KEGG T06054: 108397360

KEGG Orthology (KO) [BR:mjv00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108397360 (PDGFB)
   04014 Ras signaling pathway
    108397360 (PDGFB)
   04015 Rap1 signaling pathway
    108397360 (PDGFB)
   04630 JAK-STAT signaling pathway
    108397360 (PDGFB)
   04020 Calcium signaling pathway
    108397360 (PDGFB)
   04072 Phospholipase D signaling pathway
    108397360 (PDGFB)
   04151 PI3K-Akt signaling pathway
    108397360 (PDGFB)
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108397360 (PDGFB)
   04540 Gap junction
    108397360 (PDGFB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    108397360 (PDGFB)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108397360 (PDGFB)
   05206 MicroRNAs in cancer
    108397360 (PDGFB)
   05231 Choline metabolism in cancer
    108397360 (PDGFB)
  09162 Cancer: specific types
   05214 Glioma
    108397360 (PDGFB)
   05218 Melanoma
    108397360 (PDGFB)
   05211 Renal cell carcinoma
    108397360 (PDGFB)
   05215 Prostate cancer
    108397360 (PDGFB)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    108397360 (PDGFB)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    108397360 (PDGFB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108397360 (PDGFB)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:mjv04052]
    108397360 (PDGFB)
   00536 Glycosaminoglycan binding proteins [BR:mjv00536]
    108397360 (PDGFB)
Cytokines and growth factors [BR:mjv04052]
Growth factors
  Growth factors (RTK binding)
   108397360 (PDGFB)
Glycosaminoglycan binding proteins [BR:mjv00536]
Heparan sulfate / Heparin
  Growth factors/receptors
   108397360 (PDGFB)

SSDB

Motif

Pfam:

PDGF PDGF_N

Other DBs

NCBI-GeneID:

108397360

NCBI-ProteinID:

XP_017516225

LinkDB

Position

Unknown

AA seq 242 aa
MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHAIRSFDDLQRLLHGDSVGEDGAGL
DLNVTRPHSGGELESLPRGRRSLGSPTVAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
WPPCVEVQRCSGCCNNRNVQCRPTQVQLRHVQVRKIEIVRKKPTFKKATVTLEDHLACKC
ETVVAARPVTRSPGNSQDQRAARTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKMALKETL
GA

NT seq 729 nt +upstreamnt +downstreamnt
atgaatcgctgctgggcgctcttcctgtctctctgctgctacctgcgtctggtcagcgcc
gagggggaccccattccagaggagctctatgagatgctgagtgaccacgcaatccgctcc
ttcgatgacctccagcgcctgctgcatggagactccgtaggtgaagacggggctgggctg
gacctaaatgtgacccggccccattctggaggcgagctggagagcttaccccgtgggagg
aggagcctaggttccccgacggttgctgagccagccatgatcgctgagtgcaagacccgc
accgaggtgtttgagatctcccggcgcctcatagaccgcaccaacgccaacttcctggtg
tggccgccctgcgtggaggtgcagcgctgctctggctgctgcaacaaccgcaacgtgcag
tgccgccccacccaggtgcagctgcggcacgttcaggtgagaaagatcgagattgtgcgg
aagaagccgacctttaaaaaggccacggtgaccctggaggaccacttggcgtgcaagtgt
gagacagtggtggctgcacgacccgtgacccgaagcccggggaattcccaggaccagcga
gcagcgaggacgccccaaactcgggtgaccattaggacagtgcgggtccgccgacccccc
aaggggaagcaccggaaattcaagcacacacatgacaagatggcactgaaggagaccctc
ggagcctag

Manis javanica (Malayan pangolin): 108408073

Entry

108408073 CDS T06054

Gene name

EGF

Definition

(RefSeq) pro-epidermal growth factor isoform X1

K04357

epidermal growth factor

Organism

mjv Manis javanica (Malayan pangolin)

