagggggccaggccaaccacccaacagccgccgtagtgacagagaag
cagcagatgttggagcagcatcttcaggatgtccggaagcgagtgcaggatctagaacag
aaaatgaaggtggtggagaacctccaggacgactttgatttcaactacaaaaccctcaag
agccaaggagacatgcaggatctgaatggaaacaaccagtctgtgaccagacagaagatg
cagcagctggaacagatgctcacagccctggaccagatgcggagaagcattgtgagtgag
ctggcggggctcttgtcagcaatggagtacgtgcagaagacgctgactgatgaagagctg
gctgactggaagaggcggcagcagatcgcgtgtatcggaggccctcccaacatctgcctg
gaccgtctggaaaactggataacttcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagctgcagcagaaagtgtcctacaagggcgaccctatcgtgcag
caccggcccatgctggaggagaggattgtggagctgttcagaaacttaatgaagagtgcc
ttcgtggtggagcggcagccctgcatgcccatgcacccggaccggcccttagtcatcaag
actggtgtccagtttaccacgaaagtcaggttgctggtcaaatttcctgagttgaattat
cagcttaaaattaaagtgtgcattgataaagactctggggatgttgctgccctcagaggg
tctcggaaatttaacattctgggcacgaacacaaaagtgatgaacatggaggagtctaac
aacggcagcctgtctgcagagttcaagcacctgacccttagggagcagagatgtgggaat
ggaggccgtgccaattgtgatgcctccttgattgtgactgaggagctgcacctgatcacc
ttcgagacggaggtgtaccaccaaggcctcaagattgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcttgggcatcaatcctgtggtat
aatatgctgaccaataaccccaagaacgtgaacttcttcactaagccgccaattggaacc
tgggaccaagtggccgaggtgctcagctggcagttctcgtccaccaccaagcgggggctg
agcatcgagcagctgacaacgctggctgagaagcttctagggcctggtgtgaactactca
gggtgtcagatcacatgggctaaattctgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctagacaatatcatcgaccttgtgaaaaagtatatcttggccctttgg
aatgaagggtacatcatgggtttcatcagcaaggagcgggagcgagccatcctaagcaca
aagcccccgggcaccttcctactgcgcttcagcgagagcagcaaagaaggaggggtcact
ttcacttgggtggaaaaggacatcagtggcaagacccagatccagtctgtagagccatat
accaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gatgcgaccaacatcctggtgtctccacttgtctacctctaccctgacattcccaaggag
gaggcattcggaaagtactgtaggcccgagagccaggagcaccccgaagctgacccaggt
agtgctgccccgtacctgaagaccaagttcatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataac
ggtgaaggtgctgagccctcagcaggagggcagtttgagtcgctcacgtttgacatggat
ctgacctcggagtgtgctacctcccccatgtga

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