Macaca mulatta (rhesus monkey): 704683
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Entry
704683 CDS
T01028
Gene name
IKBKB
Definition
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit beta
KO
K07209
inhibitor of nuclear factor kappa-B kinase subunit beta [EC:
2.7.11.10
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc01523
Antifolate resistance
mcc04010
MAPK signaling pathway
mcc04014
Ras signaling pathway
mcc04062
Chemokine signaling pathway
mcc04064
NF-kappa B signaling pathway
mcc04068
FoxO signaling pathway
mcc04150
mTOR signaling pathway
mcc04151
PI3K-Akt signaling pathway
mcc04210
Apoptosis
mcc04380
Osteoclast differentiation
mcc04620
Toll-like receptor signaling pathway
mcc04621
NOD-like receptor signaling pathway
mcc04622
RIG-I-like receptor signaling pathway
mcc04623
Cytosolic DNA-sensing pathway
mcc04625
C-type lectin receptor signaling pathway
mcc04657
IL-17 signaling pathway
mcc04658
Th1 and Th2 cell differentiation
mcc04659
Th17 cell differentiation
mcc04660
T cell receptor signaling pathway
mcc04662
B cell receptor signaling pathway
mcc04668
TNF signaling pathway
mcc04722
Neurotrophin signaling pathway
mcc04910
Insulin signaling pathway
mcc04920
Adipocytokine signaling pathway
mcc04930
Type II diabetes mellitus
mcc04931
Insulin resistance
mcc04932
Non-alcoholic fatty liver disease
mcc05010
Alzheimer disease
mcc05132
Salmonella infection
mcc05135
Yersinia infection
mcc05142
Chagas disease
mcc05145
Toxoplasmosis
mcc05160
Hepatitis C
mcc05161
Hepatitis B
mcc05162
Measles
mcc05163
Human cytomegalovirus infection
mcc05164
Influenza A
mcc05165
Human papillomavirus infection
mcc05166
Human T-cell leukemia virus 1 infection
mcc05167
Kaposi sarcoma-associated herpesvirus infection
mcc05168
Herpes simplex virus 1 infection
mcc05169
Epstein-Barr virus infection
mcc05170
Human immunodeficiency virus 1 infection
mcc05171
Coronavirus disease - COVID-19
mcc05200
Pathways in cancer
mcc05206
MicroRNAs in cancer
mcc05212
Pancreatic cancer
mcc05215
Prostate cancer
mcc05220
Chronic myeloid leukemia
mcc05221
Acute myeloid leukemia
mcc05222
Small cell lung cancer
mcc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mcc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
704683 (IKBKB)
04014 Ras signaling pathway
704683 (IKBKB)
04064 NF-kappa B signaling pathway
704683 (IKBKB)
04668 TNF signaling pathway
704683 (IKBKB)
04068 FoxO signaling pathway
704683 (IKBKB)
04151 PI3K-Akt signaling pathway
704683 (IKBKB)
04150 mTOR signaling pathway
704683 (IKBKB)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
704683 (IKBKB)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
704683 (IKBKB)
04621 NOD-like receptor signaling pathway
704683 (IKBKB)
04622 RIG-I-like receptor signaling pathway
704683 (IKBKB)
04623 Cytosolic DNA-sensing pathway
704683 (IKBKB)
04625 C-type lectin receptor signaling pathway
704683 (IKBKB)
04660 T cell receptor signaling pathway
704683 (IKBKB)
04658 Th1 and Th2 cell differentiation
704683 (IKBKB)
04659 Th17 cell differentiation
704683 (IKBKB)
04657 IL-17 signaling pathway
704683 (IKBKB)
04662 B cell receptor signaling pathway
704683 (IKBKB)
04062 Chemokine signaling pathway
704683 (IKBKB)
09152 Endocrine system
04910 Insulin signaling pathway
704683 (IKBKB)
04920 Adipocytokine signaling pathway
704683 (IKBKB)
09156 Nervous system
04722 Neurotrophin signaling pathway
704683 (IKBKB)
09158 Development and regeneration
04380 Osteoclast differentiation
704683 (IKBKB)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
704683 (IKBKB)
05206 MicroRNAs in cancer
704683 (IKBKB)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
704683 (IKBKB)
09162 Cancer: specific types
05212 Pancreatic cancer
704683 (IKBKB)
05221 Acute myeloid leukemia
704683 (IKBKB)
05220 Chronic myeloid leukemia
704683 (IKBKB)
05215 Prostate cancer
704683 (IKBKB)
05222 Small cell lung cancer
704683 (IKBKB)
09164 Neurodegenerative disease
05010 Alzheimer disease
704683 (IKBKB)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
704683 (IKBKB)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
704683 (IKBKB)
04932 Non-alcoholic fatty liver disease
704683 (IKBKB)
04931 Insulin resistance
704683 (IKBKB)
09171 Infectious disease: bacterial
05132 Salmonella infection
704683 (IKBKB)
05135 Yersinia infection
704683 (IKBKB)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
704683 (IKBKB)
05170 Human immunodeficiency virus 1 infection
