KEGG   MODULE: M00642
Entry
M00642            Signature Module                                 
Name
Multidrug resistance, efflux pump MexJK-OprM
Definition
K18301 K18302+K18303-K18139
Diagram
M00642

Orthology
K18301  
mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
K18302  
mexJ; membrane fusion protein
K18303  
mexK; multidrug efflux pump
K18139  
oprM; outer membrane protein
Class
Signature modules; Gene set; Drug resistance
Reference
  Authors
Chuanchuen R, Narasaki CT, Schweizer HP
  Title
The MexJK efflux pump of Pseudomonas aeruginosa requires OprM for antibiotic efflux but not for efflux of triclosan.
  Journal
J Bacteriol 184:5036-44 (2002)
DOI:10.1128/JB.184.18.5036-5044.2002
Reference
  Authors
Depardieu F, Podglajen I, Leclercq R, Collatz E, Courvalin P
  Title
Modes and modulations of antibiotic resistance gene expression.
  Journal
Clin Microbiol Rev 20:79-114 (2007)
DOI:10.1128/CMR.00015-06
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