Macaca mulatta (rhesus monkey): 710441 Help Entry 710441            CDS       T01028                                  Gene name SPHK1 Definition (RefSeq) sphingosine kinase 1 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc00600   Sphingolipid metabolism mcc01100   Metabolic pathways mcc04020   Calcium signaling pathway mcc04071   Sphingolipid signaling pathway mcc04072   Phospholipase D signaling pathway mcc04370   VEGF signaling pathway mcc04371   Apelin signaling pathway mcc04666   Fc gamma R-mediated phagocytosis mcc05152   Tuberculosis Module mcc_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:mcc00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     710441 (SPHK1)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     710441 (SPHK1)    04371 Apelin signaling pathway     710441 (SPHK1)    04020 Calcium signaling pathway     710441 (SPHK1)    04072 Phospholipase D signaling pathway     710441 (SPHK1)    04071 Sphingolipid signaling pathway     710441 (SPHK1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     710441 (SPHK1)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     710441 (SPHK1) Enzymes [BR:mcc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      710441 (SPHK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat Motif Other DBs NCBI-GeneID:  710441 NCBI-ProteinID:  XP_014975919 Ensembl:  ENSMMUG00000018011 LinkDB All DBs Position 16 AA seq 499 aa AA seqDB search MSREPRAPPHGLRAMRERATPRAWSRDLVGPSPPLGAAAPDSASAVFSTSDPAAAGNDAG APTATAPDGEGEPHSRPCDARLGSTDKELKAGAAATGSAPTAPGTPRQREPRVEVMDPAG GPRGVLPRSCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVR SEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAG YEQVTNEDLLTNCTRLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYR RLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRAGSKTPVSPVVVQQGPVDAHLVPLEEPV PSHWTVVPDQDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLA MEKGRHMEYECPYLVYMPVVAFRLEPEDGRGVFTVDGELMVSEAVQGQVHPNYFWMVSEC VEPLPSWKPQQTPPPEEPL NT seq 1500 nt NT seq  +upstreamnt  +downstreamnt atgtcccgggaacctagggccccgccccacgggcttcgggcgatgcgggagcgcgcaact ccccgcgcgtggtcccgggatttagtcgggccctccccgcctttgggagctgcggctccg gactccgccagcgctgtcttctctacctcagatccagccgccgcagggaatgacgccggt gctcctacagccacggctccggacggggagggcgagccccacagccggccctgcgacgcc cgcctgggcagcaccgataaggagctgaaggcaggagccgccgccacgggcagtgccccg acagcgccagggaccccccggcagagggagccacgggtcgaggttatggatccagcgggc ggcccccggggcgtgctcccgcggtcctgccgcgtgctggtgctgctgaacccgcgtggc ggcaagggcaaggccctgcagctcttccggagtcacgtgcagccccttttggctgaggct gaaatctccttcacgctgatgctcactgagcggcggaaccatgcgcgggagctggtgcgg tcggaggagctgggccgctgggacgctctggtggtcatgtctggagacggactgatgcac gaggtggtgaacgggctcatggagcggcctgactgggagaccgccatccagaagcccctg tgtagcctcccagcaggctctggcaacgcgctggcagcttccttgaaccattatgctggc tatgagcaggtcaccaatgaagacctcctgaccaactgcacgcggttgctgtgccgccgg ctactgtcacccatgaacttgctgtctctgcacacggcttcggggctgcgcctcttctct gtgctaagcctggcctggggcttcattgctgatgtggacctagagagtgagaagtatcgg cgcctgggggagatgcgcttcactctgggcaccttcctgcgtctggcagccctgcgcact taccgtggccgactggcctacctccctgtaggaagagccggctctaagacacctgtttct cccgttgtggtccagcagggccccgtagatgcacaccttgtgccattggaggagccagtg ccctctcactggacagtggtgcccgaccaggatttcgtgctggtgctagcgctgctgcac tcgcacctgggcagcgagatgtttgcggcacccatgggccgctgtgcagctggtgtcatg catctgttctatgtgcgggcgggagtgtctcgggccatgctgctgcgcctcttcctggcc atggagaagggcaggcatatggaatatgaatgcccttacttggtatacatgcctgtggtc gccttccgcttagagcccgaggatgggagaggtgtgtttacagtggatggggaattgatg gttagcgaggctgtgcagggccaggtgcacccaaactacttctggatggtcagtgagtgc gtggagcccctgcccagctggaagccccagcagacgccacctccagaagagcccttatga

