Mus musculus (mouse): 18669
Help
Entry
18669 CDS
T01002
Gene name
Abcb1b, Abcb, Abcb1, Mdr1, Mdr1b, Pgy, Pgy-, Pgy-1, Pgy1, md, mdr
Definition
(RefSeq) ATP-binding cassette, sub-family B (MDR/TAP), member 1B
KO
K05658
ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:
7.6.2.2
]
Organism
mmu
Mus musculus (mouse)
Pathway
mmu02010
ABC transporters
mmu04976
Bile secretion
mmu05206
MicroRNAs in cancer
mmu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
18669 (Abcb1b)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
18669 (Abcb1b)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
18669 (Abcb1b)
09162 Cancer: specific types
05226 Gastric cancer
18669 (Abcb1b)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
mmu02000
]
18669 (Abcb1b)
04147 Exosome [BR:
mmu04147
]
18669 (Abcb1b)
04090 CD molecules [BR:
mmu04090
]
18669 (Abcb1b)
Enzymes [BR:
mmu01000
]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.2 ABC-type xenobiotic transporter
18669 (Abcb1b)
Transporters [BR:
mmu02000
]
ABC transporters, eukaryotic type
ABCB (MDR/TAP) subfamily
ABCB1, 4, 5 subgroups
18669 (Abcb1b)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
18669 (Abcb1b)
CD molecules [BR:
mmu04090
]
Proteins
18669 (Abcb1b)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ABC_membrane
ABC_tran
SMC_N
AAA_16
ABC_ATPase
AAA_22
Rad17
Zeta_toxin
G-alpha
RsgA_GTPase
AAA
AAA_5
AAA_29
AAA_7
APS_kinase
AAA_14
AAA_30
PRK
DUF815
AAA_15
NTPase_1
Motif
Other DBs
NCBI-GeneID:
18669
NCBI-ProteinID:
NP_035205
MGI:
97568
Ensembl:
ENSMUSG00000028970
Vega:
OTTMUSG00000054347
UniProt:
P06795
B2RUR3
LinkDB
All DBs
Position
5 A1; 5 3.43 cM
AA seq
1276 aa
AA seq
DB search
MEFEENLKGRADKNFSKMGKKSKKEKKEKKPAVGVFGMFRYADWLDKLCMILGTLAAIIH
GTLLPLLMLVFGNMTDSFTKAEASILPSITNQSGPNSTLIISNSSLEEEMAIYAYYYTGI
GAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSK
INDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTLVILAVSPLIGLSSALWAKVLTSFTN
KELQAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLEEAKNVGIKKAITASISIGI
AYLLVYASYALAFWYGTSLVLSNEYSIGEVLTVFFSILLGTFSIGHLAPNIEAFANARGA
AFEIFKIIDNEPSIDSFSTKGYKPDSIMGNLEFKNVHFNYPSRSEVQILKGLNLKVKSGQ
TVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFA
TTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAI
ARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGF
DGGVIVEQGNHDELMREKGIYFKLVMTQTRGNEIEPGNNAYGSQSDTDASELTSEESKSP
LIRRSIYRSVHRKQDQERRLSMKEAVDEDVPLVSFWRILNLNLSEWPYLLVGVLCAVING
CIQPVFAIVFSRIVGVFSRDDDHETKRQNCNLFSLFFLVMGLISFVTYFFQGFTFGKAGE
ILTKRVRYMVFKSMLRQDISWFDDHKNSTGSLTTRLASDASSVKGAMGARLAVVTQNVAN
LGTGVILSLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKQLEISGKIATEAIE
NFRTIVSLTREQKFETMYAQSLQVPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAY
LVAQQLMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIRIIEKTPEIDSYS
TEGLKPTLLEGNVKFNGVQFNYPTRPNIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQL
LERFYDPMAGSVFLDGKEIKQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRAVSH
EEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEA
TSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLA
QKGIYFSMVQAGAKRS
NT seq
3831 nt
NT seq
+upstream
nt +downstream
nt
atggagtttgaagagaaccttaagggaagagcagacaagaacttctcgaagatgggcaaa
aagagtaaaaaggagaagaaagaaaagaaacctgctgttggcgtatttgggatgtttcgc
tatgcagattggctggacaagctgtgcatgattctgggaactctcgctgctattatccat
ggaacattacttcccctcttgatgctggtgtttggaaacatgacagatagttttacaaaa
gcagaagccagtattctgccaagcattactaatcaaagtggacccaacagtactctgatc
atcagcaacagcagtctggaggaagagatggccatatacgcctactattacaccgggatt
ggtgctggtgtgctcatagttgcctacatccaggtttcactttggtgcctggcagctgga
agacagatacacaagattaggcagaagtttttccatgctataatgaatcaggagataggc
tggtttgatgtgcatgatgttggggagctcaacacccggctcacagatgatgtctccaaa
attaatgacggaattggtgacaaaattgggatgttttttcagtccataaccacattttta
gccggttttatcataggatttataagtggttggaagctaacccttgtcattttggctgtc
agccctcttattggattgtcatctgctttgtgggcaaaggtattgacttcatttactaat
aaggaactccaggcttatgcaaaagctggagcagttgctgaagaagtcttagcagccatc
agaactgtgattgcctttggaggacaacagaaggaacttgaaaggtacaataaaaattta
gaagaagctaaaaatgttggcataaagaaagctatcacagccagcatttcgataggcatt
gcctacctgttggtctatgcatcatatgcactggcattctggtatgggacatccttggtc
ctctcaaatgaatattctattggagaagtgcttactgtcttcttctctattttgttgggg
acttttagtattggacacttggccccaaacatagaagcctttgcaaacgcacgaggggca
gcctttgaaatcttcaagataattgataacgagccaagcattgacagcttctcaacaaag
ggctacaaaccagacagtataatgggaaacttagagtttaaaaatgttcacttcaactac
ccatcgagaagcgaagttcagatcttgaagggcctcaatctgaaggtgaagagcggacag
acggtggccctggttggcaacagtggctgtggaaaaagcacaactgtccagctgatgcag
aggctctacgaccccctggagggcgtggtcagtatcgacggacaagacatcagaaccatc
aatgtgaggtatctgagggagatcattggtgtggtgagtcaggaacctgtgctgtttgcc
accacgatcgccgagaacattcgctatggccgagaagatgtcaccatggatgagattgag
aaagctgtcaaggaagccaatgcctatgacttcatcatgaaactgccccaccaatttgac
accctggttggtgagagaggggcgcagctgagtgggggacagaaacagagaatcgccatt
gcccgggccctggtccgcaatcccaagatccttttgttggacgaggccacctcagccctg
gatacagaaagtgaagctgtggtgcaggccgcactggataaggctagagaaggccggacc
accattgtgatagctcatcgcttgtctacagttcgtaatgctgacgtcattgctggtttt
gatggtggtgtcattgtggagcaaggaaatcatgatgagctcatgagagaaaagggcatt
tacttcaaacttgtcatgacacagactagaggaaatgaaattgaaccaggaaataatgct
tatggatcccagagtgacactgatgcttctgaactgacttcagaagaatccaaatcacct
ttaataaggagatcaatttacagaagtgtccacagaaagcaagaccaagagagaagactt
agtatgaaagaggctgtggatgaagatgtgcctctggtttccttttggcggatcctaaat
ctaaatctaagtgaatggccttatttacttgttggcgtactttgcgctgttataaatggg
tgcatacaaccagtgtttgccatagtattttcaaggattgtaggggttttttcaagagat
gatgaccatgaaactaaacgacagaattgtaatttgttttccctgttctttctggttatg
gggctgatttcttttgttacatatttctttcagggcttcacatttggcaaagccggagag
atcctcaccaagcgagtccgatacatggttttcaaatccatgctgagacaggatataagc
tggttcgatgaccataagaacagcactggctcactgaccaccaggctcgccagtgatgct
