KEGG   Mus musculus (mouse): 78390Help
Entry
78390             CDS       T01002                                 

Gene name
Pla2g4d, 2610311B01Rik, Pla2delta, cPLA2delta
Definition
(RefSeq) phospholipase A2, group IVD
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00564  Glycerophospholipid metabolism
mmu00565  Ether lipid metabolism
mmu00590  Arachidonic acid metabolism
mmu00591  Linoleic acid metabolism
mmu00592  alpha-Linolenic acid metabolism
mmu01100  Metabolic pathways
mmu04010  MAPK signaling pathway
mmu04014  Ras signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04217  Necroptosis
mmu04270  Vascular smooth muscle contraction
mmu04370  VEGF signaling pathway
mmu04611  Platelet activation
mmu04664  Fc epsilon RI signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
mmu04724  Glutamatergic synapse
mmu04726  Serotonergic synapse
mmu04730  Long-term depression
mmu04750  Inflammatory mediator regulation of TRP channels
mmu04912  GnRH signaling pathway
mmu04913  Ovarian steroidogenesis
mmu04921  Oxytocin signaling pathway
mmu05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    78390 (Pla2g4d)
   00565 Ether lipid metabolism
    78390 (Pla2g4d)
   00590 Arachidonic acid metabolism
    78390 (Pla2g4d)
   00591 Linoleic acid metabolism
    78390 (Pla2g4d)
   00592 alpha-Linolenic acid metabolism
    78390 (Pla2g4d)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    78390 (Pla2g4d)
   04010 MAPK signaling pathway
    78390 (Pla2g4d)
   04370 VEGF signaling pathway
    78390 (Pla2g4d)
   04072 Phospholipase D signaling pathway
    78390 (Pla2g4d)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    78390 (Pla2g4d)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    78390 (Pla2g4d)
   04664 Fc epsilon RI signaling pathway
    78390 (Pla2g4d)
   04666 Fc gamma R-mediated phagocytosis
    78390 (Pla2g4d)
  09152 Endocrine system
   04912 GnRH signaling pathway
    78390 (Pla2g4d)
   04913 Ovarian steroidogenesis
    78390 (Pla2g4d)
   04921 Oxytocin signaling pathway
    78390 (Pla2g4d)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    78390 (Pla2g4d)
  09156 Nervous system
   04724 Glutamatergic synapse
    78390 (Pla2g4d)
   04726 Serotonergic synapse
    78390 (Pla2g4d)
   04730 Long-term depression
    78390 (Pla2g4d)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    78390 (Pla2g4d)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    78390 (Pla2g4d)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     78390 (Pla2g4d)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B cPLA2_C2 C2
Motif
Other DBs
NCBI-GeneID: 78390
NCBI-ProteinID: NP_001019308
MGI: 1925640
Ensembl: ENSMUSG00000070719
Vega: OTTMUSG00000015285
UniProt: Q50L43
LinkDB All DBs
Position
2; 2 E5
AA seq 825 aa AA seqDB search
MWSGDRRVGMESLSPERLHGHPYQEEASVFCRLTVKILEARSLPRADLLSQADPYVTVQL
PTASGMKFKTQTVTNSSHPVWNETFSFLIQSQVKNILELTIYDEDVITKDDICFKVSYDV
SEILPGQLLQKTFSLNPQGPEELDVELLMERTWDPPENLITNNVLVARELSHLDVSLDRA
GNTAMAAGQDKLELELMLKGSYEDTQTFFPDTAFTFSFHYMRGQDTELNGYLRGPRNSGW
NSDTSVTPFNVPLMSLAAGKEMTIDIPAMKAPEGKLQLKTDCCPKELSVRLSYGLCPEEQ
AFLSRRKKVVAAALKQALQLDEDLNEDEVPVVGINAEGGGMRAMISLYGHLLALQKLGLL
