Mus musculus (mouse): 13645 Help Entry 13645             CDS       T01002                                  Gene name Egf, AI790464 Definition (RefSeq) epidermal growth factor   KO K04357   epidermal growth factor Organism mmu  Mus musculus (mouse) Pathway mmu01521   EGFR tyrosine kinase inhibitor resistance mmu04010   MAPK signaling pathway mmu04012   ErbB signaling pathway mmu04014   Ras signaling pathway mmu04015   Rap1 signaling pathway mmu04020   Calcium signaling pathway mmu04066   HIF-1 signaling pathway mmu04068   FoxO signaling pathway mmu04072   Phospholipase D signaling pathway mmu04151   PI3K-Akt signaling pathway mmu04510   Focal adhesion mmu04540   Gap junction mmu04630   JAK-STAT signaling pathway mmu04810   Regulation of actin cytoskeleton mmu05160   Hepatitis C mmu05165   Human papillomavirus infection mmu05200   Pathways in cancer mmu05210   Colorectal cancer mmu05212   Pancreatic cancer mmu05213   Endometrial cancer mmu05214   Glioma mmu05215   Prostate cancer mmu05218   Melanoma mmu05219   Bladder cancer mmu05223   Non-small cell lung cancer mmu05224   Breast cancer mmu05226   Gastric cancer mmu05231   Choline metabolism in cancer mmu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     13645 (Egf)    04012 ErbB signaling pathway     13645 (Egf)    04014 Ras signaling pathway     13645 (Egf)    04015 Rap1 signaling pathway     13645 (Egf)    04630 JAK-STAT signaling pathway     13645 (Egf)    04066 HIF-1 signaling pathway     13645 (Egf)    04068 FoxO signaling pathway     13645 (Egf)    04020 Calcium signaling pathway     13645 (Egf)    04072 Phospholipase D signaling pathway     13645 (Egf)    04151 PI3K-Akt signaling pathway     13645 (Egf)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     13645 (Egf)    04540 Gap junction     13645 (Egf)   09142 Cell motility    04810 Regulation of actin cytoskeleton     13645 (Egf)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     13645 (Egf)    05231 Choline metabolism in cancer     13645 (Egf)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     13645 (Egf)   09162 Cancer: specific types    05210 Colorectal cancer     13645 (Egf)    05212 Pancreatic cancer     13645 (Egf)    05226 Gastric cancer     13645 (Egf)    05214 Glioma     13645 (Egf)    05218 Melanoma     13645 (Egf)    05219 Bladder cancer     13645 (Egf)    05215 Prostate cancer     13645 (Egf)    05213 Endometrial cancer     13645 (Egf)    05224 Breast cancer     13645 (Egf)    05223 Non-small cell lung cancer     13645 (Egf)   09172 Infectious disease: viral    05160 Hepatitis C     13645 (Egf)    05165 Human papillomavirus infection     13645 (Egf)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     13645 (Egf)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:mmu04052]     13645 (Egf) Cytokines and