KEGG   Mus musculus (mouse): 16449Help
Entry
16449             CDS       T01002                                 

Gene name
Jag1, ABE2, Gsfabe2, Htu, Ozz, Ser-1
Definition
(RefSeq) jagged 1
  KO
K06052  jagged-1
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01522  Endocrine resistance
mmu04330  Notch signaling pathway
mmu04371  Apelin signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu04668  TNF signaling pathway
mmu05165  Human papillomavirus infection
mmu05200  Pathways in cancer
mmu05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    16449 (Jag1)
   04371 Apelin signaling pathway
    16449 (Jag1)
   04668 TNF signaling pathway
    16449 (Jag1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    16449 (Jag1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    16449 (Jag1)
  09162 Cancer: specific types
   05224 Breast cancer
    16449 (Jag1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    16449 (Jag1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    16449 (Jag1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mmu04090]
    16449 (Jag1)
CD molecules [BR:mmu04090]
 Proteins
  16449 (Jag1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EGF hEGF MNNL EGF_2 DSL EGF_CA cEGF EGF_3 MAP17
Motif
Other DBs
NCBI-GeneID: 16449
NCBI-ProteinID: NP_038850
MGI: 1095416
Ensembl: ENSMUSG00000027276
Vega: OTTMUSG00000015560
UniProt: Q9QXX0 Q3UVN4
LinkDB All DBs
Position
2 F3; 2 67.73 cM
AA seq 1218 aa AA seqDB search
MRSPRTRGRPGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGGVRN
PGDRKCTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRI
VLPFSFAWPRSYTLLVEAWDSSNDTIQPDSIIEKASHSGMINPSRQWQTLKQNTGIAHFE
YQIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPDCNKAICRQGCSP
KHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCNEPWQCLCETNWGGQLCDKDLNYC
GTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSGFEC
ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP
CVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA
GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQC
YNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVIDSCTVAMASNDTPEGVRYISSNVCG
PHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCKNGGTCIDGVNSYKCICSDGWE
GAHCENNINDCSQNPCHYGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTC
YDEVDTFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGDSFTCVCKEGWEGPICT
QNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEIN
GYQCICPPGHSGAKCHEVSGRSCITMGRVILDGAKWDDDCNTCQCLNGRVACSKVWCGPR
PCRLHKSHNECPSGQSCIPVLDDQCFVRPCTGVGECRSSSLQPVKTKCTSDSYYQDNCAN
ITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIACEPSLSANNEIHVAISAED
IRDDGNPVKEITDKIIDLVSKRDGNSSLIAAVAEVRVQRRPLKNRTDFLVPLLSSVLTVA
WVCCLVTAFYWCVRKRRKPSSHTHSAPEDNTTNNVREQLNQIKNPIEKHGANTVPIKDYE
NKNSKMSKIRTHNSEVEEDDMDKHQQKVRFAKQPVYTLVDREEKAPSGTPTKHPNWTNKQ
DNRDLESAQSLNRMEYIV
NT seq 3657 nt NT seq  +upstreamnt  +downstreamnt
atgcggtccccacggacgcgcggccggcccgggcgccccctgagtcttctgctcgccctg
ctctgtgccctgcgagccaaggtgtgcggggcctcgggtcagtttgagctggagatcctg
tccatgcagaacgtgaatggagagctacagaatgggaactgttgtggtggagtccggaac
cctggcgaccgcaagtgcacccgcgacgagtgtgatacgtacttcaaagtgtgcctcaag
gagtatcagtcccgcgtcactgccgggggaccctgcagcttcggctcagggtctacgcct
gtcatcgggggtaacaccttcaatctcaaggccagccgtggcaacgaccgtaatcgcatc
