Mus musculus (mouse): 12005
Entry
12005 CDS
T01002
Gene name
Axin1, AI316800, Axin, Fu, Kb, Ki, fused, kinky, knobbly
Definition
(RefSeq) axin 1
KO
K02157
axin 1
Organism
mmu
Mus musculus (mouse)
Pathway
mmu04310
Wnt signaling pathway
mmu04390
Hippo signaling pathway
mmu04550
Signaling pathways regulating pluripotency of stem cells
mmu04934
Cushing syndrome
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05210
Colorectal cancer
mmu05213
Endometrial cancer
mmu05217
Basal cell carcinoma
mmu05224
Breast cancer
mmu05225
Hepatocellular carcinoma
mmu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
12005 (Axin1)
04390 Hippo signaling pathway
12005 (Axin1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
12005 (Axin1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
12005 (Axin1)
09162 Cancer: specific types
05210 Colorectal cancer
12005 (Axin1)
05225 Hepatocellular carcinoma
12005 (Axin1)
05226 Gastric cancer
12005 (Axin1)
05217 Basal cell carcinoma
12005 (Axin1)
05213 Endometrial cancer
12005 (Axin1)
05224 Breast cancer
12005 (Axin1)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
12005 (Axin1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
12005 (Axin1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mmu01009
]
12005 (Axin1)
Protein phosphatases and associated proteins [BR:
mmu01009
]
Protein Ser/ Thr phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
12005 (Axin1)
SSDB
Motif
Pfam:
DIX
RGS
AXIN1_TNKS_BD
Axin_b-cat_bind
Other DBs
NCBI-GeneID:
12005
NCBI-ProteinID:
NP_033863
MGI:
1096327
Ensembl:
ENSMUSG00000024182
Vega:
OTTMUSG00000026498
UniProt:
O35625
E9QMJ8
LinkDB
Structure
PDB:
3UTM
Position
17 A3.3; 17 13.07 cM
AA seq
868 aa
MQSPKMNVQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSE
TSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEGCADLL
DFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQ
QIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMS
GYLPTLNEDEEWKCDQDADEDDGRDPLPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYG
SWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRRE
MQESIQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKR
VRMEEEGEDGEMPSGPMASHKLPSVPAWHHFPPRYVDMGCSGLRDAHEENPESILDEHVQ
RVMRTPGCQSPGPGHRSPDSGHVAKTAVLGGTASGHGKHVPKLGLKLDTAGLHHHRHVHH
HVHHNSARPKEQMEAEVARRVQSSFSWGPETHGHAKPRSYSENAGTTLSAGDLAFGGKTS
APSKRNTKKAESGKNANAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGSSGLRKQ
QAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRL
EEEEKRANKLPSKQRYVQAVMQRGRTCVRPACAPVLSVVPAVSDLELSETETKSQRKAGG
GSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCG
VVFEEVREDEAVLPVFEEKIIGKVEKVD
NT seq
2607 nt
+upstream
nt +downstream
nt
atgcagagtcccaaaatgaatgtccaggagcagggtttccccttggacctcggagcaagt
ttcaccgaagatgccccccggcccccagtgcctggagaagagggagaactggtatctact
gattcgaggcctgtcaaccacagtttctgttctgggaaaggtaccagcattaaaagtgag
acctcaacagccaccccaagacgttcagatctggatctgggatatgagcccgagggcagt
gcctcccccaccccaccatatttgaggtgggctgagtcactgcattccttactggatgac
caagatgggatcagcctgttcaggactttcctgaagcaggagggctgtgctgacctgctg
gacttctggtttgcctgcagtggcttcaggaagcttgagccctgtgactcaaatgaggaa
aagaggctgaagctggcaagagccatctaccgaaagtacatcctggatagcaatggcatt
gtgtccagacaaaccaagccagccactaagagcttcataaaggactgtgtcatgaagcag
cagatagatcctgccatgtttgaccaggcacagacagaaatccagtccaccatggaggag
aatacctacccttcctttcttaagtctgacatttatttggagtacacaaggacaggctca
gagagtccgaaggtctgcagtgaccagagctcagggtctggaacagggaagggcatgtct
ggatacctgcccactttgaatgaggatgaagaatggaaatgtgaccaagatgcagatgag
gatgatggccgagaccctctcccccccagcaggctcacccagaagctgctattggagact
