KEGG   Mus musculus (mouse): 22173
Entry
22173             CDS       T01002                                 

Gene name
Tyr, Oc, Oca1, albino, c, skc3, skc35
Definition
(RefSeq) tyrosinase
  KO
K00505  tyrosinase [EC:1.14.18.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00350  Tyrosine metabolism
mmu01100  Metabolic pathways
mmu04916  Melanogenesis
Module
mmu_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    22173 (Tyr)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    22173 (Tyr)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.18.1  tyrosinase
     22173 (Tyr)
SSDB
Motif
Pfam: Tyrosinase LapA_dom
Other DBs
NCBI-GeneID: 22173
NCBI-ProteinID: NP_035791
MGI: 98880
Ensembl: ENSMUSG00000004651
Vega: OTTMUSG00000059417
UniProt: P11344 Q91XK0
LinkDB
Position
7 D3; 7 49.01 cM
AA seq 533 aa
MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILL
SSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIR
RNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMH
YYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRD
AENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRN
PGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQS
SMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGH
NRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLG
AALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
NT seq 1602 nt   +upstreamnt  +downstreamnt
atgttcttggctgttttgtattgccttctgtggagtttccagatctctgatggccatttt
cctcgagcctgtgcctcctctaagaacttgttggcaaaagaatgctgcccaccatggatg
ggtgatgggagtccctgcggccagctttcaggcagaggttcctgccaggatatccttctg
tccagtgcaccatctggacctcagttccccttcaaaggggtggatgaccgtgagtcctgg
ccctctgtgttttataataggacctgccagtgctcaggcaacttcatgggtttcaactgc
ggaaactgtaagtttggatttgggggcccaaattgtacagagaagcgagtcttgattaga
agaaacatttttgatttgagtgtctccgaaaagaataagttcttttcttacctcacttta
gcaaaacatactatcagctcagtctatgtcatccccacaggcacctatggccaaatgaac
aatgggtcaacacccatgtttaatgatatcaacatctacgacctctttgtatggatgcat
tactatgtgtcaagggacacactgcttgggggctctgaaatatggagggacattgatttt
gcccatgaagcaccagggtttctgccttggcacagacttttcttgttattgtgggaacaa
gaaattcgagaactaactggggatgagaacttcactgttccatactgggattggagagat
gcagaaaactgtgacatttgcacagatgagtacttgggaggtcgtcaccctgaaaatcct
aacttactcagcccagcatccttcttctcctcctggcagatcatttgtagcagatcagaa
gagtataatagccatcaggttttatgcgatggaacacctgagggaccactattacgtaat
cctggaaaccatgacaaagccaaaacccccaggctcccatcttcagcagatgtggaattt
tgtctgagtttgacccagtatgaatctggatcaatggatagaactgccaatttcagcttt
agaaacacactggaaggatttgccagtccactcacagggatagcagatccttctcaaagt
agcatgcacaatgccttacatatctttatgaatggaacaatgtcccaagtacagggatcg
gccaacgatcccatttttcttcttcaccatgcttttgtggacagtatttttgaacaatgg
ctgcgaaggcaccgccctcttttggaagtttacccagaagccaatgcacctatcggccat
aacagagactcttacatggttcctttcataccgctctatagaaatggtgatttcttcata
acatccaaggatctgggatatgactacagctacctccaagagtcagatccaggcttttac
agaaattatattgagccttacttggaacaagccagtcgtatctggccatggcttcttggg
gcagcactggtgggagctgttattgctgcagctctctctgggcttagcagtaggctatgc
cttcagaagaagaagaagaagaagcaaccccaggaggaaaggcagccactcctcatggac
aaagacgactaccacagcttgctgtatcagagccatctgtga

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