KEGG   Mus musculus (mouse): 19206Help
Entry
19206             CDS       T01002                                 

Gene name
Ptch1, A230106A15Rik, Ptc, Ptc1, Ptch, mes, wig
Definition
(RefSeq) patched 1
  KO
K06225  patched 1
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04024  cAMP signaling pathway
mmu04340  Hedgehog signaling pathway
mmu04360  Axon guidance
mmu05200  Pathways in cancer
mmu05205  Proteoglycans in cancer
mmu05217  Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    19206 (Ptch1)
   04024 cAMP signaling pathway
    19206 (Ptch1)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    19206 (Ptch1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    19206 (Ptch1)
   05205 Proteoglycans in cancer
    19206 (Ptch1)
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    19206 (Ptch1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Patched Sterol-sensing
Motif
Other DBs
NCBI-GeneID: 19206
NCBI-ProteinID: NP_032983
MGI: 105373
Ensembl: ENSMUSG00000021466
Vega: OTTMUSG00000050865
UniProt: Q61115 Q3UUD4 Q3TQB0 Q5R252
LinkDB All DBs
Structure
PDB: 

Position
13 B3; 13 32.8 cM
AA seq 1434 aa AA seqDB search
MASAGNAAGALGRQAGGGRRRRTGGPHRAAPDRDYLHRPSYCDAAFALEQISKGKATGRK
APLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGG
RVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYN
RQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPL
RWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNST
KPLDVALVLNGGCQGLSRKYMHWQEELIVGGTVKNATGKLVSAHALQTMFQLMTPKQMYE
HFRGYDYVSHINWNEDRAAAILEAWQRTYVEVVHQSVAPNSTQKVLPFTTTTLDDILKSF
SDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGIS
FNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSIS
NVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCF
TSPCVSRVIQVEPQAYTEPHSNTRYSPPPPYTSHSFAHETHITMQSTVQLRTEYDPHTHV
YYTTAEPRSEISVQPVTVTQDNLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSS
FAEKHYAPFLLKPKAKVVVILLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQ
FKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPQMWLHYFRDWLQG
LQDAFDSDWETGRIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGII
NPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQF
PFYLNGLRDTSDFVEAIEKVRVICNNYTSLGLSSYPNGYPFLFWEQYISLRHWLLLSISV
VLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGV
EFTVHVALAFLTAIGDKNHRAMLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFA
VLAILTVLGVLNGLVLLPVLLSFFGPCPEVSPANGLNRLPTPSPEPPPSVVRFAVPPGHT
NNGSDSSDSEYSSQTTVSGISEELRQYEAQQGAGGPAHQVIVEATENPVFARSTVVHPDS
RHQPPLTPRQQPHLDSGSLSPGRQGQQPRRDPPREGLRPPPYRPRRDAFEISTEGHSGPS
NRDRSGPRGARSHNPRNPTSTAMGSSVPSYCQPITTVTASASVTVAVHPPPGPGRNPRGG
PCPGYESYPETDHGVFEDPHVPFHVRCERRDSKVEVIELQDVECEERPWGSSSN
NT seq 4305 nt NT seq  +upstreamnt  +downstreamnt
atggcctcggctggtaacgccgccggggccctgggcaggcaggccggcggcgggaggcgc
agacggaccgggggaccgcaccgcgccgcgccggaccgggactatctgcaccggcccagc
tactgcgacgccgccttcgctctggagcagatttccaaggggaaggctactggccggaaa
gcgccgctgtggctgagagcgaagtttcagagactcttatttaaactgggttgttacatt
caaaagaactgcggcaagtttttggttgtgggtctcctcatatttggggccttcgctgtg
ggattaaaggcagctaatctcgagaccaacgtggaggagctgtgggtggaagttggtgga
cgagtgagtcgagaattaaattatacccgtcagaagataggagaagaggctatgtttaat
cctcaactcatgatacagactccaaaagaagaaggcgctaatgttctgaccacagaggct
ctcctgcaacacctggactcagcactccaggccagtcgtgtgcacgtctacatgtataac
aggcaatggaagttggaacatttgtgctacaaatcaggggaacttatcacggagacaggt
tacatggatcagataatagaatacctttacccttgcttaatcattacacctttggactgc
ttctgggaaggggcaaagctacagtccgggacagcatacctcctaggtaagcctccttta
cggtggacaaactttgaccccttggaattcctagaagagttaaagaaaataaactaccaa
gtggacagctgggaggaaatgctgaataaagccgaagttggccatgggtacatggaccgg
