Macaca mulatta (rhesus monkey): 704823
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Entry
704823 CDS
T01028
Gene name
ALK
Definition
(RefSeq) ALK tyrosine kinase receptor isoform X1
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc05200
Pathways in cancer
mcc05223
Non-small cell lung cancer
mcc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
704823 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
704823 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
704823 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
704823 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mcc04090
]
704823 (ALK)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
704823 (ALK)
Protein kinases [BR:
mcc01001
]
Receptor tyrosine kinases (RTK)
ALK family
704823 (ALK)
CD molecules [BR:
mcc04090
]
Proteins
704823 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
MAM
Gly_rich
Ldl_recept_a
Nup96
Motif
Other DBs
NCBI-GeneID:
704823
NCBI-ProteinID:
XP_014967517
LinkDB
All DBs
Position
13
AA seq
1620 aa
AA seq
DB search
MGTIGLLWLLPLLLSTAALGSGTGTGQRTGSPAAGPPLQPREPLSYSRLQRKSLAVDFVV
PSLFRVYARDLLLPPSPSELKAGRPEARGSLALDCAPLLRLLGPAPGVSWTAGSPTPAEA
RTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPGEAAVGLLQFNLSELFSWWIRQ
GEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLFQIFGTGHSSLESPTNIPSPSPDY
FTWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWRRVPSEEASQ
MDLLDGPEAERSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGR
YIAQLLPHNEAAREILLMPTPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFF
ALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQDCAQGEDESQICRKLPVGFYC
NFEDGFCGWTQGTLSPHTPQWQVRTLKDARFQDHQDHALLLSTTDAPTSESATVTSATFP
APIKSSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWTVLPL
LDVSDRFWLQMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKILQNTAPKSRNLFERNP
NKELKPGENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPL
KGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDTLYILVGQQGE
DACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLII
AAGGGGRAYGAKTDAFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSLLEGA
TGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGVSFIS
PLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVS
CIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKL
SKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGVPN
DPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMA
GGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKRGEERSPAA
PPPVPTTSSGKAAKKPTAAEVSVRVPRGPAVEGGHVNMAFSQSNPPSELHKVQGSRNKPT
SLWNPTYGSWFTEKPTKKNNPLAKKEPHERGNLGLEGSCTVPPNVATGRLPGASLLLEPS
SLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atgggaaccatcgggctcctgtggctgctgccgctgctgctttccactgcagctttgggc
tctgggacggggaccggccagcgcacgggatccccagctgcggggccgccgctgcagccc
cgggagccgctcagctactctcgcctgcagaggaagagtctggcagtggacttcgtagtg
ccctcactcttccgtgtctatgcccgggacctgctgctgccgccatccccctcggagctg
aaggctggcaggcccgaggcgcgaggctcgctcgctctggactgcgccccgctgctcagg
ttgctggggccggcgcctggggtctcctggacagccggctcacccaccccggcagaggcc
cggacgctgtccagggtgctgaagggcggctcggtgcgcaagctccggcgtgccaagcag
ctggtgctggagctgggcgaggaggcgatcttggagggttgcgtcgggccccctggggag
gcggctgtggggctgctccagttcaacctcagcgagctgttcagttggtggattcgccag
