Macaca mulatta (rhesus monkey): 709511
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Entry
709511 CDS
T01028
Gene name
CHUK
Definition
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3
KO
K04467
inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:
2.7.11.10
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc01523
Antifolate resistance
mcc04010
MAPK signaling pathway
mcc04014
Ras signaling pathway
mcc04062
Chemokine signaling pathway
mcc04064
NF-kappa B signaling pathway
mcc04068
FoxO signaling pathway
mcc04150
mTOR signaling pathway
mcc04151
PI3K-Akt signaling pathway
mcc04210
Apoptosis
mcc04380
Osteoclast differentiation
mcc04620
Toll-like receptor signaling pathway
mcc04621
NOD-like receptor signaling pathway
mcc04622
RIG-I-like receptor signaling pathway
mcc04623
Cytosolic DNA-sensing pathway
mcc04625
C-type lectin receptor signaling pathway
mcc04657
IL-17 signaling pathway
mcc04658
Th1 and Th2 cell differentiation
mcc04659
Th17 cell differentiation
mcc04660
T cell receptor signaling pathway
mcc04662
B cell receptor signaling pathway
mcc04668
TNF signaling pathway
mcc04920
Adipocytokine signaling pathway
mcc05010
Alzheimer disease
mcc05132
Salmonella infection
mcc05135
Yersinia infection
mcc05142
Chagas disease
mcc05145
Toxoplasmosis
mcc05160
Hepatitis C
mcc05161
Hepatitis B
mcc05162
Measles
mcc05163
Human cytomegalovirus infection
mcc05164
Influenza A
mcc05165
Human papillomavirus infection
mcc05166
Human T-cell leukemia virus 1 infection
mcc05167
Kaposi sarcoma-associated herpesvirus infection
mcc05168
Herpes simplex virus 1 infection
mcc05169
Epstein-Barr virus infection
mcc05170
Human immunodeficiency virus 1 infection
mcc05171
Coronavirus disease - COVID-19
mcc05200
Pathways in cancer
mcc05212
Pancreatic cancer
mcc05215
Prostate cancer
mcc05220
Chronic myeloid leukemia
mcc05221
Acute myeloid leukemia
mcc05222
Small cell lung cancer
mcc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mcc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
709511 (CHUK)
04014 Ras signaling pathway
709511 (CHUK)
04064 NF-kappa B signaling pathway
709511 (CHUK)
04668 TNF signaling pathway
709511 (CHUK)
04068 FoxO signaling pathway
709511 (CHUK)
04151 PI3K-Akt signaling pathway
709511 (CHUK)
04150 mTOR signaling pathway
709511 (CHUK)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
709511 (CHUK)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
709511 (CHUK)
04621 NOD-like receptor signaling pathway
709511 (CHUK)
04622 RIG-I-like receptor signaling pathway
709511 (CHUK)
04623 Cytosolic DNA-sensing pathway
709511 (CHUK)
04625 C-type lectin receptor signaling pathway
709511 (CHUK)
04660 T cell receptor signaling pathway
709511 (CHUK)
04658 Th1 and Th2 cell differentiation
709511 (CHUK)
04659 Th17 cell differentiation
709511 (CHUK)
04657 IL-17 signaling pathway
709511 (CHUK)
04662 B cell receptor signaling pathway
709511 (CHUK)
04062 Chemokine signaling pathway
709511 (CHUK)
09152 Endocrine system
04920 Adipocytokine signaling pathway
709511 (CHUK)
09158 Development and regeneration
04380 Osteoclast differentiation
709511 (CHUK)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
709511 (CHUK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
709511 (CHUK)
09162 Cancer: specific types
05212 Pancreatic cancer
709511 (CHUK)
05221 Acute myeloid leukemia
709511 (CHUK)
05220 Chronic myeloid leukemia
709511 (CHUK)
05215 Prostate cancer
709511 (CHUK)
05222 Small cell lung cancer
709511 (CHUK)
09164 Neurodegenerative disease
05010 Alzheimer disease
709511 (CHUK)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
709511 (CHUK)
09171 Infectious disease: bacterial
05132 Salmonella infection
709511 (CHUK)
05135 Yersinia infection
709511 (CHUK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
709511 (CHUK)
05170 Human immunodeficiency virus 1 infection
709511 (CHUK)
05161 Hepatitis B
709511 (CHUK)
05160 Hepatitis C
709511 (CHUK)
05171 Coronavirus disease - COVID-19
709511 (CHUK)
05164 Influenza A
709511 (CHUK)
05162 Measles
709511 (CHUK)
05168 Herpes simplex virus 1 infection
709511 (CHUK)
