Mus musculus (mouse): 13867
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Entry
13867 CDS
T01002
Gene name
Erbb3, C76256, Erbb, Erbb-, Erbb-3, Erbb3r, HER, Her3
Definition
(RefSeq) erb-b2 receptor tyrosine kinase 3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
mmu
Mus musculus (mouse)
Pathway
mmu01521
EGFR tyrosine kinase inhibitor resistance
mmu04010
MAPK signaling pathway
mmu04012
ErbB signaling pathway
mmu04020
Calcium signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu05205
Proteoglycans in cancer
mmu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
13867 (Erbb3)
04012 ErbB signaling pathway
13867 (Erbb3)
04020 Calcium signaling pathway
13867 (Erbb3)
04151 PI3K-Akt signaling pathway
13867 (Erbb3)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
13867 (Erbb3)
05205 Proteoglycans in cancer
13867 (Erbb3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
13867 (Erbb3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
13867 (Erbb3)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
13867 (Erbb3)
Protein kinases [BR:
mmu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
13867 (Erbb3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
CD34_antigen
APH
SKG6
Motif
Other DBs
NCBI-GeneID:
13867
NCBI-ProteinID:
NP_034283
MGI:
95411
Ensembl:
ENSMUSG00000018166
Vega:
OTTMUSG00000029881
UniProt:
Q61526
LinkDB
All DBs
Position
10 D3; 10 77.1 cM
AA seq
1339 aa
AA seq
DB search
MSAIGTLQVLGFLLSLARGSEMGNSQAVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVKNNG
GNCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCNGRCFGPNPNQCCHDECAGGCSGPQD
TDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQTF
CVRACPADKMEVDKNGLKMCEPCRGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPAEE
RLDIKYNRPLGECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEP
REFVHEAHCFSCHPECQPMEGTSTCNGSGSDACARCAHFRDGPHCVNSCPHGILGAKGPI
YKYPDAQNECRPCHENCTQGCKGPELQDCLGQAEVLMSKPHLVIAVTVGLTVIFLILGGS
FLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVFGT
VHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSS
LQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVML
KSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVW
ELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELA
NEFTRMARDPPRYLVIKRASGPGIPPAAEPSALSTKELQDAELEPDLDLDLDVEVEEEGL
ATTLGSALSLPTGTLTRPRGSQSLLSPSSGYMPMNQSNLGEACLDSAVLGGREQFSRPIS
LHPIPRGRQTSESSEGHVTGSEAELQERVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPV
TPLSPPGLEEEDGNGYVMPDTHLRGTSSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRK
RRGSPARPPRPGSLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDEDYEYM
NRRRGAGGSGGDYAAMGACPAAEQGYEEMRAFQGPGHQAPHVRYARLKTLRSLEATDSAF
DNPDYWHSRLFPKANAQRI
NT seq
4020 nt
NT seq
+upstream
nt +downstream
nt
atgagtgcgattgggactctgcaggtgctgggtttccttctcagcctggcccggggttcc
gagatgggcaactctcaggcagtatgtcctgggactctaaacgggctgagtgtgaccggc
gatgctgacaaccagtaccagacactgtacaaactctatgagaagtgtgaggtggtcatg
ggtaacctggagattgtgcttacgggacacaatgctgatctttccttcctgcaatggatc
cgagaagtgacaggctatgtactggtggccatgaatgaattctctgtactgcccttacct
aacctccgagtggtccggggaacccaggtctacgatgggaagtttgccatctttgtcatg
ttgaactacaataccaactccagccatgctctgcgccagctccggttcactcagcttact
gagattctgttagggggcgtttacattgagaagaatgacaaactttgccacatggataca
attgactggagggacatcgtgagggttccagacgctgagatagtggtgaagaacaacggg
gggaactgtccaccctgtcacgaagtctgcaaggggcgatgctgggggcctggaccagaa
gactgccagatattgaccaagaccatctgtgcccctcagtgtaacggtcgctgcttcggg
cccaatcctaaccagtgctgccacgatgaatgtgcaggtggctgctctggaccccaggac