tctagtgttaaaggggcgatgggcgccaggcttgctgtagttacccagaatgtagcaaac
ctcgggacaggagtcatcctctccttagtctatggctggcagctgacacttctacttgta
gtaattataccgctcattgtattgggcggaattattgaaatgaagctgttgtctggccaa
gccttgaaggacaagaaacagcttgagatctctgggaagattgctacagaagcaattgaa
aacttccgcactattgtctctttgactcgggagcagaagtttgaaaccatgtatgcccag
agcttgcaggtaccatacagaaatgcgatgaagaaagcacacgtgtttgggatcacgttc
tccttcacccaggccatgatgtatttttcttatgctgcttgtttccggttcggtgcctac
ttggtggcacaacaactcatgacttttgaaaatgttatgttggtattttctgctgttgtc
tttggtgccatggcagctgggaatactagttcatttgctcctgactatgcgaaagccaaa
gtatcagcatctcatatcatcaggatcattgagaaaacccctgagattgacagctacagc
acagagggcttgaagcctactctgttagaaggaaatgtaaaatttaatggagtccagttt
aactatcccacccgacccaacatcccagtgcttcaggggctgagcctcgaggtgaagaag
ggccagacgttggccctggtgggcagcagtggctgtgggaagagcacagtggtccagctg
ctcgagcgcttctacgaccccatggctggatcagtgtttctagatggcaaagaaataaag
caactgaatgtccagtggctccgagctcaccttggcattgtgtcccaggagcccattctc
tttgactgcagcattgcagagaacatcgcctatggagacaacagccgggccgtgtctcat
gaggagattgtgagggcagccaaggaggccaacatccaccagttcatcgactcactgcct
gataaatacaacaccagagtaggagacaaaggcactcagctgtcgggtgggcagaagcag
cgcatcgccatcgcacgtgccctcgtcagacagcctcacattttacttctggacgaagca
acatcagctctggatacagaaagtgaaaaggttgtccaggaagcgctggacaaagccagg
gaaggccgcacctgcattgtgatcgctcaccgcctgtccaccatccagaacgcggacttg
atcgtggtgattgagaacggcaaagtcaaggagcacggcacccaccagcagctgctggcg
cagaagggcatctacttctcaatggtccaggctggagcaaagcgctcatga
Mus musculus (mouse): 18671
Help
Entry
18671 CDS
T01002
Gene name
Abcb1a, Abcb4, Evi, Evi32, Mdr, Mdr1a, Mdr3, P, P-, P-gp, Pgp, Pgy, Pgy-, Pgy-3, Pgy3, mdr-, mdr-3
Definition
(RefSeq) ATP-binding cassette, sub-family B (MDR/TAP), member 1A
KO
K05658
ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:
7.6.2.2
]
Organism
mmu
Mus musculus (mouse)
Pathway
mmu02010
ABC transporters
mmu04976
Bile secretion
mmu05206
MicroRNAs in cancer
mmu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
18671 (Abcb1a)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
18671 (Abcb1a)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
18671 (Abcb1a)
09162 Cancer: specific types
05226 Gastric cancer
18671 (Abcb1a)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
mmu02000
]
18671 (Abcb1a)
04147 Exosome [BR:
mmu04147
]
18671 (Abcb1a)
04090 CD molecules [BR:
mmu04090
]
18671 (Abcb1a)
Enzymes [BR:
mmu01000
]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.2 ABC-type xenobiotic transporter
18671 (Abcb1a)
Transporters [BR:
mmu02000
]
ABC transporters, eukaryotic type
ABCB (MDR/TAP) subfamily
ABCB1, 4, 5 subgroups
18671 (Abcb1a)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
18671 (Abcb1a)
CD molecules [BR:
mmu04090
]
Proteins
18671 (Abcb1a)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ABC_membrane
ABC_tran
SMC_N
AAA_16
ABC_ATPase
AAA_22
Rad17
Zeta_toxin
RsgA_GTPase
G-alpha
AAA
AAA_5
AAA_29
AAA_7
AAA_30
APS_kinase
AAA_14
DUF815
