KEGG   Macaca mulatta (rhesus monkey): 696759
Entry
696759            CDS       T01028                                 

Gene name
KIT
Definition
(RefSeq) mast/stem cell growth factor receptor Kit precursor
  KO
K05091  proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc04010  MAPK signaling pathway
mcc04014  Ras signaling pathway
mcc04015  Rap1 signaling pathway
mcc04072  Phospholipase D signaling pathway
mcc04151  PI3K-Akt signaling pathway
mcc04640  Hematopoietic cell lineage
mcc04916  Melanogenesis
mcc05200  Pathways in cancer
mcc05221  Acute myeloid leukemia
mcc05224  Breast cancer
mcc05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    696759 (KIT)
   04014 Ras signaling pathway
    696759 (KIT)
   04015 Rap1 signaling pathway
    696759 (KIT)
   04072 Phospholipase D signaling pathway
    696759 (KIT)
   04151 PI3K-Akt signaling pathway
    696759 (KIT)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    696759 (KIT)
  09152 Endocrine system
   04916 Melanogenesis
    696759 (KIT)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    696759 (KIT)
   05230 Central carbon metabolism in cancer
    696759 (KIT)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    696759 (KIT)
   05224 Breast cancer
    696759 (KIT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcc01001]
    696759 (KIT)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mcc04090]
    696759 (KIT)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     696759 (KIT)
Protein kinases [BR:mcc01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   696759 (KIT)
CD molecules [BR:mcc04090]
 Proteins
  696759 (KIT)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 Ig_6 Ig_4 V-set CshA_NR2 Pkinase_fungal APH
Other DBs
NCBI-GeneID: 696759
NCBI-ProteinID: NP_001253024
UniProt: F6V858 H9FU75
LinkDB
Position
5
AA seq 976 aa
MRGARGAWDFLCVLLFLLHVQTGSSQPSVSPGEPSPPSIHPAKSELIVRVGNEIRLLCID
PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSSSIYVFVRDPAKLFLV
DRSLYGKEDNDTLVRCPLTDPEVTSYSLKGCQGKPLPKDLRFVPDPKAGITIKSVKRAYH
RLCLHCSADQEGKSVLSDKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNASIAFNVYVNTKPEILTYDR
LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNASGPPFGKLVVQSSIDS
SAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIV
MILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAF
GKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGAC
TIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAESALYKNLLHSKESSCSDSTNE
YMDMKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGM
AFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPES
IFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMY
DIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSV
GSTASSSQPLLVHDDV
NT seq 2931 nt   +upstreamnt  +downstreamnt
atgagaggcgctcgcggcgcctgggattttctctgcgttctgctcttcctgctccacgtc
cagacaggctcttctcaaccatctgtgagtccaggggaaccgtctccaccatccatccat
ccagcaaaatcagagttaatagtccgcgtgggcaacgagattaggctgttgtgcattgat
ccaggctttgtcaaatggacttttgagatcctggatgaaacgaatgagaataagcagaat
gaatggatcacagaaaaggcagaggccaccaacaccggcaaatacacgtgcaccaacaaa
cacggcttaagcagttccatttatgtgtttgttagagatcctgccaagcttttccttgtt
gaccgctccttgtatgggaaagaagacaatgacacactggtccgctgtcctctcacagac
ccagaagtgaccagttattccctcaaggggtgccaggggaagcctcttcccaaggacttg
aggtttgttcctgaccccaaggctggcatcacgatcaaaagcgtgaaacgcgcctaccat
cggctctgtctgcattgttccgcggaccaggagggcaagtcagtgctgtcggacaagttc
atcctgaaagtgaggccagccttcaaagctgtgcctgttgtgtctgtttccaaagcaagc
tatcttcttagggaaggggaagaattcacagtgacatgcacaataaaagatgtgtctagt
tctgtgtactcaacgtggaaaagagaaaacagtcagactaaactacaggagaaatataat
agctggcatcacggtgacttcaattatgaacgtcaggcaacgttgactatcagttcagcg
agagttaatgattctggagtgttcatgtgttatgccaataatacttttggatcagcaaat
gtcacaacaaccttggaagtagtagataaaggattcattaatatcttccccatgataaac
actacagtatttgtaaacgatggagaaaatgtagatttgattgttgaatatgaggcattc
cccaaacctgaacaccagcagtggatctatatgaacagaaccttcactgataaatgggaa
gattatcccaagtctgagaatgaaagtaatatcagatacgtaagtgaacttcatctaacc
agattaaaaggcactgaaggaggcacttacacattcctagtgtccaattctgacgtcaat
gcttccatagcatttaatgtttatgtgaatacaaaaccagaaatcctgacttacgacagg
ctcgtgaatggcatgctccaatgtgtggcagcaggattcccagaacccacaatagattgg
tatttttgtccgggaactgagcagagatgctctgcttctgtactgccagtggatgtgcag
acactaaacgcatctgggccaccgtttggaaaactagtggttcagagttccatagattct
agtgcattcaagcacaatggcacggttgaatgtaaggcttacaacgatgtgggcaagact
tctgcctattttaactttgcatttaaaggtaacaacaaagagcaaatccatccccacacc
ctgttcactcctttgctgattggttttgtaatcgtagctggcatgatgtgcattattgtg
atgattctcacctacaaatatttacagaaacccatgtatgaagtacagtggaaggttgtt
gaggagataaatggaaacaattacgtttacatagacccaacacaacttccttatgatcac
aaatgggagtttcccagaaacaggctgagttttgggaaaaccctgggtgctggcgctttt
gggaaggttgttgaggcaactgcttatggcttaattaagtcggacgcagccatgactgtc
gctgtaaagatgctcaaaccaagtgcccatttaacagaacgagaagccctcatgtctgaa
ctcaaagtcctgagttaccttggtaatcatatgaatattgtgaatcttcttggagcctgc
accattggagggcccaccctggtcattacagaatattgttgctatggtgatcttttgaat
tttttgagaagaaaacgtgattcttttatttgttcaaagcaggaagatcatgcagaatct
gcactttataagaatcttctgcattcaaaggagtcttcctgcagcgatagtactaatgag
tacatggacatgaaacctggagtttcttatgtcgtcccaaccaaggctgacaaaaggaga
tctgcgagaataggctcatatatagaaagagatgtgacacccgccatcatggaggatgac
gagttggctttagacttagaagacttgctgagcttttcttaccaggtggcaaagggcatg
gctttccttgcctccaagaattgtattcacagagacttggcagccagaaatatcctcctt
actcatggtcggatcacaaagatttgtgattttggcctagccagagacatcaagaatgat
tctaattatgtggttaaaggaaatgctcgactacctgtgaagtggatggcacctgaaagc
attttcaactgtgtgtacacatttgaaagtgacgtctggtcctatgggatttttctttgg
gagctattctctttaggaagcagcccctatcctggaatgccagtcgattctaaattctac
aagatgatcaaggaaggcttccggatgctcagccctgaacatgcacctgctgaaatgtat
gacataatgaagacttgctgggatgcggatcccctaaaaagaccaacattcaagcaaatt
gttcagctaattgagaagcagatttcagagagcaccaatcatatttactccaacttagca
aactgcagccccaaccgacagaagcctgtagtggaccattccgtgcggatcaattctgtc
ggcagcaccgcttcctcctcccaacctctgcttgtgcacgacgacgtctga

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