Macaca mulatta (rhesus monkey): 613027
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Entry
613027 CDS
T01028
Gene name
EGFR
Definition
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc01521
EGFR tyrosine kinase inhibitor resistance
mcc01522
Endocrine resistance
mcc04010
MAPK signaling pathway
mcc04012
ErbB signaling pathway
mcc04014
Ras signaling pathway
mcc04015
Rap1 signaling pathway
mcc04020
Calcium signaling pathway
mcc04066
HIF-1 signaling pathway
mcc04068
FoxO signaling pathway
mcc04072
Phospholipase D signaling pathway
mcc04144
Endocytosis
mcc04151
PI3K-Akt signaling pathway
mcc04510
Focal adhesion
mcc04520
Adherens junction
mcc04540
Gap junction
mcc04630
JAK-STAT signaling pathway
mcc04810
Regulation of actin cytoskeleton
mcc04912
GnRH signaling pathway
mcc04915
Estrogen signaling pathway
mcc04921
Oxytocin signaling pathway
mcc04926
Relaxin signaling pathway
mcc04928
Parathyroid hormone synthesis, secretion and action
mcc04934
Cushing syndrome
mcc05160
Hepatitis C
mcc05163
Human cytomegalovirus infection
mcc05165
Human papillomavirus infection
mcc05171
Coronavirus disease - COVID-19
mcc05200
Pathways in cancer
mcc05205
Proteoglycans in cancer
mcc05206
MicroRNAs in cancer
mcc05210
Colorectal cancer
mcc05212
Pancreatic cancer
mcc05213
Endometrial cancer
mcc05214
Glioma
mcc05215
Prostate cancer
mcc05218
Melanoma
mcc05219
Bladder cancer
mcc05223
Non-small cell lung cancer
mcc05224
Breast cancer
mcc05225
Hepatocellular carcinoma
mcc05226
Gastric cancer
mcc05230
Central carbon metabolism in cancer
mcc05231
Choline metabolism in cancer
mcc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
613027 (EGFR)
04012 ErbB signaling pathway
613027 (EGFR)
04014 Ras signaling pathway
613027 (EGFR)
04015 Rap1 signaling pathway
613027 (EGFR)
04630 JAK-STAT signaling pathway
613027 (EGFR)
04066 HIF-1 signaling pathway
613027 (EGFR)
04068 FoxO signaling pathway
613027 (EGFR)
04020 Calcium signaling pathway
613027 (EGFR)
04072 Phospholipase D signaling pathway
613027 (EGFR)
04151 PI3K-Akt signaling pathway
613027 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
613027 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
613027 (EGFR)
04520 Adherens junction
613027 (EGFR)
04540 Gap junction
613027 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
613027 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
613027 (EGFR)
04915 Estrogen signaling pathway
613027 (EGFR)
04921 Oxytocin signaling pathway
613027 (EGFR)
04926 Relaxin signaling pathway
613027 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
613027 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
613027 (EGFR)
05206 MicroRNAs in cancer
613027 (EGFR)
05205 Proteoglycans in cancer
613027 (EGFR)
05230 Central carbon metabolism in cancer
613027 (EGFR)
05231 Choline metabolism in cancer
613027 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
613027 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
613027 (EGFR)
05212 Pancreatic cancer
613027 (EGFR)
05225 Hepatocellular carcinoma
613027 (EGFR)
05226 Gastric cancer
613027 (EGFR)
05214 Glioma
613027 (EGFR)
05218 Melanoma
613027 (EGFR)
05219 Bladder cancer
613027 (EGFR)
05215 Prostate cancer
613027 (EGFR)
05213 Endometrial cancer
613027 (EGFR)
05224 Breast cancer
613027 (EGFR)
05223 Non-small cell lung cancer
613027 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
613027 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
613027 (EGFR)
05171 Coronavirus disease - COVID-19
613027 (EGFR)
05163 Human cytomegalovirus infection
613027 (EGFR)
05165 Human papillomavirus infection
613027 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
613027 (EGFR)
01522 Endocrine resistance
613027 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
613027 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mcc04147
]
613027 (EGFR)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
613027 (EGFR)
Protein kinases [BR:
mcc01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
613027 (EGFR)
Exosome [BR:
mcc04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
613027 (EGFR)
Exosomal proteins of pancreatic cancer cells
613027 (EGFR)
Exosomal proteins of bladder cancer cells
613027 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
Kinase-like
APH
GAPT
Kdo
Motif
Other DBs
NCBI-GeneID:
613027
NCBI-ProteinID:
XP_014988922
Ensembl:
ENSMMUG00000022394
UniProt:
P55245
LinkDB
All DBs
Position
3
AA seq
1210 aa
AA seq
DB search
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALA
VLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSEFLSNMSMDF
QNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGC
TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV
VTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFK
NCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAF
ENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKL
FGTSSQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCQNVSRGRECVDKCN
ILEGEPREFVENSECIQCHPECLPQVMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVM
GENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCARNGPKIPSIATGMVGALLLLLVV
ALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQ
QGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTED
SIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLN
TVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRV
APQSSEFIGA
NT seq
3633 nt
NT seq
+upstream
nt +downstream
nt
atgcgaccctccgggacggccggggccgcgctcctggcgctgctggctgcgctctgcccc
gcgagtcgggctctggaggaaaagaaagtttgccaaggcacgagtaacaaactcacgcag
ttgggcacttttgaagatcattttctcagcctccagaggatgttcaataactgtgaggtg
gtccttgggaatttggaaattacctacgtgcagaggaattatgatctttccttcttaaag
accatccaggaggtggctggttatgtcctcatcgccctcaacacagtggagcggattcct
ttggaaaacctgcagatcatcagaggaaacatgtactatgaaaattcctatgccttagca
gtcttatctaactatgatgcaaataaaaccggactgaaggagctgcccatgagaaactta
caggaaatcctgcatggcgccgtgcggttcagcaacaaccctgccctgtgcaacgtggag
agcatccagtggcgggacatagtcagcagcgagtttctcagcaacatgtcgatggacttc
cagaaccacctgggcagctgccaaaagtgtgatccaagctgtcccaatgggagctgctgg
ggtgcaggagaggagaactgccagaaactgaccaaaatcatctgtgcccagcagtgctcc
gggcgctgccgcggcaagtcccccagtgactgctgccacaaccagtgtgccgcgggctgc
acgggcccccgggagagcgactgcctggtctgccgcaaattccgagacgaagccacgtgc
aaggacacctgccccccactcatgctctacaaccccaccacataccagatggatgtgaac
cccgagggcaaatacagctttggtgccacctgcgtgaagaagtgtccccgtaattatgtg
gtgacagatcacggctcgtgcgtccgagcctgcggggccgacagctatgagatggaggaa
gacggcgtccgcaagtgtaagaagtgcgaagggccttgccgcaaagtgtgtaatggaata
ggtattggtgaatttaaagacacactctccataaatgctacaaatattaaacacttcaaa
aactgcacctccatcagtggcgatctccacatcctgccggtggcatttaggggtgactcc
ttcacacacactccgcctctggatccacaggaactggatattctgaaaaccgtaaaggaa
atcacagggtttttgctgattcaggcttggcctgaaaacaggacggacctccatgctttt
gagaacctagaaatcatacgtggcaggaccaagcaacacggtcagttttctcttgcggtc
gtcagcctgaacataacatccttgggattacgctccctcaaggagataagcgatggagat
gtgataatttcaggaaacaaaaatttgtgctatgcaaatacaataaactggaaaaaactg
tttgggacctccagtcagaaaaccaaaattataagcaacagaggtgaaaacagctgcaag
gccacgggccaggtctgccatgccttgtgctcccccgagggctgctggggcccggagccc
agggactgcgtctcctgccagaatgtcagccgaggcagagaatgcgtggacaagtgcaac
atcctggagggcgagccaagggagtttgtggagaactctgagtgcatacagtgccaccca
gaatgcctgccccaggtcatgaacatcacctgcacaggacggggaccagacaactgtatc
cagtgtgcccactacattgacggcccccactgcgtcaagacctgcccagcaggagtcatg
ggagaaaacaacaccctggtctggaagtacgcagacgccggccacgtgtgccacctgtgc
catccaaactgcacctacggatgcactgggccaggtcttgaaggctgtgcaaggaacggg
cctaagatcccatccatcgccactgggatggtgggggccctcctcttgctgctggtggtg
gccctggggatcggcctcttcatgcgaaggcgccacatcgttcggaagcgcacactgcgg
aggctgctgcaggagagggagcttgtggagcctcttacgcccagtggagaagctcccaac
caagctctcttgaggatcttgaaggaaactgaattcaagaagatcaaagtgctgggctcc
ggtgcgttcggaactgtgtataagggactctggatcccagaaggtgagaaagttaaaatt
cccgtcgctatcaaggaattaagagaagcaacatctccgaaagccaacaaggaaatcctc
gatgaagcctacgtgatggccagcgtggacaacccccatgtgtgccgcctgctgggcatc
tgcctcacctccaccgtgcagctcattacgcagctcatgcccttcggctgcctcctggac
tacgtccgggaacacaaggacaatatcggctcccagtacctgctcaactggtgtgtgcag
attgcaaagggcatgaactacttggaggaccggcgcttggtgcaccgcgacctggcagcc
aggaacgtactggtgaaaacgccacagcatgtcaagatcacggattttgggctggccaaa
ctgctgggtgcagaagagaaagaataccatgcagaaggaggcaaagtgcctatcaagtgg
atggcattggaatcaattttacaccgaatttatacccaccagagtgatgtctggagctac
ggggtgaccgtttgggagttgatgacctttggatccaagccatatgacggaatccctgcc
agcgagatctcctccatcctggagaaaggagaacgcctcccccagccacccatatgtacc
atcgatgtctacatgatcatggtcaagtgctggatgatagacgcagatagtcgcccaaag
ttccgtgagttgatcattgaattctccaaaatggcccgagacccccagcgctaccttgtt
attcagggggatgaaagaatgcatttgccaagccctacagactccaacttctaccgtgcc
ctgatggatgaagaagacatggacgacgtggtggatgccgacgagtacctcatcccacag
caaggcttcttcagcagcccctccacgtcacggactcccctcctgagctctctgagtgca
accagcaacaattccactgtggcttgcattgatagaaatgggctgcaaagctgtcccatc
aaggaagacagcttcttacagcgatacagctcagaccccacaggcgccttgactgaggac
agcatagacgacaccttcctcccagtgcctgaatacataaaccagtctgttcccaaaagg
cccgctggctctgtgcagaatcctgtctatcacaatcagcctctgaaccctgcgcccagc
agagacccacactaccaggacccccacagcaccgcagtgggcaaccccgagtatctcaac
actgtccagcccacctgtgtcaacagcacattcgacagccctgctcattgggcccagaaa
ggcagccaccaaattagcctggacaaccctgactaccagcaggacttctttcccaaggaa
gccaagccaaatggcatctttaagggctccacagctgaaaatgcagaatacctaagggtc
gcaccacaaagcagtgaatttattggagcatga
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integrated database retrieval system
