Manis javanica (Malayan pangolin): 108401094
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Entry
108401094 CDS
T06054
Gene name
MAP3K5
Definition
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv01524
Platinum drug resistance
mjv04010
MAPK signaling pathway
mjv04071
Sphingolipid signaling pathway
mjv04141
Protein processing in endoplasmic reticulum
mjv04210
Apoptosis
mjv04530
Tight junction
mjv04668
TNF signaling pathway
mjv04714
Thermogenesis
mjv04722
Neurotrophin signaling pathway
mjv04932
Non-alcoholic fatty liver disease
mjv05010
Alzheimer disease
mjv05012
Parkinson disease
mjv05014
Amyotrophic lateral sclerosis
mjv05016
Huntington disease
mjv05017
Spinocerebellar ataxia
mjv05022
Pathways of neurodegeneration - multiple diseases
mjv05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
108401094 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108401094 (MAP3K5)
04668 TNF signaling pathway
108401094 (MAP3K5)
04071 Sphingolipid signaling pathway
108401094 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
108401094 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
108401094 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
108401094 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
108401094 (MAP3K5)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
108401094 (MAP3K5)
05012 Parkinson disease
108401094 (MAP3K5)
05014 Amyotrophic lateral sclerosis
108401094 (MAP3K5)
05016 Huntington disease
108401094 (MAP3K5)
05017 Spinocerebellar ataxia
108401094 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
108401094 (MAP3K5)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
108401094 (MAP3K5)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
108401094 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
108401094 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108401094 (MAP3K5)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
108401094 (MAP3K5)
Protein kinases [BR:
mjv01001
]
Serine/threonine kinases: STE group
STE11 family
108401094 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF4071
Pkinase
ASK_PH
PK_Tyr_Ser-Thr
FPP
Pkinase_fungal
Kinase-like
Motif
Other DBs
NCBI-GeneID:
108401094
NCBI-ProteinID:
XP_017522321
LinkDB
All DBs
Position
Unknown
AA seq
1577 aa
AA seq
DB search
MVSLGRTEADSSWGKLVILTTGKIPRHSEILAAPYFARPKRLSAAPDPSPLRHAGLRALR
LSSVARRASPRPEGGAAAAGNAAKVSRTSSIDQSIRKRDFFLVCPVVALRSERLLTSGLL
GGGPGWRRRSTWPHAEVRELPRGRYRPGPGFPAAPSPGAGPDSRCRDEWAARNRWHAGRA
AARNGDFSGEAGSGRGGRGDRKRNGAGEEEEIEPMKGSCRRGGRRILSAAAAAFPGRSPG
SRPACEVLASPPPPGSLWNLESAAAPGAGLPAASSGSSATRCRGISGGGGGRRTTVAYVI
NEESQGQLVMAESEALQSLREACETVGAALETLHFGKLDFGETAVLDRFYNADIAVVEMS
DAFRQPSLFYHLGVRESFSMANNIILYCDNNSDSLQSLKEIICQKNTMCTGNYTFVPYMI
TPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESIL
NDIRKARNLYTGKELAAELARIRQRVDNTEVLTADIVINLLLSYRDIQDYDSIVKLVETL
EKLPTFDLASHHHVKFHYAFALNRRNLPGDRSKALDVMIPLVQSEEQVASDMYCLVGRIY
KDMFLDSNFMDTESRDHGASWFKKAFESEPSLQSGINYAVLLLAAGHQFESSFELRKVGV
KLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVET
ILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSI
NNEVEEKTISIWHVLPDDKKGIHEWNFSASSIRGVSISKFEERCCFLYVLHNSDDFQIYF
CTELHCKKFFEMVNTITEEKGRSTEEGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAG
RDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHRNIVQYLGSFSENGFIKIFMEQV
PGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGV
LKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATG
KPPFYELGEPQAAMFKVGMFKVHPEIPESMSEEAKAFILKCFEPDPDKRACANDLLIDEF
LKVSSKKKKTQPKLSALSAGSNEYLRSISLPVPVLVEDASSSSEYGSVSPDTELKVDPFN
FKTRAKSCGEKDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRI
LTEDQDKVVRNLMETLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLEL
DFDSHGISQVQMVLFSFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPH
FSLASESDTADQEDLDAEDDHEEHPSNQTVRRPPAVIEDAVATSGVSTLSSTVSHDSQSA
HRSLNVQLGRMKIETNRLLEELIQKEKELQAFLHQAIEEKEQEIKNLKLKSQPIDIPGLP
VCHLSSPDTNTEGSELTDWLRENGADEDTISQFLAEDYSLVDVLYYVTRDDLKCLRLRGG
MLCTLWKAITDFRDKQT
NT seq
4734 nt
NT seq
+upstream
nt +downstream
nt
atggtctctctgggaaggacagaggctgattccagctggggtaaactggtgatcctgacc
acgggaaaaattccaaggcattctgagatattagctgctccttactttgcaaggcccaag
cgcctcagcgctgctccagatccttcccccttgcgccacgcgggcctccgggcgctgcgt
ctttccagcgtcgcacgccgtgccagcccgaggccggaagggggcgccgcggccgcgggg
aacgccgcgaaggtctcgcggaccagctccatagaccagagtattcgcaagagagacttt
tttttggtctgtcctgtcgtcgcgttgcgctccgagcgtttgcttacttcaggtcttctt
ggtggggggcctggttggcggcggcggagcacttggccccacgctgaggtccgggagctg
ccgcgcggtcggtaccgtcccggcccgggcttcccagcagcgccctcccccggggcgggc
cctgactctcggtgccgcgacgagtgggcggcaagaaaccggtggcacgccgggcgagcg
gctgcgagaaacggcgactttagcggcgaggctggctctggacgaggcggccgcggcgat
cggaagagaaacggggccggggaggaggaggaaatagagccgatgaaggggagctgccgc
cgaggagggaggaggatcctttcggctgcagcggccgcctttccgggacgcagcccgggg
agtcggcctgcctgtgaggtgctcgccagcccgccgccgccgggcagcttgtggaacctg
gagagtgccgccgctcctggcgccgggttaccagctgcctcctccgggagcagcgccacc
cggtgccggggcatctccgggggcggaggcggccgacgcaccacggtggcttacgtgatt
aacgaagagagccaagggcagctggtgatggccgagagcgaggctctgcagagcctgcgg
gaggcgtgcgagacggtgggcgccgccttggagaccctgcattttggtaaactggacttc
ggggaaaccgcggtgctggaccgtttttacaatgcagatattgctgtggtggagatgagt
gatgccttcaggcagccttctttgttttaccacctgggagtgagagaaagtttcagcatg
gccaataacatcatcctctactgtgacaataattcagactctcttcagtcgctgaaggaa
atcatttgccagaagaatactatgtgcactgggaactacacgtttgttccttacatgata
actccacacaacaaggtctactgctgtgacagcagcttcatgaaggggttgacagagctc
atgcaaccaaacttcgagctgctgctcggacccatctgcttaccacttgtggaccgtttc
attcagcttctgaaggtggcacaagcaagttccagccagtatttccgggaatctatactc
aatgatatccggaaagctcgtaatttatacactggtaaagaactggcagctgaattggca
agaattcgacagcgagtggacaatactgaagtcttgacagcagatattgtcataaatctg
ttactttcctacagagatatccaggactatgattctattgtgaagctggtagagacttta
gaaaaactgccaacctttgatttggcctctcatcaccatgtgaagtttcattatgcattt
gcactgaacaggagaaatctccctggagataggtcaaaagctcttgatgttatgattcct
ctggtgcaaagtgaagagcaagttgcttcagatatgtactgcttagttggtcgaatctac
aaagatatgtttttggactctaatttcatggacactgaaagtagagaccatggagcttct
tggttcaaaaaggcatttgaatctgagccatcactacagtcaggaattaattatgccgtc
