KEGG   Mus musculus (mouse): 26409Help
Entry
26409             CDS       T01002                                 

Gene name
Map3k7, B430101B05, C87327, Tak1
Definition
(RefSeq) mitogen-activated protein kinase kinase kinase 7
  KO
K04427  mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04064  NF-kappa B signaling pathway
mmu04140  Autophagy - animal
mmu04152  AMPK signaling pathway
mmu04310  Wnt signaling pathway
mmu04380  Osteoclast differentiation
mmu04520  Adherens junction
mmu04620  Toll-like receptor signaling pathway
mmu04621  NOD-like receptor signaling pathway
mmu04622  RIG-I-like receptor signaling pathway
mmu04657  IL-17 signaling pathway
mmu04660  T cell receptor signaling pathway
mmu04668  TNF signaling pathway
mmu05135  Yersinia infection
mmu05140  Leishmaniasis
mmu05145  Toxoplasmosis
mmu05161  Hepatitis B
mmu05162  Measles
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    26409 (Map3k7)
   04310 Wnt signaling pathway
    26409 (Map3k7)
   04064 NF-kappa B signaling pathway
    26409 (Map3k7)
   04668 TNF signaling pathway
    26409 (Map3k7)
   04152 AMPK signaling pathway
    26409 (Map3k7)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    26409 (Map3k7)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    26409 (Map3k7)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    26409 (Map3k7)
   04621 NOD-like receptor signaling pathway
    26409 (Map3k7)
   04622 RIG-I-like receptor signaling pathway
    26409 (Map3k7)
   04660 T cell receptor signaling pathway
    26409 (Map3k7)
   04657 IL-17 signaling pathway
    26409 (Map3k7)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    26409 (Map3k7)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    26409 (Map3k7)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    26409 (Map3k7)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    26409 (Map3k7)
   05162 Measles
    26409 (Map3k7)
   05161 Hepatitis B
    26409 (Map3k7)
   05168 Herpes simplex virus 1 infection
    26409 (Map3k7)
   05169 Epstein-Barr virus infection
    26409 (Map3k7)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    26409 (Map3k7)
   05140 Leishmaniasis
    26409 (Map3k7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    26409 (Map3k7)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     26409 (Map3k7)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: TKL group
  MLK family
   26409 (Map3k7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Pkinase APH
Motif
Other DBs
NCBI-GeneID: 26409
NCBI-ProteinID: NP_766276
MGI: 1346877
Ensembl: ENSMUSG00000028284
Vega: OTTMUSG00000004905
UniProt: Q62073 Q543B5
LinkDB All DBs
Position
4; 4 A5
AA seq 579 aa AA seqDB search
MSTASAASSSSSSSASEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIVATAGNGQPRRRSIQDLTVTG
TEPGQVSSRSSSPSVRMITTSGPTSEKPARSHPWTPDDSTDTNGSDNSIPMAYLTLDHQL
QPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRL
VQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
NT seq 1740 nt NT seq  +upstreamnt  +downstreamnt
atgtcgacagcctccgccgcctcgtcctcctcctcgtcttctgccagtgagatgatcgaa
gcgccgtcgcaggtcctgaacttcgaagagatcgactacaaggagatcgaggtggaagag
gttgtcggaagaggagcttttggagtagtttgcaaagctaagtggagagcaaaagatgtc
gctattaaacagatagaaagtgagtctgagaggaaggctttcattgtggagctccggcag
ttgtcacgtgtgaaccatcctaacattgtcaagttgtatggagcctgcctgaatccagta
tgtcttgtgatggaatatgcagaggggggctcattgtataatgtgctgcatggtgctgaa
ccattgccttactacactgctgctcatgccatgagctggtgtttacagtgttcccaagga
gtggcttacctgcacagcatgcagcccaaagcgctgattcacagggacctcaagcctcca
aacttgctgctggttgcaggagggacagttctaaaaatctgcgattttggtacagcttgt
gacatccaaacacacatgaccaataataaagggagtgctgcttggatggcgcctgaagta
tttgaaggtagcaattacagtgaaaagtgtgatgtcttcagctggggtattatcctctgg
gaagtgataacacgccggaaacccttcgatgagatcggtggcccagctttcagaatcatg
tgggctgttcataatggcactcgaccaccactgatcaaaaatttacctaagcccattgag
agcttgatgacacgctgttggtctaaggacccatctcagcgcccttcaatggaggaaatt
gtgaaaataatgactcacttgatgcggtacttcccaggagcggatgagccgttacagtat
ccttgtcagtactctgatgaagggcagagcaactcagccaccagcacaggctcattcatg
gacattgcttctacaaataccagtaataaaagtgacacaaatatggaacaggttcctgcc
acaaacgacactattaaacgcttggagtcaaaacttttgaaaaaccaggcaaagcaacag
agtgaatctggacgcctgagcttgggagcctctcgtgggagcagtgtggagagcttgccc
cccacttccgagggcaagaggatgagtgctgacatgtctgaaatagaagccaggatcgtg
gcgactgcaggtaacgggcaaccaaggcgtagatccatccaagacttgactgttactggg
acagaacctggtcaggtgagcagccggtcatccagccctagtgtcagaatgatcactacc
tcaggaccaacctcagagaagccagctcgcagtcacccgtggacccctgatgattccaca
gataccaatggctcagataactccatcccaatggcgtatcttacactggatcaccagcta
cagcctctagcgccgtgcccaaactccaaagaatccatggcagtgttcgaacaacattgt
aaaatggcacaggagtatatgaaagttcaaaccgaaatcgcattgttactacagagaaag
caagaactagttgcagaattggaccaggatgaaaaggaccagcaaaatacatctcgtctg
gtacaggaacataaaaagcttttagatgaaaacaaaagcctttctacttattaccagcaa
tgcaaaaaacaactagaggtcatcagaagccaacagcagaaacgacaaggcacttcatga

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