KEGG   Mus musculus (mouse): 17977Help
Entry
17977             CDS       T01002                                 

Gene name
Ncoa1, KAT13A, NCoA-1, NRC-1, SRC-1, SRC-a, SRC1, bHLHe74, mNRC-1
Definition
(RefSeq) nuclear receptor coactivator 1
  KO
K09101  nuclear receptor coactivator 1 [EC:2.3.1.48]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04915  Estrogen signaling pathway
mmu04919  Thyroid hormone signaling pathway
mmu05200  Pathways in cancer
mmu05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    17977 (Ncoa1)
   04919 Thyroid hormone signaling pathway
    17977 (Ncoa1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    17977 (Ncoa1)
  09162 Cancer: specific types
   05224 Breast cancer
    17977 (Ncoa1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    17977 (Ncoa1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     17977 (Ncoa1)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    17977 (Ncoa1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PAS_11 NCOA_u2 DUF1518 SRC-1 Nuc_rec_co-act PAS PAS_3 DUF4927 PAS_9 HLH PAS_4 PAS_12
Motif
Other DBs
NCBI-GeneID: 17977
NCBI-ProteinID: NP_035011
MGI: 1276523
Ensembl: ENSMUSG00000020647
UniProt: P70365
LinkDB All DBs
Structure
PDB: 

Position
12; 12 A1.1
AA seq 1405 aa AA seqDB search
MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL
SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL
DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG
VPWPQEATRRNSHTFNCRMLIHPPEDPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ
SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF
QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG
IHIIDREHSGLSPQDDSNSGMSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARVNR
QQSSDLNSSSSHTNSSNNQGNFGCSPGNQIVANVALNQGQAGSQSSNPSLNLNNSPMEGT
GIALSQFMSPRRQANSGLATRARMSNNSFPPNIPTLSSPVGITSGACNNNNRSYSNIPVT
SLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDSKEIASILNEMIQSD
NSDNSANEGKPLDSGLLHNNDRLSEGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKD
VLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSVP
ASTAVSVSGQSQGSASIKLELDAAKKKESKDHQLLRYLLDKDEKDLRSTPNLCLDDVKVK
VEKKEQMDPCNTNPTPMTKPAPEEVKLESQSQFTADLDQFDQLLPTLEKAAQLPSLCETD
RMDGAVTGVSIKAEVLPASLQPTTARAAPRLSRLPELELEAIDNQFGQPGAGDQIPWANN
TLTTINQNKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRA
LGIDKLVQGGGLDVLSERFPPQQATPPLMMEDRPTLYSQPYSSPSPTAGLSGPFQGMVRQ
KPSLGAMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQ
AILNQFAANAPVGMNMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQIIQQQRAML
MRHQSFGNNIPPSSGLPVQMGTPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANP
EASLATRSSMVNRGMAGNMGGQFGAGISPQMQQNVFQYPGPGLVPQGEATFAPSLSPGSS
MVPMPVPPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQSQPAPAQPGVYNN
MSITVSMAGGNANIQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSST
DLLKTDADGNQDKKTEEFFSVVTTD
NT seq 4218 nt NT seq  +upstreamnt  +downstreamnt
atgagtggccttggggacagttcatcagaccctgcaaacccagactctcataagagaaaa
