KEGG   Macaca mulatta (rhesus monkey): 704102
Entry
704102            CDS       T01028                                 

Gene name
SYK
Definition
(RefSeq) tyrosine-protein kinase SYK
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc04064  NF-kappa B signaling pathway
mcc04072  Phospholipase D signaling pathway
mcc04151  PI3K-Akt signaling pathway
mcc04380  Osteoclast differentiation
mcc04611  Platelet activation
mcc04613  Neutrophil extracellular trap formation
mcc04625  C-type lectin receptor signaling pathway
mcc04650  Natural killer cell mediated cytotoxicity
mcc04662  B cell receptor signaling pathway
mcc04664  Fc epsilon RI signaling pathway
mcc04666  Fc gamma R-mediated phagocytosis
mcc05152  Tuberculosis
mcc05167  Kaposi sarcoma-associated herpesvirus infection
mcc05168  Herpes simplex virus 1 infection
mcc05169  Epstein-Barr virus infection
mcc05171  Coronavirus disease - COVID-19
mcc05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    704102 (SYK)
   04072 Phospholipase D signaling pathway
    704102 (SYK)
   04151 PI3K-Akt signaling pathway
    704102 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    704102 (SYK)
   04613 Neutrophil extracellular trap formation
    704102 (SYK)
   04625 C-type lectin receptor signaling pathway
    704102 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    704102 (SYK)
   04662 B cell receptor signaling pathway
    704102 (SYK)
   04664 Fc epsilon RI signaling pathway
    704102 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    704102 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    704102 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    704102 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    704102 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    704102 (SYK)
   05168 Herpes simplex virus 1 infection
    704102 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    704102 (SYK)
   05169 Epstein-Barr virus infection
    704102 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcc01001]
    704102 (SYK)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     704102 (SYK)
Protein kinases [BR:mcc01001]
 Non-receptor tyrosine kinases
  SYK family
   704102 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo RIO1
Other DBs
NCBI-GeneID: 704102
NCBI-ProteinID: NP_001247964
Ensembl: ENSMMUG00000001748
UniProt: F7GLV6 G7NES2
LinkDB
Position
15
AA seq 635 aa
MASSGMADNANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
PGHRKPSPAQGNRPESTVSFNPYEPEVAPWAAEKGPQREALPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
NT seq 1908 nt   +upstreamnt  +downstreamnt
atggccagcagcggcatggctgacaacgccaaccacctgcccttctttttcggcaacatc
acccgggaggaggcagaagattacctggtccaggggggcatgagcgatgggctctatttg
ctgcgccagagccgcaactacctgggcggcttcgccctgtccgtggcgcacgggaggaag
gcacaccactacaccatcgagcgggagctgaacggcacctatgccatcgccggcggcagg
acccacgccagccccgccgacctctgccactaccactcgcaggagtctgatggcctggtc
tgcctcctcaagaagcccttcaaccggccgcagggggtgcagcccaagactgggcccttt
gaggacttgaaggaaaacctcatcagggaatatgtgaagcagacatggaacctgcagggt
caggctctggagcaggccatcatcagccagaagcctcagctggagaagctgatcgccacc
acagcccatgaaaaaatgccttggttccatggaaaaatctctcgagaagagtctgagcaa
attgtcctgataggatcaaagacaaacggaaagttcctgatccgagccagagacaacaac
ggctcctacgccctgtgcttgctgcacgaagggaaggtgctgcactatcgcattgacaaa
gacaagacagggaagctctccatccccgagggaaagaagttcgacacgctctggcagctc
gtcgagcattattcttataaagcagatggtttgttaagagttcttactgtcccgtgtcaa
aaaatcggcacacagggaaatgttaattttggaggtcgtccacaacttccaggttcccat
cctgcgacttggtcagcgggtggaataatctcaagaatcaaatcatactccttcccaaag
cctggccacagaaagccctcccctgcccaagggaaccggccagagagtactgtgtcattc
aatccgtatgagccagaagttgcaccctgggctgcagaaaaaggcccccagagagaagcc
ctacccatggacacagaggtgtatgagagcccctatgcggaccctgaggagatcaggccc
aaggaggtttacctggaccgaaagctgctgacgctggaagacaaagaactgggctctggt
aattttggaactgtgaaaaagggctactaccaaatgaaaaaagttgtgaaaacagtggct
gtgaaaattctgaaaaacgaggccaatgaccccgctcttaaagatgagttattagcagaa
gcaaatgtcatgcagcagctggacaacccgtatatcgtgcgcatgatcgggatatgcgag
gccgagtcctggatgctggttatggagatggcagaacttggtcccctcaataagtatttg
cagcagaacagacatgtcaaggataagaacatcatagaactggttcatcaggtttccatg
ggcatgaagtatctggaggagtgcaattttgtgcacagagatctggccgcaagaaatgtg
ttgctagttactcaacattatgccaagatcagtgatttcggactttccaaagcactgcgt
gctgatgaaaactactacaaggcccagacccatggaaagtggcctgtcaagtggtacgct
ccggaatgcatcaactactacaagttctccagcaaaagcgatgtctggagctttggagtg
ttgatgtgggaagcattctcctacgggcagaagccgtatcgagggatgaaaggaagtgaa
gtcaccgctatgttagaaaaaggagagcggatggggtgccctgcaggatgtccaagagag
atgtacgatctcatgaacctgtgctggacgtacgatgtggagaacaggcccggattcgca
gcagtggaactgcgtctgcgcaattactactatgacgtggtgaactaa

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