KEGG   Macaca mulatta (rhesus monkey): 721712
Entry
721712            CDS       T01028                                 

Gene name
FLT3
Definition
(RefSeq) LOW QUALITY PROTEIN: receptor-type tyrosine-protein kinase FLT3
  KO
K05092  fms-related tyrosine kinase 3 [EC:2.7.10.1]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc04010  MAPK signaling pathway
mcc04014  Ras signaling pathway
mcc04151  PI3K-Akt signaling pathway
mcc04640  Hematopoietic cell lineage
mcc05200  Pathways in cancer
mcc05202  Transcriptional misregulation in cancer
mcc05221  Acute myeloid leukemia
mcc05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    721712 (FLT3)
   04014 Ras signaling pathway
    721712 (FLT3)
   04151 PI3K-Akt signaling pathway
    721712 (FLT3)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    721712 (FLT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    721712 (FLT3)
   05202 Transcriptional misregulation in cancer
    721712 (FLT3)
   05230 Central carbon metabolism in cancer
    721712 (FLT3)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    721712 (FLT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcc01001]
    721712 (FLT3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mcc04090]
    721712 (FLT3)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     721712 (FLT3)
Protein kinases [BR:mcc01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   721712 (FLT3)
CD molecules [BR:mcc04090]
 Proteins
  721712 (FLT3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 Ig_2 I-set APH ig
Other DBs
NCBI-GeneID: 721712
NCBI-ProteinID: XP_028693282
Ensembl: ENSMMUG00000016139
LinkDB
Position
17
AA seq 993 aa
MPALARGGGRLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESP
EDLGCALRPQSAGTVYEAATVEVDVSASITLQVLVDTPXNVSCLWVFKHSSLNCQPHFDV
QNRGVVSMVILKMTXTQAGEYLXFIQSEATNYTILFTVSIRNTLLFTLRRPYFRKMENQD
ALVCISESVPEPIVEWVLCDSQGESCKERKSSSCXKEEKVLHEIFGXDIRCCARMNGQGM
ATRLFTIGLNQSPQTTLPQYSKVGNLMIRCKAVHVNXGFGLTWDXKTKHLEEGQLLEMST
IQQQNLIRILFAFXSSVAEHTGYYTCSSSSIQSSALVLLTEKGFINATNSSEDYEIDXYE
EFCFSVXFKAYPQIRCTWTFSRKSFXCEQKALDDGYSVSKFCNHKHQPGEYIYVSQCRKW
CMPISFYFTKFSAEYKRKPQVLAEASASQASCSSDGYPLPSWTWKKCSDKSPNCTEDIPE
GVWNRKANRKVFGQWVSSSTLNMSEAMKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQD
SISFYATIGVCLLFIVVLTMLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFRDCDYD
LKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMS
ELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKE
HNFSFYPTFQSHPNSSMPGSRDVQIHPHSDPISGLHGNSFHSEDEIEYENQKRLEEEEDL
NVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDS
NYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYK
LIRNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPHLTSFLGCQLEDAEEAMYQNVDG
RVSERPHIYQNRRPFSREMDSGPLSPKAQVEDS
NT seq 2982 nt   +upstreamnt  +downstreamnt
atgccggcgttggcgcgcggcggcggccggctgccgctgctcgttgttttttctgcaatg
atatttgggactattacaaatcaagatctgcctgtgatcaagtgtgttttaatcaatcat
aagaacaatgattcatcagtggggaagtcatcatcatatcccatggtgtcagaatcccca
