KEGG   Mus musculus (mouse): 20181
Entry
20181             CDS       T01002                                 

Gene name
Rxra, 9530071D11Rik, Nr2b1, RXR, RXRalpha1
Definition
(RefSeq) retinoid X receptor alpha
  KO
K08524  retinoid X receptor alpha
Organism
mmu  Mus musculus (mouse)
Pathway
mmu03320  PPAR signaling pathway
mmu04151  PI3K-Akt signaling pathway
mmu04659  Th17 cell differentiation
mmu04919  Thyroid hormone signaling pathway
mmu04920  Adipocytokine signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu04932  Non-alcoholic fatty liver disease
mmu04976  Bile secretion
mmu05160  Hepatitis C
mmu05200  Pathways in cancer
mmu05202  Transcriptional misregulation in cancer
mmu05216  Thyroid cancer
mmu05222  Small cell lung cancer
mmu05223  Non-small cell lung cancer
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    20181 (Rxra)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    20181 (Rxra)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    20181 (Rxra)
   03320 PPAR signaling pathway
    20181 (Rxra)
   04919 Thyroid hormone signaling pathway
    20181 (Rxra)
   04928 Parathyroid hormone synthesis, secretion and action
    20181 (Rxra)
  09154 Digestive system
   04976 Bile secretion
    20181 (Rxra)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20181 (Rxra)
   05202 Transcriptional misregulation in cancer
    20181 (Rxra)
  09162 Cancer: specific types
   05226 Gastric cancer
    20181 (Rxra)
   05216 Thyroid cancer
    20181 (Rxra)
   05222 Small cell lung cancer
    20181 (Rxra)
   05223 Non-small cell lung cancer
    20181 (Rxra)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    20181 (Rxra)
  09172 Infectious disease: viral
   05160 Hepatitis C
    20181 (Rxra)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20181 (Rxra)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:mmu03310]
    20181 (Rxra)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    20181 (Rxra)
Nuclear receptors [BR:mmu03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   20181 (Rxra)
SSDB
Motif
Pfam: Nuc_recep-AF1 Hormone_recep zf-C4
Other DBs
NCBI-GeneID: 20181
NCBI-ProteinID: NP_035435
MGI: 98214
Ensembl: ENSMUSG00000015846
Vega: OTTMUSG00000012047
UniProt: P28700 A2AJP1 Q3UMU4
LinkDB
Structure
PDB: 
1DKF 3A9E 1XDK

Position
2 A3; 2 19.38 cM
AA seq 467 aa
MDTKHFLPLDFSTQVNSSSLNSPTGRGSMAVPSLHPSLGPGIGSPLGSPGQLHSPISTLS
SPINGMGPPFSVISSPMGPHSMSVPTTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNG
VLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNK
DCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKI
LEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLD
DQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVS
KMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRF
AKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT
NT seq 1404 nt   +upstreamnt  +downstreamnt
atggacaccaaacatttcctgccgctcgacttctctacccaggtgaactcttcgtccctc
aactctccaacgggtcgaggctccatggctgtcccctcgctgcacccctccttgggtccg
ggaatcggctctccactgggctcgcctgggcagctgcactctcctatcagcaccctgagc
tcccccatcaatggcatgggtccgcccttctctgtcatcagctcccccatgggcccgcac
tccatgtcggtacccaccacacccacattgggcttcgggactggtagcccccagctcaat
tcacccatgaaccctgtgagcagcactgaggatatcaagccgccactaggcctcaatggc
gtcctcaaggttcctgcccatccctcaggaaatatggcctccttcaccaagcacatctgt
gctatctgtggggaccgctcctcaggcaaacactatggggtatacagttgtgagggctgc
aagggcttcttcaagaggacagtacgcaaagacctgacctacacctgccgagacaacaag
gactgcctgatcgacaagagacagcggaaccggtgtcagtactgccgctaccagaagtgc
ctggccatgggcatgaagcgggaagctgtgcaggaggagcggcagcggggcaaggaccgg
aatgagaacgaggtggagtccaccagcagtgccaacgaggacatgcctgtagagaagatt
ctggaagccgagcttgctgtcgagcccaagactgagacatacgtggaggcaaacatgggg
ctgaaccccagctcaccaaatgaccctgttaccaacatctgtcaagcagcagacaagcag
ctcttcactcttgtggagtgggccaagaggatcccacacttttctgagctgcccctagac
gaccaggtcatcctgctacgggcaggctggaacgagctgctgatcgcctccttctcccac
cgctccatagctgtgaaagatgggattctcctggccaccggcctgcacgtacaccggaac
agcgctcacagtgctggggtgggcgccatctttgacagggtgctaacagagctggtgtct
aagatgcgtgacatgcagatggacaagacggagctgggctgcctgcgagccattgtcctg
ttcaaccctgactctaaggggctctcaaaccctgctgaggtggaggcgttgagggagaag
gtgtatgcgtcactagaagcgtactgcaaacacaagtaccctgagcagccgggcaggttt
gccaagctgctgctccgcctgcctgcactgcgttccatcgggctcaagtgcctggagcac
ctgttcttcttcaagctcatcggggacacgcccatcgacaccttcctcatggagatgctg
gaggcaccacatcaagccacctag