Pathway

mjv01521

EGFR tyrosine kinase inhibitor resistance

mjv04010

MAPK signaling pathway

mjv04012

ErbB signaling pathway

mjv04014

Ras signaling pathway

mjv04015

Rap1 signaling pathway

mjv04020

Calcium signaling pathway

mjv04066

HIF-1 signaling pathway

mjv04068

FoxO signaling pathway

mjv04072

Phospholipase D signaling pathway

mjv04151

PI3K-Akt signaling pathway

mjv04510

Focal adhesion

mjv04540

Gap junction

mjv04630

JAK-STAT signaling pathway

mjv04810

Regulation of actin cytoskeleton

mjv05160

Hepatitis C

mjv05165

Human papillomavirus infection

mjv05200

Pathways in cancer

mjv05210

Colorectal cancer

mjv05212

Pancreatic cancer

mjv05213

Endometrial cancer

mjv05214

Glioma

mjv05215

Prostate cancer

mjv05218

Melanoma

mjv05219

Bladder cancer

mjv05223

Non-small cell lung cancer

mjv05224

Breast cancer

mjv05226

Gastric cancer

mjv05231

Choline metabolism in cancer

mjv05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Brite

KEGG Orthology (KO) [BR:mjv00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108408073 (EGF)
   04012 ErbB signaling pathway
    108408073 (EGF)
   04014 Ras signaling pathway
    108408073 (EGF)
   04015 Rap1 signaling pathway
    108408073 (EGF)
   04630 JAK-STAT signaling pathway
    108408073 (EGF)
   04066 HIF-1 signaling pathway
    108408073 (EGF)
   04068 FoxO signaling pathway
    108408073 (EGF)
   04020 Calcium signaling pathway
    108408073 (EGF)
   04072 Phospholipase D signaling pathway
    108408073 (EGF)
   04151 PI3K-Akt signaling pathway
    108408073 (EGF)
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108408073 (EGF)
   04540 Gap junction
    108408073 (EGF)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    108408073 (EGF)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108408073 (EGF)
   05231 Choline metabolism in cancer
    108408073 (EGF)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108408073 (EGF)
  09162 Cancer: specific types
   05210 Colorectal cancer
    108408073 (EGF)
   05212 Pancreatic cancer
    108408073 (EGF)
   05226 Gastric cancer
    108408073 (EGF)
   05214 Glioma
    108408073 (EGF)
   05218 Melanoma
    108408073 (EGF)
   05219 Bladder cancer
    108408073 (EGF)
   05215 Prostate cancer
    108408073 (EGF)
   05213 Endometrial cancer
    108408073 (EGF)
   05224 Breast cancer
    108408073 (EGF)
   05223 Non-small cell lung cancer
    108408073 (EGF)
  09172 Infectious disease: viral
   05160 Hepatitis C
    108408073 (EGF)
   05165 Human papillomavirus infection
    108408073 (EGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108408073 (EGF)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:mjv04052]
    108408073 (EGF)
Cytokines and growth factors [BR:mjv04052]
Growth factors
  Growth factors (RTK binding)
   108408073 (EGF)

SSDB

Motif

Pfam:

Ldl_recept_b FXa_inhibition cEGF EGF_CA EGF DUF5050 EGF_3 SGL hEGF

Other DBs

NCBI-GeneID:

108408073

NCBI-ProteinID:

