KEGG   Macaca mulatta (rhesus monkey): 702041
Entry
702041            CDS       T01028                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc01521  EGFR tyrosine kinase inhibitor resistance
mcc01522  Endocrine resistance
mcc04010  MAPK signaling pathway
mcc04012  ErbB signaling pathway
mcc04014  Ras signaling pathway
mcc04062  Chemokine signaling pathway
mcc04068  FoxO signaling pathway
mcc04072  Phospholipase D signaling pathway
mcc04150  mTOR signaling pathway
mcc04151  PI3K-Akt signaling pathway
mcc04380  Osteoclast differentiation
mcc04510  Focal adhesion
mcc04540  Gap junction
mcc04550  Signaling pathways regulating pluripotency of stem cells
mcc04630  JAK-STAT signaling pathway
mcc04650  Natural killer cell mediated cytotoxicity
mcc04660  T cell receptor signaling pathway
mcc04662  B cell receptor signaling pathway
mcc04664  Fc epsilon RI signaling pathway
mcc04714  Thermogenesis
mcc04722  Neurotrophin signaling pathway
mcc04910  Insulin signaling pathway
mcc04912  GnRH signaling pathway
mcc04915  Estrogen signaling pathway
mcc04917  Prolactin signaling pathway
mcc04926  Relaxin signaling pathway
mcc04935  Growth hormone synthesis, secretion and action
mcc05034  Alcoholism
mcc05160  Hepatitis C
mcc05161  Hepatitis B
mcc05163  Human cytomegalovirus infection
mcc05165  Human papillomavirus infection
mcc05200  Pathways in cancer
mcc05203  Viral carcinogenesis
mcc05205  Proteoglycans in cancer
mcc05206  MicroRNAs in cancer
mcc05210  Colorectal cancer
mcc05211  Renal cell carcinoma
mcc05213  Endometrial cancer
mcc05214  Glioma
mcc05215  Prostate cancer
mcc05220  Chronic myeloid leukemia
mcc05221  Acute myeloid leukemia
mcc05223  Non-small cell lung cancer
mcc05224  Breast cancer
mcc05225  Hepatocellular carcinoma
mcc05226  Gastric cancer
mcc05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    702041 (GRB2)
   04012 ErbB signaling pathway
    702041 (GRB2)
   04014 Ras signaling pathway
    702041 (GRB2)
   04630 JAK-STAT signaling pathway
    702041 (GRB2)
   04068 FoxO signaling pathway
    702041 (GRB2)
   04072 Phospholipase D signaling pathway
    702041 (GRB2)
   04151 PI3K-Akt signaling pathway
    702041 (GRB2)
   04150 mTOR signaling pathway
    702041 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    702041 (GRB2)
   04540 Gap junction
    702041 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    702041 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    702041 (GRB2)
   04660 T cell receptor signaling pathway
    702041 (GRB2)
   04662 B cell receptor signaling pathway
    702041 (GRB2)
   04664 Fc epsilon RI signaling pathway
    702041 (GRB2)
   04062 Chemokine signaling pathway
    702041 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    702041 (GRB2)
   04912 GnRH signaling pathway
    702041 (GRB2)
   04915 Estrogen signaling pathway
    702041 (GRB2)
   04917 Prolactin signaling pathway
    702041 (GRB2)
   04926 Relaxin signaling pathway
    702041 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    702041 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    702041 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    702041 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    702041 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    702041 (GRB2)
   05206 MicroRNAs in cancer
    702041 (GRB2)
   05205 Proteoglycans in cancer
    702041 (GRB2)
   05203 Viral carcinogenesis
    702041 (GRB2)
   05231 Choline metabolism in cancer
    702041 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    702041 (GRB2)
   05225 Hepatocellular carcinoma
    702041 (GRB2)
   05226 Gastric cancer
    702041 (GRB2)
   05214 Glioma
    702041 (GRB2)
   05221 Acute myeloid leukemia
    702041 (GRB2)
   05220 Chronic myeloid leukemia
    702041 (GRB2)
   05211 Renal cell carcinoma
    702041 (GRB2)
   05215 Prostate cancer
    702041 (GRB2)
   05213 Endometrial cancer
    702041 (GRB2)
   05224 Breast cancer
    702041 (GRB2)
   05223 Non-small cell lung cancer
    702041 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    702041 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    702041 (GRB2)
   05160 Hepatitis C
    702041 (GRB2)
   05163 Human cytomegalovirus infection
    702041 (GRB2)
   05165 Human papillomavirus infection
    702041 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    702041 (GRB2)
   01522 Endocrine resistance
    702041 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mcc04131]
    702041 (GRB2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:mcc04990]
    702041 (GRB2)
Membrane trafficking [BR:mcc04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    702041 (GRB2)
Domain-containing proteins not elsewhere classified [BR:mcc04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   702041 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 702041
NCBI-ProteinID: XP_014975798
Ensembl: ENSMMUG00000004756
UniProt: G7NGP6 A0A1D5QBC1
LinkDB
Position
16
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
cttaatggaaaagacggcttcattcccaagaactacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcctttcttatccgagagagtgagagcgctcctggggacttctccctctctgtcaag
tttggaaacgatgtgcagcacttcaaggtgctccgagacggagccggcaagtacttcctc
tgggtggtgaagttcaattctttgaatgagctggtggattatcacagatctacatctgtc
tccagaaaccagcagatattcctgcgggacatagaacaggtgccacagcagccgacatac
gtccaggccctctttgactttgatcctcaggaggatggagagctgggcttccgccgggga
gattttatccatgtcatggataactcagaccccaactggtggaaaggagcttgccacggg
cagaccggcatgtttccccgcaattacgtcacccccgtgaaccggaacgtctaa

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