KEGG   Mus musculus (mouse): 20182
Entry
20182             CDS       T01002                                 

Gene name
Rxrb, AL023085, H-2R, H-2RIIBP, Nr2, Nr2b2, RCo, RCoR-1, Ru, Rub
Definition
(RefSeq) retinoid X receptor beta
  KO
K08525  retinoid X receptor beta
Organism
mmu  Mus musculus (mouse)
Pathway
mmu03320  PPAR signaling pathway
mmu04659  Th17 cell differentiation
mmu04919  Thyroid hormone signaling pathway
mmu04920  Adipocytokine signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu05200  Pathways in cancer
mmu05202  Transcriptional misregulation in cancer
mmu05216  Thyroid cancer
mmu05222  Small cell lung cancer
mmu05223  Non-small cell lung cancer
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    20182 (Rxrb)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    20182 (Rxrb)
   03320 PPAR signaling pathway
    20182 (Rxrb)
   04919 Thyroid hormone signaling pathway
    20182 (Rxrb)
   04928 Parathyroid hormone synthesis, secretion and action
    20182 (Rxrb)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20182 (Rxrb)
   05202 Transcriptional misregulation in cancer
    20182 (Rxrb)
  09162 Cancer: specific types
   05226 Gastric cancer
    20182 (Rxrb)
   05216 Thyroid cancer
    20182 (Rxrb)
   05222 Small cell lung cancer
    20182 (Rxrb)
   05223 Non-small cell lung cancer
    20182 (Rxrb)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20182 (Rxrb)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:mmu03310]
    20182 (Rxrb)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    20182 (Rxrb)
Nuclear receptors [BR:mmu03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   20182 (Rxrb)
SSDB
Motif
Pfam: Hormone_recep zf-C4 Nuc_recep-AF1
Other DBs
NCBI-GeneID: 20182
NCBI-ProteinID: NP_035436
MGI: 98215
Ensembl: ENSMUSG00000039656
Vega: OTTMUSG00000037107
UniProt: P28704
LinkDB
Position
17 B1; 17 17.98 cM
AA seq 520 aa
MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEP
EPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPF
PVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPP
PPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQ
RNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQ
KSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLR
AGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRM
DKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRL
PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgtcttgggccactcgtccgcccttcctcccgccgcggcatgccgcggggcagtgtggg
ccggtgggggtgagaaaagagatgcattgtggggtcgcgtcccggtggcggcggcggcgg
ccctggctggatcccgcggcggcggcggcggcggccggagagcagcaagccctggagccg
gagccgggggaggctggccgggacgggatgggcgacagcgggcgggattcccgaagccca
gacagctcctccccaaatcccctttctcaggggatccgtccgtcttctcctcctggccca
cctcttaccccttcagcacctccacctccaatgccacccccgccactgggctcccccttc
ccagtcatcagttcttccatggggtcccctggtctgccccctccggctcccccaggattc
tccgggcctgtcagcagccctcagatcaactccacagtgtcgctccctgggggtgggtct
ggcccccctgaagatgtgaagccaccggtcttaggggtccggggcctgcactgtccaccc
cctccaggtggtcctggggctggcaaacggctctgtgcaatctgcggggaccgaagctca
ggcaagcactatggggtttacagctgcgagggctgcaagggtttcttcaagcgcaccatt
cggaaggacctgacctactcgtgtcgtgataacaaagactgtacagtggacaagcgccag
cggaatcgctgtcagtactgtcgctatcagaagtgcctggccactggcatgaaaagggag
gcggttcaggaggagcgtcaacgggggaaggacaaagacggggatggagatggggctggg
ggagcccctgaggagatgcctgtggacaggatcctggaggcagagcttgctgtggagcag
aagagtgaccaaggcgttgagggtcctggggccaccgggggtggtggcagcagcccaaat
gacccagtgactaacatctgccaggcagctgacaaacagctgttcacactcgttgagtgg
gcaaagaggatcccgcacttctcctccctacctctggacgatcaggtcatactgctgcgg
gcaggctggaacgagctcctcattgcgtccttctcccatcggtccattgatgtccgagat
ggcatcctcctggccacgggtcttcatgtgcacagaaactcagcccattccgcaggcgtg
ggagccatctttgatcgggtgctgacagagctagtgtccaaaatgcgtgacatgaggatg
gacaagacagagcttggctgcctgcgggcaatcatactgtttaatccagacgccaagggc
ctctccaaccctggagaggtggagatccttcgggagaaggtgtacgcctcactggagacc
tattgcaagcagaagtaccctgagcagcagggccggtttgccaagctgctgttacgtctt
cctgccctccgctccatcggcctcaagtgtctggagcacctgttcttcttcaagctcatt
ggcgacacccccattgacaccttcctcatggagatgcttgaggctccccaccagctagcc
tga

