KEGG   Manis javanica (Malayan pangolin): 108391706
Entry
108391706         CDS       T06054                                 

Gene name
NFKB1
Definition
(RefSeq) nuclear factor NF-kappa-B p105 subunit
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv01523  Antifolate resistance
mjv04010  MAPK signaling pathway
mjv04014  Ras signaling pathway
mjv04024  cAMP signaling pathway
mjv04062  Chemokine signaling pathway
mjv04064  NF-kappa B signaling pathway
mjv04066  HIF-1 signaling pathway
mjv04071  Sphingolipid signaling pathway
mjv04151  PI3K-Akt signaling pathway
mjv04210  Apoptosis
mjv04211  Longevity regulating pathway
mjv04218  Cellular senescence
mjv04380  Osteoclast differentiation
mjv04613  Neutrophil extracellular trap formation
mjv04620  Toll-like receptor signaling pathway
mjv04621  NOD-like receptor signaling pathway
mjv04622  RIG-I-like receptor signaling pathway
mjv04623  Cytosolic DNA-sensing pathway
mjv04625  C-type lectin receptor signaling pathway
mjv04657  IL-17 signaling pathway
mjv04658  Th1 and Th2 cell differentiation
mjv04659  Th17 cell differentiation
mjv04660  T cell receptor signaling pathway
mjv04662  B cell receptor signaling pathway
mjv04668  TNF signaling pathway
mjv04722  Neurotrophin signaling pathway
mjv04917  Prolactin signaling pathway
mjv04920  Adipocytokine signaling pathway
mjv04926  Relaxin signaling pathway
mjv04931  Insulin resistance
mjv04932  Non-alcoholic fatty liver disease
mjv04933  AGE-RAGE signaling pathway in diabetic complications
mjv05010  Alzheimer disease
mjv05022  Pathways of neurodegeneration - multiple diseases
mjv05030  Cocaine addiction
mjv05132  Salmonella infection
mjv05133  Pertussis
mjv05134  Legionellosis
mjv05135  Yersinia infection
mjv05140  Leishmaniasis
mjv05142  Chagas disease
mjv05145  Toxoplasmosis
mjv05146  Amoebiasis
mjv05152  Tuberculosis
mjv05160  Hepatitis C
mjv05161  Hepatitis B
mjv05162  Measles
mjv05163  Human cytomegalovirus infection
mjv05164  Influenza A
mjv05165  Human papillomavirus infection
mjv05166  Human T-cell leukemia virus 1 infection
mjv05167  Kaposi sarcoma-associated herpesvirus infection
mjv05168  Herpes simplex virus 1 infection
mjv05169  Epstein-Barr virus infection
mjv05170  Human immunodeficiency virus 1 infection
mjv05171  Coronavirus disease - COVID-19
mjv05200  Pathways in cancer
mjv05202  Transcriptional misregulation in cancer
mjv05203  Viral carcinogenesis
mjv05206  MicroRNAs in cancer
mjv05212  Pancreatic cancer
mjv05215  Prostate cancer
mjv05220  Chronic myeloid leukemia
mjv05221  Acute myeloid leukemia
mjv05222  Small cell lung cancer
mjv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mjv05321  Inflammatory bowel disease
mjv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108391706 (NFKB1)
   04014 Ras signaling pathway
    108391706 (NFKB1)
   04064 NF-kappa B signaling pathway
    108391706 (NFKB1)
   04668 TNF signaling pathway
    108391706 (NFKB1)
   04066 HIF-1 signaling pathway
    108391706 (NFKB1)
   04071 Sphingolipid signaling pathway
    108391706 (NFKB1)
   04024 cAMP signaling pathway
    108391706 (NFKB1)
   04151 PI3K-Akt signaling pathway
    108391706 (NFKB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    108391706 (NFKB1)
   04218 Cellular senescence
    108391706 (NFKB1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    108391706 (NFKB1)
   04620 Toll-like receptor signaling pathway
    108391706 (NFKB1)
   04621 NOD-like receptor signaling pathway
    108391706 (NFKB1)
   04622 RIG-I-like receptor signaling pathway
    108391706 (NFKB1)
   04623 Cytosolic DNA-sensing pathway
    108391706 (NFKB1)
   04625 C-type lectin receptor signaling pathway
    108391706 (NFKB1)
   04660 T cell receptor signaling pathway
