Mus musculus (mouse): 13645
Entry
13645 CDS
T01002
Gene name
Egf, AI790464
Definition
(RefSeq) epidermal growth factor
KO
K04357
epidermal growth factor
Organism
mmu
Mus musculus (mouse)
Pathway
mmu01521
EGFR tyrosine kinase inhibitor resistance
mmu04010
MAPK signaling pathway
mmu04012
ErbB signaling pathway
mmu04014
Ras signaling pathway
mmu04015
Rap1 signaling pathway
mmu04066
HIF-1 signaling pathway
mmu04068
FoxO signaling pathway
mmu04072
Phospholipase D signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu04510
Focal adhesion
mmu04540
Gap junction
mmu04630
Jak-STAT signaling pathway
mmu04810
Regulation of actin cytoskeleton
mmu05160
Hepatitis C
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05210
Colorectal cancer
mmu05212
Pancreatic cancer
mmu05213
Endometrial cancer
mmu05214
Glioma
mmu05215
Prostate cancer
mmu05218
Melanoma
mmu05219
Bladder cancer
mmu05223
Non-small cell lung cancer
mmu05224
Breast cancer
mmu05226
Gastric cancer
mmu05231
Choline metabolism in cancer
mmu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
13645 (Egf)
04015 Rap1 signaling pathway
13645 (Egf)
04010 MAPK signaling pathway
13645 (Egf)
04012 ErbB signaling pathway
13645 (Egf)
04630 Jak-STAT signaling pathway
13645 (Egf)
04066 HIF-1 signaling pathway
13645 (Egf)
04068 FoxO signaling pathway
13645 (Egf)
04072 Phospholipase D signaling pathway
13645 (Egf)
04151 PI3K-Akt signaling pathway
13645 (Egf)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
13645 (Egf)
04540 Gap junction
13645 (Egf)
09142 Cell motility
04810 Regulation of actin cytoskeleton
13645 (Egf)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
13645 (Egf)
05231 Choline metabolism in cancer
13645 (Egf)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
13645 (Egf)
09162 Cancer: specific types
05210 Colorectal cancer
13645 (Egf)
05212 Pancreatic cancer
13645 (Egf)
05226 Gastric cancer
13645 (Egf)
05214 Glioma
13645 (Egf)
05218 Melanoma
13645 (Egf)
05219 Bladder cancer
13645 (Egf)
05215 Prostate cancer
13645 (Egf)
05213 Endometrial cancer
13645 (Egf)
05224 Breast cancer
13645 (Egf)
05223 Non-small cell lung cancer
13645 (Egf)
09172 Infectious disease: viral
05160 Hepatitis C
13645 (Egf)
05165 Human papillomavirus infection
13645 (Egf)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
13645 (Egf)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
mmu04052
]
13645 (Egf)
Cytokines and growth factors [BR:
mmu04052
]
Growth factors
Growth factors (RTK binding)
13645 (Egf)
SSDB
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
EGF_CA
cEGF
EGF
EGF_3
DUF5050
Plasmod_Pvs28
EGF_MSP1_1
hEGF
Tr-sialidase_C
Other DBs
NCBI-GeneID:
