KEGG   Manis javanica (Malayan pangolin): 108391859
Entry
108391859         CDS       T06054                                 

Gene name
TGFBR2
Definition
(RefSeq) TGF-beta receptor type-2 isoform X1
  KO
K04388  TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv04010  MAPK signaling pathway
mjv04060  Cytokine-cytokine receptor interaction
mjv04068  FoxO signaling pathway
mjv04144  Endocytosis
mjv04218  Cellular senescence
mjv04350  TGF-beta signaling pathway
mjv04380  Osteoclast differentiation
mjv04390  Hippo signaling pathway
mjv04520  Adherens junction
mjv04659  Th17 cell differentiation
mjv04926  Relaxin signaling pathway
mjv04933  AGE-RAGE signaling pathway in diabetic complications
mjv05142  Chagas disease
mjv05161  Hepatitis B
mjv05166  Human T-cell leukemia virus 1 infection
mjv05200  Pathways in cancer
mjv05202  Transcriptional misregulation in cancer
mjv05210  Colorectal cancer
mjv05212  Pancreatic cancer
mjv05220  Chronic myeloid leukemia
mjv05225  Hepatocellular carcinoma
mjv05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108391859 (TGFBR2)
   04350 TGF-beta signaling pathway
    108391859 (TGFBR2)
   04390 Hippo signaling pathway
    108391859 (TGFBR2)
   04068 FoxO signaling pathway
    108391859 (TGFBR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    108391859 (TGFBR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    108391859 (TGFBR2)
  09143 Cell growth and death
   04218 Cellular senescence
    108391859 (TGFBR2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    108391859 (TGFBR2)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    108391859 (TGFBR2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    108391859 (TGFBR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108391859 (TGFBR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108391859 (TGFBR2)
   05202 Transcriptional misregulation in cancer
    108391859 (TGFBR2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    108391859 (TGFBR2)
   05212 Pancreatic cancer
    108391859 (TGFBR2)
   05225 Hepatocellular carcinoma
    108391859 (TGFBR2)
   05226 Gastric cancer
    108391859 (TGFBR2)
   05220 Chronic myeloid leukemia
    108391859 (TGFBR2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    108391859 (TGFBR2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108391859 (TGFBR2)
   05161 Hepatitis B
    108391859 (TGFBR2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    108391859 (TGFBR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mjv01001]
    108391859 (TGFBR2)
Enzymes [BR:mjv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     108391859 (TGFBR2)
Protein kinases [BR:mjv01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   108391859 (TGFBR2)
SSDB
Motif
Pfam: ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal APH
Other DBs
NCBI-GeneID: 108391859
NCBI-ProteinID: XP_017507201
LinkDB
Position
Unknown
AA seq 550 aa
MDRIPDLDILLLSPVNNDLMAADSNGAIKFPPLCKFCDVRTSTCDNQKSCLSNCSITAIC
ETPHEVCVAIWRKNDENITLETVCHDPKLTYHGFFLEDAASPKCIMKEKKVSGETFFMCS
CSSDECNDHIIFSEEYTTNSPDLLLVIFQVTGISLLPPLGIAIAVIITFYCYRIHRQQKL
SPAWENSKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAE
VYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTEL
GKQYWLITAFHTKGNLQEYLTRHVISWEDLRRLGGSLARGIAHLHSDHTLCGRPKMPIVH
RDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLE
NVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGR
PEIPSSWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFGELEHLDRLSGRSCSEEKI
PEDGSLNTTK
NT seq 1653 nt   +upstreamnt  +downstreamnt
atggacagaattcctgacctggacatacttctgctttctcctgttaataatgacttgatg
gctgctgacagcaatggcgcaatcaagttcccgcccttgtgtaagttctgcgatgtgagg
acatccacctgtgacaaccagaagtcctgcctgagcaactgcagcatcacagctatctgc
gagacgccgcacgaggtctgcgtggccatctggaggaagaatgatgagaacataacatta
gagacggtttgccatgaccccaaactcacctaccatggattttttctcgaagatgctgct
tctccaaagtgtatcatgaaagaaaaaaaagtgtctggcgagactttctttatgtgctcc
tgtagctctgatgagtgcaatgaccacatcatcttctcggaagaatacactaccaacagc
cccgacttgctgttagtcatattccaagtgacaggcatcagcctgctgcccccgctgggc
atcgccatagctgtcatcatcaccttctactgctaccgcatccaccggcagcagaagctg
agcccagcctgggagaacagcaagcctcggaaactcatggagttcagcgagcaccttgct
atcattctggaagacgaccgctccgacatcagctccacatgtgccaacaacatcaaccac
aacacggagctgctgcccatagagctggacacgctggtggggaaagggcgctttgccgag
gtctacaaggccaagctgaagcagaacacctctgagcagttcgagaccgtggccgtcaag
atcttcccatacgaggagtatgcctcctggaagacggagaaggacattttctcggacatc
aacctgaagcacgagaacattctgcagttcctgacagccgaggagcggaagacagagctg
gggaagcaatactggctgatcaccgccttccacaccaagggcaacctgcaggagtacctg
acgcgccatgtcatcagctgggaggacctgcgcaggctgggcggctccctggctcgcggc
atcgctcacctgcacagcgaccacaccctgtgcgggaggcccaagatgcccatcgtgcac
agggacctcaagagctccaacatcctcgtgaagaatgacctgacctgctgcctctgtgac
ttcgggctctccctgcgtctggaccccactctgtctgtggacgacctggccaacagcggg
caggtgggaactgcaaggtacatggccccagaagtcctagagtccaggatgaatttggag
aacgtggagtcctttaagcagacggatgtctactccatggctctggtgctctgggaaatg
acgtctcgctgtaacgcggtgggagaagtgaaagattatgagccgccatttggttccaag
gtccgggagcacccctgtgtcgaaagcatgaaggataatgtgttgagagatcgtggacga
ccggagatccccagctcctggctcaaccaccagggcatccagatggtgtgcgagaccctg
accgagtgctgggaccatgaccccgaggcccggctcacggcccagtgcgtggccgagcgc
ttcggtgagctggagcacctggacagactgtcagggaggagctgctccgaggagaagatt
cccgaagatggctcactgaacactaccaagtag

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