ccttgcctcaacccagccgacccagattgccctgccacagcccctaacaaaaattcaacc
aaacctcttgatgtggcccttgttttgaatggtggatgtcaaggtttatccaggaagtat
atgcattggcaggaggagttgattgtgggtggtaccgtcaagaatgccactggaaaactt
gtcagcgctcacgccctgcaaaccatgttccagttaatgactcccaagcaaatgtatgaa
cacttcaggggctacgactatgtctctcacatcaactggaatgaagacagggcagccgcc
atcctggaggcctggcagaggacttacgtggaggtggttcatcaaagtgtcgccccaaac
tccactcaaaaggtgcttcccttcacaaccacgaccctggacgacatcctaaaatccttc
tctgatgtcagtgtcatccgagtggccagcggctacctactgatgcttgcctatgcctgt
ttaaccatgctgcgctgggactgctccaagtcccagggtgccgtggggctggctggcgtc
ctgttggttgcgctgtcagtggctgcaggattgggcctctgctccttgattggcatttct
tttaatgctgcgacaactcaggttttgccgtttcttgctcttggtgttggtgtggatgat
gtcttcctcctggcccatgcattcagtgaaacaggacagaataagaggattccatttgag
gacaggactggggagtgcctcaagcgcaccggagccagcgtggccctcacctccatcagc
aatgtcaccgccttcttcatggccgcattgatccctatccctgccctgcgagcgttctcc
ctccaggctgctgtggtggtggtattcaattttgctatggttctgctcatttttcctgca
attctcagcatggatttatacagacgtgaggacagaagattggatattttctgctgtttc
acaagcccctgtgtcagcagggtgattcaagttgagccacaggcctacacagagcctcac
agtaacacccggtacagccccccacccccatacaccagccacagcttcgcccacgaaacc
catatcactatgcagtccaccgttcagctccgcacagagtatgaccctcacacgcacgtg
tactacaccaccgccgagccacgctctgagatctctgtacagcctgttaccgtcacccag
gacaacctcagctgtcagagtcccgagagcaccagctctaccagggacctgctctcccag
ttctcagactccagcctccactgcctcgagcccccctgcaccaagtggacactctcttcg
tttgcagagaagcactatgctcctttcctcctgaaacccaaagccaaggttgtggtaatc
cttcttttcctgggcttgctgggggtcagcctttatgggaccacccgagtgagagacggg
ctggacctcacggacattgttccccgggaaaccagagaatatgacttcatagctgcccag
ttcaagtacttctctttctacaacatgtatatagtcacccagaaagcagactacccgaat
atccagcacctactttacgaccttcataagagtttcagcaatgtgaagtatgtcatgctg
gaggagaacaagcaacttccccaaatgtggctgcactactttagagactggcttcaagga
cttcaggatgcatttgacagtgactgggaaactgggaggatcatgccaaacaattataaa
aatggatcagatgacggggtcctcgcttacaaactcctggtgcagactggcagccgagac
aagcccatcgacattagtcagttgactaaacagcgtctggtagacgcagatggcatcatt
aatccgagcgctttctacatctacctgaccgcttgggtcagcaacgaccctgtagcttac
gctgcctcccaggccaacatccggcctcaccggccggagtgggtccatgacaaagccgac
tacatgccagagaccaggctgagaatcccagcagcagagcccatcgagtacgctcagttc
cctttctacctcaacggcctacgagacacctcagactttgtggaagccatagaaaaagtg
agagtcatctgtaacaactatacgagcctgggactgtccagctaccccaatggctacccc
ttcctgttctgggagcaatacatcagcctgcgccactggctgctgctatccatcagcgtg
gtgctggcctgcacgtttctagtgtgcgcagtcttcctcctgaacccctggacggccggg
atcattgtcatggtcctggctctgatgaccgttgagctctttggcatgatgggcctcatt
gggatcaagctgagtgctgtgcctgtggtcatcctgattgcatctgttggcatcggagtg
gagttcaccgtccacgtggctttggcctttctgacagccattggggacaagaaccacagg
gctatgctcgctctggagcacatgtttgctcccgttctggacggtgctgtgtccactctg
ctgggtgtactgatgcttgcagggtccgaatttgatttcattgtcagatacttctttgcc
gtcctggccattctcaccgtcttgggggttctcaatggactggttctgctgcctgtcctc
ttatccttctttggaccgtgtcctgaggtgtctccagccaatggcctaaaccgactgccc
actccttcgcctgagccgcctccaagtgtcgtccggtttgccgtgcctcctggtcacacg
aacaatgggtctgattcctccgactcggagtacagctctcagaccacggtgtctggcatc
agtgaggagctcaggcaatacgaagcacagcagggtgccggaggccctgcccaccaagtg
attgtggaagccacagaaaaccctgtctttgcccggtccactgtggtccatccggactcc
agacatcagcctcccttgacccctcggcaacagccccacctggactctggctccttgtcc
cctggacggcaaggccagcagcctcgaagggatccccctagagaaggcttgcggccaccc
ccctacagaccgcgcagagacgcttttgaaatttctactgaagggcattctggccctagc
aatagggaccgctcagggccccgtggggcccgttctcacaaccctcggaacccaacgtcc
accgccatgggcagctctgtgcccagctactgccagcccatcaccactgtgacggcttct
gcttcggtgactgttgctgtgcatcccccgcctggacctgggcgcaacccccgagggggg
ccctgtccaggctatgagagctaccctgagactgatcacggggtatttgaggatcctcat
gtgccttttcatgtcaggtgtgagaggagggactcaaaggtggaggtcatagagctacag
gacgtggaatgtgaggagaggccgtgggggagcagctccaactga

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