KEGG   Manis javanica (Malayan pangolin): 108405876
Entry
108405876         CDS       T06054                                 

Gene name
MLH1
Definition
(RefSeq) DNA mismatch repair protein Mlh1 isoform X1
  KO
K08734  DNA mismatch repair protein MLH1
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv01524  Platinum drug resistance
mjv03430  Mismatch repair
mjv03460  Fanconi anemia pathway
mjv05200  Pathways in cancer
mjv05210  Colorectal cancer
mjv05213  Endometrial cancer
mjv05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03430 Mismatch repair
    108405876 (MLH1)
   03460 Fanconi anemia pathway
    108405876 (MLH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108405876 (MLH1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    108405876 (MLH1)
   05226 Gastric cancer
    108405876 (MLH1)
   05213 Endometrial cancer
    108405876 (MLH1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    108405876 (MLH1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mjv03400]
    108405876 (MLH1)
DNA repair and recombination proteins [BR:mjv03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    MutL homologs
     108405876 (MLH1)
SSDB
Motif
Pfam: Mlh1_C DNA_mis_repair HATPase_c_3 HATPase_c
Other DBs
NCBI-GeneID: 108405876
NCBI-ProteinID: XP_017529737
LinkDB
Position
Unknown
AA seq 756 aa
MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVVVKEGGLKLIQ
IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLANISTYGFRGEALASISHVAHVTITTKTA
DGKCAYRANYSDGKLKAPPKPCAGNQGTQITVEDLFYNISTRRKALKNPSEEYGKILDVV
GRYSIHNSGISFSVKKQGETVADVRTLPNATTVDNIRSIFGNAVSRELIEVGCEDKTLAF
KMNGYISNANYSVKKCIFLLFINHRLVESSSLRKAIETVYAAYLPKNTHPFLYLSLEISP
QNVDVNVHPTKHEVHFLHEDSILERVQRHIESRLLGANSSRMYFTQTLLPGLAGPSGEVV
KSTAGVTPTSSGSGDKVYAHQMVRTDSREQKLDAFLQPVSKAPSSQPQAVVPENRTDASS
GSTRQQDEEMLELPGPAEVAAENQGLEGDTTKMTSEMSEGKGSPSNPSNPRKRQREGSDV
EMVEDGSRKEMTAACTPRRRIINLTSVLSLQEEINGRGHETLREMLRNHSFVGCVNPQWA
LVQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTE
EDGPKEGLAEYIVEFLKKKAEMLADYFSLEIEEGNLIGLPLLIDNYVPPLEGLPVFILRL
ATEVNWDEEKECFESLSKECAMFYSIRKQYVCEESTLSGQQSEQPGTTPNPWKWTVEHVV
YKAFRSYLLPPKHFTEDGNILQLANLPDLYKVFERC
NT seq 2271 nt   +upstreamnt  +downstreamnt
atgtcgttcgtagcgggggttattcggcggctggacgagacagtagtgaaccgtatcgcg
gcaggggaagttatccagcggccggctaatgccatcaaggagatgattgagaactgttta
gatgcaaaatccaccagtattcaagtggttgttaaagagggaggcctgaagttgattcag
atccaagacaatggcactgggatcaggaaagaagatctggatattgtgtgtgagaggttc
actacaagtaaactgcagtcctttgaggatttagctaacatttctacctatggttttcgg
ggtgaggctttggccagcataagccatgtggctcatgtcactattacaaccaaaacggct
gatgggaagtgtgcatacagagcaaattactcagatggaaagctgaaagcgccccctaaa
ccatgtgcaggcaatcaaggcacccagatcacggtggaggaccttttttacaacatatcc
acgaggaggaaagctttaaaaaatccaagtgaagagtatgggaaaattctggatgttgtt
ggcaggtattcaatacataattcaggcattagtttctcagtaaaaaaacaaggcgagaca
gtagcggacgttagaacactgcccaatgccacaactgtggacaatattcgctccatcttt
ggaaatgctgttagccgagaattgatagaagttgggtgtgaggataaaacccttgccttc
aaaatgaatggttacatatccaatgctaactactcagtgaagaagtgcatcttcttactc
ttcatcaaccatcgtctggtagagtcaagttccttaagaaaagccattgaaacagtgtat
gcagcatatttgcccaaaaacacacacccgttcctgtacctcagcttagaaatcagcccc
cagaatgtggatgtcaacgtgcacccgacgaagcacgaagttcacttcctgcacgaggac
agcatcctggagcgggtgcagcggcacattgagagcaggctgctgggtgccaactcctcc
cgcatgtacttcacccagactttactaccaggtctggctggcccctctggggaggtggtt
aaatccacagcgggtgtgactcccacatcttctggaagtggtgacaaggtttatgcccac
cagatggtccgcacggattcccgggagcagaaactggatgcctttctgcagcctgtgagc
aaggctccatctagtcagccacaggctgttgtcccagagaacaggacagatgcttctagt
ggcagcaccaggcagcaagatgaggaaatgcttgaacttccagggcctgctgaagtggct
gccgagaatcagggcttagaaggggacacaacaaagatgacttcagaaatgtcagagggg
aaagggtccccatccaaccccagcaaccccagaaagagacagcgagaaggctctgatgtg
gaaatggtggaagatggttcccggaaggagatgacagcagcttgtaccccccggagaagg
atcattaacctcactagtgttctgagtctccaggaagaaattaatgggcggggccatgag
actctccgggaaatgctgcgtaaccactcctttgtgggctgtgtgaatcctcagtgggcc
ttggtgcagcatcagaccaagttatacctcctcaacaccaccaaactcagtgaagaactg
ttctaccagatactcatttatgattttgccaattttggtgttctgagattatcggagcct
gcaccactctttgacctcgccatgcttgccttagacagtcctgagagtggctggacggag
gaagatggtcccaaagaaggacttgctgaatacattgttgagtttctgaagaagaaggct
gagatgcttgccgactacttctctttggaaatcgaggaagggaacctgattggattaccc
ctgctgattgacaactatgtgccccctttggagggtctgcctgtcttcattcttcggtta
gccactgaggtgaattgggatgaagaaaaggaatgttttgaaagcctcagtaaagaatgt
gctatgttttactccatccggaagcagtatgtgtgtgaggagtccaccctctcaggccag
cagagtgagcagcctggcaccactccaaacccctggaagtggaccgtggaacatgtcgtc
tataaagccttccgctcataccttctgcctcctaaacacttcacggaggatggtaatatt
ctgcagcttgccaacttgcctgatctgtacaaagtctttgagaggtgctaa

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