growth factors [BR:mmu04052]  Growth factors   Growth factors (RTK binding)    13645 (Egf) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ldl_recept_b FXa_inhibition EGF_CA cEGF EGF EGF_3 DUF5050 SGL Plasmod_Pvs28 EGF_MSP1_1 hEGF Tr-sialidase_C Motif Other DBs NCBI-GeneID:  13645 NCBI-ProteinID:  NP_034243 MGI:  95290 Ensembl:  ENSMUSG00000028017 Vega:  OTTMUSG00000054128 UniProt:  P01132 Q3UWD7 LinkDB All DBs Structure PDB:  1A3P 3EGF 1EPG 1EPH 1EPI 1EPJ 1EGF Thumbnails Position 3 G3; 3 58.5 cM AA seq 1217 aa AA seqDB search MPWGRRPTWLLLAFLLVFLKISILSVTAWQTGNCQPGPLERSERSGTCAGPAPFLVFSQG KSISRIDPDGTNHQQLVVDAGISADMDIHYKKERLYWVDVERQVLLRVFLNGTGLEKVCN VERKVSGLAIDWIDDEVLWVDQQNGVITVTDMTGKNSRVLLSSLKHPSNIAVDPIERLMF WSSEVTGSLHRAHLKGVDVKTLLETGGISVLTLDVLDKRLFWVQDSGEGSHAYIHSCDYE GGSVRLIRHQARHSLSSMAFFGDRIFYSVLKSKAIWIANKHTGKDTVRINLHPSFVTPGK LMVVHPRAQPRTEDAAKDPDPELLKQRGRPCRFGLCERDPKSHSSACAEGYTLSRDRKYC EDVNECATQNHGCTLGCENTPGSYHCTCPTGFVLLPDGKQCHELVSCPGNVSKCSHGCVL TSDGPRCICPAGSVLGRDGKTCTGCSSPDNGGCSQICLPLRPGSWECDCFPGYDLQSDRK SCAASGPQPLLLFANSQDIRHMHFDGTDYKVLLSRQMGMVFALDYDPVESKIYFAQTALK WIERANMDGSQRERLITEGVDTLEGLALDWIGRRIYWTDSGKSVVGGSDLSGKHHRIIIQ ERISRPRGIAVHPRARRLFWTDVGMSPRIESASLQGSDRVLIASSNLLEPSGITIDYLTD TLYWCDTKRSVIEMANLDGSKRRRLIQNDVGHPFSLAVFEDHLWVSDWAIPSVIRVNKRT GQNRVRLQGSMLKPSSLVVVHPLAKPGADPCLYRNGGCEHICQESLGTARCLCREGFVKA WDGKMCLPQDYPILSGENADLSKEVTSLSNSTQAEVPDDDGTESSTLVAEIMVSGMNYED DCGPGGCGSHARCVSDGETAECQCLKGFARDGNLCSDIDECVLARSDCPSTSSRCINTEG GYVCRCSEGYEGDGISCFDIDECQRGAHNCGENAACTNTEGGYNCTCAGRPSSPGLSCPD STAPSLLGEDGHHLDRNSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQT RDLRWWELRHAGYGQKHDIMVVAVCMVALVLLLVLGMWGTYYYRTRKQLSNPPKNPCDEP SGSVSSSGPNSSSGAAVASCPQPWFVVLEKHQDPKNGSLPADGTNGAVVDAGLSPSLQLG SVHLTSWRQKPHIDGMGTGQSCWIPPSSDRGPQEIEGNSHLPSYRPVGPEKLHSLQSANG SCHERAPDLPRQTEPVQ NT seq 3654 nt NT seq  +upstreamnt  +downstreamnt atgccctggggccgaaggccaacctggctgttgctcgccttcctgctggtgtttttaaag attagcatactcagcgtcacagcatggcagaccgggaactgtcagccaggtcctctcgag agaagcgagagaagcgggacttgtgccggtcctgcccccttcctagttttctcacaagga aagagcatctctcggattgacccagatggaacaaatcaccagcaattggtggtggatgct ggcatctcagcagacatggatattcattataaaaaagagagactctattgggtggatgta gaaagacaagttttgctaagagttttccttaacgggacaggactagagaaagtgtgcaat gtagagaggaaggtgtctgggctggccatagactggatagatgatgaagttctctgggta gaccaacagaacggagtcatcaccgtaacagatatgacagggaaaaattcccgagttctt ctaagttccttaaaacatccgtcaaatatagcagtggatccaatagagaggttgatgttt tggtcttcagaggtgaccggcagccttcacagagcacacctcaaaggtgttgatgtaaaa acactgctggagacagggggaatatcggtgctgactctggatgtcctggacaaacggctc ttctgggttcaggacagtggcgaaggaagccacgcttacattcattcctgtgattatgag ggtggctccgtccgtcttatcaggcatcaagcacggcacagtttgtcttcaatggccttt tttggtgatcggatcttctactcagtgttgaaaagcaaggcgatttggatagccaacaaa cacacggggaaggacacggtcaggattaacctccatccatcctttgtgacacctggaaaa ctgatggtagtacaccctcgtgcacagcccaggacagaggacgctgctaaggatcctgac