Mus musculus (house mouse): 18747
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Entry
18747 CDS
T01002
Symbol
Prkaca, PKCD, Pkaca
Name
(RefSeq) protein kinase, cAMP dependent, catalytic, alpha
KO
K04345
protein kinase A [EC:
2.7.11.11
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01522
Endocrine resistance
mmu04010
MAPK signaling pathway
mmu04014
Ras signaling pathway
mmu04020
Calcium signaling pathway
mmu04024
cAMP signaling pathway
mmu04062
Chemokine signaling pathway
mmu04114
Oocyte meiosis
mmu04140
Autophagy - animal
mmu04211
Longevity regulating pathway
mmu04213
Longevity regulating pathway - multiple species
mmu04261
Adrenergic signaling in cardiomyocytes
mmu04270
Vascular smooth muscle contraction
mmu04310
Wnt signaling pathway
mmu04340
Hedgehog signaling pathway
mmu04371
Apelin signaling pathway
mmu04530
Tight junction
mmu04540
Gap junction
mmu04611
Platelet activation
mmu04713
Circadian entrainment
mmu04714
Thermogenesis
mmu04720
Long-term potentiation
mmu04723
Retrograde endocannabinoid signaling
mmu04724
Glutamatergic synapse
mmu04725
Cholinergic synapse
mmu04726
Serotonergic synapse
mmu04727
GABAergic synapse
mmu04728
Dopaminergic synapse
mmu04740
Olfactory transduction
mmu04742
Taste transduction
mmu04750
Inflammatory mediator regulation of TRP channels
mmu04910
Insulin signaling pathway
mmu04911
Insulin secretion
mmu04912
GnRH signaling pathway
mmu04913
Ovarian steroidogenesis
mmu04914
Progesterone-mediated oocyte maturation
mmu04915
Estrogen signaling pathway
mmu04916
Melanogenesis
mmu04918
Thyroid hormone synthesis
mmu04919
Thyroid hormone signaling pathway
mmu04921
Oxytocin signaling pathway
mmu04922
Glucagon signaling pathway
mmu04923
Regulation of lipolysis in adipocytes
mmu04924
Renin secretion
mmu04925
Aldosterone synthesis and secretion
mmu04926
Relaxin signaling pathway
mmu04927
Cortisol synthesis and secretion
mmu04928
Parathyroid hormone synthesis, secretion and action
mmu04934
Cushing syndrome
mmu04935
Growth hormone synthesis, secretion and action
mmu04961
Endocrine and other factor-regulated calcium reabsorption
mmu04962
Vasopressin-regulated water reabsorption
mmu04970
Salivary secretion
mmu04971
Gastric acid secretion
mmu04976
Bile secretion
mmu05012
Parkinson disease
mmu05020
Prion disease
mmu05030
Cocaine addiction
mmu05031
Amphetamine addiction
mmu05032
Morphine addiction
mmu05034
Alcoholism
mmu05146
Amoebiasis
mmu05163
Human cytomegalovirus infection
mmu05165
Human papillomavirus infection
mmu05166
Human T-cell leukemia virus 1 infection
mmu05200
Pathways in cancer
mmu05203
Viral carcinogenesis
mmu05205
Proteoglycans in cancer
mmu05207
Chemical carcinogenesis - receptor activation
mmu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
18747 (Prkaca)
04014 Ras signaling pathway
18747 (Prkaca)
04310 Wnt signaling pathway
18747 (Prkaca)
04340 Hedgehog signaling pathway
18747 (Prkaca)
04371 Apelin signaling pathway
18747 (Prkaca)
04020 Calcium signaling pathway
18747 (Prkaca)
04024 cAMP signaling pathway
18747 (Prkaca)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
18747 (Prkaca)
09143 Cell growth and death
04114 Oocyte meiosis
18747 (Prkaca)
09144 Cellular community - eukaryotes
04530 Tight junction
18747 (Prkaca)
04540 Gap junction
18747 (Prkaca)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
18747 (Prkaca)
04062 Chemokine signaling pathway
18747 (Prkaca)
09152 Endocrine system
04911 Insulin secretion
18747 (Prkaca)
04910 Insulin signaling pathway
18747 (Prkaca)
04922 Glucagon signaling pathway
18747 (Prkaca)
04923 Regulation of lipolysis in adipocytes
18747 (Prkaca)
04912 GnRH signaling pathway
18747 (Prkaca)
04913 Ovarian steroidogenesis
18747 (Prkaca)
04915 Estrogen signaling pathway
18747 (Prkaca)
04914 Progesterone-mediated oocyte maturation
18747 (Prkaca)
04921 Oxytocin signaling pathway
18747 (Prkaca)
04926 Relaxin signaling pathway
18747 (Prkaca)
04935 Growth hormone synthesis, secretion and action
18747 (Prkaca)
04918 Thyroid hormone synthesis
18747 (Prkaca)
04919 Thyroid hormone signaling pathway
18747 (Prkaca)
04928 Parathyroid hormone synthesis, secretion and action
18747 (Prkaca)
04916 Melanogenesis
18747 (Prkaca)
04924 Renin secretion
18747 (Prkaca)
04925 Aldosterone synthesis and secretion
18747 (Prkaca)
04927 Cortisol synthesis and secretion