gctgccccgagggccccctcaagtagacggtacaacgaaggcagagagctcaggtatgga
tcttggagggagcccgtcaacccctactacgtcaactctggctatgccctggccccagcc
accagtgccaatgacagtgagcagcagagcctgtccagtgatgctgacacgctatccctt
acggacagtagtgtggatggaatccccccatacaggatccgtaagcagcaccgaagggag
atgcaggagagtatccaagtcaatgggcgggtacctctacctcacattcctcgcacttac
cgaatgccaaaggagatccgggtagagccacagaaatttgctgaagagcttattcaccgt
ctagaggctgtccagcgcactcgagaggctgaagaaaagttggaggaacggctgaagcgt
gtacgcatggaggaagaaggggaggatggtgaaatgccttctggccccatggcaagtcac
aagctgccttctgtcccagcttggcaccatttcccaccccgctatgtggatatgggctgc
tctggactgcgggatgcccatgaggagaatcctgagagcatcctggatgagcacgtgcaa
agggtcatgaggacacctggctgccagtcacctggcccaggccaccgctctcctgacagt
gggcatgtggctaagactgcagtgctagggggtacagcctccgggcatgggaagcatgtt
cctaagttagggttgaagctggatacagctggcctgcaccatcatagacatgtccaccac
catgttcaccataattcagctagacctaaggagcaaatggaggctgaagttgcccgcagg
gtccagagcagcttctcgtggggcccagaaacacatggtcatgccaagccccggagctat
tccgagaacgcaggcaccaccctcagtgctggggatttggcctttggtggtaaaactagt
gcaccttccaaaagaaacaccaagaaggctgaatctgggaagaatgccaatgctgaggta
cccagtaccacagaggacgctgagaagaaccagaagatcatgcagtggatcattgaggga
gagaaggagatcagtagacaccggaaggcaggccatgggtcttctgggttgaggaagcag
caggcccatgaaagctccaggcccttgtccatcgagcgtcctggggccgtgcacccctgg
gtcagcgctcagcttcggaattctgtccagccttctcatcttttcatccaagatcccaca
atgccacccaatccagcccctaatcccctgacccagctggaagaggcccgcaggcgtttg
gaagaagaagaaaagagagcaaacaaactgccctccaagcagaggtatgtgcaggcagtc
atgcagcggggacgcacctgtgtcaggccagcttgtgcaccggtgctgagtgtggtacca
gccgtgtcggacttggaactctccgagacagagacaaaatcacaaagaaaggcaggtggc
gggagtgcaccaccatgtgacagcattgttgtggcctactatttctgtggggaacccatc
ccctaccggaccctggtgaggggccgtgctgtcaccctgggccagttcaaggagctgcta
accaagaaggggagctacagatactactttaagaaagtgagtgatgagtttgactgtggt
gtggtatttgaggaagtacgggaggatgaggccgtcttgcctgtctttgaagaaaagatc
atcggcaaggtggaaaaggtggactga
Mus musculus (mouse): 12006
Entry
12006 CDS
T01002
Gene name
Axin2, Axi1, Axil, Conductin
Definition
(RefSeq) axin 2
KO
K04385
axin 2
Organism
mmu
Mus musculus (mouse)
Pathway
mmu04310
Wnt signaling pathway
mmu04390
Hippo signaling pathway
mmu04550
Signaling pathways regulating pluripotency of stem cells
mmu04934
Cushing syndrome
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05210
Colorectal cancer
mmu05213
Endometrial cancer
mmu05217
Basal cell carcinoma
mmu05224
Breast cancer
mmu05225
Hepatocellular carcinoma
mmu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
12006 (Axin2)
04390 Hippo signaling pathway
12006 (Axin2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
12006 (Axin2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
12006 (Axin2)
09162 Cancer: specific types
05210 Colorectal cancer
12006 (Axin2)
05225 Hepatocellular carcinoma
12006 (Axin2)
05226 Gastric cancer
12006 (Axin2)
05217 Basal cell carcinoma
12006 (Axin2)
05213 Endometrial cancer
12006 (Axin2)
05224 Breast cancer
12006 (Axin2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
12006 (Axin2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
12006 (Axin2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmu03036
]
12006 (Axin2)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic Type
Centrosome formation and ciliogenesis proteins
Other centriole associated proteins
12006 (Axin2)
SSDB
Motif
Pfam:
DIX
RGS
AXIN1_TNKS_BD
Axin_b-cat_bind
SdrD_B
Other DBs
NCBI-GeneID:
12006
NCBI-ProteinID:
NP_056547
MGI:
1270862
Ensembl:
ENSMUSG00000000142
Vega:
OTTMUSG00000003199
UniProt:
O88566
Q3UQK5
LinkDB
Position
11 E1; 11 71.83 cM
AA seq
840 aa
MSSAVLVTLLPDPSSSFREDAPRPPVPGEEGETPPCQPSVGKVQSTKPMPVSSNARRNED
GLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQM
NLKDTKTLRVAKAIYKRYIENNSVVSKQLKPATKTYIRDGIKKQQIGSVMFDQAQTEIQA
VMEENAYQVFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVLCGYLPTLNEEEEWTCADLK
CKLSPTVVGLSSKTLRATASVRSTETAENGFRSFKRSDPVNPYHVGSGYVFAPATSANDS
ELSSDALTDDSMSMTDSSVDGVPPYRMGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPK
EMTPVEPAAFAAELISRLEKLKLELESRHSLEERLQQIREDEEKEGSEQALSSRDGAPVQ
HPLALLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHQHHHHQQCH
TLLPTGGKLPPVAACPLLGGKSFLTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVRCL
CPGGTDYYCYSKCKSHPKAPEPLPGEQFCGSRGGTLPKRNAKGTEPGLALSARDGGMSSA
AGAPQLPGEEGDRSQDVWQWMLESERQSKSKPHSAQSIRKSYPLESACAAPGERVSRHHL
LGASGHSRSVARAHPFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPQKQRCCVASQQRD
RNHSAAGQAGASPFANPSLAPEDHKEPKKLASVHALQASELVVTYFFCGEEIPYRRMLKA
QSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWDDETVLPMYEGRILGKVERID
NT seq
2523 nt
+upstream
nt +downstream
nt
atgagtagcgccgtgttagtgactctccttccagatcccagcagcagcttccgcgaggat
gctccgcggcccccggttccgggagaagaaggggagaccccaccgtgtcagcctagtgtg
ggcaaggtccagtccaccaaacctatgcccgtttcctctaatgctaggcggaatgaagat
ggactgggggagcccgaggggcgggcctcccccgattcccctttgaccaggtggaccaag
tctttacactccttgttgggtgaccaggatggtgcatacctcttccggactttcctggag
agggagaaatgtgtggatacgctggacttctggtttgcttgtaatgggttcaggcagatg
aacctgaaggataccaaaactttgcgagtggccaaagcaatctataagaggtacattgag
aacaacagcgttgtctccaagcagctgaagcccgccaccaagacctacatacgagatggc
atcaagaagcaacagatcggctcggtcatgtttgaccaggcacagaccgagatccaggca
gtgatggaggaaaatgcctaccaggtgttcttgacttctgacatttacctggaatatgtg
aggagtgggggggaaaacacagcttacatgagtaacgggggactggggagcctaaaggtc
ttatgtggctacctccccaccttgaatgaagaagaggagtggacgtgtgccgacctcaag
tgcaaactctcacccaccgtggttggcttgtccagcaaaactcttcgggccaccgcgagt
gtgagatccacggaaacagctgaaaacggattcaggtccttcaagagaagcgacccagtc
aatccttatcacgtaggttccggctatgtctttgcaccagccaccagcgccaacgacagc
gagttatccagcgacgcactgaccgacgattccatgtccatgacggacagtagcgtagat
ggagtccctccttaccgcatggggagtaagaaacagctccagagagagatgcatcgcagt
gtgaaggccaatggccaagtgtctctacctcattttccgagaacccaccgcctgcccaag
gagatgacgcctgtggaacctgctgccttcgccgccgagctcatctccaggctggagaaa
ctgaaactggagctggaaagccgccatagtctggaggagcggctgcagcagatccgggag
gatgaagaaaaggaggggtctgagcaggccctgagctcacgggatggagcaccggtccag
caccccctggccctcctaccctccggcagctatgaagaggacccacaaaccattttggac
gaccacctctccagggtcctcaagacccccggctgtcaatcccctggtgtgggtcgctat
agcccacggtcccgctcccccgaccaccaccaccagcaccaccaccatcagcagtgtcat
acccttcttccgactgggggcaagctgccccccgtggctgcttgccccctccttggaggc
aagagcttcctgaccaaacagacgacgaagcacgttcaccaccactacatccaccaccac
gctgtccccaagaccaaggaggagatcgaggcagaagccacacagagagtccgctgcctc
tgtcctgggggaacagattattattgctactccaaatgcaaaagccacccaaaggctcca
gagcccctgcctggggagcagttttgtggcagcagaggtggtaccttgccaaaacggaat
gcaaagggcaccgaaccgggtcttgcactgtcggccagggatggagggatgtccagtgca
gcgggggccccccagcttcctggggaagaaggagaccggtcacaggatgtctggcagtgg
atgttagagagtgagcggcagagcaagtccaagccccatagtgcccaaagcataagaaag
agctacccattggagtctgcctgtgcggccccaggagaacgagtcagccggcaccatctg
ttgggggccagcggacactcccgctcggtggcccgggctcacccatttacccaggaccct
gcaatgcctccccttaccccacccaacactttggcacagctagaggaagcctgccgcagg
ctggcagaggtgtcgaagccccagaagcagcggtgctgcgtggccagtcagcagagggac
aggaaccactcggctgctggtcaggcaggagcctcacccttcgccaacccaagcctggct
ccagaagatcacaaagagccaaagaaactggcaagtgtccacgcgctccaggccagtgag
ctggttgtcacctactttttctgtggagaagaaattccatacaggaggatgctgaaggct
caaagcttgaccctgggccacttcaaggagcagctcagcaaaaagggaaattacaggtat
tatttcaagaaggcgagtgacgaatttgcctgcggagcagtttttgaggagatctgggac
gacgagacagtgctccccatgtacgaaggcaggatcctgggcaaagtggagaggatcgac
tga
DBGET
integrated database retrieval system