Macaca mulatta (rhesus monkey): 718088 Help Entry 718088            CDS       T01028                                  Gene name SPHK2 Definition (RefSeq) sphingosine kinase 2   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc00600   Sphingolipid metabolism mcc01100   Metabolic pathways mcc04020   Calcium signaling pathway mcc04071   Sphingolipid signaling pathway mcc04072   Phospholipase D signaling pathway mcc04370   VEGF signaling pathway mcc04371   Apelin signaling pathway mcc04666   Fc gamma R-mediated phagocytosis mcc05152   Tuberculosis Module mcc_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:mcc00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     718088 (SPHK2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     718088 (SPHK2)    04371 Apelin signaling pathway     718088 (SPHK2)    04020 Calcium signaling pathway     718088 (SPHK2)    04072 Phospholipase D signaling pathway     718088 (SPHK2)    04071 Sphingolipid signaling pathway     718088 (SPHK2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     718088 (SPHK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     718088 (SPHK2) Enzymes [BR:mcc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      718088 (SPHK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat Motif Other DBs NCBI-GeneID:  718088 NCBI-ProteinID:  NP_001244416 Ensembl:  ENSMMUG00000022159 UniProt:  F6ZFF5 G7NNQ6 LinkDB All DBs Position 19 AA seq 653 aa AA seqDB search MNGLLEAEEQDQRPEQELTRSWGHRPRSTLVRAKTMAPPPPPLAASTPLLHGEFGSYPAR GPRFALTLTSQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTYP RSRRGSRRRTTRTFRTDGATTYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRPP RLLLLVNPFGGRGLAWQWCKNYVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDGI VTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDLL LNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTLG TVLGLATLHTYRGRLSYLPATVEPTSPTPVHSLPRAKSELTLTPDPAPPMAHSPLHRSVS DLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKTA LHSPVTEGAPVIPPSSGLPPPTADARVAASTCGLPDHLLPPLGTPLPPDWVTLEGDFVLM LAISPSHLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSQFSLGCPQLG YAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGLGTLLTGPPGCPGREP NT seq 1962 nt NT seq  +upstreamnt  +downstreamnt atgaatggactccttgaagcagaggagcaggaccagaggccggaacaggagctgaccagg agctggggccacaggcctaggagcaccctggtcagggctaagaccatggccccgccccca ccgccactggctgccagcaccccgctcctccatggcgagtttggctcctacccagcccga ggcccacgctttgccctcaccctcacgtcgcaggccctgcacatacagcggctgcgcccc aaacccgaagccaggccccggggtggcctggtcccgttggccgaggtctcaggctgctgc accctgcgaagccgtagcccctcagactcagcagcctacttctgcatctacacctaccct cggagccggcgcgggagccggcgcagaaccacccgcaccttccggacagatggggctacc acctacgaagagaaccgtgccgaggcccagcgctgggccaccgccctcacctgtctgctc cgaggactgccgctgcccggggatggggagatcacccctgacctgctacctcggccgccc aggttgctcctattggtcaatccctttggggggcggggcttggcctggcagtggtgtaag aactacgtgcttcccatgatttctgaagctgggctgtccttcaacctcatccagacagaa cgacagaaccacgctcgggagctggtccaggggctgagcctgagtgagtgggatggcatc gtcacggtctcgggagacgggctgctccatgaggtgctgaacgggctcctagatcgccct gactgggaggaagctgtgaagatgcctgtgggcatcctcccctgtggctcgggcaatgcg ctggccggagcagtgaaccagcacgggggatttgagccagccctgggcctcgacctgctg ctcaactgctcactgttgctctgccggggtggcggccacccactggacctgctctccgtg acgctggcctcgggctcccgctgtttctccttcctgtctgtggcctggggcttcgtgtca gatgtggatatccagagcgagcgcttcagggccttgggcagtgcccgcttcacactgggc acggtgctgggcctcgccacactgcacacctaccgcggacgcctctcctacctccccgcc actgtggaacccacctcgcccacccctgtccatagcctgccccgtgctaagtcagagctg accctaaccccagacccagccccgcccatggcccactcacccctgcatcgttctgtgtct gacctgcccctgcccctgccccaacctgccctggcctcccctggctcaccagaacccctg cccatcctgtccctcaacggtgggggcccagagctggctggggactggggtggggctggg gatgctccactgtccccggacccactgctgtcttcacctcctggctctcccaagacagct ctacactcacccgtcactgagggggcccccgtaattcccccatcttctgggctcccaccg cccaccgctgatgcccgggtagcggcctccacctgcggcctgcctgaccacctgctgcct ccgctgggcaccccactgcccccagactgggtgacgctggagggggactttgtgctcatg ttggccatatcgcccagccacctaggcgctgacctggtggcagctccgcacgcgcgcttc gacgacggcctggtgcacctgtgctgggtgcgtagcggcatctcgcgggctgcgttgcta cgccttttcctggccatggagcgtggtagccagttcagcctgggctgtccgcagctgggc tacgccgcggcccgtgccttccgcctagagccgctcacgccgcgcggcgtgctcacggtg gacggggagcaggtggagtatgggccgctacaggcacagatgcaccctggcctcggtaca ctgctcaccgggcctcctggctgcccagggcgggagccctga

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