KEGG   Macaca fascicularis (crab-eating macaque): 101867036Help
Entry
101867036         CDS       T02918                                 

Gene name
PTEN
Definition
(RefSeq) phosphatase and tensin homolog
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00562  Inositol phosphate metabolism
mcf01100  Metabolic pathways
mcf01521  EGFR tyrosine kinase inhibitor resistance
mcf04068  FoxO signaling pathway
mcf04070  Phosphatidylinositol signaling system
mcf04071  Sphingolipid signaling pathway
mcf04115  p53 signaling pathway
mcf04140  Autophagy - animal
mcf04150  mTOR signaling pathway
mcf04151  PI3K-Akt signaling pathway
mcf04218  Cellular senescence
mcf04510  Focal adhesion
mcf04931  Insulin resistance
mcf05165  Human papillomavirus infection
mcf05166  Human T-cell leukemia virus 1 infection
mcf05200  Pathways in cancer
mcf05206  MicroRNAs in cancer
mcf05213  Endometrial cancer
mcf05214  Glioma
mcf05215  Prostate cancer
mcf05218  Melanoma
mcf05222  Small cell lung cancer
mcf05224  Breast cancer
mcf05225  Hepatocellular carcinoma
mcf05230  Central carbon metabolism in cancer
mcf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101867036 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    101867036 (PTEN)
   04070 Phosphatidylinositol signaling system
    101867036 (PTEN)
   04071 Sphingolipid signaling pathway
    101867036 (PTEN)
   04151 PI3K-Akt signaling pathway
    101867036 (PTEN)
   04150 mTOR signaling pathway
    101867036 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101867036 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    101867036 (PTEN)
   04218 Cellular senescence
    101867036 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101867036 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101867036 (PTEN)
   05206 MicroRNAs in cancer
    101867036 (PTEN)
   05230 Central carbon metabolism in cancer
    101867036 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101867036 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101867036 (PTEN)
   05214 Glioma
    101867036 (PTEN)
   05218 Melanoma
    101867036 (PTEN)
   05215 Prostate cancer
    101867036 (PTEN)
   05213 Endometrial cancer
    101867036 (PTEN)
   05224 Breast cancer
    101867036 (PTEN)
   05222 Small cell lung cancer
    101867036 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101867036 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101867036 (PTEN)
   05165 Human papillomavirus infection
    101867036 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101867036 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mcf01009]
    101867036 (PTEN)
Enzymes [BR:mcf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     101867036 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     101867036 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     101867036 (PTEN)
Protein phosphatases and associated proteins [BR:mcf01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    101867036 (PTEN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PTEN_C2 DSPc Y_phosphatase Y_phosphatase3 PTPlike_phytase DUF3256
Motif
Other DBs
NCBI-GeneID: 101867036
NCBI-ProteinID: XP_005565939
UniProt: A0A2K5WAK8
LinkDB All DBs
Position
9
AA seq 403 aa AA seqDB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1212 nt NT seq  +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctttgtgctgaaagacattatgacaccgccaaa
tttaattgcagagttgcacaatatccttttgaagaccataacccaccacagctagaactg
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcacctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggccccacacgacgggaagacaagttcatgtac
tttgagttccctcagccgttacctgtgtgtggtgatatcaaagtagagttcttccataaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagcatttgcagtatagagcgtgcagataatgacaaggaatatctagtacttacttta
acaaaaaatgatcttgacaaagcaaataaagacaaagccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccgtcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga

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