13645
NCBI-ProteinID:
NP_034243
MGI:
95290
Ensembl:
ENSMUSG00000028017
Vega:
OTTMUSG00000054128
UniProt:
P01132
Q3UWD7
LinkDB
Structure
PDB:
1A3P
3EGF
1EPG
1EPH
1EPI
1EPJ
1EGF
Position
3 G3; 3 58.5 cM
AA seq
1217 aa
MPWGRRPTWLLLAFLLVFLKISILSVTAWQTGNCQPGPLERSERSGTCAGPAPFLVFSQG
KSISRIDPDGTNHQQLVVDAGISADMDIHYKKERLYWVDVERQVLLRVFLNGTGLEKVCN
VERKVSGLAIDWIDDEVLWVDQQNGVITVTDMTGKNSRVLLSSLKHPSNIAVDPIERLMF
WSSEVTGSLHRAHLKGVDVKTLLETGGISVLTLDVLDKRLFWVQDSGEGSHAYIHSCDYE
GGSVRLIRHQARHSLSSMAFFGDRIFYSVLKSKAIWIANKHTGKDTVRINLHPSFVTPGK
LMVVHPRAQPRTEDAAKDPDPELLKQRGRPCRFGLCERDPKSHSSACAEGYTLSRDRKYC
EDVNECATQNHGCTLGCENTPGSYHCTCPTGFVLLPDGKQCHELVSCPGNVSKCSHGCVL
TSDGPRCICPAGSVLGRDGKTCTGCSSPDNGGCSQICLPLRPGSWECDCFPGYDLQSDRK
SCAASGPQPLLLFANSQDIRHMHFDGTDYKVLLSRQMGMVFALDYDPVESKIYFAQTALK
WIERANMDGSQRERLITEGVDTLEGLALDWIGRRIYWTDSGKSVVGGSDLSGKHHRIIIQ
ERISRPRGIAVHPRARRLFWTDVGMSPRIESASLQGSDRVLIASSNLLEPSGITIDYLTD
TLYWCDTKRSVIEMANLDGSKRRRLIQNDVGHPFSLAVFEDHLWVSDWAIPSVIRVNKRT
GQNRVRLQGSMLKPSSLVVVHPLAKPGADPCLYRNGGCEHICQESLGTARCLCREGFVKA
WDGKMCLPQDYPILSGENADLSKEVTSLSNSTQAEVPDDDGTESSTLVAEIMVSGMNYED
DCGPGGCGSHARCVSDGETAECQCLKGFARDGNLCSDIDECVLARSDCPSTSSRCINTEG
GYVCRCSEGYEGDGISCFDIDECQRGAHNCGENAACTNTEGGYNCTCAGRPSSPGLSCPD
STAPSLLGEDGHHLDRNSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQT
RDLRWWELRHAGYGQKHDIMVVAVCMVALVLLLVLGMWGTYYYRTRKQLSNPPKNPCDEP
SGSVSSSGPNSSSGAAVASCPQPWFVVLEKHQDPKNGSLPADGTNGAVVDAGLSPSLQLG
SVHLTSWRQKPHIDGMGTGQSCWIPPSSDRGPQEIEGNSHLPSYRPVGPEKLHSLQSANG
SCHERAPDLPRQTEPVQ
NT seq
3654 nt
+upstream
nt +downstream
nt
atgccctggggccgaaggccaacctggctgttgctcgccttcctgctggtgtttttaaag
attagcatactcagcgtcacagcatggcagaccgggaactgtcagccaggtcctctcgag
agaagcgagagaagcgggacttgtgccggtcctgcccccttcctagttttctcacaagga
aagagcatctctcggattgacccagatggaacaaatcaccagcaattggtggtggatgct
ggcatctcagcagacatggatattcattataaaaaagagagactctattgggtggatgta
gaaagacaagttttgctaagagttttccttaacgggacaggactagagaaagtgtgcaat
gtagagaggaaggtgtctgggctggccatagactggatagatgatgaagttctctgggta
gaccaacagaacggagtcatcaccgtaacagatatgacagggaaaaattcccgagttctt
ctaagttccttaaaacatccgtcaaatatagcagtggatccaatagagaggttgatgttt
tggtcttcagaggtgaccggcagccttcacagagcacacctcaaaggtgttgatgtaaaa
acactgctggagacagggggaatatcggtgctgactctggatgtcctggacaaacggctc
ttctgggttcaggacagtggcgaaggaagccacgcttacattcattcctgtgattatgag
ggtggctccgtccgtcttatcaggcatcaagcacggcacagtttgtcttcaatggccttt
tttggtgatcggatcttctactcagtgttgaaaagcaaggcgatttggatagccaacaaa
cacacggggaaggacacggtcaggattaacctccatccatcctttgtgacacctggaaaa
ctgatggtagtacaccctcgtgcacagcccaggacagaggacgctgctaaggatcctgac
cccgaacttctcaaacagaggggaagaccatgccgcttcggtctctgtgagcgagacccc
aagtcccactcgagcgcatgcgctgagggctacacgttaagccgagaccggaagtactgc