cccgaacttctcaaacagaggggaagaccatgccgcttcggtctctgtgagcgagacccc aagtcccactcgagcgcatgcgctgagggctacacgttaagccgagaccggaagtactgc gaagatgtcaatgaatgtgccactcagaatcacggctgtactcttgggtgtgaaaacacc cctggatcctatcactgcacatgccccacaggatttgttctgcttcctgatgggaaacaa tgtcacgaacttgtttcctgcccaggcaacgtatcaaagtgcagtcatggctgtgtcctg acatcagatggtccccggtgcatctgtcctgcaggttcagtgcttgggagagatgggaag acttgcactggttgttcatcgcctgacaatggtggatgcagccagatctgtcttcctctc aggccaggatcctgggaatgtgattgctttcctgggtatgacctacagtcagaccgaaag agctgtgcagcttcaggaccacagccacttttactgtttgcaaattcccaggacatccga cacatgcattttgatggaacagactacaaagttctgctcagccggcagatgggaatggtt tttgccttggattatgaccctgtggaaagcaagatatattttgcacagacagccctgaag tggatagagagggctaatatggatgggtcccagcgagaaagactgatcacagaaggagta gatacgcttgaaggtcttgccctggactggattggccggagaatctactggacagacagt gggaagtctgttgttggagggagcgatctgagcgggaagcatcatcgaataatcatccag gagagaatctcgaggccgcgaggaatagctgtgcatccaagggccaggagactgttctgg acggacgtagggatgtctccacggattgaaagcgcttcccttcaaggttccgaccgggtg ctgatagccagctccaatctactggaacccagtggaatcacgattgactacttaacagac actttgtactggtgtgacaccaagaggtctgtgattgaaatggccaatctggatggctcc aaacgccgaagacttatccagaacgacgtaggtcaccccttctctctagccgtgtttgag gatcacctgtgggtctcggattgggctatcccatcggtaataagggtgaacaagaggact ggccaaaacagggtacgtcttcaaggcagcatgctgaagccctcgtcactggttgtggtc catccattggcaaaaccaggtgcagatccctgcttatacaggaatggaggctgtgaacac atctgccaagagagcctgggcacagctcggtgtttgtgtcgtgaaggttttgtgaaggcc tgggatgggaaaatgtgtctccctcaggattatccaatcctgtcaggtgaaaatgctgat cttagtaaagaggtgacatcactgagcaactccactcaggctgaagtaccagacgatgat gggacagaatcttccacactagtggctgaaatcatggtgtcaggcatgaactatgaagat gactgtggtcccggggggtgtggaagccatgctcgatgcgtttcagacggagagactgct gagtgtcagtgtctgaaagggtttgccagggatggaaacctgtgttctgatatagatgag tgtgtgctggctagatcggactgccccagcacctcgtccaggtgcatcaacactgaaggt ggctacgtctgcagatgctcagaaggctacgaaggagacgggatctcctgtttcgatatt gacgagtgccagcggggggcgcacaactgcggtgagaatgccgcctgcaccaacacggag ggaggctacaactgcacctgcgcaggccgcccatcctcgcccggactgagttgccctgac tctaccgcaccctctctccttggggaagatggccaccatttggaccgaaatagttatcca ggatgcccatcctcatatgatggatactgcctcaatggtggcgtgtgcatgcatattgaa tcactggacagctacacatgcaactgtgttattggctattctggggatcgatgccagact cgagacctacgatggtgggaactgcgtcatgctggctacgggcagaagcatgacatcatg gtggtggctgtctgcatggtggcactggtcctgctgctcgtcttggggatgtgggggact tactactacaggactcggaagcagctatcaaaccccccaaagaacccttgtgatgagcca agcggaagtgtgagcagcagcggacccaacagcagcagcggggcagctgtggcttcttgt ccccaaccttggtttgtggtcctagagaaacaccaagaccccaagaatgggagtctgcct gcggatggtacgaatggtgcagtagtagatgctggcctgtctccctccctgcagctcggg tcagtgcatctgacttcatggagacagaagccccacatagatggaatgggcacagggcaa agctgctggattccaccatcaagtgacagaggaccccaggaaatagagggaaactcccac ctaccctcctacagacctgtggggccggagaagctgcattctctccagtcagctaatgga tcgtgtcacgaaagggctccagacctgccacggcagacagagccagttcagtag

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