KEGG   Mus musculus (mouse): 20183
Entry
20183             CDS       T01002                                 

Gene name
Rxrg, Nr2, Nr2b3
Definition
(RefSeq) retinoid X receptor gamma
  KO
K08526  retinoid X receptor gamma
Organism
mmu  Mus musculus (mouse)
Pathway
mmu03320  PPAR signaling pathway
mmu04659  Th17 cell differentiation
mmu04919  Thyroid hormone signaling pathway
mmu04920  Adipocytokine signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu05200  Pathways in cancer
mmu05202  Transcriptional misregulation in cancer
mmu05216  Thyroid cancer
mmu05222  Small cell lung cancer
mmu05223  Non-small cell lung cancer
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    20183 (Rxrg)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    20183 (Rxrg)
   03320 PPAR signaling pathway
    20183 (Rxrg)
   04919 Thyroid hormone signaling pathway
    20183 (Rxrg)
   04928 Parathyroid hormone synthesis, secretion and action
    20183 (Rxrg)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20183 (Rxrg)
   05202 Transcriptional misregulation in cancer
    20183 (Rxrg)
  09162 Cancer: specific types
   05226 Gastric cancer
    20183 (Rxrg)
   05216 Thyroid cancer
    20183 (Rxrg)
   05222 Small cell lung cancer
    20183 (Rxrg)
   05223 Non-small cell lung cancer
    20183 (Rxrg)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20183 (Rxrg)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:mmu03310]
    20183 (Rxrg)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    20183 (Rxrg)
Nuclear receptors [BR:mmu03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   20183 (Rxrg)
SSDB
Motif
Pfam: Nuc_recep-AF1 Hormone_recep zf-C4
Other DBs
NCBI-GeneID: 20183
NCBI-ProteinID: NP_033133
MGI: 98216
Ensembl: ENSMUSG00000015843
Vega: OTTMUSG00000022560
UniProt: P28705
LinkDB
Position
1 H2.3; 1 74.99 cM
AA seq 463 aa
MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRTLSAVG
TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG
IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSSHEDMPVERIL
EAELAVEPKTESYGDMNVENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
LRLPALRSIGLKCLEHLFFFKLIGDTPIDSFLMEMLETPLQIT
NT seq 1392 nt   +upstreamnt  +downstreamnt
atgtatggaaattattcccacttcatgaagtttcccaccggctttggtggctcccctggt
cacactggctcgacgtccatgagcccttcagtagccttgcccacggggaagccaatggac
agccaccccagctacacagacaccccagtgagtgcccctcggacgctgagtgctgtggga
acccccctcaatgctcttggctctccgtatagagtcatcacttctgccatgggtccaccc
tcaggagcactggcagctcctccaggaatcaacttggtggctccacccagctcccagcta
aatgtggtcaacagtgtcagcagctctgaggacatcaagcccttaccaggtctgcctggg
attggaaatatgaactacccatccaccagccctgggtctctggtgaaacacatctgtgcc
atctgtggggacagatcctcagggaagcactacggtgtgtacagctgtgaaggttgcaaa
ggcttcttcaaaaggaccatcaggaaagatctcatctacacctgtcgggataacaaagat
tgtctcatcgacaagcgccagcgcaaccgctgccagtactgtcgctaccagaagtgcctg
gtcatgggcatgaagcgggaagctgtgcaagaagaaaggcagaggagccgagagcgagca
gagagtgaggcagaatgtgccagtagtagccacgaagacatgcccgtggagaggattcta
gaagccgaacttgctgtggaaccaaagacagaatcctacggtgacatgaacgtggagaac
tcaacaaatgaccctgttaccaacatatgccatgctgcagataagcaacttttcaccctc
gttgagtgggccaaacgcatcccccacttctcagatctcaccttggaggaccaggtcatt
ctactccgggcagggtggaatgaactgctcattgcctccttctcccaccgctcggtttcc
gtccaggatggcatcctgctggccacgggcctccacgtgcacaggagcagcgctcacagc
gcgggagtcggctccatcttcgacagagtccttacagagttggtgtccaagatgaaagac
atgcagatggataagtcagagctggggtgcctacgggccatcgtgctgtttaacccagat
gccaagggtttatccaacccctctgaggtggagactcttcgagagaaggtttatgccacc
ctggaggcctataccaagcagaagtatccggaacagccaggcaggtttgccaagcttctg
ctgcgtctccctgctctgcgctccatcggcttgaaatgcctggaacacctcttcttcttc
aagctcattggagacactcccatcgacagcttcctcatggagatgttggagaccccactg
cagatcacctga

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