XP_017533297

LinkDB

Position

Unknown

AA seq 1246 aa
MLLFFIILLPVVFKFTSVSPSALELWNCPDGSPSGNGNSACVDMKIRRDKCWAMELPPGE
ELFSRISAGRGCGGAGPAPFLIFSHGNSIFRIDLEGTNHEQLVANAGISVIMDFHYNKER
LYWVDTERQLLQRVFMNGTRQERVCTIEKNVSGMAVNWINEELIWSNQQEGIITVTDMKG
NNSRVLLSTLKYPANVAVDPVERFIFWCSEEAGSLHRADLSGVAAKVLLETSQKVTAVSL
DVSEKRLFWIQYNREGSKSRLYSCDYDGDSVHFSQHLTQHNLFAMSLFGDRIIYSAWKKK
TIWIANKHTGMDMVRMNLNASSLPPGGVKVVHSLVQPKAEGSATVSDQKQCTLRKGNCRG
SICGRDPKSHSCMCAEGYTLSQDGKYCEDVNECAFWNHGCTLGCENIPGSYYCTCPVGFV
LLPDGKRCHQLISCPSNVSECSHDCVLTSDGPVCFCPEGSVLETDGKMCSGCSSPDNGGC
SQLCLALSPASWECGCFPGYDLQADRKSCTASVGPQPFLLFANSQDIRHMNFDGTDYGTV
LSQQMGKVFALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEAVDVPEGLAVDWSGR
RLYWTDKGKSLIEGSDLTGKHREIIIKEGISQPRGIAVHPVAKRLFWTDMGINPRIESAS
LQGIGRLVIASSDLVWPSGITIDYLTDKLYWCDAKRSVIEMANLDGSKRQRLAQNDVGHP
FAVAVFEDHVWFSDWTMPSVIRVNKRTGKNRVRLRGSMLKPSSLVVVHPLAKPGAEPCFH
RNGGCEHICEERFGTARCSCREGFVKAPDGKMCLAVNGHQISAGNEAGLNNQVTPLDILS
RTGDFGDNITESPPMLVAEIMVSDDDDCGPVGCSRQAQCVSEGADDATCQCLKGFAGDGK
LCSDIDECEVSVTVCPPTSKCINTEGGYVCRCSEGYRGDGIHCLDIDECQLGTHTCGKNS
TCTNTVGNYTCVYSSSLSELGRICPDSTPPSLLGADGHYSVRNSYKECPPSHDGYCLNDG
VCIYIEEVDSYACRCAVGFVGDRCQYRDLRWELRHAGHGRQRNVTVAAACVVALVLMLVL
GLCGAHYYRTQKMLSENLKNPYEESSREESGSRPADSEAGMSSCPQPWFVVLKEHENLRN
GSQPVALKDGQVADVGQLSSLEPGLVQAVSWVKKPQMCMGTEHRHCLPLPSDTGSYPQAV
GCSCRLPSCGAQPTAVEVGKPHFLLSANPSWQQRPLDPPHQMEPTQ