704683 (IKBKB)
05161 Hepatitis B
704683 (IKBKB)
05160 Hepatitis C
704683 (IKBKB)
05171 Coronavirus disease - COVID-19
704683 (IKBKB)
05164 Influenza A
704683 (IKBKB)
05162 Measles
704683 (IKBKB)
05168 Herpes simplex virus 1 infection
704683 (IKBKB)
05163 Human cytomegalovirus infection
704683 (IKBKB)
05167 Kaposi sarcoma-associated herpesvirus infection
704683 (IKBKB)
05169 Epstein-Barr virus infection
704683 (IKBKB)
05165 Human papillomavirus infection
704683 (IKBKB)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
704683 (IKBKB)
05142 Chagas disease
704683 (IKBKB)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
704683 (IKBKB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
704683 (IKBKB)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
704683 (IKBKB)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: Other
IKK family [OT]
704683 (IKBKB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IKBKB_SDD
Pkinase
PK_Tyr_Ser-Thr
IKKbetaNEMObind
Pkinase_fungal
Kdo
ubiquitin
APH
YrbL-PhoP_reg
Med20
Glyco_hydro_65m
Motif
Other DBs
NCBI-GeneID:
704683
NCBI-ProteinID:
NP_001252875
Ensembl:
ENSMMUG00000008351
UniProt:
F6SHC1
G7MZ74
LinkDB
All DBs
Position
8
AA seq
756 aa
AA seq
DB search
MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCL
EIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREG
AILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCT
SFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSE
VDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPKYGPNGCF
KALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLA
LIPDKPATQCISDGKLNEGRTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRN
LAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLK
AKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMAL
QTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQS
FEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKI
ACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLE
NAIQDTVREQDQSFTALDWSWLQTEEEEHSCLEQAS
NT seq
2271 nt
NT seq
+upstream
nt +downstream
nt
atgagctggtcaccttccctgacaacccagacatgtggggcctgggaaatgaaagagcgc
cttgggacagggggatttggaaatgtcatccgatggcacaatcaggaaacaggtgagcag
attgccatcaagcagtgccggcaggagctcagcccccggaatcgagagcggtggtgcctg
gagatccagatcatgagaaggctgacgcaccccaatgtggtggctgcccgagatgtccct
gaggggatgcagaacttggcgcccaatgacttgcccctgctggccatggagtattgccaa
ggaggagatctccggaagtacctgaaccagtttgagaattgctgtggtctgcgggaaggt
gccatcctcaccttgctgagtgacattgcctctgcacttagataccttcatgaaaacaga
atcatccatcgggatctaaagccagaaaacatcgtcctgcagcaaggagaacagaggtta
atacacaaaattattgacctaggatatgccaaggagctggatcagggcagtctttgcacg
tcattcgtggggaccctgcagtacctggccccagagctgctggagcagcagaagtacaca
gtgaccgtcgactactggagctttggcaccctggccttcgagtgcatcacgggcttccgg
cccttcctccccaactggcagcccgtgcagtggcattcgaaagtccggcagaagagtgag
gtggatattgttgtcagcgaagacttgaatggaacagtgaagttttcaagctctttaccc
taccccaataatcttaacagcgtcctggctgagcgactggagaagtggctgcaactgatg
ctgatgtggcatccccgacagaggggcacagatcccaagtatgggcccaatggctgcttc
aaggccctggatgacatcttaaacttaaagctggttcatatcttgaacatggtcacaggc
accatccacacctaccctgtgacagaggacgagagtctgcagagcttgaaggccagaatc
cagcaggacacgggcatcccagaggaggaccaggagctgctgcaggaagcgggcctggcg
ttgatccccgataaacctgccactcagtgtatttcagatggcaagttaaatgagggccgc
acattggacatggatcttgtttttctctttgacaacagtaaaatcacctatgagactcag
atctccccacggccccaacctgaaagtgtcagctgtatccttcaagagcccaagaggaac
ctcgccttcttccagctgaggaaggtgtggggccaggtctggcacagcatccagacccta
aaggaggattgcaaccggctgcagcagggacagcgagccgccatgatgaatctcctccgg
aacaacagctgcctctccaagatgaagaattccatggcttccatgtctcagcagctcaag
gccaagttggatttcttcaaaaccagcatccagattgacctggagaagtacagcgagcaa
actgagtttgggatcacatcagataaactgctgctggcctggagggaaatggagcaggcc
gtggagctctgtgggcgggagaacgaagtgaaactcctggtagaacggatgatggctctg
cagacggacatcgtggacttacagaggagccccatgggccggaagcaggggggaacattg
gacgacctagaggagcaagcaagggagctgtacaggagactaagggaaaagcctcgagac
cagcgaactgagggtgacagtcaggaaatggtacggctgctgcttcaggcaattcagagc
ttcgagaagaaagtgcgagtgatctatacacagctcagtaaaactgtggtttgcaagcag
aaggcgctggaactgttgcccaaggtggaagaggtggtgagcttaatgaatgaggatgag
aagactgttgtccggctgcaggagaagcggcagaaggagctctggaatctcctgaagatt
gcttgtagcaaggtccgtggtcctgtcagtggaagcccggatagcatgaatgcctctcga
cttagccagcctgggcagctgatgtctcagccctccacggcctccaacagcttacccgaa
ccagccaagaagagtgaagaactggtggccgaagcacataacctgtgcaccctgctagaa
aatgccatacaggacaccgtgagggagcaagaccagagtttcacggccctagactggagc
tggttacagacggaagaagaagagcacagctgcctggagcaggcctcctga
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integrated database retrieval system