ggatcgccatgtgacacgctggcatcaagtactgagaagaggcgcagggagcaagaaaat
aagtatttagaagaactagctgaactactgtctgccaacatcagtgacattgacagcttg
agtgtaaaaccagataaatgcaagattttgaagaagacagtagatcagatacagctaatg
aagagaatggagcaagagaaatccacgactgatgatgacgtgcagaagtccgacatctcc
tcgagcagccaaggagtgatagagaaggagtcgctgggccctcttcttctggaggctttg
gatggatttttctttgttgtgaactgtgaaggaagaattgtatttgtatcagaaaatgtg
accagctacttgggttacaatcaggaagaattaatgaataccagcgtctacagcatactg
catgtgggagatcatgcagaatttgtcaagaatctgctaccaaaatcactagtaaatgga
gttccttggcctcaagaggcaacacgccgaaatagccatacatttaactgcaggatgcta
attcaccctccagaggacccaggtactgagaaccaagaagcttgccagcgctatgaagta
atgcagtgtttcacagtgtcacagccaaaatccatccaagaagatggtgaagatttccag
tcatgtctgatttgtattgctcgacgattacctcggcctccagccattacaggtgtagaa
tcctttatgaccaagcaagatactacaggcaaaatcatctctattgacactagctccctg
agggctgctggcaggactggctgggaagacctagtaaggaagtgcatctatgctttcttc
caacctcagggcagagagccatcttacgcccggcagctgtttcaagaagtgatgactcgt
ggcactgcctccagcccatcctatagattcatattgaatgatgggacaatgcttagcgcc
cacaccaagtgtaaactttgctaccctcaaagtcctgacatgcagcctttcatcatggga
attcatatcatcgacagggagcacagtgggctttctcctcaagatgacagtaattctgga
atgtcaattccccgaataaatccctcagtcaatcctggtatctctccagcccatggtgtg
acccgttcatccacgttgccaccatccaacaacaacatggtctctgccagagtaaaccgc
caacagagctcagacctcaacagcagcagcagtcatactaactctagcaacaaccaaggg
aactttggatgttcacctggaaatcagattgtagccaatgttgccttaaaccagggacag
gcaggttcccagagcagcaatccctctttaaacctcaataattctcctatggaaggtaca
ggaattgccctctcacagttcatgtctccgaggagacaagctaattctggcttggcaaca
agggccaggatgtcaaacaattcatttcctccaaatattccaacattaagctccccagtt
ggcattactagtggtgcctgtaataataataatcgatcctattcaaatatcccagtaaca
tctttacaaggtatgaatgaaggacccaataactctgttggcttctctgctgggtctcca
gtccttcggcagatgagctcacagaattcacctagcagattaagtatgcaaccagcaaag
gctgagtccaaagacagcaaagagattgcatccattttaaatgaaatgattcagtccgac
aacagcgacaacagtgctaacgaaggcaagcctctggactcaggacttctgcataacaat
gacagactctcagaaggagacagtaaatactctcaaactagtcacaagctagtacagcta
ttgactacgaccgcagagcagcagttacggcatgccgacatagacacaagctgcaaagat
gtactgtcttgcactggtacttccagctctgcctcctctaacccctcaggaggtacttgt
ccctcttctcacagctctctgactgagcggcataaaattctgcaccggcttttacaggag
ggcagcccctcagacatcaccactttgtctgtggaacccgagaagaaggacagtgtgcca
gcctctactgctgtgtcagtgtctggacaatcccaggggagtgccagcataaaactggaa
ctggatgctgcaaagaaaaaagagtcaaaagaccatcagctcctacgctaccttttagac
aaagatgagaaagatttaaggtccactccaaacctgtgcctggatgacgtaaaggtcaaa
gtggagaagaaagaacagatggatccttgtaacacaaacccaaccccaatgaccaaacct
gctcctgaggaagttaaactggagtcccagagccagtttacagctgaccttgaccagttt
gatcagttattgcccaccctggagaaggcagcacagttgccgagcttgtgcgagacagac
aggatggatggtgcggtcaccggtgtcagcatcaaggcggaggtcctgccagcgtcactc
cagcccaccactgccagagctgcccccaggctgagcagattgcctgaactagaattagaa
gcgatcgataaccagtttggacaaccaggagcgggggatcagattccatgggcaaataat
actttgacaacaataaatcagaataaaccagaagaccaatgtattagctcacagctggat
gagctcctctgtccaccaacaacagtagaaggaagaaacgatgagaaggcccttctggaa
caactggtgtctttcctcagtggcaaagatgaaacggagctggctgagctagaccgggca
ctggggatcgacaagctcgtccagggaggcggattagatgtattatctgagcgatttcca
