KEGG   Macaca mulatta (rhesus monkey): 703088
Entry
703088            CDS       T01028                                 

Gene name
TGFBR2
Definition
(RefSeq) TGF-beta receptor type-2 precursor
  KO
K04388  TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc04010  MAPK signaling pathway
mcc04060  Cytokine-cytokine receptor interaction
mcc04068  FoxO signaling pathway
mcc04144  Endocytosis
mcc04218  Cellular senescence
mcc04350  TGF-beta signaling pathway
mcc04380  Osteoclast differentiation
mcc04390  Hippo signaling pathway
mcc04520  Adherens junction
mcc04659  Th17 cell differentiation
mcc04926  Relaxin signaling pathway
mcc04933  AGE-RAGE signaling pathway in diabetic complications
mcc05142  Chagas disease
mcc05161  Hepatitis B
mcc05166  Human T-cell leukemia virus 1 infection
mcc05200  Pathways in cancer
mcc05202  Transcriptional misregulation in cancer
mcc05210  Colorectal cancer
mcc05212  Pancreatic cancer
mcc05220  Chronic myeloid leukemia
mcc05225  Hepatocellular carcinoma
mcc05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    703088 (TGFBR2)
   04350 TGF-beta signaling pathway
    703088 (TGFBR2)
   04390 Hippo signaling pathway
    703088 (TGFBR2)
   04068 FoxO signaling pathway
    703088 (TGFBR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    703088 (TGFBR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    703088 (TGFBR2)
  09143 Cell growth and death
   04218 Cellular senescence
    703088 (TGFBR2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    703088 (TGFBR2)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    703088 (TGFBR2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    703088 (TGFBR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    703088 (TGFBR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    703088 (TGFBR2)
   05202 Transcriptional misregulation in cancer
    703088 (TGFBR2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    703088 (TGFBR2)
   05212 Pancreatic cancer
    703088 (TGFBR2)
   05225 Hepatocellular carcinoma
    703088 (TGFBR2)
   05226 Gastric cancer
    703088 (TGFBR2)
   05220 Chronic myeloid leukemia
    703088 (TGFBR2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    703088 (TGFBR2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    703088 (TGFBR2)
   05161 Hepatitis B
    703088 (TGFBR2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    703088 (TGFBR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcc01001]
    703088 (TGFBR2)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     703088 (TGFBR2)
Protein kinases [BR:mcc01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   703088 (TGFBR2)
SSDB
Motif
Pfam: ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal APH
Other DBs
NCBI-GeneID: 703088
NCBI-ProteinID: NP_001248080
Ensembl: ENSMMUG00000010031
UniProt: H9YUL0
LinkDB
Position
2
AA seq 567 aa
MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSVNNDMMVTDNNGAVKFPQLCKFCDVRFST
CDNQKSCLSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPK
CIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAI
SVIIIFYCYRVNRQQKLSSSWEAGKPRKLMDFSEHCAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq 1704 nt   +upstreamnt  +downstreamnt
atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcctgtggacgcgtatc
gccagcacgatcccaccgcacgttcagaagtcggttaacaatgacatgatggtcactgac
aacaatggtgcagtcaagtttccacaactgtgtaaattttgtgatgtgagattttccacc
tgtgacaaccagaaatcctgcctgagcaactgcagcatcacctccatctgtgaaaagcca
caggaagtctgtgtggctgtatggagaaagaatgacgagaacataacactagagacagtt
tgccatgatcccaagctcccctaccatgactttattctggaagatgctgcttctccaaag
tgcattatgaaggaaaaaaaaaagcctggtgagactttcttcatgtgttcctgtagctct
gatgagtgcaatgacaacatcatcttctcagaagaatacaacaccagcaatcctgacttg
ttgctagtcatatttcaagtgacaggcatcagcctcctgccaccactgggagttgccata
tctgtcatcatcatcttctactgctaccgcgttaaccggcagcagaagctgagctcatcc
tgggaagctggcaagccacggaagctcatggacttcagcgagcactgtgccatcatcctg
gaagacgaccgctccgacatcagctccacatgcgccaacaacatcaaccacaacacagag
ctgctgcccattgaactggacaccctggtggggaaaggtcgctttgctgaggtctataag
gccaagctgaagcagaacacttcagagcagtttgagacagtggcagtcaagatctttccc
tatgaggagtatgcctcttggaagacggagaaggacatcttctcagacatcaacctgaag
catgagaacatactccagttcctgacagctgaggagcgcaagacggagttggggaagcag
tactggctgatcactgccttccatgccaagggcaacctacaggagtacctgacgcggcat
gtcatcagctgggaggacctgcgcaaactgggcagctccctcgcccggggcattgcccac
ctccacagtgatcacactccgtgcgggaggcccaagatgcccatcgtgcacagggacctc
aagagctccaatatcctcgtgaagaacgacctgacctgctgcctgtgtgactttgggctt
tccctgcgtctggaccctactctgtctgtggatgacctggctaacagcgggcaggtggga
actgcaagatacatggctccagaagtcctagaatccaggatgaatttggagaatgtagag
tcctttaagcagaccgatgtctactccatggctctggtgctctgggaaatgacatcgcgc
tgtaatgcggtgggagaagtaaaagattatgagcctccatttggttccaaggtgcgggag
cacccctgtgtcgaaagcatgaaggacaacgtgttgagagatcgaggacgaccagaaatt
cccagcttctggctcaaccaccagggcatccagatggtgtgtgagacgttgactgagtgc
tgggaccacgacccagaggcccgcctcacagcccagtgtgtggcagaacgcttcagtgag
ctggagcacctggacaggctctcggggaggagctgctccgaggagaagattcctgaagac
ggctccctaaacactaccaaatag

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