ggcgaagggcgactgaggatccgcctgatgcccgagaagaaggcgtcggaagtgggcaga
gagggaaggctgtccgcggcaatccgcgcctcccagccccgccttctcttccagatcttc
gggactggtcatagctccttggagtcaccaacaaacataccttctccttctcctgattat
tttacatggaatctcacctggataatgaaagactccttccctttcctgtctcatcgcagc
cgatatggtctggagtgcagctttgacttcccctgtgagctggaatattcccctccactg
cacgacctcaggaaccagagctggtcctggcgccgtgttccctccgaggaggcctcccag
atggacttgctggatgggcctgaggcagagcgttctaaggagatgcccagagggtccttt
ctcctcctcaacacctcagctgactccaagcacaccatcctaagtccgtggatgaggagc
agcagtgagcactgtacgctggccgtctcagtgcacaggcacctgcagccctctggaagg
tacattgcccagctgctgccccacaacgaggctgcaagagagatcctcctgatgcccacc
ccagggaagcatggttggacagtgctccagggaagaatcgggcgcccagacaaccccttt
cgagtggccctggaatacatctccagtggaaaccgcagcttgtctgcagtggacttcttt
gccctgaagaactgcagtgaaggaacatccccaggctccaagatggccctgcagagctcc
ttcacttgttggaatgggacagtcctccagcttgggcaggcctgtgacttccaccaggac
tgcgcccagggagaagacgagagccagatatgccggaaactccctgtgggtttttactgc
aacttcgaagatggcttctgtggctggacccaaggcacactctcacctcacactcctcag
tggcaggtcaggactctaaaggatgcccggttccaggaccaccaagaccatgctctattg
ctcagtaccactgatgcccccacttcagaaagtgctacagtgaccagtgctacgtttccc
gcaccgatcaagagctctccatgtgagctccgaatgtcctggctcattcgtggagtcctg
aggggaaacgtgtccttggtgctagtggagaacaaaactgggaaggagcaaggcaggatg
gtctggcatgtcgccgcctatgaaggcttgagcctgtggcagtggacggtgttgcctctc
ctcgacgtgtctgacaggttctggctgcagatggttgcatggtggggacaaggatccaga
gccatcgtggcttttgacaatatttccatcagcctggactgctacctcaccattagtgga
gaggacaagatcctacagaatacagcacccaaatcaagaaacctgtttgagagaaaccca
aacaaggagctgaaacccggggaaaattcaccacgacagacgcccatctttgaccctaca
gttcattggctgttcaccacatgtggggccagcggaccccatggtcccacccaggcgcag
tgcaacaacgcctaccagaactccaacctgagcgtggaggtgggaagcgagggccccctg
aagggcatccagatctggaaggtgccagccaccgacacctacagcatctcgggctacgga
gctgctggcgggaaaggcgggaagaacaccatgatgcggtcccacggcgtgtctgtgctg
ggcatcttcaacctggagaaagacgacacgctgtacatcctggttgggcagcagggagag
gacgcctgccccagtacaaaccagttaatccagaaagtctgcattggagagaacaatgtg
atagaagaagaaatccgtgtgaacagaagcgtgcatgagtgggcaggaggaggaggagga
gggggtggagccacctatgtatttaagatgaaggatggagtgccggtgcccctgatcatt
gcagccggaggtggcggcagggcctatggggccaagacagacgcgttccacccagagaga
ctggagaataactcctcggttctagggctgaacggcaattccggagccgcaggtggtgga
ggtggctggaatgataacacttccttgctctgggccggaaaatctttgctggagggtgcc
accggaggacattcctgcccccaggccatgaagaagtgggggtgggagacaagagggggt
ttcggagggggtggaggggggtgctcctcaggtggaggaggcggaggatatataggcggc
aatgcagcctcaaacaatgaccccgaaatggatggggaagatggggtttccttcatcagt
ccactgggcatcctgtacaccccagctttaaaagtgatggaaggccatggggaagtgaat
attaagcattatctaaactgcagtcactgtgaggtagacgaatgtcacatggacactgaa
agccacaaggtcatctgcttctgtgaccacgggacagtgctggcagaggatggcgtctcc
tgcattgtgtcgcccaccccggagccgcacctgccactctcactgatcctctccgtggtg
acctctgccctcgtggctgccctggtcctggctttctccggcatcatgattgtgtaccgc
cggaagcaccaggagctgcaagccatgcagatggagctgcagagccctgagtacaagctg
agtaagctccgcacctcaaccatcatgaccgactacaaccccaactactgctttgctggc
aagacctcctccatcagtgacctgaaggaggtgccgcggaaaaacatcaccctcattcgg
ggtctgggccatggcgcctttggggaggtgtatgaaggccaggtgtccggagtgcccaac
gacccaagccccctgcaagtggctgtgaagacgctgcctgaggtgtgctcagaacaggac
gaactggatttcctcatggaagccctgatcatcagcaaattcaaccaccagaacatcgtt
cgctgcatcggggtgagcctgcaggccctgccccggttcatcctactggagctcatggca
ggaggagacctcaagtccttcctccgagagacccgccctcgcccgagccagccctcctcc
