Mus musculus (mouse): 12018 Entry 12018             CDS       T01002                                  Gene name Bak1, Bak, N-BAK1, N-Bak Definition (RefSeq) BCL2-antagonist/killer 1   KO K14021   Bcl-2 homologous antagonist/killer Organism mmu  Mus musculus (mouse) Pathway mmu01524   Platinum drug resistance mmu04141   Protein processing in endoplasmic reticulum mmu04210   Apoptosis mmu04215   Apoptosis - multiple species mmu05160   Hepatitis C mmu05162   Measles mmu05163   Human cytomegalovirus infection mmu05164   Influenza A mmu05165   Human papillomavirus infection mmu05167   Kaposi sarcoma-associated herpesvirus infection mmu05168   Herpes simplex virus 1 infection mmu05169   Epstein-Barr virus infection mmu05170   Human immunodeficiency virus 1 infection mmu05200   Pathways in cancer mmu05202   Transcriptional misregulation in cancer mmu05203   Viral carcinogenesis mmu05206   MicroRNAs in cancer mmu05210   Colorectal cancer mmu05212   Pancreatic cancer mmu05213   Endometrial cancer mmu05214   Glioma mmu05216   Thyroid cancer mmu05217   Basal cell carcinoma mmu05218   Melanoma mmu05220   Chronic myeloid leukemia mmu05222   Small cell lung cancer mmu05223   Non-small cell lung cancer mmu05224   Breast cancer mmu05225   Hepatocellular carcinoma mmu05226   Gastric cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     12018 (Bak1)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     12018 (Bak1)    04215 Apoptosis - multiple species     12018 (Bak1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     12018 (Bak1)    05202 Transcriptional misregulation in cancer     12018 (Bak1)    05206 MicroRNAs in cancer     12018 (Bak1)    05203 Viral carcinogenesis     12018 (Bak1)   09162 Cancer: specific types    05210 Colorectal cancer     12018 (Bak1)    05212 Pancreatic cancer     12018 (Bak1)    05225 Hepatocellular carcinoma     12018 (Bak1)    05226 Gastric cancer     12018 (Bak1)    05214 Glioma     12018 (Bak1)    05216 Thyroid cancer     12018 (Bak1)    05220 Chronic myeloid leukemia     12018 (Bak1)    05217 Basal cell carcinoma     12018 (Bak1)    05218 Melanoma     12018 (Bak1)    05213 Endometrial cancer     12018 (Bak1)    05224 Breast cancer     12018 (Bak1)    05222 Small cell lung cancer     12018 (Bak1)    05223 Non-small cell lung cancer     12018 (Bak1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     12018 (Bak1)    05162 Measles     12018 (Bak1)    05164 Influenza A     12018 (Bak1)    05160 Hepatitis C     12018 (Bak1)    05168 Herpes simplex virus 1 infection     12018 (Bak1)    05163 Human cytomegalovirus infection     12018 (Bak1)    05167 Kaposi sarcoma-associated herpesvirus infection     12018 (Bak1)    05169 Epstein-Barr virus infection     12018 (Bak1)    05165 Human papillomavirus infection     12018 (Bak1)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     12018 (Bak1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03029 Mitochondrial biogenesis [BR:mmu03029]     12018 (Bak1)   09183 Protein families: signaling and cellular processes    02000 Transporters [BR:mmu02000]     12018 (Bak1) Mitochondrial biogenesis [BR:mmu03029]  Mitochondrial quality control factors   Mitochondrial dynamics    Fission and Fusion factors     12018 (Bak1) Transporters [BR:mmu02000]  Other transporters   Pores ion channels [TC:1]    12018 (Bak1) SSDB Motif Pfam:  Bcl-2 Other DBs NCBI-GeneID:  12018 NCBI-ProteinID:  NP_031549 MGI:  1097161 Ensembl:  ENSMUSG00000057789 Vega:  OTTMUSG00000030987 UniProt:  O08734 LinkDB Structure PDB:  5FMJ 2VOH Position 17; 17 A3.3 AA seq 209 aa MASGQGPGPPKVGCDESPSPSEQQVAQDTEEVFRSYVFYLHQQEQETQGAAAPANPEMDN LPLEPNSILGQVGRQLALIGDDINRRYDTEFQNLLEQLQPTAGNAYELFTKIASSLFKSG ISWGRVVALLGFGYRLALYVYQRGLTGFLGQVTCFLADIILHHYIARWIAQRGGWVAALN FRRDPILTVMVIFGVVLLGQFVVHRFFRS NT seq 630 nt   +upstreamnt  +downstreamnt atggcatctggacaaggaccaggtcccccgaaggtgggctgcgatgagtccccgtcccct tctgaacagcaggttgcccaggacacagaggaggtctttcgaagctacgttttttacctc caccagcaggaacaggagacccagggggcggccgcccctgccaaccccgagatggacaac ttgcccctggaacccaacagcatcttgggtcaggtgggtcggcagcttgctctcatcgga gatgatattaaccggcgctacgacacagagttccagaatttactagaacagcttcagccc acagccgggaatgcctacgaactcttcaccaagatcgcctccagcctatttaagagtggc atcagctggggccgcgtggtggctctcctgggctttggctaccgtctggccctgtacgtc taccagcgtggtttgaccggcttcctgggccaggtgacctgctttttggctgatatcata ctgcatcattacatcgccagatggatcgcacagagaggcggttgggtggcagccctgaat tttcgtagagaccccatcctgaccgtaatggtgatttttggtgtggttctgttgggccaa ttcgtggtacacagattcttcagatcatga

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