gtactgcctttcagtttcgcctggccgaggtcctacactttgctggtggaggcctgggat
tccagtaatgacactattcaacctgatagcataattgaaaaggcttctcactcaggcatg
ataaaccctagccggcaatggcagacactgaaacaaaacacagggattgcccacttcgag
tatcagatccgagtgacctgtgatgaccactactatggctttggctgcaataagttctgt
cgtcccagagatgacttctttggacattatgcctgtgaccagaacggcaacaaaacttgc
atggaaggctggatgggtcctgattgcaacaaagctatctgccgacagggctgcagtccc
aagcatgggtcttgtaaacttccaggtgactgcaggtgccagtacggttggcagggcctg
tactgcgacaagtgcatcccgcacccaggatgtgtccacggcacctgcaatgaaccctgg
cagtgcctctgtgagaccaactggggtggacagctctgtgacaaagatctgaattactgt
gggactcatcagccctgtctcaaccggggaacatgtagcaacactgggcctgacaaatac
cagtgctcctgcccagagggctactcgggccccaactgtgaaattgctgagcatgcttgt
ctctctgacccctgccataaccgaggcagctgcaaggagacctcctcaggctttgagtgt
gagtgttctccaggctggactggccccacgtgttccacaaacatcgatgactgttctcca
aataactgttcccatgggggcacctgccaggatctggtgaatggattcaagtgtgtgtgc
ccgccccagtggactggcaagacttgtcagttagatgcaaatgagtgcgaggccaaacct
tgtgtaaatgccagatcctgtaagaatctgattgccagctactactgtgattgccttcct
ggctggatgggtcagaactgtgacataaatatcaatgactgccttggccagtgtcagaat
gacgcctcctgtcgggatttggttaatggttatcgctgtatctgtccacctggctatgca
ggcgatcactgtgagagagacatcgatgagtgtgctagcaacccctgcttgaatgggggt
cactgtcagaatgaaatcaacagattccagtgtctctgtcccactggtttctctggaaac
ctctgtcagctggacatcgattactgcgagcccaacccttgccagaatggcgcccagtgc
tacaatcgtgccagtgactatttctgcaagtgccccgaggactatgagggcaagaactgc
tcacacctgaaagaccactgccgtaccaccacctgcgaagtgattgacagctgcactgtg
gccatggcctccaacgacacgcctgaaggggtgcggtatatctcttctaacgtctgtggt
ccccatgggaagtgcaagagccagtcgggaggcaaattcacctgtgactgtaacaaaggc
ttcaccggcacctactgccatgaaaatatcaacgactgcgagagcaacccctgtaaaaac
ggtggcacctgcatcgatggcgttaactcctacaagtgtatctgtagtgacggctgggag
ggagcgcactgtgagaacaacataaatgactgtagccagaacccttgtcactacgggggt
acatgtcgagacctggtcaatgacttttactgtgactgcaaaaatggctggaaaggaaag
acttgccattcccgtgacagccagtgtgacgaagccacgtgtaataatggtggtacctgc
tatgatgaagtggacacgtttaagtgcatgtgtcccggtggctgggaaggaacaacctgt
aatatagctagaaacagtagctgcctgccgaacccctgtcataatggaggtacctgcgtg
gtcaatggagactccttcacctgtgtctgcaaagaaggctgggaggggcctatttgtact
caaaataccaacgactgcagtccccatccttgttacaatagcgggacctgtgtggacgga
gacaactggtatcggtgcgaatgtgccccgggttttgctgggccagactgcaggataaac
atcaatgagtgccagtcttccccttgtgcctttggggccacctgtgtggatgagatcaat
ggctaccagtgtatctgccctccaggacatagtggtgccaagtgccatgaagtttcaggg
cgatcttgcatcaccatggggagagtgatacttgatggggccaagtgggatgatgactgt
aacacctgccagtgcctgaatggacgggtggcctgctccaaggtctggtgtggcccgaga
ccttgcaggctccacaaaagccacaatgagtgccccagtgggcagagctgcatcccggtc
ctggatgaccagtgtttcgtgcgcccctgcactggtgttggcgagtgtcggtcctccagc
ctccagccagtgaagaccaagtgcacatctgactcctattaccaggataactgtgcaaac
atcactttcacctttaacaaagagatgatgtctccaggtcttaccaccgaacacatttgc
agcgaattgaggaatttgaatatcctgaagaatgtttctgctgaatattcgatctacata
gcctgtgagccttccctgtcagcaaacaatgaaatacacgtggccatctctgcagaagac
atccgggatgatgggaaccctgtcaaggaaattaccgataaaataatagatctcgttagt
aaacgggatggaaacagctcacttattgctgcggttgcagaagtcagagttcagaggcgt
cctctgaaaaacagaacagatttcctggttcctctgctgagctctgtcttaacagtggct
tgggtctgttgcttggtgacagccttctactggtgtgtaaggaagcggcggaagcccagc
agccacactcactccgcccccgaggacaacaccaccaacaatgtgcgggagcagctgaac
caaatcaaaaaccccatcgagaaacacggagccaacacggtccccattaaggattacgag
aacaaaaactcgaaaatgtcaaaaatcaggacacacaactcggaagtggaggaggatgac
atggataaacaccagcagaaagtccgctttgccaaacagccagtgtatacgctggtagac