ctggccatgctggaccttctgcatgtggctcgggacattgcctgtggctgtcagtatttg
gaggaaaaccacttcatccaccgagacattgctgccagaaactgcctcttgacctgtcca
ggccctggaagagtggccaagattggagacttcgggatggcccgagacatctacagggcg
agctactacagaaagggaggctgtgcgatgctgccagttaagtggatgcccccagaggcc
ttcatggaaggaatattcacctctaaaacagacacatggtcctttggagtgctgctgtgg
gaaatcttttctctcggatatatgccatatcccagcaaaagcaaccaggaagttctggag
ttcgtcaccagtggaggccggatggacccacccaagaactgccctgggcctgtataccgg
ataatgactcagtgctggcaacatcagcctgaagacaggcccaactttgccatcattttg
gagaggattgaatactgcacccaggacccagatgtaatcaacactgctttgccgatagaa
tacggtccacttgtagaagaggaagagaaagtacccgtgaggcccaaggaccctgagggg
gttcctcctctcctggtctctcaacaggcgaaacggggggaggagcgcagcccagctgcc
ccaccacctgtgcctaccacctcctctggcaaggctgcaaagaaacccacagctgcagag
gtctctgttcgagtccctagagggccggccgtggaagggggacacgtgaatatggcattc
tctcagtccaaccccccttcggagttgcacaaggtccagggatccagaaacaagcccacc
agcttgtggaacccaacgtacggctcctggtttacagagaaacccaccaaaaagaataat
cctctagcaaagaaggagccacatgagagaggtaacctagggctggagggaagctgtact
gtcccacctaacgttgcaactgggagacttccgggggcctcactgctcctagagccctct
tcgctgactgccaacatgaaggaggtacctctgttcaggctacgtcacttcccttgtggg
aatgtcaattacggctaccagcaacagggcttgcccttagaagccgctactgcccccgga
gctggtcattacgaggacaccattctgaaaagcaagaatagcatgaaccagcctgggccc
tga
Macaca mulatta (rhesus monkey): 715091
Help
Entry
715091 CDS
T01028
Gene name
EML4
Definition
(RefSeq) echinoderm microtubule-associated protein-like 4 isoform X1
KO
K15420
echinoderm microtubule-associated protein-like 4
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc05200
Pathways in cancer
mcc05223
Non-small cell lung cancer
mcc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
715091 (EML4)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
715091 (EML4)
09162 Cancer: specific types
05223 Non-small cell lung cancer
715091 (EML4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
mcc04812
]
715091 (EML4)
Cytoskeleton proteins [BR:
mcc04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EMAP
715091 (EML4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
WD40
HELP
ANAPC4_WD40
SlyX
Ribosomal_S7
Motif
Other DBs
NCBI-GeneID:
715091
NCBI-ProteinID:
XP_014967716
Ensembl:
ENSMMUG00000016277
LinkDB
All DBs
Position
13
AA seq
991 aa
AA seq
DB search
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVA
SVKKSVSSKGQPSPRAAIPMSCITNGSGANRKPSHTSTVSIAGKETLSSAAKSGTEKKKE
KPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKNTDKHKDVIINQAKMSTREKNSQEGEYIKM
FMRGRPITMFIPSDVDNYDDIRTELPSEKLKLEWAYGYRGKDCRANVYLLPTGEIVYFIA
SVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSV
TLSTLQIIGLGTFERGVGCLDFSKADSGVHLCVIDDSNEHMLTVWDWQKKAKGAEIKTTN
EVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGD
VLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGK
DRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGAFNDGFQIEVQ
GHTDELWGLATHPFKDLLLTCAQDRQVCLWNSMEHRLEWTRLVDEPGHCADFHPSGTVVA
IGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGR
KYSRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWT
TYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKAKAPSHK
YSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLSLPQNETVADTTLTKAPVSST
ESVIQSDTPTPPPSQSLNETAEEESRISSSPTLLENSLEQTVEPSEDHSEEESEGGSGDL