NT seq 3741 nt +upstreamnt +downstreamnt
atgctgctcttctttatcattctgttgcctgtagtttttaagtttacttccgtcagtccc
tcagcactggagctctggaactgtcctgatggctctccctcggggaatgggaattctgct
tgtgtggacatgaagatccgcagagacaagtgctgggctatggagctaccacctggagag
gagctgttttcccgtatctcggccggaaggggctgtggaggcgcaggtcctgcacccttc
ttaattttctcccatggaaacagtatcttcagaattgacctggaaggaactaatcatgag
caattagtggcaaatgctggcatatcggtgatcatggattttcattacaataaggaaaga
ctctattgggtagatacagaaagacagcttctacagagagtttttatgaatgggacaagg
caagagagagtatgcactatagagaaaaatgtttcaggaatggcagtaaattggataaat
gaggaacttatttggtcaaatcaacaagaaggaatcattactgtaacagatatgaaagga
aacaattcccgtgttctcttaagtactttgaaatatcctgcaaatgtagcagttgatcca
gtagaaaggtttatattttggtgttcggaggaggccggcagccttcacagagcagatctc
agtggtgtggccgcgaaggttctgttggagacgtcacagaaagtaactgccgtgtcattg
gatgtgtccgagaaacggctcttttggattcagtataacagagagggaagcaaatctcgt
ctgtattcctgtgattatgatggcgattctgtccatttcagccaacatcttacacagcac
aatttgtttgcgatgtccctttttggtgaccgtataatctattcagcatggaaaaagaag
acgatttggatagctaacaagcacactgggatggatatggttagaatgaacctcaatgca
tcatctttaccccctggtggagttaaagtagtgcattccctcgtacagcccaaggcagag
ggcagtgctacagtgtctgatcagaaacagtgcacactgaggaaaggtaactgcagaggc
agcatatgtgggcgagaccccaagtcccactcgtgcatgtgtgcagagggatatacttta
agccaagatggaaagtactgtgaagatgtcaatgaatgtgccttttggaatcatggctgt
actcttgggtgtgaaaacatccctggatcctattattgcacatgtcctgtgggatttgtt
ctgcttcctgatgggaaacggtgtcaccaattaatttcctgtccaagcaatgtgtctgaa
tgcagccatgactgtgtgctgacctcagacggtcctgtatgcttctgtcctgaaggctca
gtgcttgagacagatggaaagatgtgtagtggctgttcctctcctgacaacggtggctgc
agccagctctgcctcgctctcagcccagcatcctgggaatgtggctgctttcctgggtat
gacctgcaggcggaccggaaaagctgtacagcctcagtaggaccacagccgtttttgctg
tttgccaattctcaagatattcgacacatgaactttgatggaacagattatggaactgtg
ctgagccagcaaatgggaaaggtttttgccctagatcatgaccctgtggaaaacaagata
tactttgcccacacagccctgaagtggatagagagagctaatatggatggttcccagcga
gaaaggcttattgaagccgtagatgtgccagaaggtcttgctgtagactggagtggccgc
agattgtactggacagacaaagggaagtctctcattgaagggagtgatttaactggaaaa
catcgtgaaataatcattaaggaaggcatctctcagccacgaggaattgctgttcatcca
gtggccaagagattattctggactgatatggggattaatccacgaattgaaagtgcttcc
cttcaaggcattggccggctggttatagctagctctgatctggtgtggcccagtggaata
acgattgattacttaactgacaagttgtattggtgtgatgccaaacggtctgtgatagaa
atggccaatctggatggttccaaacgccaaagacttgctcaaaacgatgtaggtcatcca
ttcgctgtagctgtgtttgaggatcacgtgtggttctctgattggactatgccatcggta
ataagggtgaacaagaggacaggcaaaaacagggtacgtctccgaggcagcatgctgaag
ccctcatcactggttgtagttcatcctttggcaaaaccaggagcagagccgtgcttccat
cggaatggaggctgtgaacatatttgtgaagagaggtttggaactgctcggtgttcatgt
cgtgaaggttttgtaaaagccccagatgggaaaatgtgcctggctgtgaatggccatcag
atatcagcaggtaatgaagcaggtctaaataatcaagtaacaccattggacatcttatcc
aggacaggagactttggtgataacatcacagagtctccacctatgctggtggctgaaatc
atggtgtcagatgatgacgactgtggtcctgtgggatgcagcaggcaggcgcagtgtgtt
tcagagggtgcagatgatgccacgtgtcagtgtctgaaaggatttgctggggatggaaaa
ctatgttctgatatagatgagtgtgaggtgagtgtcacagtttgccctcccacctccaag
tgcatcaatactgaaggtggctacgtttgccggtgctcagaaggctaccgaggagatggg
attcactgtctggatattgatgaatgccaactgggcacgcacacctgtgggaaaaattcc
acctgtacaaatacagtgggaaactacacctgcgtgtactctagcagcctgtctgaactg
ggacggatttgcccggactctactccaccctctcttttaggggcggatggccactattct
gtgagaaatagttacaaggaatgtcccccatctcatgacgggtactgcctcaatgatggt
gtgtgcatatacattgaggaagttgacagctatgcatgcaggtgcgccgtaggcttcgtc
ggggaccgctgccagtaccgagacctgaggtgggagctgcgccacgccggccacgggcgg
cagaggaacgtcacggtggcggccgcctgcgtggtggcactggtcctgatgctggtcctg
gggctgtgtggggcccattactacaggactcagaagatgctatcagaaaatctgaagaat
ccttatgaagagtcaagcagagaagagagcggtagcaggcctgcagacagtgaggctggg
atgtcctcttgcccccaaccttggtttgtggttttaaaggaacacgagaacctcaggaat
gggagtcaacctgtggccctcaaagatggtcaggtggcagatgttggccagctttcctcc
ctggagcctgggttagtgcaagcggtgtcctgggtgaagaagccccagatgtgcatgggc
acagagcacagacactgccttccgctgcccagtgatacaggctcctatccacaagcagtg
gggtgtagctgccgtcttccctcctgtggggcacagcccactgctgtggaagttgggaag
ccacattttcttctgtcagctaacccatcatggcaacaaaggcccctggatccaccacac
caaatggagccgactcaatga

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