agagaggagaaggcccccagcggcacgccgacaaaacacccgaactggacaaataaacag
gacaacagagacttggaaagtgcccagagcttgaaccggatggaatacatcgtatag

KEGG   Mus musculus (mouse): 16450Help
Entry
16450             CDS       T01002                                 

Gene name
Jag2, D12Ggc2e, Serh, mJagged2-1, sm
Definition
(RefSeq) jagged 2
  KO
K21635  jagged-2
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01522  Endocrine resistance
mmu04330  Notch signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu05200  Pathways in cancer
mmu05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    16450 (Jag2)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    16450 (Jag2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    16450 (Jag2)
  09162 Cancer: specific types
   05224 Breast cancer
    16450 (Jag2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    16450 (Jag2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EGF hEGF MNNL DSL EGF_2 EGF_CA NTP_transf_3 MFS_2
Motif
Other DBs
NCBI-GeneID: 16450
NCBI-ProteinID: NP_034718
MGI: 1098270
Ensembl: ENSMUSG00000002799
UniProt: Q9QYE5
LinkDB All DBs
Position
12 F1; 12 61.37 cM
AA seq 1247 aa AA seqDB search
MRARGWGRLPRRLLLLLVLCVQATRPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAG
GCGRDECDTYVRVCLKEYQAKVTPTGPCSYGYGATPVLGGNSFYLPPAGAAGDRARARSR
TGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPDEELLIERVSHAGMINPEDRWKS
LHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKEC
KEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCVEPWHCDCETNWG
GLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGG
SCHEVPSGFECHCPSGWNGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATC
QLDANECEGKPCLNAFSCKNLIGGYYCDCLPGWKGINCQININDCHGQCQHGGTCKDLVN
GYQCVCPRGFGGRHCELEYDKCASSPCRRGGICEDLVDGFRCHCPRGLSGLHCEVDMDLC
EPSPCLNGARCYNLEGDYYCACPEDFGGKNCSVPRDTCPGGACRVIDGCGFEAGSRARGV
APSGICGPHGHCVSLPGGNFSCICDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFRC
FCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYT
CSNGGTCYDSGDTFRCACPPGWKGSTCTIAKNSSCVPNPCVNGGTCVGSGDSFSCICRDG
WEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGA
TCVDEINGYRCSCPPGRSGPRCQEVVIFTRPCWSRGMSFPHGSSWMEDCNSCRCLDGHRD
CSKVWCGWKPCLLSGQPSDPSAQCPPGQQCQEKAVGQCLQPPCENWGECTAEEPLPPSTP
CQPRSSHLDNNCARLTLRFNRDQVPQGTTVGAICSGIRALPATRAAAHDRLLLLLCDRAS
SGASAVEVAVSFSPARDLPDSSLIQSTAHAIVAAITQRGNSSLLLAVTEVKVETVVMGGS
STGLLVPVLCSVFSVLWLACVVICVWWTRKRRKERERSRLPRDESANNQWAPLNPIRNPI
ERPGGSGLGTGGHKDILYQCKNFTPPPRRAGEALPGPAGHGAGGEDEEDEELSRGDGDSP
EAEKFISHKFTKDPSCSLGRPARWAPGPKVDNRAVRSTKDVRRAGRE
NT seq 3744 nt NT seq  +upstreamnt  +downstreamnt
atgcgggcacgcggctggggacgcctgcctcggcggctgctgctgctactggttctgtgc
gtgcaggcgacgcggcccatgggctatttcgagctgcagctgagcgcgctgcggaacgtg
aacggggagctgctgagcggcgcctgctgtgacggcgacggccggacgacgcgcgcgggg
ggctgcggccgcgacgagtgcgacacgtacgtgcgcgtgtgccttaaggagtaccaggcc
aaggtgacgcccacggggccctgcagctacggctacggcgccacgcccgtgctgggtggc
aactccttctacctgccgccggcgggcgctgcgggggaccgagcgcgcgcgcggtctcgg
accggcggccaccaggacccgggcctcgtcgtcattccctttcagttcgcctggccgcgt
tctttcaccctcatcgtggaggcctgggactgggacaatgacaccactccagatgaggag
ctgctgattgagcgggtgtcgcacgctggcatgatcaaccccgaggaccgctggaagagc
ctgcacttcagcggccacgtggcacacctggagctgcagatccgagtacgctgtgatgag
aactactacagtgccacctgcaacaagttctgccggccccgcaacgacttctttggccac