GEPLYEEPSNEISKQGEATLPEDQQDPLPSS
NT seq
2976 nt
NT seq
+upstream
nt +downstream
nt
atggacggtttcgccggcagcctcgatgatagtatttctgctgcaagtacttctgatgtt
caagatcgcctgtcagctcttgagtcacgagttcagcaacaagaagacgaaatcactgtg
ctgaaggcagctttggctgatgttttgaggcgtcttgcaatctctgaagatcatgtggcc
tcagtgaaaaaatcagtctcaagtaaaggccaaccaagccctcgagcagctattcccatg
tcctgtataaccaatggaagtggtgcaaacagaaaaccaagtcataccagcactgtctca
attgcaggaaaagaaactctttcatctgctgctaaaagtggtacagaaaaaaagaaagaa
aaaccacaaggacagagagaaaaaaaagaggaatctcattctaatgatcaaagtccacaa
attcgagcatcaccttctccccagccctcttcacaacctctccaaatacacagacaaact
ccagaaagcaagaatgctactcccaccaaaagcataaaacgaccatcaccagctgaaaag
tcacacaattcatgggaaaattcagatgatagccgtaataaattgtcgaaaataccttca
acacccaaattaataccaaaagttaccaaaaatacagacaagcataaagatgtcatcatc
aaccaagcaaaaatgtcaactcgtgaaaaaaacagccaagaaggagaatatattaaaatg
tttatgcgcggtcggccaattaccatgttcattccttctgatgttgacaactatgatgac
atcagaacagaactgccttctgagaagctcaaactggagtgggcatatggttatcgagga
aaggactgtagagctaatgtttaccttcttccgaccggggaaatagtttatttcattgca
tcagtggtagtactatttaattatgaggagagaactcaacgacactatctgggtcataca
gactgtgtgaaatgccttgctatacatcctgacaaaattaggattgcaactggacagata
gctggcgtggataaagatggaaggcctctacaaccccacgtcagagtgtgggattctgtt
actctctccacactgcagattattggacttggcacttttgagcgtggagtaggatgcctg
gatttttcaaaagcagattcaggtgttcatttatgtgttattgatgactccaatgaacat
atgcttactgtatgggactggcagaaaaaagcaaaaggagcagaaataaagacaacaaat
gaagttgttttggctgtggagtttcacccaacagatgcaaataccataattacgtgcggt
aaatctcatattttcttctggacctggagtggcaattcactaacaagaaaacagggaatt
tttgggaaatatgaaaagccaaaatttgtgcagtgtttagcattcttggggaatggagat
gttcttactggagactcaggtggagtcatgcttatatggagcaaaactactgtagagccc
acacctgggaaaggacctaaaggtgtatatcaaatcagcaaacaaatcaaagctcatgat
ggcagtgtgttcacactttgtcagatgagaaatgggatgttattaactggaggagggaaa
gacagaaaaataattctgtgggatcacgatctgaatcctgaaagagaaatagaggttcct
gatcagtatggcacaatcagagctgtagcagaaggaaaggcagatcaatttttagtaggc
acatcacgaaactttattttacggggagcatttaatgatggcttccaaatagaagtacag
ggtcatacagatgagctttggggtcttgctacacatcccttcaaagatttgctcttgaca
tgtgctcaggacaggcaggtgtgcctgtggaactcaatggaacacaggctggaatggacc
aggctggtagatgaaccaggacactgtgcagattttcatccaagtggcacagtggtggcc
ataggaacgcactcaggcaggtggtttgttctggatgcagaaaccagagatctagtttct
atccacacagacgggaatgaacagctctctgtgatgcgctactcaatagatggtaccttc
ctggctgtaggatctcatgacaactttatttacctctatgtagtctctgaaaatggaaga
aaatatagcagatatggaaggtgcactggacattccagctacatcacacaccttgactgg
tccccagacaacaagtatataatgtctaactcgggagactatgaaatattgtactgggac
attccaaatggctgcaaactaatcaggaatcgatcggattgtaaggacattgattggacg
acatatacctgtgtgctaggatttcaagtctttggtgtctggccagaaggatctgatggg
acagatatcaatgccctggtgcgatcccacaatagaaaggtgatagctgttgccgatgac
ttttgtaaagtccatctgtttcagtatccctgctccaaagcaaaggctcccagccacaag
tacagtgcccacagcagccatgtcaccaacgtcagttttacacacaacgacagtcacctg
atatcaactggtggaaaagacatgagcatcattcagtggaaacttgtggaaaagttatct
ttgcctcagaatgagactgtagcggatactactctaaccaaagcccccgtctcttccact
gaaagtgtcatccaatctgatactcccacaccgcctccttctcagtccttaaatgagaca
gctgaagaggaaagtagaataagcagttctcccacacttctggagaacagcctggaacaa
actgtggagccaagcgaagaccacagcgaggaggagagtgaagggggcagcggagacctt
ggtgagcctctttatgaagagccatccaatgagataagcaagcagggcgaagccaccctt
ccagaggaccagcaagaccctttgccctcgtcctaa
DBGET
integrated database retrieval system
