Manis javanica (Malayan pangolin): 108398898 Help Entry 108398898         CDS       T06054                                  Gene name CASP8 Definition (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism mjv  Manis javanica (Malayan pangolin) Pathway mjv01524   Platinum drug resistance mjv04115   p53 signaling pathway mjv04210   Apoptosis mjv04215   Apoptosis - multiple species mjv04217   Necroptosis mjv04620   Toll-like receptor signaling pathway mjv04621   NOD-like receptor signaling pathway mjv04622   RIG-I-like receptor signaling pathway mjv04625   C-type lectin receptor signaling pathway mjv04657   IL-17 signaling pathway mjv04668   TNF signaling pathway mjv04932   Non-alcoholic fatty liver disease mjv05010   Alzheimer disease mjv05016   Huntington disease mjv05022   Pathways of neurodegeneration - multiple diseases mjv05132   Salmonella infection mjv05134   Legionellosis mjv05142   Chagas disease mjv05145   Toxoplasmosis mjv05152   Tuberculosis mjv05160   Hepatitis C mjv05161   Hepatitis B mjv05162   Measles mjv05163   Human cytomegalovirus infection mjv05164   Influenza A mjv05165   Human papillomavirus infection mjv05167   Kaposi sarcoma-associated herpesvirus infection mjv05168   Herpes simplex virus 1 infection mjv05169   Epstein-Barr virus infection mjv05170   Human immunodeficiency virus 1 infection mjv05200   Pathways in cancer mjv05203   Viral carcinogenesis mjv05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:mjv00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     108398898 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     108398898 (CASP8)    04215 Apoptosis - multiple species     108398898 (CASP8)    04217 Necroptosis     108398898 (CASP8)    04115 p53 signaling pathway     108398898 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     108398898 (CASP8)    04621 NOD-like receptor signaling pathway     108398898 (CASP8)    04622 RIG-I-like receptor signaling pathway     108398898 (CASP8)    04625 C-type lectin receptor signaling pathway     108398898 (CASP8)    04657 IL-17 signaling pathway     108398898 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     108398898 (CASP8)    05203 Viral carcinogenesis     108398898 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     108398898 (CASP8)    05016 Huntington disease     108398898 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     108398898 (CASP8)   09166 Cardiovascular disease    05416 Viral myocarditis     108398898 (CASP8)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     108398898 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     108398898 (CASP8)    05134 Legionellosis     108398898 (CASP8)    05152 Tuberculosis     108398898 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     108398898 (CASP8)    05161 Hepatitis B     108398898 (CASP8)    05160 Hepatitis C     108398898 (CASP8)    05164 Influenza A     108398898 (CASP8)    05162 Measles     108398898 (CASP8)    05168 Herpes simplex virus 1 infection     108398898 (CASP8)    05163 Human cytomegalovirus infection     108398898 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     108398898 (CASP8)    05169 Epstein-Barr virus infection     108398898 (CASP8)    05165 Human papillomavirus infection     108398898 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     108398898 (CASP8)    05142 Chagas disease     108398898 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     108398898 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mjv01002]     108398898 (CASP8) Enzymes [BR:mjv01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      108398898 (CASP8) Peptidases and inhibitors [BR:mjv01002]  Cysteine peptidases   Family C14: caspase family    108398898 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED Dynamin_N PYRIN Motif Other DBs NCBI-GeneID:  108398898 NCBI-ProteinID:  XP_017518745 LinkDB All DBs Position Unknown AA seq 383 aa AA seqDB search MLFQISEDVSKLELRSFKFLLSQKISKCKLDDDMNMLDIFTEMEKRVILGERNLDTLRKI CDQVNKSLLKKINDYEELSRERRTSLEKSPDELSNDLSQFFMKEKLFEELPMLDSPGVPD SESQVSIEVYPMKSKPRGYCLIFNNYDFSIARKDVPKLQSIKDRNGTHLDAEALSKTFSD LHFEIVCYKDSTAKEICEILKSYQKMDHNNRDCFICCILSHGDKGIIYGSDGQEAPIYEL TSYFTGLRCPSLAGKPKIFFIQACQGDNFQRGIAVETDSKQKEDCLEMDSSFRKKYIPDE ADFLLGMATVNNYVSYRNPMEGTWYIQSLCQSLRERCPRGEDILAILTKVNFEVSNKDDR KNMGKQMPQPTFTLRKKLFFPLH NT seq 1152 nt NT seq  +upstreamnt  +downstreamnt atgctttttcagatttcagaagatgtaagcaaactggaattgaggtcctttaagttcctt ttgagccagaagatttccaaatgtaaactggatgatgacatgaacatgcttgacattttc acagagatggagaagagggttattctaggggaaagaaatttggataccctaagaaaaatc tgtgaccaagtcaacaagagtctgctgaagaaaatcaatgactatgaagaattgagcaga gaaagaagaacgagccttgaaaaaagtccagatgaactttccaatgatctgtctcaattt ttcatgaaggaaaaattatttgaagagctgccaatgttagactctccaggagtacccgac agtgagtcccaggtatcaatcgaagtttacccgatgaaaagcaaaccacgaggttattgt ttaatcttcaacaattatgattttagtatagcacgaaaggatgtacccaaacttcagagc attaaggacaggaatggaacacacttggatgcagaggctttgagtaagacctttagtgat ctccattttgagatagtgtgttacaaagactccacagcaaaggaaatctgtgagattctg aaatcctaccaaaagatggaccacaataacagggactgcttcatctgctgcatcctctcc catggagacaaaggaatcatctatggctctgatgggcaggaagcccccatctatgagctg acctcttacttcactggtttgcggtgcccatcccttgcaggcaaacccaaaatatttttt attcaggcctgtcaaggggataacttccagagaggtatagctgttgagactgactcaaaa cagaaggaagactgtttagaaatggactcatcatttcggaagaaatacattccagatgag gctgactttctgttggggatggccactgtgaacaactatgtttcctaccgaaaccccatg gaggggacctggtatatccagtcactttgccagagcctgagagaaagatgtcctaggggt gaagacattctcgccatcctgaccaaagtgaacttcgaagtaagcaacaaggatgacagg aaaaacatggggaaacaaatgccacaacccactttcacactgagaaaaaagctcttcttc cctcttcattga

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