gaagacctcgggtgtgcattgagaccccagagcgcagggacagtgtatgaagccgccacg
gtggaagtggatgtatctgcttccatcacattgcaagtgctggtcgacaccccanggaac
gtttcctgtctctgggtctttaagcacagctccctgaattgtcagccacattttgatgta
caaaatagaggagttgtttccatggtcattttgaaaatgacangaacccaagctggagaa
tacctancttttattcagagtgaagctaccaattacacaatattgtttacagtgagtata
agaaataccctgcttttcacattaagaagaccttactttagaaaaatggaaaaccaggac
gccctggtctgcatatctgagagcgttccagagccgatcgtggaatgggtgctttgcgat
tcacagggggaaagttgtaaagaaagaaagtccagcagttgttaaaaggaggagaaagtg
cttcatgagatatttggancggacataaggtgctgtgccagaatgaatgggcagggaatg
gcaaccaggctgttcacaataggtctaaatcaatctcctcagaccacattgccacaatat
tctaaagtggggaaccttatgataaggtgcaaagctgttcatgtgaacnctggattcggg
ctcacctgggattagaaaacaaagcacttggaggaagggcagctacttgagatgagtact
attcaacaacagaacttgatacggattctgtttgcttttngttcatcagtggcagaacac
acgggatactacacttgttcctcttcaagcatccagtcatccgctttggttcttcttaca
gaaaagggatttataaatgctaccaattcaagtgaagattatgaaattgacncatatgaa
gagttttgtttttccgtcnagtttaaagcctacccacaaatcagatgtacatggaccttc
tctcgaaaatcatttncttgtgagcaaaaggctctcgatgacggatacagcgtatccaag
ttttgcaatcataagcaccagccaggagaatatatatatgtatcccaatgcagaaaatgg
tgtatgccaatttcattttattttaccaaattttcagctgaatataagaggaaacctcaa
gtgctcgcggaagcatcagcgagtcaggcgtcctgttcctcggatggatacccattacca
tcttggacctggaagaagtgttcagacaagtctcctaactgcacagaagacatcccagaa
ggagtctggaatagaaaggctaacagaaaagtgtttggacagtgggtgtccagcagtact
ctaaacatgagtgaagccatgaaagggttcctggtcaagtgctgtgcatacaattccctt
ggcacatcttgtgagacgatccttttaaactctccaggccccttccctttcatccaagac
agcatctcattctatgcaacaattggtgtttgtctcctcttcattgtcgttttaaccatg
ctgatttgtcacaagtacaaaaagcaatttaggtatgaaagccagctacagatggtacag
gtgaccggctcctcagataatgagtacttctacgttgatttcagagactgtgactatgat
ctcaaatgggagtttccaagagaaaatttagagtttgggaaggtgctaggatcaggggct
tttggaaaagtgatgaacgcaacagcttatggaattagcaaaacaggagtctcaatccag
gttgcagtcaaaatgctgaaagaaaaagcagacagctctgaaagagaggcactcatgtca
gaactcaagatgatgacccagctgggaagccacgagaatattgtgaacctgctgggggcg
tgcacgctgtcaggaccaatttacttgatttttgaatattgttgctatggtgatcttctc
aactatctaagaagtaaaagagaaaaatttcacaggacttggacagagattttcaaggaa
cacaatttcagtttttaccccactttccaatcacatccaaattccagcatgcctggttca
agagacgttcagatacacccgcactcggatccaatctcagggcttcatgggaattcattt
cactctgaagatgaaattgaatatgaaaaccaaaaaaggctggaagaagaggaggacttg
aatgtgcttacatttgaagatcttctttgctttgcatatcaagttgccaaaggaatggaa
tttctggaatttaagtcgtgtgttcacagagacctggccgccaggaacgtgcttgtcacc
cacgggaaagtggtgaagatatgtgactttggattggctcgagatatcatgagtgattcc
aactatgttgtcaggggcaatgcccgtctgcctgtaaaatggatggcccctgaaagccta
tttgaagggatctataccattaagagtgatgtctggtcatacggaatattactgtgggaa
atcttctcacttggtgtgaatccttaccctggcattccggttgatgctaacttctacaaa
ctgattcgaaatggatttaaaatggatcagccattttatgctacagaagaaatatacatt
ataatgcaatcctgctgggcttttgactcaaggaagcggccatccttccctcatttgact
tcatttttaggatgtcagctggaggatgcggaagaagcgatgtatcagaatgtggatggc
cgtgtttcggaacgtcctcacatctaccaaaacaggcgacctttcagcagagagatggat
tcagggccactctctccaaaggctcaggtcgaagattcatag

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