gaagatgtcaatgaatgtgccactcagaatcacggctgtactcttgggtgtgaaaacacc
cctggatcctatcactgcacatgccccacaggatttgttctgcttcctgatgggaaacaa
tgtcacgaacttgtttcctgcccaggcaacgtatcaaagtgcagtcatggctgtgtcctg
acatcagatggtccccggtgcatctgtcctgcaggttcagtgcttgggagagatgggaag
acttgcactggttgttcatcgcctgacaatggtggatgcagccagatctgtcttcctctc
aggccaggatcctgggaatgtgattgctttcctgggtatgacctacagtcagaccgaaag
agctgtgcagcttcaggaccacagccacttttactgtttgcaaattcccaggacatccga
cacatgcattttgatggaacagactacaaagttctgctcagccggcagatgggaatggtt
tttgccttggattatgaccctgtggaaagcaagatatattttgcacagacagccctgaag
tggatagagagggctaatatggatgggtcccagcgagaaagactgatcacagaaggagta
gatacgcttgaaggtcttgccctggactggattggccggagaatctactggacagacagt
gggaagtctgttgttggagggagcgatctgagcgggaagcatcatcgaataatcatccag
gagagaatctcgaggccgcgaggaatagctgtgcatccaagggccaggagactgttctgg
acggacgtagggatgtctccacggattgaaagcgcttcccttcaaggttccgaccgggtg
ctgatagccagctccaatctactggaacccagtggaatcacgattgactacttaacagac
actttgtactggtgtgacaccaagaggtctgtgattgaaatggccaatctggatggctcc
aaacgccgaagacttatccagaacgacgtaggtcaccccttctctctagccgtgtttgag
gatcacctgtgggtctcggattgggctatcccatcggtaataagggtgaacaagaggact
ggccaaaacagggtacgtcttcaaggcagcatgctgaagccctcgtcactggttgtggtc
catccattggcaaaaccaggtgcagatccctgcttatacaggaatggaggctgtgaacac
atctgccaagagagcctgggcacagctcggtgtttgtgtcgtgaaggttttgtgaaggcc
tgggatgggaaaatgtgtctccctcaggattatccaatcctgtcaggtgaaaatgctgat
cttagtaaagaggtgacatcactgagcaactccactcaggctgaagtaccagacgatgat
gggacagaatcttccacactagtggctgaaatcatggtgtcaggcatgaactatgaagat
gactgtggtcccggggggtgtggaagccatgctcgatgcgtttcagacggagagactgct
gagtgtcagtgtctgaaagggtttgccagggatggaaacctgtgttctgatatagatgag
tgtgtgctggctagatcggactgccccagcacctcgtccaggtgcatcaacactgaaggt
ggctacgtctgcagatgctcagaaggctacgaaggagacgggatctcctgtttcgatatt
gacgagtgccagcggggggcgcacaactgcggtgagaatgccgcctgcaccaacacggag
ggaggctacaactgcacctgcgcaggccgcccatcctcgcccggactgagttgccctgac
tctaccgcaccctctctccttggggaagatggccaccatttggaccgaaatagttatcca
ggatgcccatcctcatatgatggatactgcctcaatggtggcgtgtgcatgcatattgaa
tcactggacagctacacatgcaactgtgttattggctattctggggatcgatgccagact
cgagacctacgatggtgggaactgcgtcatgctggctacgggcagaagcatgacatcatg
gtggtggctgtctgcatggtggcactggtcctgctgctcgtcttggggatgtgggggact
tactactacaggactcggaagcagctatcaaaccccccaaagaacccttgtgatgagcca
agcggaagtgtgagcagcagcggacccaacagcagcagcggggcagctgtggcttcttgt
ccccaaccttggtttgtggtcctagagaaacaccaagaccccaagaatgggagtctgcct
gcggatggtacgaatggtgcagtagtagatgctggcctgtctccctccctgcagctcggg
tcagtgcatctgacttcatggagacagaagccccacatagatggaatgggcacagggcaa
agctgctggattccaccatcaagtgacagaggaccccaggaaatagagggaaactcccac
ctaccctcctacagacctgtggggccggagaagctgcattctctccagtcagctaatgga
tcgtgtcacgaaagggctccagacctgccacggcagacagagccagttcagtag
DBGET
integrated database retrieval system