ccacagcaagcaacaccacctttgatgatggaagacagacccaccctctattcccagcca
tactcatctccttctcccaccgctggtctctctggccctttccaaggcatggtccggcag
aagccttcactgggggctatgccggttcaagtaacacctcctcgaggaaccttttcaccc
aacatgggcatgcagccccggcagactctcaatagacctccagctgcacccaaccagctt
cggctgcagctgcagcagcggctacaggggcagcagcagttgatgcaccaaaaccggcaa
gccatcttgaaccagtttgcagcaaatgctcctgttggcatgaacatgaggtcaggcatg
cagcagcagatcacacctcagccacccttgaatgctcagatgttggcccagcgccagcgg
gagttgtacagtcagcagcatcgacagaggcaaattatacagcagcagagagccatgctc
atgaggcaccaaagttttgggaacaacatccctccttcatctggactcccagttcaaatg
gggactccccgtcttcctcagggtgctccccagcagttcccctacccaccaaactatggt
acaaacccaggaaccccacctgcctccaccagccctttctctcaactggcagcaaaccct
gaggcctccttggccacccgcagcagcatggtgaacagaggcatggcagggaacatggga
ggacagtttggcgctggcatcagtcctcagatgcagcagaatgtcttccaatatccagga
ccaggactagttccccaaggtgaggccacctttgccccatctctaagccctgggagctcc
atggtgccgatgccagtccctcctcctcaaagctctctgctccagcaaactccacctact
tctgggtaccagtcaccagacatgaaggcctggcagcaaggaacaatgggaaacaacaat
gtgttcagtcaagctgtccagagccagcctgcacctgcacagccaggagtgtacaacaac
atgagcatcaccgtgtccatggcaggtggaaacgcaaacattcagaacatgaatccaatg
atgggccagatgcaaatgagctctctgcagatgccagggatgaatactgtgtgctctgag
cagatgaatgatccagcactgagacacacaggcctctactgcaaccagctctcgtccact
gaccttctcaaaacagacgcagatggaaaccaggacaagaagacagaagagttcttctct
gtggtgactacagactag

KEGG   Mus musculus (mouse): 17979Help
Entry
17979             CDS       T01002                                 

Gene name
Ncoa3, 2010305B15Rik, AW321064, Actr, Aib1, KAT13B, Rac3, Src3, Tram-1, Tram1, bHLHe42, p/Cip, pCip
Definition
(RefSeq) nuclear receptor coactivator 3
  KO
K11256  nuclear receptor coactivator 3 [EC:2.3.1.48]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01522  Endocrine resistance
mmu04915  Estrogen signaling pathway
mmu04919  Thyroid hormone signaling pathway
mmu05200  Pathways in cancer
mmu05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    17979 (Ncoa3)
   04919 Thyroid hormone signaling pathway
    17979 (Ncoa3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    17979 (Ncoa3)
  09162 Cancer: specific types
   05224 Breast cancer
    17979 (Ncoa3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    17979 (Ncoa3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    17979 (Ncoa3)
Enzymes [BR:mmu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     17979 (Ncoa3)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    17979 (Ncoa3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: NCOA_u2 PAS_11 SRC-1 DUF4927 Nuc_rec_co-act DUF1518 PAS PAS_3 PAS_9 HLH PAS_4 PAS_2 Pet20
Motif
Other DBs
NCBI-GeneID: 17979
NCBI-ProteinID: NP_032705
MGI: 1276535
Ensembl: ENSMUSG00000027678
Vega: OTTMUSG00000001163
UniProt: Q05BA5 A5D6Q2
LinkDB All DBs
Position
2; 2 H3
AA seq 1403 aa AA seqDB search
MSGLGESSLDPLAAESRKRKLPCDAPGQGLVYSGEKWRREQESKYIEELAELISANLSDI
DNFNVKPDKCAILKETVRQIRQIKEQGKTISSDDDVQKADVSSTGQGVIDKDSLGPLLLQ
ALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYSILHEQDRKDFLKHLPKSTVN
GVSWTNENQRQKSHTFNCRMLMKTHDILEDVNASPETRQRYETMQCFALSQPRAMLEEGE
DLQCCMICVARRVTAPFPSSPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQR
FFSLNDGQSWSQKRHYQEAYVHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGF
ISTHFLQREQNGYRPNPNPAGQGIRPPAAGCGVSMSPNQNVQMMGSRTYGVPDPSNTGQM
GGARYGASSSVASLTPGQSLQSPSSYQNSSYGLSMSSPPHGSPGLGPNQQNIMISPRNRG
SPKMASHQFSPAAGAHSPMGPSGNTGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKL
DNSPNMNISQPSKVSGQDSKSPLGLYCEQNPVESSVCQSNSRDHPSEKESKESSGEVSET
PRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDPNCKDSSVSVTSPSGVSSSTSGTVS
STSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTASCGEGTTRQEQLSP
KKKENNALLRYLLDRDDPSDVLAKELQPQADSGDSKLSQCSCSTNPSSGQEKDPKIKTET
NEEVSGDLDNLDAILGDLTSSDFYNNPTNGGHPGAKQQMFAGPSSLGLRSPQPVQSVRPP
YNRAVSLDSPVSVGSGPPVKNVSAFPGLPKQPILAGNPRMMDSQENYGANMGPNRNVPVN
PTSSPGDWGLANSRASRMEPLASSPLGRTGADYSATLPRPAMGGSVPTLPLRSNRLPGAR
PSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQMLQMRTGEIPMGMGVNPYSPAVPSNQPGS
WPEGMLSMEQGPHGSQNRPLLRNSLDDLLGPPSNAEGQSDERALLDQLHTLLSNTDATGL
EEIDRALGIPELVNQGQALESKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPLQGGFNLQ
GQSPSFNSMMGQISQQGSFPLQGMHPRAGLVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQ
ALEMKMENPAGTAVMRPMMPQQAFFNAQMAAQQKRELMSHHLQQQRMAMMMSQPQPQAFS
PPPNVTASPSMDGVLAGSAMPQAPPQQFPYPANYGMGQPPEPAFGRGSSPPSAMMSSRMG
PSQNAMVQHPQPTPMYQPSDMKGWPSGNLARNGSFPQQQFAPQGNPAAYNMVHMNSSGGH
LGQMAMTPMPMSGMPMGPDQKYC
NT seq 4212 nt NT seq  +upstreamnt  +downstreamnt
atgagtggactaggcgaaagctctttggatccgctggccgctgagtctcggaaacgcaaa
ctgccctgtgatgccccaggacaggggcttgtctacagtggtgagaagtggcgacgggag
caggagagcaagtacatagaggagctggcagagctcatctctgcaaatctcagcgacatc
gacaacttcaatgtcaagccagataaatgtgccatcctaaaggagacagtgagacagata
cggcaaataaaagaacaaggaaaaactatttccagtgatgatgatgttcaaaaagctgat
gtgtcttctacagggcagggagtcattgataaagactctttaggaccgcttttactacag
gcactggatggtttcctgtttgtggtgaatcgagatggaaacattgtattcgtgtcagaa
aatgtcacacagtatctgcagtacaagcaggaggacctggttaacacaagtgtctacagc
atcttacatgagcaagaccggaaggattttcttaaacacttaccaaaatccacagttaat
ggagtttcttggactaatgagaaccagagacaaaaaagccatacatttaattgtcgtatg
ttgatgaaaacacacgacattttggaagacgtgaatgccagtcccgaaacacgccagaga
tatgaaacaatgcagtgctttgccctgtctcagcctcgcgctatgctggaagaaggagaa
gacttgcagtgctgtatgatctgcgtggctcgccgcgtgactgcgccattcccatccagt
cctgagagctttattaccagacatgacctttccggaaaggttgtcaatatagatacaaac
tcacttagatcttccatgaggcctggctttgaagacataatccgaagatgtatccagagg
ttcttcagtctgaatgatgggcagtcatggtcccagaagcgtcactatcaagaagcttat
gttcatggccacgcagagacccccgtgtatcgtttctccttggctgatggaactattgtg
agtgcgcagacaaaaagcaaactcttccgcaatcctgtaacgaatgatcgtcacggcttc
atctcgacccactttcttcagagagaacagaatggatacagaccaaacccaaatcccgca
ggacaaggcatccgacctcctgcagcagggtgtggcgtgagcatgtctccaaatcagaat
gtacagatgatgggcagccggacctatggcgtgccagaccccagcaacacagggcagatg
ggtggagctaggtacggggcttctagtagcgtagcctcactgacgccaggacaaagccta
cagtcgccatcttcctatcagaacagcagctatgggctcagcatgagcagtcccccccac