05163 Human cytomegalovirus infection
709511 (CHUK)
05167 Kaposi sarcoma-associated herpesvirus infection
709511 (CHUK)
05169 Epstein-Barr virus infection
709511 (CHUK)
05165 Human papillomavirus infection
709511 (CHUK)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
709511 (CHUK)
05142 Chagas disease
709511 (CHUK)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
709511 (CHUK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
709511 (CHUK)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
709511 (CHUK)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: Other
IKK family [OT]
709511 (CHUK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IKBKB_SDD
Pkinase
PK_Tyr_Ser-Thr
IKKbetaNEMObind
Pkinase_fungal
Kdo
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
709511
NCBI-ProteinID:
XP_001107171
Ensembl:
ENSMMUG00000018476
UniProt:
G7N0X0
A0A1D5Q734
LinkDB
All DBs
Position
9
AA seq
745 aa
AA seq
DB search
MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCH
EIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQ
ILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTS
FVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK
CIFACEEMSGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRC
FVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGI
SLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPI
VQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKL
EFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAE
IMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRV
LKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQ
SSARSLVGSSLEGAVTPQTSVWLPPTSAEHDHSLSCVVTPQDGDTSAQMIEENLNCLGHL
STIIHEANEEQGNSMMNLDWSWLTE
NT seq
2238 nt
NT seq
+upstream
nt +downstream
nt
atggagcggcccccggggctgcggccgggcgcgggcgggccctgggagatgcgggagcgg
ttgggcaccggcggcttcgggaacgtctgtctgtaccagcatcgggaacttgatctcaaa
atagcaattaagtcttgtcgcctagagctaagtaccaaaaacagagaacgatggtgccac
gaaatccagattatgaagaagttgaaccatgccaacgttgtaaaggcctgtgatgttcct
gaagaattgaatattttgattcatgatgtgcctcttctagcaatggaatactgttctgga
ggagatctccgaaagctgctcaacaaaccagaaaattgttgtggacttaaagaaagccag
atactttctttactaagtgatatagggtctgggattcgatatttgcatgaaaacaaaatt
atacatcgagatctaaaacctgaaaacatagttcttcaggacgttggtggaaagataata
cataaaataattgatctgggatatgccaaagatgttgatcaaggaagtctgtgtacatct
tttgtgggaacactgcagtatctggccccagagctctttgagaataagccttacacagcc
actgttgattattggagctttgggaccatggtatttgaatgtattgctggatataggcct
tttttgcatcatctgcagccatttacctggcatgagaagattaagaagaaggatccaaag
tgtatatttgcatgtgaagagatgtcaggagaagttcggtttagtagccatttacctcaa
ccaaatagcctttgtagtttaatagtagaacccatggaaaactggctacagttgatgttg
aattgggaccctcagcagagaggaggacctgttgaccttactttgaagcagccaagatgt
tttgtactaatggatcacattttgaatttgaagatagtacacatcctaaatatgacttct
gcaaagataatttcttttctgttaccacctgatgaaagtcttcattcactacagtctcgt
attgagcgtgaaactggaataaatactggttctcaagaacttctttcagagacaggaatt
tctctggatcctcggaaaccagcctctcaatgtgttctagatggagttagaggctgtgat
agctatatggtttatttgtttgataaaagtaaaactgtgtatgaagggccatttgcttcc
agaagtttatctgattgtgtaaattatattgtacaggacagcaaaatacagcttccaatt
gtacagctgcgtaaagtgtgggctgaagcagtgcactatgtgtctggactaaaagaagac
tacagcaggctctttcagggacaaagggcagcaatgttaagtcttcttagatataatgct
aacttaacaaaaatgaagaacactttgatctcagcatcacaacaactgaaagctaaattg
gagttttttcacaaaagcattcagcttgacttggagagatacagcgagcagatgacgtat
gggatatcttcagaaaaaatgctaaaagcatggaaagaaatggaagaaaaggccatccac
tatgctgaggttggtgtcattggatacctggaggatcagattatgtctttgcatgctgaa
atcatggagctacagaagagcccctatggaagacgtcagggagacttgatggaatctctg
gaacagcgtgctattgatctatataagcagttaaaacacagaccttcagatcactcctac
agtgacagcacagagatggtgaaaatcattgtgcacactgtgcagagtcaggaccgtgtg
ctcaaggagctgtttggtcatttgagcaagttgttgggctgtaagcagaagattattgat
ctactccctaaggtggaagtggccctcagtaacatcaaagaagctgataatactgtcatg
ttcatgcagggaaaaaggcagaaagaaatatggcatctccttaaaattgcctgtacacag
agttctgcccggtcccttgtaggatccagtctagaaggtgcagtaacccctcagacgtca
gtatggctgcccccgacttcagcagaacatgatcattctctgtcatgtgtggtaactcct
caagatggggatacttcagcacaaatgatagaagaaaatttgaactgccttggccattta
agcactattattcatgaggcaaatgaggaacagggcaatagtatgatgaatcttgattgg
agttggttaacagaatga
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integrated database retrieval system