tatacctgcgaccagtacggcaacaaggcctgcatggatggctggatgggcaaagaatgc
aaagaagccgtgtgtaaacaaggatgtaatttgctccacgggggatgcactgtgcctggg
gagtgcaggtgcagctacggctggcagggcaagttctgtgacgagtgtgtcccctaccct
ggctgcgtgcatggcagctgtgtggagccctggcactgtgactgtgagaccaactggggt
ggcctgctctgtgacaaagacctgaactactgtggcagccaccacccctgtgtcaacggg
ggtacctgcatcaatgctgagcctgaccaatacctctgcgcctgcccagatggctacttg
ggcaagaactgcgagcgggctgagcacgcctgtgcctccaacccgtgtgccaatgggggc
tcttgccacgaagtgccatctggctttgaatgccactgtccgtcaggatggaacggaccc
acctgtgcgctcgacattgatgagtgtgcctctaacccatgtgcagcgggtggtacctgc
gtggatcaggtggacggcttcgagtgcatctgcccggagcagtgggtgggggctacttgc
cagctggacgccaatgagtgtgaagggaagccgtgccttaatgctttttcttgcaaaaac
ctgattggcggctattactgtgattgcctcccgggctggaagggcatcaactgccaaatc
aacatcaacgattgccatgggcagtgtcagcatgggggcacctgcaaggacctggtcaat
gggtaccagtgtgtgtgcccgcggggctttggaggtcgccattgcgaactagagtacgac
aagtgtgccagcagcccctgccgccggggtggcatctgtgaggacctggtggatggcttc
cgctgccactgcccacggggcctctctgggctgcactgtgaggtggacatggatctctgt
gaaccaagcccctgcctcaacggtgctcgctgctacaaccttgagggtgactactactgc
gcctgcccagaagactttggtggcaagaactgctcagtgcccagggacacatgccctggc
ggggcatgtagagtgatcgatggctgcgggttcgaggcagggtccagggcacgcggtgtc
gcaccctctggtatatgtggccctcacgggcactgcgttagcctgcctgggggaaacttc
tcctgcatctgtgacagcggcttcacaggcacctactgccatgaaaacattgacgactgc
atgggccagccctgccgcaacgggggcacgtgcattgacgaagtggactccttccgctgc
ttctgccccagtggctgggaaggagaactctgtgacatcaatcccaacgactgcctcccc
gacccctgccacagccgcggccgctgctatgacctggtcaatgacttctactgtgcctgt
gacgatggctggaagggcaagacctgccactcacgcgagttccagtgtgacgcctacacc
tgcagcaacggtggcacatgctatgacagcggcgacaccttccgctgcgcgtgccctccg
ggctggaagggcagcacctgcaccatcgccaagaacagcagctgtgtgcccaatccctgt
gtgaatggaggcacctgcgtgggcagcggagactctttctcctgcatctgccgggatggc
tgggagggccgcacctgcacacataacaccaatgactgcaaccctctgccctgctataac
ggaggcatctgtgttgatggcgtcaactggttccgctgcgagtgtgcgcctggctttgcg
ggtcctgactgccgtatcaacattgatgagtgccagtcctcgccctgtgcctacggagcc
acgtgtgtggatgagatcaacgggtaccgctgcagctgcccaccaggtcgttctggcccc
aggtgccaggaagtggtcatattcacgaggccctgctggtcccggggaatgtccttcccg
catgggagttcctggatggaagactgcaacagctgccgctgcctggatggccaccgggat
tgtagcaaggtatggtgcggatggaagccttgcctgctctctggtcagcccagcgatccg
agtgcccagtgccccccagggcagcaatgtcaggagaaggccgtgggtcagtgcttgcag
ccaccctgtgagaactggggggagtgtacagcggaggagcctctgccacccagcaccccc
tgtcagccacggagcagtcatttggacaacaactgtgcccgactcacactgcgcttcaac
cgtgatcaagtgcctcagggcaccaccgtgggcgctatctgctctggaatccgagccttg
cctgccacgagggcggcggcacacgaccgcctcctcctgctgctttgtgatcgagcatcc
tcgggggccagtgctgtggaggtggctgtgtctttcagccctgcaagggacctgcctgac
agcagcctgatccagagcacagcccacgccatcgtggctgctatcactcagagaggaaat
agctcactgctgctggctgtcaccgaggtcaaggtggaaacagttgttatgggtggctct
tccacaggtctgttggtgcccgtgctgtgcagcgtgttcagtgtgctgtggctcgcctgt
gtggttatctgcgtatggtggacacgaaagcgcaggaaagaacgtgagaggagccggcta
ccacgggatgagagcgccaacaaccagtgggccccgctcaatcccatccgcaaccccatt
gagcggccaggcggcagcggtctgggaactgggggccacaaggacatactctaccagtgc
aaaaacttcacaccgccgccccgcagggcaggcgaggcactgcccgggccagctggccat
ggggctggtggggaggacgaggaggatgaagagctgagccgtggagatggggactcccca
gaggcagagaagttcatctcacacaagttcaccaaagaccccagctgctccctcggaagg
ccagcccgctgggctccagggcccaaagtggacaaccgcgccgtcagaagtaccaaggac
gtgcgccgtgctggcagggaatag

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