KEGG   Macaca mulatta (rhesus monkey): 714374
Entry
714374            CDS       T01028                                 

Gene name
PTPN6
Definition
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X1
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc04520  Adherens junction
mcc04630  JAK-STAT signaling pathway
mcc04650  Natural killer cell mediated cytotoxicity
mcc04660  T cell receptor signaling pathway
mcc04662  B cell receptor signaling pathway
mcc05140  Leishmaniasis
mcc05205  Proteoglycans in cancer
mcc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    714374 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    714374 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    714374 (PTPN6)
   04660 T cell receptor signaling pathway
    714374 (PTPN6)
   04662 B cell receptor signaling pathway
    714374 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    714374 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    714374 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    714374 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mcc01009]
    714374 (PTPN6)
Enzymes [BR:mcc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     714374 (PTPN6)
Protein phosphatases and associated proteins [BR:mcc01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    714374 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 714374
NCBI-ProteinID: XP_015006430
Ensembl: ENSMMUG00000010203
UniProt: A0A5K1UTD3
LinkDB
Position
11
AA seq 626 aa
MPSQLPRSSQHLTLVPSSFRFLSLPVPLHHSFNRWFHRDLSGLDAETLLKGRGVHGSFLA
RPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGVLQDR
DGTIIHLKYPLNCSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSV
LSDQPKAGPGSPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYL
RQPYYATRVNAADIENRVLELNKKKESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPE
NKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENTKTYIASQGCLE
ATVNDFWQMAWQENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGPYSVTNCGEHDTTE
YKLRTLHVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPI
IVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY
VAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHS
KNKREEKVKKQRSADKEKSKGSLKRK
NT seq 1881 nt   +upstreamnt  +downstreamnt
atgcccagccaacttccccgctcttcccaacatctgactttggtcccatcttccttccgt
ttcctttcacttcccgttcccctgcatcattcattcaacaggtggtttcaccgagacctc
agtgggctggatgcagagaccctgctcaagggccgaggtgtccatggcagcttcctggct
cggcccagtcgcaagaaccagggtgacttctccctctctgtcagggtgggggatcaggtg
acccatattcggatccagaactcaggggatttctatgacctgtatggaggggagaagttc
gcgacgctgacagagctggtggagtactacactcagcagcagggcgtcctgcaagaccgc
gacggcaccatcatccacctcaagtacccgctgaactgctccgatcccaccagtgagagg
tggtaccatggccacatgtctggagggcaggcagagacgctgctgcaggccaagggcgag
ccctggacatttcttgtgcgtgagagcctcagccagcctggagattttgtgctatctgtg
cttagtgaccagcccaaggctggcccaggctccccgctcagggtcacccacatcaaggtc
atgtgtgagggtggacgctacacagtgggtggttcagagaccttcgacagcctcacggac
ctggtggagcacttcaagaagacggggattgaggaggcctcaggtgcctttgtctacctg
cggcagccgtactacgccacgagggtgaatgcggctgacattgagaaccgagtcttggaa
ctgaacaagaagaaggagtctgaggatacagccaaggctggcttctgggaggagtttgag
agtttgcagaagcaggaggtgaagaacttgcaccagcgtctggaagggcagcggccagag
aacaagggcaagaaccgctataagaacattctgccctttgaccacagccgagtgatcctg
cagggacgtgacagtaacatcccggggtccgactatatcaatgccaactacatcaagaac
cagctgctaggccctgatgagaacactaagacctacatcgccagccagggctgtctagag
gccacggtcaacgacttctggcagatggcgtggcaggagaacacccgcgtcatcgtcatg
accacccgagaggtggagaaaggccggaacaaatgtgtcccatactggcccgaggtgggc
actcagcgcgtttatgggccctactctgtgaccaactgcggggagcatgacacgaccgaa
tacaaactccgcaccttacacgtctccccactggacaatggggacctcattcgggagatc
tggcattaccagtacctgagctggcccgaccatggggtccccagtgagcctgggggtgtc
ctcagcttcctggaccagatcaaccagcggcaggaaagtctgcctcatgcagggcccatc
atcgtgcactgcagcgccggcattggccgcacgggcaccatcattgtcatcgacatgctc
atggagaacatctccaccaagggcttggactgtgacattgacatccagaagaccatccag
atggtgcgggcacagcgctcaggcatggtgcagacagaggcgcagtacaagttcatctac
gtggccattgcccagttcattgaaaccaccaagaagaagctggaggtcctgcagtcgcag
aagggccaggagtcggagtatgggaacatcacctaccccccagccatgaagaacgcccat
gccaaggcctcccgcacctcgtccaaacacaaggaggatgtgtatgagaacctgcacagt
aagaacaagagggaggagaaagtgaagaagcagcggtcagcagacaaggagaagagcaag
ggttccctcaagaggaagtga

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