KEGG   Macaca mulatta (rhesus monkey): 574128
Entry
574128            CDS       T01028                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc01521  EGFR tyrosine kinase inhibitor resistance
mcc04062  Chemokine signaling pathway
mcc04066  HIF-1 signaling pathway
mcc04068  FoxO signaling pathway
mcc04217  Necroptosis
mcc04550  Signaling pathways regulating pluripotency of stem cells
mcc04630  JAK-STAT signaling pathway
mcc04659  Th17 cell differentiation
mcc04917  Prolactin signaling pathway
mcc04920  Adipocytokine signaling pathway
mcc04931  Insulin resistance
mcc04933  AGE-RAGE signaling pathway in diabetic complications
mcc04935  Growth hormone synthesis, secretion and action
mcc05145  Toxoplasmosis
mcc05160  Hepatitis C
mcc05161  Hepatitis B
mcc05162  Measles
mcc05163  Human cytomegalovirus infection
mcc05167  Kaposi sarcoma-associated herpesvirus infection
mcc05169  Epstein-Barr virus infection
mcc05200  Pathways in cancer
mcc05203  Viral carcinogenesis
mcc05205  Proteoglycans in cancer
mcc05206  MicroRNAs in cancer
mcc05212  Pancreatic cancer
mcc05221  Acute myeloid leukemia
mcc05223  Non-small cell lung cancer
mcc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mcc05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    574128 (STAT3)
   04066 HIF-1 signaling pathway
    574128 (STAT3)
   04068 FoxO signaling pathway
    574128 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    574128 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    574128 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    574128 (STAT3)
   04062 Chemokine signaling pathway
    574128 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    574128 (STAT3)
   04917 Prolactin signaling pathway
    574128 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    574128 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    574128 (STAT3)
   05206 MicroRNAs in cancer
    574128 (STAT3)
   05205 Proteoglycans in cancer
    574128 (STAT3)
   05203 Viral carcinogenesis
    574128 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    574128 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    574128 (STAT3)
   05221 Acute myeloid leukemia
    574128 (STAT3)
   05223 Non-small cell lung cancer
    574128 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    574128 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    574128 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    574128 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    574128 (STAT3)
   05161 Hepatitis B
    574128 (STAT3)
   05160 Hepatitis C
    574128 (STAT3)
   05163 Human cytomegalovirus infection
    574128 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    574128 (STAT3)
   05169 Epstein-Barr virus infection
    574128 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    574128 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    574128 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mcc03000]
    574128 (STAT3)
Transcription factors [BR:mcc03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    574128 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 CDC14 Syntaxin-6_N
Other DBs
NCBI-GeneID: 574128
NCBI-ProteinID: XP_028692324
Ensembl: ENSMMUG00000010707
LinkDB
Position
16
AA seq 874 aa
MTACPGQAGAGRGLAEGAVIQRFPELRRRRPGGGAGGSDVAAEGTSPNRILDRHPGSALS
LPLGSDKPSGLREPRRPPPAHAQPRPLGLCWRNSRMAQWNQLQQLDTRYLEQLHQLYSDS
FPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRR
IKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLE
QHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGGQGVSPSSADMQDLNGNNQSVT
RQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPP
NICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNL
MKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVA
ALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEEL
HLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKP
PIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAG
KGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKE
GGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPD
IPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQ
FGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2625 nt   +upstreamnt  +downstreamnt
atgacggcgtgccccggccaggctggggctgggcggggattggctgaaggggctgtaatt
cagcggtttccggagctgcggcggcgtagaccgggagggggagccgggggttccgacgta
gcagccgagggaacaagccccaaccggatcctggacaggcaccccggctcggcgctgtct
ctccccctcggctcggataagccctccggcctgagggagccccgtcgcccgcccccggcg
cacgcgcagccccggcctctcggcctctgctggagaaacagcaggatggcccaatggaat
cagctacagcagcttgacacacggtacctggagcagctccatcagctctacagtgacagc
ttcccaatggagttgcggcagtttctggccccttggattgagagtcaagattgggcatat
gcggccagcaaagaatcacatgccactttggtgtttcataatctcctgggcgagattgac
cagcagtatagccgcttcctgcaagaatcgaatgttctctatcagcacaatctacgaaga
atcaagcagtttcttcagagcaggtatcttgagaagccaatggagattgcccggattgtg
gcccggtgcctgtgggaagagtcacgcctcctacagactgcagccactgcggcccagcaa
gggggccaggccaaccaccccacagcagctgtggtgacggagaagcagcagatgctggag
cagcaccttcaggatgtccggaagagagtacaggatctagaacagaaaatgaaagtggta
gagaatctccaggatgactttgatttcaactataaaaccctcaagagtcaaggaggtcaa
ggagtttctccttcctccgcagacatgcaagatctgaatggaaacaaccagtcagtgacc
aggcagaagatgcagcagctggaacagatgctcactgcgctggaccagatgcggagaagc
atcgtgagtgagctggcggggcttttgtcagcgatggagtacgtgcagaaaactctcaca
gacgaggagctggctgactggaagaggcggcaacagattgcctgcattggaggtccgccc
aacatctgcctagatcggctagaaaactggataacgtcattagcagaatctcaacttcag
acccgtcaacaaattaagaaactggaggagttgcagcaaaaagtgtcctacaaaggggac
cccattgtacagcaccggccgatgctggaggagagaatcgtggagctgttcagaaactta
atgaaaagtgcctttgtggtggagcggcagccctgcatgcccatgcatcccgaccggccc
cttgtcatcaagaccggcgtccagttcactaccaaagtcaggttgctggtcaaattccct
gagttaaattatcaacttaaaattaaagtgtgcattgacaaagactctggggatgttgca
gctctcagaggatcccggaaatttaacattctgggcacaaacaccaaagtgatgaacatg
gaagagtccaacaacggcagcctctctgcagaattcaaacacttgaccctgagggagcag
agatgtgggaatgggggccgagccaactgtgatgcttccctgattgtgactgaggagctg
cacctgatcacctttgagacagaggtatatcaccaaggcctcaagattgacctagagacc
cactccttgccagttgtggtgatctccaacatctgtcagatgccaaatgcctgggcgtcc
atcctgtggtacaacatgctgaccaacaaccccaagaacgtaaacttttttaccaagccc
ccaatcggaacctgggatcaagtggccgaggtcctgagctggcagttctcctccaccacc
aagcgaggactgagcatcgagcagctgactacactggcggagaaactcttgggacctggc
gtgaattattcagggtgtcagatcacatgggctaaattttgcaaagaaaacatggctggc
aagggcttctccttctgggtctggctggacaatatcattgaccttgtgaaaaagtacatc
ctggccctttggaatgaagggtacatcatgggctttatcagtaaggagcgggagcgggcc
atcttgagcaccaagcctccaggcacctttctgctaagattcagtgaaagcagcaaagaa
ggcggcgtcactttcacttgggtggagaaggacatcagtggtaagacccagatccagtcc
gtggaaccatacaccaagcagcagttgaacaacatgtcatttgctgaaatcatcatgggc
tataagatcatggatgctaccaatattctggtgtctccgctggtctatctctaccctgac
attcccaaggaggaggcattcggaaagtattgtcggccagagagccaggagcatcctgaa
gctgacccaggtagcgccgccccatacctgaagaccaagtttatctgtgtgacaccaacg
acctgcagcaataccattgacctgccgatgtccccccgcactttagattcattgatgcag
tttggaaataatggtgaaggtgctgaaccctcagcaggagggcagtttgagtccctcacc
tttgacatggagttgacctcggagtgtgctacctcccccatgtga

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