KEGG   Manis javanica (Malayan pangolin): 108384835
Entry
108384835         CDS       T06054                                 

Gene name
PTPN6
Definition
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X1
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv04520  Adherens junction
mjv04630  JAK-STAT signaling pathway
mjv04650  Natural killer cell mediated cytotoxicity
mjv04660  T cell receptor signaling pathway
mjv04662  B cell receptor signaling pathway
mjv05140  Leishmaniasis
mjv05205  Proteoglycans in cancer
mjv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    108384835 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    108384835 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    108384835 (PTPN6)
   04660 T cell receptor signaling pathway
    108384835 (PTPN6)
   04662 B cell receptor signaling pathway
    108384835 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    108384835 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108384835 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    108384835 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mjv01009]
    108384835 (PTPN6)
Enzymes [BR:mjv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     108384835 (PTPN6)
Protein phosphatases and associated proteins [BR:mjv01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    108384835 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 108384835
NCBI-ProteinID: XP_017497521
LinkDB
Position
Unknown
AA seq 597 aa
MLSSGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTVIHLKYPLNCSDPTSERWYHGHMSGG
QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGLGSPLRVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPG
SDYINANYVKNQLLSPDENTKTYIASQGCLEATVNDFWQMVWQENTRVIVMTTREVEKGR
NKCVPYWPEVGSQRVYGPYAVTNCREHDTAEYKLRTLQVSPLDNGDLVREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGQESEYGN
ITYPPAMKNAHAKASRTSSKHKEDLYENLHGKNKKEEKVKKQRSADKEKSKGSLKRK
NT seq 1794 nt   +upstreamnt  +downstreamnt
atgctgtccagtgggtggtttcaccgagacctcagcgggctggacgcagagaccctgctc
aagggccgtggtgtccacgggagcttcctggctcggcccagtcgcaagaaccagggtgat
ttctccctctctgtcagggtgggggatcaggtgacccacattcggatccagaactctggg
gacttctatgacctgtatggaggggagaagttcgcaacgctcacggagctggtggagtac
tacacacagcagcagggcgtcctgcaggaccgcgatggcaccgtcatccacctcaagtac
cctctcaactgttctgaccccaccagtgagaggtggtaccatggtcacatgtctggaggg
caggcagagacactgctgcaagccaagggtgagccgtggacatttctcgtgcgtgagagt
ctcagccagcctggggactttgtgctgtccgtgcttagcgaccagcccaaggctggcctg
ggctccccactccgagtcacacatatcaaggtcatgtgtgagggtggacgctacacggtg
ggtggttcggagacctttgacagcctcacagaccttgtggagcatttcaagaagactggg
attgaggaggcctcaggtgccttcgtctacctgcggcagccatactatgccactcgggtg
aatgcagctgatattgagaaccgagttttggaactgaacaagaagcaagagtcagaggac
acagccaaggccggcttctgggaggagtttgagagtctgcaaaagcaggaggtgaagaac
ttgcaccagcggctggaagggcagcggccagagaacaagagcaagaaccgttataagaac
attctcccgtttgaccacagccgagtgatcctgcagggacgtgacagcaacatccctggg
tccgactacatcaacgctaactatgtcaagaaccagctgctgagccctgatgagaacact
aagacctacattgccagccagggctgcctggaggccacggtcaatgacttttggcagatg
gtatggcaggagaatacccgagtcattgtcatgaccacccgagaggtggagaaaggccgg
aacaagtgtgtcccgtactggccagaggtgggttctcagcgtgtttatgggccctatgct
gtcaccaactgcagggaacacgacactgctgagtacaaactccgcaccttacaggtctcc
ccactggacaatggggatctggttcgggagatctggcactaccagtacctgagctggcct
gaccatggagtccccagtgagcctgggggtgtcctcagcttcctggaccagatcaaccag
cggcaggaaagtctgcctcacgcggggcccatcatcgtgcattgcagcgcgggcattggc
cgcacaggcaccatcattgtcattgacatgctcatggagagcatctccaccaaggggctg
gactgtgacatcgacatccagaagacgatccagatggtgcgtgcccagcgctcgggcatg
gtgcagacggaggcgcagtacaagttcatttatgtggccattgcccagtttattgaaacc
accaagaagaagctggaggtcatgcagtcccagaaaggccaggagtcagagtacgggaac
atcacctaccccccagccatgaagaatgctcatgccaaggcctcacgcacctcctccaaa
cacaaggaagacttgtatgagaacctgcatggtaagaacaagaaggaagaaaaggtgaag
aagcagcggtcggcggacaaggagaagagcaagggatccctcaagaggaagtga

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