Manis javanica (Malayan pangolin): 108394490
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Entry
108394490 CDS
T06054
Gene name
MDM2
Definition
(RefSeq) E3 ubiquitin-protein ligase Mdm2 isoform X1
KO
K06643
E3 ubiquitin-protein ligase Mdm2 [EC:
2.3.2.27
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv01522
Endocrine resistance
mjv01524
Platinum drug resistance
mjv04068
FoxO signaling pathway
mjv04110
Cell cycle
mjv04115
p53 signaling pathway
mjv04120
Ubiquitin mediated proteolysis
mjv04144
Endocytosis
mjv04151
PI3K-Akt signaling pathway
mjv04218
Cellular senescence
mjv04625
C-type lectin receptor signaling pathway
mjv04919
Thyroid hormone signaling pathway
mjv05163
Human cytomegalovirus infection
mjv05165
Human papillomavirus infection
mjv05169
Epstein-Barr virus infection
mjv05200
Pathways in cancer
mjv05202
Transcriptional misregulation in cancer
mjv05203
Viral carcinogenesis
mjv05205
Proteoglycans in cancer
mjv05206
MicroRNAs in cancer
mjv05214
Glioma
mjv05215
Prostate cancer
mjv05218
Melanoma
mjv05219
Bladder cancer
mjv05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
108394490 (MDM2)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
108394490 (MDM2)
04151 PI3K-Akt signaling pathway
108394490 (MDM2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
108394490 (MDM2)
09143 Cell growth and death
04110 Cell cycle
108394490 (MDM2)
04115 p53 signaling pathway
108394490 (MDM2)
04218 Cellular senescence
108394490 (MDM2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
108394490 (MDM2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
108394490 (MDM2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108394490 (MDM2)
05202 Transcriptional misregulation in cancer
108394490 (MDM2)
05206 MicroRNAs in cancer
108394490 (MDM2)
05205 Proteoglycans in cancer
108394490 (MDM2)
05203 Viral carcinogenesis
108394490 (MDM2)
09162 Cancer: specific types
05214 Glioma
108394490 (MDM2)
05220 Chronic myeloid leukemia
108394490 (MDM2)
05218 Melanoma
108394490 (MDM2)
05219 Bladder cancer
108394490 (MDM2)
05215 Prostate cancer
108394490 (MDM2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
108394490 (MDM2)
05169 Epstein-Barr virus infection
108394490 (MDM2)
05165 Human papillomavirus infection
108394490 (MDM2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
108394490 (MDM2)
01522 Endocrine resistance
108394490 (MDM2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mjv04131
]
108394490 (MDM2)
04121 Ubiquitin system [BR:
mjv04121
]
108394490 (MDM2)
Enzymes [BR:
mjv01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
108394490 (MDM2)
Membrane trafficking [BR:
mjv04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
108394490 (MDM2)
Ubiquitin system [BR:
mjv04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
MDM2/MDM4 proteins
108394490 (MDM2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-C3HC4_3
SWIB
zf-RanBP
zf-RING_2
zf-FPG_IleRS
Motif
Other DBs
NCBI-GeneID:
108394490
NCBI-ProteinID:
XP_017511562
LinkDB
All DBs
Position
Unknown
AA seq
491 aa
AA seq
DB search
MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT
SVSENRCHLEGGSDEKDPVQELQEEKPSSSDLVSRPSTSSRRRAISETEECSDELPGERQ
RKRHKSDSISLSFDESLALCVIREICCERSSGSESTGTPSNSDLDAGVSEHSGDWLDQDS
VSDQFSVEFEVESLDSEDYSLSEDGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLA
DYWKCTSCSEMNPPLPPHCNRCWALRENWLPEDKGRDKGKKPEKAKLESSAQAEEGFDVP
DCKKNTVNESREPCVEENDDKITQTSQSQESEDYSQPSTSNSVIYSSQEDVKEFEREDTQ
DKEESVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ
PIQMIVLTYFP
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atgtgcaataccaacatgtctgtgtctactgatggtgctgtaagcacctcacagattcca
gcttcggaacaagagaccctggttaggccaaagccattgcttttgaagttgctaaagtct
gttggtgcacaaaaagacacttatactatgaaagaggttatattttatcttggccagtat
attatgactaaacgattatatgatgagaaacaacagcatattgtatattgttcgaatgat
cttctaggggatttgtttggagtgccaagcttctctgtgaaagagcacaggaaaatatat
acaatgatctacagaaacttggtagtagtcaatcagcaggaatcatcagattcaggcaca
tctgtgagtgaaaacaggtgtcacctcgaaggtgggagtgatgaaaaggaccctgtgcaa
gagctacaggaagagaaaccttcatcttcagatttggtttctagaccatctacctcatct
agaaggagagcaattagtgagacagaagaatgttcagatgaattacctggtgaacgacaa
agaaagcgccacaaatctgatagtatatccctttcctttgatgagagccttgctctgtgt
gtcataagggagatatgttgtgaaagaagcagtggcagtgagtcaacagggactccgtca
aactcggatcttgatgctggtgtaagtgaacattcaggtgattggttggatcaggattca
gtttcagatcagttcagtgtagaatttgaagttgagtctcttgattcagaagattatagc
cttagtgaagatggacaagaactctcagacgaagatgatgaggtatatcgagttactgtg
tatcaggcaggagagagtgatacagattcatttgaagaagatcctgaaatttccttagct
gactattggaagtgtacttcgtgcagtgaaatgaatcctcccctgccaccacattgcaac
agatgttgggcccttcgtgagaattggcttcctgaagacaaaggcagagacaaagggaaa
aagcctgagaaagccaaactagaaagctcagcacaagcagaagagggctttgatgtccct
gattgtaaaaaaaatacagtgaatgagtctagagagccatgtgttgaggaaaatgatgat
aaaatcacacaaacctcccaatcccaagaaagtgaggactattctcagccatcaacttct
aatagtgtcatttatagcagccaagaagatgtcaaagagtttgagagggaagacacacaa
gacaaagaagaaagtgtggaatctagttttcctcttaatgccattgaaccttgtgtgatt
tgccaaggtcgacctaaaaatgggtgcattgttcatggcaaaacgggacatcttatggca
tgtttcacatgtgcaaagaagctaaagaagagaaataagccctgtccagtatgtaggcaa
ccaattcaaatgattgtgctaacttattttccctag
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