Macaca mulatta (rhesus monkey): 693914
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Entry
693914 CDS
T01028
Gene name
MAP2K6
Definition
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
KO
K04433
mitogen-activated protein kinase kinase 6 [EC:
2.7.12.2
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04010
MAPK signaling pathway
mcc04015
Rap1 signaling pathway
mcc04218
Cellular senescence
mcc04380
Osteoclast differentiation
mcc04620
Toll-like receptor signaling pathway
mcc04664
Fc epsilon RI signaling pathway
mcc04668
TNF signaling pathway
mcc04750
Inflammatory mediator regulation of TRP channels
mcc04912
GnRH signaling pathway
mcc04935
Growth hormone synthesis, secretion and action
mcc05014
Amyotrophic lateral sclerosis
mcc05022
Pathways of neurodegeneration - multiple diseases
mcc05132
Salmonella infection
mcc05135
Yersinia infection
mcc05145
Toxoplasmosis
mcc05161
Hepatitis B
mcc05163
Human cytomegalovirus infection
mcc05167
Kaposi sarcoma-associated herpesvirus infection
mcc05169
Epstein-Barr virus infection
mcc05170
Human immunodeficiency virus 1 infection
mcc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mcc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
693914 (MAP2K6)
04015 Rap1 signaling pathway
693914 (MAP2K6)
04668 TNF signaling pathway
693914 (MAP2K6)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
693914 (MAP2K6)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
693914 (MAP2K6)
04664 Fc epsilon RI signaling pathway
693914 (MAP2K6)
09152 Endocrine system
04912 GnRH signaling pathway
693914 (MAP2K6)
04935 Growth hormone synthesis, secretion and action
693914 (MAP2K6)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
693914 (MAP2K6)
09158 Development and regeneration
04380 Osteoclast differentiation
693914 (MAP2K6)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
693914 (MAP2K6)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
693914 (MAP2K6)
05022 Pathways of neurodegeneration - multiple diseases
693914 (MAP2K6)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
693914 (MAP2K6)
09171 Infectious disease: bacterial
05132 Salmonella infection
693914 (MAP2K6)
05135 Yersinia infection
693914 (MAP2K6)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
693914 (MAP2K6)
05161 Hepatitis B
693914 (MAP2K6)
05163 Human cytomegalovirus infection
693914 (MAP2K6)
05167 Kaposi sarcoma-associated herpesvirus infection
693914 (MAP2K6)
05169 Epstein-Barr virus infection
693914 (MAP2K6)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
693914 (MAP2K6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
693914 (MAP2K6)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
693914 (MAP2K6)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: STE group
STE7 family
693914 (MAP2K6)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Seadorna_VP7
Pkinase_fungal
Choline_kinase
DUF4344
APH
Motif
Other DBs
NCBI-GeneID:
693914
NCBI-ProteinID:
NP_001248635
Ensembl:
ENSMMUG00000001051
UniProt:
H9EP89
LinkDB
All DBs
Position
11
AA seq
334 aa
AA seq
DB search
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
NT seq
1005 nt
NT seq
+upstream
nt +downstream
nt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaagaagcattt
gagcaacctcagaccagttccacaccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctagagcctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggca
gtgaagcggattcgagccacagtaaatagccaggaacagaaaaggctactgatggatttg
gatatttccatgaggacggtggactgtccattcaccgtcaccttttatggcgcactgttt
cgggagggtgatgtgtggatctgcatggagctcatggacacatcactagataaattctac
aaacaagttattgataaaggccagacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcacagagacgtc
aagccttctaatgtactcattaatgctctcggtcaagtgaagatgtgcgattttggaatc
agtggctacttggtggactctgttgctaaaacaattgatgcgggttgcaaaccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacgatgattgagttggccatccttcgatttccctatgattcctgg
ggaactccatttcagcagctcaaacaggtggtagaggagccatctccacaactcccagca
gacaagttctctgcagagttcgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggcctacatacccagagctaatgcaacatccatttttcaccctacatgaatccaaa
ggaacagatgtggcatcttttgtaaaactgattcttggagattaa
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