PRK
AAA_15
NTPase_1
DUF2057
DUF2207
Motif
Other DBs
NCBI-GeneID:
18671
NCBI-ProteinID:
NP_035206
MGI:
97570
Ensembl:
ENSMUSG00000040584
Vega:
OTTMUSG00000029053
UniProt:
P21447
LinkDB
All DBs
Structure
PDB:
5KO2
5KPD
4Q9H
5KPJ
4XWK
4Q9J
4Q9I
4Q9K
4Q9L
4M1M
4LSG
4KSB
3G5U
5KOY
4KSC
5KPI
4KSD
4M2T
3G61
4M2S
3G60
6Q81
6GDI
Thumbnails
Position
5 A1; 5 3.43 cM
AA seq
1276 aa
AA seq
DB search
MELEEDLKGRADKNFSKMGKKSKKEKKEKKPAVSVLTMFRYAGWLDRLYMLVGTLAAIIH
GVALPLMMLIFGDMTDSFASVGNVSKNSTNMSEADKRAMFAKLEEEMTTYAYYYTGIGAG
VLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINE
GIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKEL
HAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFL
LIYASYALAFWYGTSLVISKEYSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYE
VFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVA
LVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTI
AENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARA
LVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGG
VIVEQGNHDELMREKGIYFKLVMTQTAGNEIELGNEACKSKDEIDNLDMSSKDSGSSLIR
RRSTRKSICGPHDQDRKLSTKEALDEDVPPASFWRILKLNSTEWPYFVVGIFCAIINGGL
QPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEIL
TKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLG
TGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENF
RTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLV
TQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQ
GLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLE
RFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEE
IVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATS
ALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQK
GIYFSMVSVQAGAKRS
NT seq
3831 nt
NT seq
+upstream
nt +downstream
nt
atggaacttgaagaggaccttaagggaagagcagacaagaacttctcaaagatgggcaaa
aagagtaaaaaggagaagaaagaaaagaaaccagcagtcagtgtgcttacaatgtttcgt
tatgcaggttggctggacaggttgtacatgctggtgggaactctggctgctattatccat
ggagtggcgctcccacttatgatgctgatctttggtgacatgacagatagctttgcaagt
gtaggaaacgtctctaaaaacagtactaatatgagtgaggccgataaaagagccatgttt
gccaaactggaggaagaaatgaccacgtacgcctactattacaccgggattggtgctggt
gtgctcatagttgcctacatccaggtttcattttggtgcctggcagctggaagacagata
cacaagatcaggcagaagttttttcatgctataatgaatcaggagataggctggtttgat
gtgcatgacgttggggagctcaacacccggctcacagatgatgtttccaaaattaatgaa
ggaattggtgacaaaatcggaatgttcttccaggcaatggcaacattttttggtggtttt
ataataggatttacccgtggctggaagctaacccttgtgattttggccatcagccctgtt
cttggactgtcagctggtatttgggcaaagatattgtcttcatttactgataaggaactc
catgcttatgcaaaagctggagcagttgctgaagaagtcttagcagccatcagaactgtg
attgcgtttggaggacaaaagaaggaacttgaaaggtacaataacaacttggaagaagct
aaaaggctggggataaagaaagctatcacggccaacatctccatgggtgcagcttttctc
cttatctatgcatcatatgctctggcattctggtatgggacttccttggtcatctccaaa
gaatactctattggacaagtgctcactgtcttcttttccgtgttaattggagcattcagt
gttggacaggcatctccaaatattgaagccttcgccaatgcacgaggagcagcttatgaa
