KEGG   Monodelphis domestica (opossum): 100031311Help
Entry
100031311         CDS       T01031                                 

Gene name
HK1
Definition
(RefSeq) hexokinase 1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
mdo00010  Glycolysis / Gluconeogenesis
mdo00051  Fructose and mannose metabolism
mdo00052  Galactose metabolism
mdo00500  Starch and sucrose metabolism
mdo00520  Amino sugar and nucleotide sugar metabolism
mdo00524  Neomycin, kanamycin and gentamicin biosynthesis
mdo01100  Metabolic pathways
mdo01200  Carbon metabolism
mdo04066  HIF-1 signaling pathway
mdo04910  Insulin signaling pathway
mdo04930  Type II diabetes mellitus
mdo04973  Carbohydrate digestion and absorption
mdo05230  Central carbon metabolism in cancer
Module
mdo_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100031311 (HK1)
   00051 Fructose and mannose metabolism
    100031311 (HK1)
   00052 Galactose metabolism
    100031311 (HK1)
   00500 Starch and sucrose metabolism
    100031311 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    100031311 (HK1)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100031311 (HK1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    100031311 (HK1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100031311 (HK1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    100031311 (HK1)
 09160 Human Diseases
  09161 Cancers
   05230 Central carbon metabolism in cancer
    100031311 (HK1)
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100031311 (HK1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mdo04131]
    100031311 (HK1)
Enzymes [BR:mdo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     100031311 (HK1)
Membrane trafficking [BR:mdo04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    100031311 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hexokinase_2 Hexokinase_1 DEAD Pyridoxal_deC RIBIOP_C
Motif
Other DBs
NCBI-GeneID: 100031311
NCBI-ProteinID: XP_001380610
LinkDB All DBs
Position
Un
AA seq 919 aa AA seqDB search
MIAAQLLAYYFTELKDDQIKKIDKYLYAMRLSDDVLHEVTNRFKKAMSNGLSRNYNVTAS
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVSHDKNQHVEMDSEVYETPDRIMR
GSGPELFDHVAECLGNFMEKKKIKDKNLPIGFTFSFPCRQTKINEAVLITWTKRFKVSGV
EGSDVVQLLNKAIKKRGEYEANIMAVVNDTVGTMMTCAFDDPECEVGLIVGTGTNACYME
ELRHIDMVEGDEGRMCINTEWGSFGDDGCINEIRTEFDKEIDRGSLNPGKQLFEKMVSGM
YMGELVRLIIVKMAKGGLLFDGRLTPELLTKGKFETKNVSAIEKTKEGLDRAKDILTNLG
LEPSPEDCVSVQHVCAIVSHRSANLVAAMLAGILFRLKENKNLPRLRTTVGVDGTLYKFH
PQYSRRLQKTLRRLFPDSDVRFILSESGSGKGAAMVTAVAYRLAEQQKHMAEMLAPLKLT
SQQLMQVKNRLRVEMDLGLKKSSHDSAKVKMWPSYVTGTLDGSESGDFLALDLGGTNFRV
LLVKIRSGKKKSVEMHNKIYAIPESVMQGTGEELFDHIVSCISDFLDYMGMKTARLPLGF
TFSFPCHQTSLDGGTLVTWTKGFNASNCVGQDVPTLLRDAIKRRGEFDLDVVALVNDTVG
TMMTCAYEERTCEVGLIVGTGSNACYMEEMKNIELVEGNEGRMCINMEWGAFGDNGCLED
LRTEYDRIVDDFSLNAGKQRYEKMISGMYLGEIVRNILIDFTKNGFLFRGHISEALKTRG
IFKTKFLSQIESDRLALLQVRVILQELGLNSTCDDSILVKMVCGVVSKRAAQLCGAGVAA
VVDKIRENRNLETLKVTVGVDGTLYKLHPHFSRIMNQTVQDLAPKCNVKFLLSEDGSGKG