ctccttctggcagctgggcaccagtttgagtcttcctttgagctccggaaagttggggtg
aagctaagtagccttcttggtaaaaagggaaacttagaaaaactccagagctactgggaa
gttggattttttctgggagccagtgtgttggccaatgaccacatgagagttattcaagca
tctgaaaagctttttaaactgaagacaccagcatggtacctcaagtcaattgtagagaca
attttgatatataagcattttgtgaaactgactacagaacagcctgtggccaagcaggaa
cttgtggacttctggatggatttcctggtggaggccacaaagacagatgttactgtagtt
aggtttcctgtattaatattagaaccaaccaaaatctatcaaccttcttatttatctatc
aacaatgaagttgaggagaagacaatatctatttggcacgtgcttcctgatgacaagaaa
ggtatacatgaatggaattttagtgcttcttccatcaggggagtgagtatttctaaattt
gaagaacgatgctgttttctttatgtgcttcataattctgacgatttccagatctatttc
tgtacagaacttcattgcaaaaagttttttgaaatggtgaacaccattactgaagagaag
gggagaagtacagaggaaggagattgtgaaggtgactccctggagtatgactatgaatat
gatgaaaatggtgacagagtcgttttaggaaaaggcacttatgggatagtctatgcaggt
cgggacctgagcaaccaggtcagaattgctatcaaagaaatcccagagagagacagcagg
tactcccagcccctacatgaagaaatagcactgcataagcatctgaagcacagaaatatt
gtccagtatctgggctcttttagtgagaatggtttcattaaaatcttcatggagcaggtc
ccaggaggaagtctttctgctctccttcgttccaaatggggcccactgaaagacaatgag
caaaccattggcttttatacaaagcaaatacttgaaggattaaaatacctccatgacaat
cagatagttcaccgagatataaagggtgacaatgtgttgataaatacctatagtggtgtt
ctcaagatctctgacttcggaacatcaaagagattggctggcataaatccatgtaccgaa
acatttactggtacccttcaatatatggcaccagaaataatcgataaaggaccaagaggc
tacggaaaagcagcggacatttggtctttgggctgcacaatcattgaaatggccacaggg
aaaccacccttttatgaactgggagaaccacaagcagctatgttcaaggtgggaatgttt
aaagtccacccggagatcccagagtccatgtcggaagaggccaaggcattcatactgaaa
tgttttgaaccagatcctgacaagagagcctgtgctaatgacttgcttattgatgagttc
ctaaaggtttcaagcaaaaagaaaaagacacaacctaagctttcagctctctcagctgga
tcaaatgagtatctgaggagcatatccttgcccgtgccggtcctggtggaggatgccagc
agcagcagcgagtatggctcagtctcccccgacacggagctaaaagtggacccattcaat
ttcaaaacaagagccaaatcctgcggagaaaaagacgtaaaaggaatacggacgctcttt
ttgggcattccagatgaaaattttgaagatcatagtgctccaccttccccggaagagaaa
gactctggattctttatgctaaggaaggacagtgaaagacgggccacccttcacaggatc
ctgacggaagaccaagacaaggtcgtgagaaacctaatggaaactttggctcagggggct
gaagaacctaaactaaaatgggagcacatcacaaccctcatcgcaagcctcagagaattt
gtgagatccactgatcgaaaaatcattgccacaacactgtcaaagctgaagttagagctt
gactttgacagccatggcattagtcaagtccaaatggtgctctttagttttcaagatgct
gtcaataaagttcttcggaatcataacatcaagccacactggatgtttgccttagacagt
atcatccgaaaggcagtgcagacagccattaccattctggttccagaactgaggccgcac
ttcagccttgcatctgagagtgatactgctgatcaagaagacttggatgcagaagacgac
catgaggaacacccttcaaaccaaactgtccgaagacctcctgctgtcattgaagatgct
gtggctacctcaggggtgagcacgctcagttccacggtatcccacgattcccagagcgct
caccgatccctgaatgtacagcttggaaggatgaaaatagaaactaatagattgttggaa
gaattgattcagaaagagaaagaattacaagcttttctccatcaagctattgaagaaaaa
gaacaagaaattaaaaacctgaagcttaagtcccaaccaatagatatccccggactgcct
gtgtgtcacctcagttctcctgacacaaacacggaaggttccgaacttactgactggctg
agagaaaatggagctgatgaagacactataagtcagtttctggctgaggattattcacta
gtggatgttctctactatgttacacgtgatgatttaaaatgcctgagactaaggggaggg
atgctatgcacactgtggaaggccatcactgactttcgagacaaacaaacttga
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integrated database retrieval system