gtcttcaaaataattgataataagcccagtatagacagcttctcaaagagtgggcacaaa
ccagacaacatacaaggaaatctggaatttaagaatattcacttcagttacccatctcga
aaagaagttcagatcttgaagggcctcaatctgaaggtgaagagcggacagacggtggcc
ctggttggcaacagtggctgtggaaaaagcacaactgtccagctgatgcaaaggctctac
gaccccctagatggcatggtcagtatcgacggacaggacatcagaaccatcaatgtgagg
tatctgagggagatcattggtgtggtgagtcaggaacctgtgctgtttgccaccacgatc
gccgagaacattcgctatggccgagaagatgtcaccatggatgagattgagaaagctgtc
aaggaagccaatgcctatgacttcatcatgaaactgccccaccaatttgacaccctggtt
ggtgagagaggggcgcagctgagtgggggacagaaacagagaatcgccattgcccgggcc
ctggtccgcaatcccaagatccttttgttggacgaggccacctcagccctggatacagaa
agtgaagctgtggttcaggccgcactggataaggctagagaaggccggaccaccattgtg
atagctcatcgcttgtctaccgttcgtaatgctgacgtcattgctggttttgatggtggt
gtcattgtggagcaaggaaatcatgatgagctcatgagagaaaagggcatttacttcaaa
cttgtcatgacacagacagcaggaaatgaaattgaattaggaaatgaagcttgtaaatct
aaggatgaaattgataatttagacatgtcttcaaaagattcaggatccagtctaataaga
agaagatcaactcgcaaaagcatctgtggaccacatgaccaagacaggaagcttagtacc
aaagaggccctggatgaagatgtacctccagcttccttttggcggatcctgaagttgaat
tcaactgaatggccttattttgtggttggtatattctgtgccataataaatggaggctta
cagccagcattctccgtaatattttcaaaagttgtaggggtttttacaaatggtggcccc
cctgaaacccagcggcagaacagcaacttgttttccttgttgtttctgatccttgggatc
atttctttcattacattttttcttcagggcttcacatttggcaaagctggagagatcctc
accaagcgactccgatacatggttttcaaatccatgctgagacaggatgtgagctggttt
gatgaccctaaaaacaccaccggagcactgaccaccaggctcgccaacgatgctgctcaa
gtgaaaggggctacagggtctaggcttgctgtgattttccagaacatagcaaatcttggg
acaggaatcatcatatccctaatctatggctggcaactaacacttttactcttagcaatt
gtacccatcattgcgatagcaggagtggttgaaatgaaaatgttgtctggacaagcactg
aaagataagaaggaactagaaggttctggaaagattgctacggaagcaattgaaaacttc
cgcactgttgtctctttgactcgggagcagaagtttgaaaccatgtatgcccagagcttg
cagataccatacagaaatgcgatgaagaaagcacacgtgtttgggatcacgttctccttc
acccaggccatgatgtatttttcttatgctgcttgtttccggttcggtgcctacttggtg
acacaacaactcatgacttttgaaaatgttctgttagtattctcagctattgtctttggt
gccatggcagtggggcaggtcagttcattcgctcctgactatgcgaaagccacagtgtca
gcatcccacatcatcaggatcattgagaaaacccccgagattgacagctacagcacgcaa
ggcctaaagccgaatatgttggaaggaaatgtgcaatttagtggagtcgtgttcaactat
cccacccgacccagcatcccagtgcttcaggggctgagccttgaggtgaagaagggccag
acgctggccctggtgggcagcagtggctgcgggaagagcacagtggtccagctgctcgag
cgcttctacgaccccatggctggatcagtgtttctagatggcaaagaaataaagcaactg
aatgtccagtggctccgagcacagctgggcattgtgtcccaagagcccattctctttgac
tgcagcatcgcagagaacattgcctacggagacaacagccgggtcgtgtcttatgaggag
attgtgagggcagccaaggaggccaacatccaccagttcatcgactcgctacctgataaa
tacaacaccagagtaggagacaaaggcactcagctgtcgggtgggcagaagcagcgcatc
gccatcgcacgcgccctcgtcagacagcctcacattttacttctggacgaagcaacatca
gctctggatacagaaagtgaaaaggttgtccaggaagcgctggacaaagccagggaaggc
cgcacctgcattgtgatcgctcaccgcctgtccaccatccagaacgcggacttgatcgtg
gtgattcagaacggcaaggtcaaggagcacggcacccaccagcagctgctggcgcagaag
ggcatctacttctcaatggtcagtgtgcaggctggagcaaagcgctcatga
DBGET
integrated database retrieval system
