Macaca mulatta (rhesus monkey): 714231
Help
Entry
714231 CDS
T01028
Gene name
NOS3
Definition
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00220
Arginine biosynthesis
mcc00330
Arginine and proline metabolism
mcc01100
Metabolic pathways
mcc04020
Calcium signaling pathway
mcc04022
cGMP-PKG signaling pathway
mcc04066
HIF-1 signaling pathway
mcc04071
Sphingolipid signaling pathway
mcc04151
PI3K-Akt signaling pathway
mcc04370
VEGF signaling pathway
mcc04371
Apelin signaling pathway
mcc04611
Platelet activation
mcc04915
Estrogen signaling pathway
mcc04921
Oxytocin signaling pathway
mcc04926
Relaxin signaling pathway
mcc04931
Insulin resistance
mcc04933
AGE-RAGE signaling pathway in diabetic complications
mcc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
714231 (NOS3)
00330 Arginine and proline metabolism
714231 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
714231 (NOS3)
04371 Apelin signaling pathway
714231 (NOS3)
04066 HIF-1 signaling pathway
714231 (NOS3)
04020 Calcium signaling pathway
714231 (NOS3)
04071 Sphingolipid signaling pathway
714231 (NOS3)
04022 cGMP-PKG signaling pathway
714231 (NOS3)
04151 PI3K-Akt signaling pathway
714231 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
714231 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
714231 (NOS3)
04921 Oxytocin signaling pathway
714231 (NOS3)
04926 Relaxin signaling pathway
714231 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
714231 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
714231 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
714231 (NOS3)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
714231 (NOS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
HTH_15
Motif
Other DBs
NCBI-GeneID:
714231
NCBI-ProteinID:
XP_014990773
Ensembl:
ENSMMUG00000020437
UniProt:
F6WEB2
LinkDB
All DBs
Position
3
AA seq
1205 aa
AA seq
DB search
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATSAPEPSRAPASLPPPAPEHSPPSSPLT
QPPEGPKFPRVKNWEVGSIAYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP
EQLLSQARDFINQYYSSIRRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA
RDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP
PPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY
EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSRE
PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDT
NTNGP
NT seq
3618 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtggcccaggaacctgggccaccctgtggcctggggctgggg
ctgggccttgggctgtgcggcaagcagggcccagccacctcagcccctgagcccagccgg
gccccggcatccctacccccgccagcaccagaacacagccccccgagctccccgctaacc
cagcccccggaggggcccaagttccctcgtgtgaagaactgggaggtggggagcatcgcc
tatgacaccctcagcgcccaggcgcagcaggatgggccctgcaccccaagacgctgcctg
ggctccctggtatttccacggaaactacagggccggccctcccctggccccccggcccct
gagcagctgctgagtcaggcccgggacttcatcaaccagtactacagctccatcaggagg
agcggctcccaggcccacgaacagcggcttcaagaggtggaagccgaggtggcagccaca
ggcacctaccagcttagggagagcgagctcgtgttcggggccaagcaggcctggcgcaac
gctccccgctgtgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggac
tgcaggtcggcacaggaaatgttcacctacatctgcaaccacatcaaatacgccaccaac
cggggcaaccttcgctcggccatcacagtgttcccgcagcgctgccctggccgaggagac
ttccgaatctggaacagccagctggtgcgctatgcgggctaccggcagcaggacggctct
gtgcggggggacccagccaacgtcgagatcaccgagctctgcattcagcatggctggacc
ccaggaaacggtcgctttgacgtgctgcccctgctgctgcaggccccggatgagccccca
gaactcttccttctgccccctgagctggtccttgaggtgcccctggagcaccctacgctg
gagtggtttgcagccctgggcctgcgctggtacgccctcccagcagtgtccaacatgctg
ctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcact
gagatcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggacgtggct
gtctgcatggacctggatacccggacaacttcgtccctatggaaagacaaggcagcggtg
gaaatcaacgtggccgtgctgcacagttaccagctggccaaagtcaccattgtggaccac
cacgctgccacagcctccttcatgaagcacctggagaatgagcagaaggccagggggggc
tgccctgcagactgggcctggatcgtgccccccatctcgggcagcctcactcctgtcttc
catcaggagatggtcaactatttcctgtcaccagccttccgctaccagccagacccctgg
aaggggagtgcggccaagggcaccggcatcaccaggaagaagacctttaaagaagtggcc
aatgccgtgaagatctctgcctcgctcatgggcaccgtgatggcgaagcgagtgaaggcg
acaatcctgtatggctccgagaccggccgggcccagagctacgcacagcagctggggaga
cttttccggaaggcttttgatccccgggtcctgtgtatggatgagtatgacgtggtgtcc
ctcgaacacgagacgctggtgctggtggtaaccagcacattcgggaatggggatcccccg
gagaatggagagagctttgcagctgccctgatggagatgtccggtccctacaacagctcc
cctcggccggaacagcacaagagttataagatccgcttcaacagcatctcctgctcagac
ccactggtgtcctcttggcggcggaagaggaaggagtccagtaacacagacagtgcaggg
gccctgggcacactcaggttctgtgtgttcgggctgggctcccgggcctacccccacttc
tgcgcctttgctcgtgcggtggacacgcggctggaggaactgggcggggagcggctgctg
cagctgggccagggcgacgagctgtgtggccaggaggaggccttccgcggctgggcccag
gctgccttccaggccgcctgtgagaccttctgtgtgggagaggatgccaaggctgctgcc
cgagacatcttcagccccaaaaggagttggaagcgccagaggtaccggctgagcgcccag
gccgagggcctgcagttgctgccaggtctgatccacgtgcacaggcggaagatgttccag
gctacaattctctcagtggaaaacctgcaaagcagcaagtccacgagggccaccatcctg
gtgcgcctggacactggaggccaggaggggctgcagtaccagccgggggatcacataggt
gtctgcccacccaaccggcccggccttgtggaggcgctgctgagccgcgtggaggacccg
cctgcgcccaccgagcctgtggcagtagagcaactggagaagggcagccctggtggccct
ccccccagctgggtgcgggacccccggctgcccccatgcacgctgcgccaggctctcacc
ttcttcctggacatcacctccccgcccagccctcagctcttgcggctgctcagcaccttg
gcagaagagcccagggaacagcaggagctggaggccctcagtcaggatccccgacgctac
gaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccgtcg
gtggcactgcctgccccactgctcctcacccagctgcctctgctccaaccccggtactat
tcagtcagctcagcacccagcacccacccaggagagatccacctcactgtagctgtgctg
gcatacaggacccaggatgggctgggccccctgcactatggagtctgctccacgtggcta
agccaactcaagcccggagaccctgtgccctgcttcatccggggggctccctccttccgg
ctgccacctgatcccagcttgccctgcatcctggtgggcccaggcactggcattgccccc
ttccggggattctggcaggagcggctgcatgacattgagagcaaagggctgcagcccact
cccatgactttggtgtttggctgccgatgctcccaactcgaccatctctaccgcgacgag
gtgcagaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaa
cctgacaaccccaagacctacgtgcaggacatcctgaggaccgagctggctgcggaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcaccatggca
accaacgtcctgcagaccgtgcagcgcatcctggcaacggagggcgacatggagctggac
gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttc
gggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttg
caggagcggcagctacggggcgcagtgccctgggcgttcgacccgcccggctcggacacc
aacaccaacggcccctga
DBGET
integrated database retrieval system