AALISAVGVRLREGKGKAS
NT seq 2760 nt NT seq  +upstreamnt  +downstreamnt
atgatcgcggcgcagctgctagcttattactttaccgaattaaaggatgaccagatcaag
aagatcgacaagtatctttatgccatgcggctctcagatgacgtccttcacgaggtcacg
aatcgatttaagaaagcaatgtcaaatgggctttccagaaattataatgtaactgcttct
gtgaagatgctaccaacatttgtgagatccattcctgatggctcagaaaagggagatttc
attgctctggatcttggggggtcttcctttcgaattctacgggtgcaagtgtctcatgat
aaaaatcagcacgttgagatggattcagaggtttatgaaaccccagaccgtataatgcgt
ggcagtggacctgagctttttgatcatgttgctgaatgccttggaaacttcatggagaaa
aagaagatcaaagataagaacttacccattggatttactttctccttcccctgtcgacag
acaaaaatcaatgaggctgttctgatcacctggaccaagcgctttaaggtcagcggagtg
gagggttctgacgtggtccagctgctcaacaaagcaatcaagaagcgaggggaatatgaa
gccaacatcatggctgtcgtgaacgacactgtggggacgatgatgacctgtgccttcgat
gacccagagtgtgaagtgggcctgatcgttggtaccggcaccaacgcctgctacatggaa
gaactgaggcacatcgacatggttgaaggggatgaagggcgtatgtgcatcaacacagaa
tgggggtcctttggggatgacggctgcatcaatgaaattcgcacagaatttgacaaagag
attgaccggggatccctcaatcctgggaagcagctatttgagaagatggtcagtggcatg
tacatgggggagcttgtcagactgattattgtaaagatggcgaaggggggcctcctattt
gatgggcggctcacacctgagctactcaccaaagggaaatttgagaccaagaatgtatca
gccattgagaaaaccaaggaaggtctcgacagagccaaagatatcctgaccaaccttggc
ttggagccatcccccgaagattgtgtctctgtccagcatgtgtgtgccattgtctcacat
cgatcggccaatctggtggctgccatgttggctggcatcttgttccgcctgaaagaaaac
aaaaatttgcctcggctgcggaccacagttggggttgatggaacgctgtacaagtttcat
ccacagtactcccgccgattgcagaaaaccctgcggcgcttgttccctgactctgatgtg
cgcttcatcctctccgagagtgggagtgggaagggggctgccatggtgaccgctgtggcc
tatcggctggccgagcaacagaagcatatggccgagatgctggcccccttgaagcttaca
tctcagcagctcatgcaggtgaagaacagactgcgagtggagatggacctggggctaaag
aagagcagccacgatagtgccaaggtgaagatgtggccatcctacgtgactggtaccctg
gacggttctgagtctggagacttcttagccctggaccttgggggcacaaacttccgggtc
ctgctggtgaagatccgtagtgggaaaaagaagagtgttgaaatgcataacaaaatctat
gccattcctgagtcagtgatgcagggcaccggagaggagcttttcgaccacattgtttcc
tgtatctctgactttctggattatatggggatgaaaactgcccggttgccccttggcttc
acgttctcctttccttgccaccagacgagtttggatgggggcaccctggtcacgtggacg
aagggctttaatgcatccaactgtgtaggacaagatgtgcccaccttgctgagagacgca
attaaaaggagaggggaatttgacctggatgttgtggctttggtcaatgatactgtgggc
accatgatgacctgtgcttatgaagaacggacttgtgaagttggactcattgtagggaca
ggaagcaatgcctgctacatggaagagatgaagaatattgagctggtggaggggaatgag
ggacggatgtgcatcaacatggagtggggtgcttttggggacaatggatgcctagaagac
cttaggacggagtatgaccgaatcgtggatgatttttccctcaatgctggcaaacagagg
tatgagaagatgattagcgggatgtacttgggagaaatcgtccgaaacattttaattgac
ttcaccaagaatggtttcctgttccgaggccacatttctgaggctttgaaaacccgggga
atctttaagaccaagttcctgtcacagattgaaagtgataggttggccctgctccaggtc
cgagtgattctgcaggagctgggtctaaacagcacctgtgacgacagtatccttgtcaag
atggtctgtggggtcgtgtccaagagggctgcccagctctgcggggctggggtggcagct
gttgtggacaagatcagggaaaacaggaatctggaaactctgaaagtgactgtaggagtt
gacgggacactctataaactccatcctcatttctccaggatcatgaatcagacagtgcag
gatctggcccccaaatgtaacgtcaaattcctcctctcagaagacggcagtgggaaggga
gcggcactcatctcggctgtcggggtgaggctccgagagggcaaaggcaaggccagctaa

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