DCVTYFSGISGSTWTMAHLYRDPEWSQRDLEGPISHAREHVAKTLLKEFLPEHLASYRQT
LKLREEQGYTVTVADLWGLVLESKLHGQVTDQKLSGQRAALERGQNPLPLYLSLNVKENH
LETLHFKEWVEFSPYEVGFLKYGGFVPSELFGSEFFMGRLMKRLPESQICFLEGIWSNLF
SVNLMDIWYDITYGKDSNNFPVDVRNSEKEFSGSAGTSSGVEAPWLESGTALAQALKGFL
TGRPFHQRSANFLHGLQLHRDYCNQRHFSTWADCNLDDTPNQLTPQDPQLCLIDAGCFMN
SSCPSLFRPGRQVDLIISFNYNQSLPFKGLQQSEKYSRARGLPFPRVEPSPEDHSQPQEC
YLFSDPTCPEAPVVLHFPLVNDSFRDHSAPGVRRSPDELKAGQVNLTGAASPYFMYNMTY
KNEDFDRLLQLSDYNVQNNQGTILQALRTVLKRRASETRPLGVKT
NT seq 2478 nt NT seq  +upstreamnt  +downstreamnt
atgtggagtggagatagaagagtaggcatggagagcctgtcacccgagagactacatggc
catccttaccaggaggaggcctctgtcttctgccggctcactgtgaaaatcctggaggct
cggagtctgcccagggctgacctgttgagtcaggcagatccctatgtgactgtgcagctg
ccaacagcttctggaatgaaattcaagacccaaacagtcactaactccagtcatcctgtg
tggaacgagaccttcagtttcctcatccagagtcaggtcaagaacattctagaactaact
atctatgacgaagacgtaattacgaaagatgacatctgcttcaaggtttcttatgatgtc
tcagaaatccttcctggacagctgctccagaaaaccttcagcctgaatcctcagggacca
gaagagttagatgtggagctcctaatggaaagaacgtgggaccctccagaaaacctcatc
accaacaatgttcttgtggcccgagaactgtcacacctggatgtctccctggacagagcc
gggaacaccgccatggcagcaggccaggacaaactagagctggagcttatgctgaagggg
tcatatgaggacacacagacatttttcccggacacagcttttaccttcagcttccactac
atgaggggccaagacacagaactgaatgggtacctgaggggccccagaaacagtggctgg
aactcagatacctcggtgacacctttcaatgtacccctgatgtcgttggccgcagggaag
gagatgaccatagacattcctgctatgaaggctccagaagggaagctgcagcttaagaca
gactgttgccccaaagagctgtctgtgaggctgagctatgggctctgtcccgaggagcag
gccttcctaagcaggaggaagaaggtggtggctgccgccctgaagcaggctctgcaactg
gatgaagacttgaacgaagatgaggtccctgttgtgggcatcaatgctgagggaggaggt
atgcgggctatgatctcactctacggccacctactggcgcttcagaagttgggcctcctg
gactgtgtgacctacttcagtggcatctcaggctctacatggacaatggcccacctgtac
agggacccagagtggtcacagagggacctcgaaggacccatcagtcatgctagggagcat
gtggctaaaaccctgctgaaggaattcctccccgaacacttggcaagctaccgccagaca
ctgaagcttcgggaagagcagggctacaccgtcacggtagcagacctgtggggcctggtg
ctggagtccaagctgcatgggcaggtgacagatcagaagctgtcaggacagagagctgca
ctggagaggggtcagaaccctttgcctctctacttgagcctcaatgtcaaagagaaccat
ctggaaaccctccacttcaaggaatgggtagagttctctccctatgaagttgggtttctg
aaatatggaggctttgtcccttctgagctcttcggctctgagttcttcatgggacggctg
atgaagagacttcccgagtcccagatttgctttctggaaggtatctggagcaaccttttc
tctgtgaacctgatggatatctggtatgacatcacctatgggaaagactcaaacaatttc
cctgtggatgtccggaactcagagaaggagttctcaggctcagcaggaacctcctctggt
gtggaggccccatggctggagtctggaacagctctggcccaggcacttaagggctttctg
actggcaggccattccaccagcgtagcgccaacttcctccatggcctccagctgcaccgg
gactactgtaaccagagacacttctccacctgggcggattgcaacctagatgacaccccg
aatcagctgaccccacaggaccctcagctctgcctaattgatgctggctgcttcatgaac
agcagctgtccctccctgttccgcccaggtcgccaagtggacctcataatctccttcaat
tacaaccaatcccttccctttaaggggctgcagcaatctgagaaatacagcagagctcgg
ggcctgcccttcccccgtgtggagcccagcccagaggaccacagccagccccaggaatgt
tacctcttctcagaccccacctgcccggaagcacccgttgtgctgcacttcccgctggtc
aatgactccttcagggatcactcagcccctggtgtcaggcgcagccctgatgagctcaag
gctgggcaggtgaatctcacaggggctgcctccccctacttcatgtacaacatgacctac
aagaacgaagatttcgaccggttgcttcagctctctgactacaatgttcagaacaaccag
ggcactatcctgcaggccctgaggacagttctgaaacggagggcttcagagaccaggcca
ttgggagtgaagacgtga

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