ggcagtcctggtcttggtcccaaccagcagaacatcatgatttcccctcggaatcgtggc
agcccaaagatggcctcccaccagttctctcctgctgcaggtgcacactcacccatggga
ccttctggcaacacagggagccacagcttttctagcagctccctcagtgccttgcaagcc
atcagtgaaggcgtggggacctctcttttatctactctgtcctcaccaggccccaaactg
gataattctcccaatatgaatataagccagccaagtaaagtgagtggtcaggactctaag
agccccctaggcttatactgtgaacagaatccagtggagagttcagtgtgtcagtcaaac
agcagagatcacccaagtgaaaaagaaagcaaggagagcagtggggaggtgtcagagacg
cccaggggacctctggaaagcaaaggccacaagaaactgctgcagttactcacgtgctcc
tccgacgaccgaggccattcctccttgaccaactctcccctggatccaaactgcaaagac
tcttccgttagtgtcaccagcccctctggagtgtcctcctcaacatcagggacagtgtct
tccacctccaatgtgcatgggtctctgttgcaagagaaacaccggattttgcacaagttg
ctgcagaatggcaactccccagcggaggtcgccaagatcactgcagaggccactgggaag
gacacgagcagcactgcttcctgtggagaggggacaaccaggcaggagcagctgagtcct
aagaagaaggagaataatgctctgcttagatacctgctggacagggatgaccccagtgat
gtgcttgccaaagagctgcagccccaggccgacagtggggacagtaaactgagtcagtgc
agctgctccaccaatcccagctctggccaagagaaagaccccaaaattaagaccgagacg
aacgaggaggtatcgggagacctggataatctagatgccattcttggagatttgaccagt
tctgacttctacaacaatcctacaaatggcggtcacccaggggccaaacagcagatgttt
gcaggaccgagttctctgggtttgcgaagtccacagcctgtgcagtctgttcgtcctcca
tataaccgagcggtgtctctggatagccctgtgtctgttggctcaggtccgccagtgaag
aatgtcagtgctttccctgggttaccaaaacagcccatactggctgggaatccaagaatg
atggatagtcaggagaattacggtgccaacatgggcccaaacagaaatgttcctgtgaat
ccgacttcctcccccggagactggggcttagctaactcaagggccagcagaatggagcct
ctggcatcaagtcccctgggaagaactggagccgattacagtgccactttacccagacct
gccatggggggctctgtgcctaccttgccacttcgttctaatcgactgccaggtgcaaga
ccatcgttgcagcaacagcagcagcaacagcagcaacagcaacaacaacagcagcaacag
cagcagcaacagcagcagcagcaacagcagcagatgcttcaaatgagaactggtgagatt
cccatgggaatgggagtcaatccctatagcccagcagtgccgtctaaccaaccaggttcc
tggccagagggcatgctctctatggaacaaggtcctcacgggtctcaaaataggcctctt
cttagaaactctctggatgatctgcttgggccaccttctaacgcagagggccagagtgac
gagagagctctgctggaccagctgcacacactcctgagcaacacagatgccacaggtctg
gaggagatcgacagggccttgggaattcctgagctcgtgaatcagggacaagctttggag
tccaaacaggatgttttccaaggccaagaagcagcagtaatgatggatcagaaggctgca
ctatatggacagacatacccagctcagggtcctccccttcaaggaggctttaaccttcag
ggacagtcaccatcgtttaactctatgatgggtcagattagccagcaaggcagctttcct
ctgcaaggcatgcatcctagagccggcctcgtgagaccaaggaccaacaccccgaagcag
ctgagaatgcagcttcagcagaggctacagggccagcagtttttaaatcagagccggcag
gcacttgaaatgaaaatggagaaccctgctggcactgctgtgatgaggcccatgatgccc
cagcaggctttctttaatgcccaaatggctgcccagcagaaacgagagctgatgagccat
cacctgcagcagcagaggatggcgatgatgatgtcacaaccacagcctcaggccttcagc
ccacctcccaacgtcaccgcctcccccagcatggacggggttttggcaggttcagcaatg
ccgcaagcccctccacaacagtttccatatccagcaaattacggaatgggacaaccacca
gagccagcctttggtcgaggctcgagtcctcccagtgcaatgatgtcatcaagaatgggg
ccttcccagaatgccatggtgcagcatcctcagcccacacccatgtatcagccttcagat
atgaaggggtggccgtcagggaacctggccaggaatggctccttcccccagcagcagttt
gctccccaggggaaccctgcagcctacaacatggtgcatatgaacagcagcggtgggcac
ttgggacagatggccatgacccccatgcccatgtctggcatgcccatgggccccgatcag
aaatactgctga

DBGET integrated database retrieval system