Macaca mulatta (rhesus monkey): 702781 Help Entry 702781            CDS       T01028                                  Gene name CASP8 Definition (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc01524   Platinum drug resistance mcc04115   p53 signaling pathway mcc04210   Apoptosis mcc04215   Apoptosis - multiple species mcc04217   Necroptosis mcc04620   Toll-like receptor signaling pathway mcc04621   NOD-like receptor signaling pathway mcc04622   RIG-I-like receptor signaling pathway mcc04625   C-type lectin receptor signaling pathway mcc04657   IL-17 signaling pathway mcc04668   TNF signaling pathway mcc04932   Non-alcoholic fatty liver disease mcc05010   Alzheimer disease mcc05016   Huntington disease mcc05022   Pathways of neurodegeneration - multiple diseases mcc05132   Salmonella infection mcc05134   Legionellosis mcc05142   Chagas disease mcc05145   Toxoplasmosis mcc05152   Tuberculosis mcc05160   Hepatitis C mcc05161   Hepatitis B mcc05162   Measles mcc05163   Human cytomegalovirus infection mcc05164   Influenza A mcc05165   Human papillomavirus infection mcc05167   Kaposi sarcoma-associated herpesvirus infection mcc05168   Herpes simplex virus 1 infection mcc05169   Epstein-Barr virus infection mcc05170   Human immunodeficiency virus 1 infection mcc05200   Pathways in cancer mcc05203   Viral carcinogenesis mcc05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:mcc00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     702781 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     702781 (CASP8)    04215 Apoptosis - multiple species     702781 (CASP8)    04217 Necroptosis     702781 (CASP8)    04115 p53 signaling pathway     702781 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     702781 (CASP8)    04621 NOD-like receptor signaling pathway     702781 (CASP8)    04622 RIG-I-like receptor signaling pathway     702781 (CASP8)    04625 C-type lectin receptor signaling pathway     702781 (CASP8)    04657 IL-17 signaling pathway     702781 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     702781 (CASP8)    05203 Viral carcinogenesis     702781 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     702781 (CASP8)    05016 Huntington disease     702781 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     702781 (CASP8)   09166 Cardiovascular disease    05416 Viral myocarditis     702781 (CASP8)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     702781 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     702781 (CASP8)    05134 Legionellosis     702781 (CASP8)    05152 Tuberculosis     702781 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     702781 (CASP8)    05161 Hepatitis B     702781 (CASP8)    05160 Hepatitis C     702781 (CASP8)    05164 Influenza A     702781 (CASP8)    05162 Measles     702781 (CASP8)    05168 Herpes simplex virus 1 infection     702781 (CASP8)    05163 Human cytomegalovirus infection     702781 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     702781 (CASP8)    05169 Epstein-Barr virus infection     702781 (CASP8)    05165 Human papillomavirus infection     702781 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     702781 (CASP8)    05142 Chagas disease     702781 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     702781 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mcc01002]     702781 (CASP8) Enzymes [BR:mcc01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      702781 (CASP8) Peptidases and inhibitors [BR:mcc01002]  Cysteine peptidases   Family C14: caspase family    702781 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  702781 NCBI-ProteinID:  XP_014966130 Ensembl:  ENSMMUG00000031296 LinkDB All DBs Position 12 AA seq 496 aa AA seqDB search MVPGKGGADYILLPFEEMDFNRNLYDIGEQLDSEELASLKFLSLDCIPQRKQEPIKDALM LFQRLQEKRMLEENNLSFLKELLFRINRLDLLTTYLNTRKEEMERELQAPGRAQISAYRV MLYQISEEVGRSELRSFKFLLQEEISKCKLDDDMNLLDIFVEMEKRVILGEGKLDILKRV CAQVNKSLLKIINDYEEFSRERTRSLEGSPEEGSNGEELCGLMTISDSPREQDSESQTLD KVYQMKSKPRGYCLIINNYDFTKAREKVPKLHSIRDRNGTHLDAEALTATFEELHFEIQH HNDCTVEKIYKILKTYQLMDHSNKDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGL KCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGM ATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQM PQPTFTLRKKLVFPSD NT seq 1491 nt NT seq  +upstreamnt  +downstreamnt atggtgccaggaaagggtggagcggattatattctgctgccttttgaagagatggacttc aacagaaatctttatgatattggggaacaactggacagtgaagagctggcctccctcaag ttcctgagcctggactgcatcccacaaaggaagcaagaacccatcaaagatgccttgatg ttattccagagactccaggaaaagagaatgttggaggaaaacaatctgtccttcctgaag gagctgctcttccgaattaatagactggatttgctcactacttacctaaacactagaaag gaggagatggaaagggaacttcaggcaccaggcagggctcagatttctgcctacagggtc atgctctatcagatttcagaagaggtgggcagatcagaattgaggtcttttaagtttctt ctgcaagaggagatctccaaatgcaaactggatgatgacatgaacctgctggatattttc gtagagatggagaagagggtcatcctgggagaaggcaagttggacatcctgaagagagtc tgtgcccaagtcaacaagagcctgctgaagataatcaatgactatgaagaattcagcaga gagagaacaaggagccttgaaggaagtcctgaggaaggttcaaatggggaggagttgtgt gggctaatgacaatctcggactctccaagagaacaggatagtgaatcacagactttggac aaagtttaccaaatgaaaagcaaacctcggggatactgtctgatcatcaacaattacgat tttacgaaagcacgggagaaagtgcccaaacttcacagcattagggacaggaatggaaca cacttggatgcagaggctttgaccgcgacctttgaagagcttcattttgagatccagcac cacaatgactgcacagtagagaaaatctataagattttgaaaacctaccaactcatggac cacagtaacaaggattgcttcatctgctgtatcctctcccatggagacaagggcatcatc tatggcactgatggacaggaggcccccatctatgagctgacatctcagttcactggtttg aagtgcccttcccttgctggaaaacccaaagtgttttttattcaggcttgtcagggggat aactaccagaaaggtatacctgttgagactgattcagaggagcaaccctatttggaaatg gatttatcatcacctcaaacgagatatatcccggatgaggctgactttctgctggggatg gccactgtgaataactgtgtttcctaccgaaaccctgcagagggaacctggtacatccag tcactttgccagagcctgagagaacgatgtcctcgaggcgatgatattctcaccatcctg actgaagtgaactatgaagtaagcaacaaggatgacaagaaaaacatggggaaacagatg ccgcagccaactttcacactaagaaaaaaacttgtcttcccttctgattga

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