Methylocaldum marinum: sS8_4206
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Entry
sS8_4206 CDS
T05638
Name
(GenBank) 2-isopropylmalate synthase 2 (alpha-isopropylmalatesynthase 2) (alpha-ipm synthetase 2) protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mmai
Methylocaldum marinum
Pathway
mmai00290
Valine, leucine and isoleucine biosynthesis
mmai00620
Pyruvate metabolism
mmai01100
Metabolic pathways
mmai01110
Biosynthesis of secondary metabolites
mmai01210
2-Oxocarboxylic acid metabolism
mmai01230
Biosynthesis of amino acids
Module
mmai_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mmai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
sS8_4206
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
sS8_4206
Enzymes [BR:
mmai01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
sS8_4206
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
BBA36136
UniProt:
A0A250KX90
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All DBs
Position
complement(4559557..4561269)
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AA seq
570 aa
AA seq
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MLKQPNTKYRSFPKVQLADRTWPDRVITQAPIWMSTDLRDGNQALFEPMTAERKMRLFKK
LVDIGIKEIEVAFPSASQTEFDFVRTLIDGGHVPADVTIEVLTQAREHLIRRTMASLYGA
RRAIVHVYNATARPFREIVFGMSPDQVIAMAVSSVKLVRELAEAHPKTEWVLEYSPEAFT
GTELEFARDICDAVVEAWGATPERKVILNLPATVEMATPNVYADQIEWMHRNLSRRDDIV
LSVHPHNDRGSAIAAAELALMAGAERVEGCLFGNGERTGNVDLVTLALNLYTQGVDPGLD
FSNINDIARTVEDCIRLPIHPRHPYVGDLVFTAFSGSHQDAIKKGLAHQRPDAFWEVPYL
PIDPADLGRSYDAIIRVNSQSGKGGIAYLLESAYGLSLPRRLQVEFSSVVQRHADATGAE
IMPDELWRMFSEEYLEPATTIRYLEHHLFEHGAAQGMRLMLETNGRRITLMGEGNGPIDA
VVHALGGMVRVQSYEERSMGQGSDARAAAFVEIAIDDIPGIRYGAGIHANIVTASVLAIV
GALNRILNRIEPEAREAVVAMLEKSVRQVA
NT seq
1713 nt
NT seq
+upstream
nt +downstream
nt
atgttgaagcagccgaataccaagtaccgttcctttcccaaggtccaactcgcggaccgt
acctggcccgaccgggtcatcacccaagcccccatctggatgagcaccgatctgcgcgac
ggcaatcaggcgctgttcgagcccatgaccgccgagcgcaagatgaggctgttcaagaag
ctggtggacatcggcatcaaggaaatcgaggtcgccttcccttcggcctcgcaaaccgaa
ttcgacttcgttcgaacgctgatcgacggcggacacgtcccagccgacgtcaccatcgag
gtgctcacccaagcccgcgaacacctgatccggcgcaccatggcatcgctctatggcgcc
cgccgcgcgatcgtccacgtctacaacgccaccgcccggccattccgggaaatcgttttc
ggcatgagccccgaccaggtcatcgcgatggcggtttccagcgtgaagctggtgcgggaa
ctggcggaagcgcatccgaaaaccgaatgggtgctcgaatacagcccggaagccttcacc
ggcaccgaactcgagttcgcccgcgatatttgcgacgcggtggtggaagcctggggcgcc
acgccggagcgcaaggtcatcctcaatctgccggccacggtggagatggcgacgcccaat
gtctatgccgatcagatcgagtggatgcaccggaacctgtcgcggcgcgacgacatcgtt
ctaagcgtgcacccgcacaacgaccgagggtcggccatcgccgccgcggaactcgcgctc
atggccggagccgagcgggtcgagggctgtctgttcggcaacggcgaacggaccggcaac
gtggatttggtgactttggcgctcaatctgtacacccagggcgtcgatcctgggctcgac
ttctcgaacatcaacgacatcgcgcgaaccgtggaagactgcatccgcctgccgatccat
ccgcgccatccttacgtgggcgacctggtattcacagccttttccggctcgcaccaggac
gcgatcaaaaaaggcctggcccaccagcggcccgatgcgttctgggaagtcccctacctg
ccgatagaccccgccgacttgggccgctcctacgacgccatcatccgggtcaacagccag
tccggtaaaggcggcatcgcctatcttctggaatccgcttacggcctgtcgttgccgcgc
cggctccaggtggagttcagcagcgtggtgcagcgccatgccgacgccaccggcgccgaa
atcatgccggacgaactttggcggatgttctcggaggagtatctggaaccggcgacgact
atccgctatctcgagcatcatttgttcgagcacggagcggctcagggcatgcgtctgatg
ctggaaacgaacggccggcggatcacgctgatgggcgaaggcaacggccccattgatgcc
gtggtccacgcactcgggggaatggtgcgggtacagtcctatgaagagcgctccatgggc
caaggctccgacgccagggccgctgccttcgtcgaaatcgcgatcgacgacattcccggc
atccggtacggcgccggcatccacgccaacatcgtcacggcctcggtgctggcgatcgtc
ggcgccctgaaccgcatactcaaccgcatcgaacccgaggcgcgggaagcggttgtcgcc
atgctggaaaagtccgtgcgacaggtcgcttga
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