18747 (Prkaca)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
18747 (Prkaca)
04270 Vascular smooth muscle contraction
18747 (Prkaca)
09154 Digestive system
04970 Salivary secretion
18747 (Prkaca)
04971 Gastric acid secretion
18747 (Prkaca)
04976 Bile secretion
18747 (Prkaca)
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
18747 (Prkaca)
04961 Endocrine and other factor-regulated calcium reabsorption
18747 (Prkaca)
09156 Nervous system
04724 Glutamatergic synapse
18747 (Prkaca)
04727 GABAergic synapse
18747 (Prkaca)
04725 Cholinergic synapse
18747 (Prkaca)
04728 Dopaminergic synapse
18747 (Prkaca)
04726 Serotonergic synapse
18747 (Prkaca)
04720 Long-term potentiation
18747 (Prkaca)
04723 Retrograde endocannabinoid signaling
18747 (Prkaca)
09157 Sensory system
04740 Olfactory transduction
18747 (Prkaca)
04742 Taste transduction
18747 (Prkaca)
04750 Inflammatory mediator regulation of TRP channels
18747 (Prkaca)
09149 Aging
04211 Longevity regulating pathway
18747 (Prkaca)
04213 Longevity regulating pathway - multiple species
18747 (Prkaca)
09159 Environmental adaptation
04713 Circadian entrainment
18747 (Prkaca)
04714 Thermogenesis
18747 (Prkaca)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
18747 (Prkaca)
05205 Proteoglycans in cancer
18747 (Prkaca)
05207 Chemical carcinogenesis - receptor activation
18747 (Prkaca)
05203 Viral carcinogenesis
18747 (Prkaca)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
18747 (Prkaca)
05163 Human cytomegalovirus infection
18747 (Prkaca)
05165 Human papillomavirus infection
18747 (Prkaca)
09174 Infectious disease: parasitic
05146 Amoebiasis
18747 (Prkaca)
09164 Neurodegenerative disease
05012 Parkinson disease
18747 (Prkaca)
05020 Prion disease
18747 (Prkaca)
09165 Substance dependence
05030 Cocaine addiction
18747 (Prkaca)
05031 Amphetamine addiction
18747 (Prkaca)
05032 Morphine addiction
18747 (Prkaca)
05034 Alcoholism
18747 (Prkaca)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
18747 (Prkaca)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
18747 (Prkaca)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
18747 (Prkaca)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
18747 (Prkaca)
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
mmu03019
]
18747 (Prkaca)
03036 Chromosome and associated proteins [BR:
mmu03036
]
18747 (Prkaca)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.11 cAMP-dependent protein kinase
18747 (Prkaca)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: AGC group
PKA family
18747 (Prkaca)
Messenger RNA biogenesis [BR:
mmu03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
18747 (Prkaca)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
18747 (Prkaca)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Pkinase_C
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
18747
NCBI-ProteinID:
NP_032880
MGI:
97592
Ensembl:
ENSMUSG00000005469
UniProt:
P05132
Structure
PDB
LinkDB
All DBs
Position
8:84699607..84723073
Genome browser
AA seq
351 aa
AA seq
DB search
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVML
VKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
NT seq
1056 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagcgtgaaagagttccta
gccaaagccaaggaagatttcctgaaaaaatgggagaccccttctcagaatacagcccag
ttggatcagtttgatagaatcaagacccttggcaccggctcctttgggcgagtgatgctg
gtgaagcacaaggagagtgggaaccactacgccatgaagatcttagacaagcagaaggtg
gtgaagctaaagcagatcgagcacactctgaatgagaagcgcatcctgcaggccgtcaac
ttcccgttcctggtcaaacttgaattctccttcaaggacaactcaaacctgtacatggtc
atggagtatgtagctggtggcgagatgttctcccacctacggcggattggaaggttcagc
gagccccatgcccgtttctacgcggcgcagatcgtcctgacctttgagtatctgcactcc
ctggacctcatctaccgggacctgaagcccgagaatcttctcatcgaccagcagggctat
attcaggtgacagacttcggttttgccaagcgtgtgaaaggccgtacttggaccttgtgt
gggacccctgagtacttggcccccgagattatcctgagcaaaggctacaacaaggctgtg
gactggtgggctctcggagtcctcatctacgagatggctgctggttacccacccttcttc
gctgaccagcctatccagatctatgagaaaatcgtctctgggaaggtgcggttcccatcc
cacttcagctctgacttgaaggacctgctgcggaaccttctgcaggtggatctcaccaag
cgctttgggaacctcaagaacggggtcaatgacatcaagaaccacaagtggtttgccacg
actgactggattgccatctatcagagaaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacgagtaactttgacgactatgaggaggaagagatccgggtctccatc
aatgagaagtgtggcaaggagtttactgagttttag
DBGET
integrated database retrieval system