    108391706 (NFKB1)
   04658 Th1 and Th2 cell differentiation
    108391706 (NFKB1)
   04659 Th17 cell differentiation
    108391706 (NFKB1)
   04657 IL-17 signaling pathway
    108391706 (NFKB1)
   04662 B cell receptor signaling pathway
    108391706 (NFKB1)
   04062 Chemokine signaling pathway
    108391706 (NFKB1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    108391706 (NFKB1)
   04917 Prolactin signaling pathway
    108391706 (NFKB1)
   04926 Relaxin signaling pathway
    108391706 (NFKB1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    108391706 (NFKB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108391706 (NFKB1)
  09149 Aging
   04211 Longevity regulating pathway
    108391706 (NFKB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108391706 (NFKB1)
   05202 Transcriptional misregulation in cancer
    108391706 (NFKB1)
   05206 MicroRNAs in cancer
    108391706 (NFKB1)
   05203 Viral carcinogenesis
    108391706 (NFKB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108391706 (NFKB1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    108391706 (NFKB1)
   05221 Acute myeloid leukemia
    108391706 (NFKB1)
   05220 Chronic myeloid leukemia
    108391706 (NFKB1)
   05215 Prostate cancer
    108391706 (NFKB1)
   05222 Small cell lung cancer
    108391706 (NFKB1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    108391706 (NFKB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108391706 (NFKB1)
   05022 Pathways of neurodegeneration - multiple diseases
    108391706 (NFKB1)
  09165 Substance dependence
   05030 Cocaine addiction
    108391706 (NFKB1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    108391706 (NFKB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    108391706 (NFKB1)
   04931 Insulin resistance
    108391706 (NFKB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    108391706 (NFKB1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108391706 (NFKB1)
   05135 Yersinia infection
    108391706 (NFKB1)
   05133 Pertussis
    108391706 (NFKB1)
   05134 Legionellosis
    108391706 (NFKB1)
   05152 Tuberculosis
    108391706 (NFKB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108391706 (NFKB1)
   05170 Human immunodeficiency virus 1 infection
    108391706 (NFKB1)
   05161 Hepatitis B
    108391706 (NFKB1)
   05160 Hepatitis C
    108391706 (NFKB1)
   05171 Coronavirus disease - COVID-19
    108391706 (NFKB1)
   05164 Influenza A
    108391706 (NFKB1)
   05162 Measles
    108391706 (NFKB1)
   05168 Herpes simplex virus 1 infection
    108391706 (NFKB1)
   05163 Human cytomegalovirus infection
    108391706 (NFKB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108391706 (NFKB1)
   05169 Epstein-Barr virus infection
    108391706 (NFKB1)
   05165 Human papillomavirus infection
    108391706 (NFKB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    108391706 (NFKB1)
   05145 Toxoplasmosis
    108391706 (NFKB1)
   05140 Leishmaniasis
    108391706 (NFKB1)
   05142 Chagas disease
    108391706 (NFKB1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    108391706 (NFKB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mjv03000]
    108391706 (NFKB1)
Transcription factors [BR:mjv03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    108391706 (NFKB1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank_4 Ank Ank_5 Ank_3 Death
Other DBs
NCBI-GeneID: 108391706
NCBI-ProteinID: XP_017506930
LinkDB
Position
Unknown
AA seq 939 aa
MAEDNPYLGGHEQMFHLDPLTHTIFNPELFSSEMPLATDGPYLHILEQPKQRGFRFRYVC
EGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDG
ICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACTRGYNPGLLVHPDLAYLQAE
GGGDRQLTDREKEIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYD
SKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGDFS
PTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQR
KRQKLMPNFSDSFGGGSGAGAGGGGMFGGGGGGAGNAGPGTIVTPSEDDPEGCDSYDDRQ
AGNLSGKLTKTTEQDKLSGNGDDEVTLMYTVGAKEENYRFQDNLFLEKAMQLAKRHANAL
FDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLLEVTSGLISDDIIN
MRNDLYQTPLHLAVITEQEAVVEDLLRAGADLSLLDRLGNSVLHLAAKGGHDRLLSILLK
HKKAALLIDLPNGEGLNATHIATMSNSMPCLLLLVAAGADVNAQERKSGRTALHLAVEHD
NISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDL
DDSWEKDGEDEGVVPGTTPLDMATNWQVFDILNGKPYEPEFTSDDSPAQGDMKQLTEDAK
VQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTIKELVEAL
RQMGYTEAIEVIQAAFHTSGTAAPSPGQTSCQAASLPLSPASTRQQIDELRDDSICDSGV
ETSFRKLSFTESLTSGSSLLTLNKMPHEYGQEGPIEGKI
NT seq 2820 nt   +upstreamnt  +downstreamnt
atggcagaagacaatccatatttaggagggcatgaacaaatgtttcatttggatcctttg
actcatacaatatttaatccagaattattttcatcagagatgcctctagcaacagatggc
ccataccttcacatattagagcaacctaaacagagaggatttcgtttccgttatgtgtgt
gaaggcccatcccatggtggacttcctggtgcatccagtgaaaagaacaagaagtcctac
cctcaggtcaaaatctgcaactatgtgggacctgcaaaggttattgttcagttggtcaca
aatggcaaaaacatccaccttcatgcgcacagcctggtggggaagcactgtgaggatggc
atctgcactgtgaccgctggccccaaggacatggtggtcggctttgcaaacctgggtata
cttcatgtgacaaagaaaaaagtatttgaaaccctggaagcacgaatgacagaggcttgt
accaggggttataatcctggactcttggtgcaccctgatcttgcctatttgcaagcagaa
ggtggaggcgaccggcagctcacagatcgggaaaaggagatcatccgccaggcagctctt
cagcagacaaaggagatggacctcagtgtggtgcggctcatgtttacagcttttcttcca
gacagcacaggcagcttcacaaggcgcctcgagcctgtggtgtcagatgccatctatgac
agcaaagcccccaatgcgtccaacttgaaaattgtaagaatggacaggacggctggatgc
gtaactggaggggaagaaatttatcttctttgtgacaaggttcaaaaagatgacatccag
attcgattttatgaagaggaggaaaatggtggaatctgggaaggatttggagatttttcc
cccacagatgttcatagacaatttgccatcgtcttcaaaactccaaagtataaggatgtc
aacattacaaaaccagcctccgtgttcgtccaacttcggaggaaatctgatttggaaact
agcgaaccaaaaccttttctctactaccctgaaatcaaagataaagaggaagtgcagagg
aagcgacagaagctcatgcccaatttctctgatagcttcggcggcggcagcggtgctggg
gccggcggcgggggcatgttcggcggcggcggcggtggcgccggaaatgcgggcccaggt
accatagtcaccccatctgaagatgaccctgaaggctgtgacagctatgatgacagacag
gcaggaaatctctctgggaagctaactaaaaccacagaacaagataagctgtctggcaat
ggggatgatgaggttactctgatgtatacagttggagcaaaagaagagaattacagattt
caagataacttatttctagagaaggctatgcagcttgccaagcgccacgccaatgccctt
tttgactacgcagtgacaggagatgtgaagatgctgctggctgtccagcgccatctcact
gcagtgcaggatgagaacggggacagtgtcttacacttagcaatcatccaccttcatgct
cagcttgtgagggacttgctagaagtcacatctggtttgatttctgatgacattatcaac
atgagaaatgatctctaccagacgcccttgcacttggcagtgatcaccgagcaggaggct
gtggtggaggacttgctgagagcgggagccgacctgagcctcctggaccgcttgggtaac
tctgttttgcacctagctgccaaaggaggacatgacagacttctcagtattttactcaag
cacaaaaaggcggcactacttatcgacctccccaatggggaaggtctgaacgccacccac
atagccacgatgagcaacagcatgccctgtctgctgctgctggtagccgctggtgcggac
gtcaacgcccaggagcgcaagtctgggcgcacagcactgcacctggccgtggagcacgac
aacatctccctggctggctgcctgctcctggagggtgatgcccatgtagacagtaccacc
tacgatggaactacacccctgcacatagcagctgggagagggtccaccagactggcagct
cttctcaaagcagcaggagcagatcccctggtggagaactttgagcctctctatgacctg
gacgactcctgggaaaaggatggggaggacgaaggagtcgtgcctggaaccacaccacta
gatatggccaccaactggcaggtatttgacatattaaatgggaaaccatacgagccagag
tttacatccgatgactcaccggcgcaaggagacatgaaacagctgactgaagatgcgaag
gtgcagctctacaagttgctagaaatccctgatccagacaaaaactgggctactctggca
caaaaattgggtctggggatactaaataatgccttccggctaagtcctgctccttctaaa
acgcttatggataactacgaggtctctgggggaacaataaaagagctggtggaggccctg
agacagatgggctacactgaagccattgaagtgatccaggcggccttccacacttctgga
actgcagcccccagcccgggccagacctcctgtcaggccgcctcgctgcctctctcacct
gcctccacaaggcaacaaatagatgagctccgagatgacagcatctgtgacagtggcgtg
gagacatccttccgcaaactcagctttacagagtctctgaccagcggcagctcattgcta
actcttaacaaaatgccccacgagtatgggcaggaaggacctatagaaggcaaaatttag

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