acagattgcttcgcctgccgacacttcaatgacagtggtgcctgtgtgcccaggtgtcca
gcgccccttgtgtacaacaagctaacgttccagcttgagcccaacccccatatcaagtat
cagtacggaggagtctgtgttgccagttgtccccataactttgtggtggatcagacattt
tgtgtcagggcttgtcctgctgacaagatggaagtagataagaatggactcaagatgtgt
gagccttgcagagggctgtgcccaaaagcctgtgaggggacgggctctggaagccgctac
cagaccgtggactctagcaatatcgatgggttcgtgaactgtaccaagatcctgggcaac
ctggacttcctcatcactggcctcaatggtgacccctggcacaagatccctgcactggac
ccggaaaagctcaatgttttcaggacagtccgggagattacaggctacctaaacatccag
tcctggccccctcacatgcacaacttcagtgttttttccaacctgacgaccatcgggggc
agaagcctctacaatcggggcttctccttgttgatcatgaagaacttgaatgtcacgtct
ctgggcttccggtccctgaaggaaattagtgctgggcgtgtctacataagtgccaatcag
caactttgttaccaccactctctgaactggaccagacttctgcgggggcccgcagaggag
agacttgacatcaagtacaaccggcctctgggagaatgcgtggcagagggcaaagtgtgt
gatccactgtgctcctctgggggatgctggggcccaggccctggtcagtgcttgtcttgt
cgaaactacagccgggaaggtgtctgtgtgactcactgcaacgttctgcaaggggaaccc
cgagagtttgttcatgaggctcattgcttctcctgccatccagaatgccagcccatggag
ggcaccagcacgtgcaatggctcgggctccgacgcttgtgctcgatgcgcccattttcgt
gatgggccccactgtgtgaacagctgcccccatggaatcctaggtgccaaaggtccaatc
tacaaatatccagatgctcagaatgagtgccggccctgccacgagaactgcacccaaggg
tgtaagggaccagaactacaagactgtttaggccaagcagaggtattaatgagcaaacca
cacctggtcatagcggtgacagtaggactgactgtgatcttcctgattctgggaggctct
tttctctattggcgtggacgcaggattcagaataaaagggctatgagacgctacttggag
cggggtgagagcatcgagcctctggacccaagcgagaaggcaaacaaagtcttggctaga
atcttcaaagagacagagctgaggaaacttaaggtgcttggctctggtgtctttggaact
gtacacaaggggatttggattcccgagggtgaatccatcaagattccagtctgcattaaa
gtcatcgaggacaagagtgggcggcagagttttcaggctgtgactgatcacatgctggcc
gtcggcagcctggaccatgcccacattgtacggctgctgggactgtgcccagggtcatct
ctgcagcttgtcactcagtacttgcctctgggctctctccttgatcatgtaagacagcac
cgtgagacactgggaccacagctgctgctcaactggggagtacaaattgccaagggtatg
tattacctcgaggaacacagcatggtgcatagggaccttgcgctccggaatgtgatgctt
aagtcaccgagtcaagtccaggtggcagattttggtgtggctgacttgctgccgccagat
gacaagcagttactacacagtgaggccaagactccaattaaatggatggcccttgagagt
atccactttgggaaatacacacaccagagtgatgtctggagttacggtgtaaccgtttgg
gagttgatgaccttcggggcagagccctacgcagggctacgactggctgaaataccagac
ctgctggagaagggagagcggttagcacagccccagatctgcaccattgacgtctacatg
gtcatggtcaagtgttggatgattgacgagaatattcgcccaacctttaaagaactggcc
aatgagtttaccaggatggcccgggacccaccaaggtatctggtcatcaagagagcgagt
gggcctggaatacctcctgcagcagagccatctgctctgagcaccaaagagttgcaggat
gcagagctggagccagacctggacctcgacctagacgtggaggtagaagaggagggcctg
gcgaccacactgggttctgccctcagcttgcctacaggaacgcttacccggccacgtggg
agccagagtcttttaagtccttcgtctggatacatgcccatgaaccagagcaaccttggg
gaggcttgtctggattctgcggttttggggggtcgcgaacagttctcccgtcccatctct
ctgcacccgatcccacgggggcgtcaaacgtcagagtcatcagagggccatgtgacgggc
tctgaggctgaactccaagagagagtatcaatgtgtaggagccggagccggagccggagc
ccacggccacgtggggacagtgcctaccattcgcagcgacacagcctgcttactcccgtc
accccgctctccccaccagggttagaggaagaggatggcaatggttatgtcatgccagat
acgcacctcagaggtacatcctcttcccgggaaggcaccctttcgtcagtaggtctcagt
tctgtgctgggtaccgaagaggaagatgaagatgaggagtatgaatacatgaaccggaag
aggaggggtagcccggctcggccccccagacctggttccctggaagagctgggctatgag
tacatggatgtgggttcagacctcagtgcttctctgggcagtacgcagagttgcccactc
catcccatggccatcgtgccctctgctggcacgactccagatgaggactatgaatacatg
aaccgcaggcgtggtgcgggcggttccggaggggattatgcagctatgggggcctgccca
gcagctgaacaagggtatgaggaaatgcgagctttccaggggcctggacatcaagccccc
catgttcgttatgcccgcctcaaaactctgcgtagtttagaagccactgactccgccttt
gacaaccccgattactggcatagcaggcttttccctaaggctaacgcccagagaatttga
DBGET
integrated database retrieval system
