KEGG   Manis javanica (Malayan pangolin): 108397369
Entry
108397369         CDS       T06054                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv04010  MAPK signaling pathway
mjv04022  cGMP-PKG signaling pathway
mjv04137  Mitophagy - animal
mjv04141  Protein processing in endoplasmic reticulum
mjv04151  PI3K-Akt signaling pathway
mjv04210  Apoptosis
mjv04211  Longevity regulating pathway
mjv04261  Adrenergic signaling in cardiomyocytes
mjv04668  TNF signaling pathway
mjv04720  Long-term potentiation
mjv04722  Neurotrophin signaling pathway
mjv04725  Cholinergic synapse
mjv04728  Dopaminergic synapse
mjv04911  Insulin secretion
mjv04912  GnRH signaling pathway
mjv04915  Estrogen signaling pathway
mjv04918  Thyroid hormone synthesis
mjv04922  Glucagon signaling pathway
mjv04925  Aldosterone synthesis and secretion
mjv04926  Relaxin signaling pathway
mjv04927  Cortisol synthesis and secretion
mjv04928  Parathyroid hormone synthesis, secretion and action
mjv04932  Non-alcoholic fatty liver disease
mjv04934  Cushing syndrome
mjv04935  Growth hormone synthesis, secretion and action
mjv05010  Alzheimer disease
mjv05012  Parkinson disease
mjv05014  Amyotrophic lateral sclerosis
mjv05020  Prion disease
mjv05022  Pathways of neurodegeneration - multiple diseases
mjv05030  Cocaine addiction
mjv05031  Amphetamine addiction
mjv05034  Alcoholism
mjv05161  Hepatitis B
mjv05163  Human cytomegalovirus infection
mjv05166  Human T-cell leukemia virus 1 infection
mjv05203  Viral carcinogenesis
mjv05207  Chemical carcinogenesis - receptor activation
mjv05215  Prostate cancer
mjv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    108397369 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108397369 (ATF4)
   04668 TNF signaling pathway
    108397369 (ATF4)
   04022 cGMP-PKG signaling pathway
    108397369 (ATF4)
   04151 PI3K-Akt signaling pathway
    108397369 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    108397369 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    108397369 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    108397369 (ATF4)
   04922 Glucagon signaling pathway
    108397369 (ATF4)
   04912 GnRH signaling pathway
    108397369 (ATF4)
   04915 Estrogen signaling pathway
    108397369 (ATF4)
   04926 Relaxin signaling pathway
    108397369 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    108397369 (ATF4)
   04918 Thyroid hormone synthesis
    108397369 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    108397369 (ATF4)
   04925 Aldosterone synthesis and secretion
    108397369 (ATF4)
   04927 Cortisol synthesis and secretion
    108397369 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108397369 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    108397369 (ATF4)
   04728 Dopaminergic synapse
    108397369 (ATF4)
   04720 Long-term potentiation
    108397369 (ATF4)
   04722 Neurotrophin signaling pathway
    108397369 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    108397369 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    108397369 (ATF4)
   05203 Viral carcinogenesis
    108397369 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    108397369 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108397369 (ATF4)
   05161 Hepatitis B
    108397369 (ATF4)
   05163 Human cytomegalovirus infection
    108397369 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108397369 (ATF4)
   05012 Parkinson disease
    108397369 (ATF4)
   05014 Amyotrophic lateral sclerosis
    108397369 (ATF4)
   05020 Prion disease
    108397369 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    108397369 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    108397369 (ATF4)
   05031 Amphetamine addiction
    108397369 (ATF4)
   05034 Alcoholism
    108397369 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108397369 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    108397369 (ATF4)
   04934 Cushing syndrome
    108397369 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mjv03000]
    108397369 (ATF4)
Transcription factors [BR:mjv03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    108397369 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 Laminin_II DUF3450 AAA_13 Nop53 bZIP_Maf
Other DBs
NCBI-GeneID: 108397369
NCBI-ProteinID: XP_017516243
LinkDB
Position
Unknown
AA seq 353 aa
MAEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPYGFSGDKAKAGSSE
WLAVDGLTNVSDNSKEDAFSGTDWMVEKMDLKEFDFDSLLNMDDLETMPDELLATLDDDT
CDLFDPLVQETNKEPPQTVNPIGHLPESLPESDQIAPLTFLQPLPLSPGTLPSTPDHSFS
LDLGSEVDISEGDRKPDSTDYIATIPQCIKEEDAPSDNDSGICMSPEPYLSSPQHSPSTS
RGSPSKGLLSPGVLSGTPRPKPYDLPGERVAASKVKGEKLDKKLKKMEQNKTAATRYRQK
KRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKKVP
NT seq 1062 nt   +upstreamnt  +downstreamnt
atggccgagatgagcttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaagaaagcctaggcctcttagacgactacctggaggtg
gccaagcacttcaaaccttatgggttctctggtgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttgaccaatgtctcagataacagcaaggaggatgccttctcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgattcgctgttg
aatatggatgatctggaaaccatgccagatgagcttttggccacgttggatgatgacacg
tgtgatctctttgaccccctagtccaggagactaataaggagcccccccagacagtgaac
ccaattggccatctcccagagagtttaccagaatcagatcagattgcccccttaactttc
ctgcaacctcttcccctatccccgggtaccctgccctccactccagaccattcctttagt
ttagacctaggcagtgaagtggatatctctgagggagataggaagccagactcgaccgat
tatattgccacaatccctcagtgcataaaggaggaggatgccccctcagataatgacagt
ggtatctgtatgagcccagagccctatttgagctcgccccagcatagcccctctacctcc
aggggctccccaagtaagggcctattgtctccaggtgtcttgtctggcaccccccgcccc
aaaccctatgaccttcctggggagagggtggcggcatcaaaagtaaaaggtgaaaaactg
gataagaagctgaaaaagatggagcagaacaagacagcagccactaggtaccgccaaaag
aagagggcagagcaggaggcgctcactggggagtgtaaagaactagaaaagaagaatgag
gctctgaaagagagggcagattccttggccaaggagatccagtatctgaaagatttgata
gaggaggtccgcaaagcaagggggaagaagaaagtcccctag

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