Miniopterus natalensis: 107524933 Help Entry 107524933         CDS       T05883                                  Gene name NOS3 Definition (RefSeq) nitric oxide synthase, endothelial   KO K13242   nitric-oxide synthase, endothelial [EC:1.14.13.39] Organism mna  Miniopterus natalensis Pathway mna00220   Arginine biosynthesis mna00330   Arginine and proline metabolism mna01100   Metabolic pathways mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04066   HIF-1 signaling pathway mna04071   Sphingolipid signaling pathway mna04151   PI3K-Akt signaling pathway mna04370   VEGF signaling pathway mna04371   Apelin signaling pathway mna04611   Platelet activation mna04915   Estrogen signaling pathway mna04921   Oxytocin signaling pathway mna04926   Relaxin signaling pathway mna04931   Insulin resistance mna04933   AGE-RAGE signaling pathway in diabetic complications mna05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     107524933 (NOS3)    00330 Arginine and proline metabolism     107524933 (NOS3)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     107524933 (NOS3)    04371 Apelin signaling pathway     107524933 (NOS3)    04066 HIF-1 signaling pathway     107524933 (NOS3)    04020 Calcium signaling pathway     107524933 (NOS3)    04071 Sphingolipid signaling pathway     107524933 (NOS3)    04022 cGMP-PKG signaling pathway     107524933 (NOS3)    04151 PI3K-Akt signaling pathway     107524933 (NOS3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107524933 (NOS3)   09152 Endocrine system    04915 Estrogen signaling pathway     107524933 (NOS3)    04921 Oxytocin signaling pathway     107524933 (NOS3)    04926 Relaxin signaling pathway     107524933 (NOS3)  09160 Human Diseases   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     107524933 (NOS3)   09167 Endocrine and metabolic disease    04931 Insulin resistance     107524933 (NOS3)    04933 AGE-RAGE signaling pathway in diabetic complications     107524933 (NOS3) Enzymes [BR:mna01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      107524933 (NOS3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 HTH_15 Motif Other DBs NCBI-GeneID:  107524933 NCBI-ProteinID:  XP_016052486 LinkDB All DBs Position Unknown AA seq 1202 aa AA seqDB search MGNLKSVGQEPGPPCGLGLGLGLSLCGKQGPASPTPASEPSRTPAPTPLPAPDPSPPLTQ PPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPCQGPPPAE QLLSQAQDFINQYYSSIKRAGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA PRCVGRIQWGKLQVFDARDCSSAQEMFTYICSHIKYATNRGNLRSAITVFPQRAPGRGDF RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPE LFTVPPELVLEVPLEHPTLEWFASLGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTE IGMRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHH AATSSFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQXDPWK GSAAKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRL FRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAGALMEMSGPYNSSP RPEQHKSYKMRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFC AFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAAR DIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKVFQATVLSVENLQSSKSTRATILV RLDTGGLEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGGPP PGWVRDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEESSEQQELESLSQDPRRYE EWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLA YRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPF RGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSREP NSPKTYVQDVLRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMELDE AGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHMRSAVPWAFDPPGADTP GP NT seq 3609 nt NT seq  +upstreamnt  +downstreamnt atgggcaacttgaagagcgtgggccaggagcccgggccaccctgcggcctggggctgggg ctgggcctcagcctgtgcggcaagcaaggcccggcctccccaacaccagcgtctgagccc agccggacaccagcacccacacccctgcctgcaccagaccccagccccccgctgacccag cccccggaggggcccaagttccctcgtgtgaagaactgggaggtggggagcattacctac gacaccctcagtgcccaggcacagcaggatgggccctgcaccccacgacgctgcctgggc tccctagtatttccaaggaaactgcagagccggccctgccagggccctccacccgccgag cagctgttgagccaggcccaggacttcataaaccagtactacagttccatcaagagggct ggctcccaagcccacgagcagcggctccaggaggtggaagccgaggtggcagccacgggc acctaccagcttcgggagagcgagctggtgttcggggccaagcaggcctggcgcaacgcc ccacgctgcgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggattgc agctctgcacaggagatgttcacctacatctgtagccacatcaagtacgccaccaaccgg ggcaacctgcgctccgccatcacagtgttcccccagcgcgccccgggccgcggggacttc cgaatctggaacagccagctggtgcgctacgcgggctacaggcagcaggatggctccgtg aggggggacccagccaacgtggagatcacggagctctgcatccagcacggctggacccca ggcaacggccgcttcgacgtcctgcccctgctgctccaggcccccgacgaacctccggaa ctcttcactgtgccccccgagctagtcctcgaggtgcctctggagcaccccacgctggag tggttcgcctccctgggcctgcgctggtacgcgctcccggccgtgtccaacatgctgctg gaaatcgggggcctggagttccccgcggcccctttcagcggctggtacatgagcacggag atcggcatgcggaacctgtgtgacccgcaccgctacaacatcctggaggatgtggctgtc tgcatggacctggatacccggacaacctcgtccctgtggaaggacaaagcagcagtggag atcaacctggccgtgctgcacagttaccagctggccaaggtgaccatcgtggaccaccac gcagccacctcctccttcatgaagcacctagagaacgagcagaaggccaggggcggctgt cctgccgactgggcctggatcgtgccccccatctcgggcagcctcacccctgtcttccac caggagatggtcaactacttcctgtcccctgccttccgctaccagncagacccctggaag ggcagtgcagccaagggcgctggcatcaccaggaagaagacctttaaggaagtggccaat gcagtgaagatctctgcctcgcttatgggcaccgtgatggccaagcgtgtgaaggcgacg atcctgtacggctccgagaccggccgggcccagagctacgcgcagcagctggggaggctc ttccggaaggctttcgacccccgggtcctgtgcatggacgagtatgacgtggtgtccctt gagcatgagacgctggtgctggtggtgaccagcacgtttgggaatggggatcccccggag aatggagagagtttcgcaggcgccctgatggagatgtccggaccctacaacagctccccg aggccggaacagcacaagagttacaaaatgcgcttcaacagtgtttcctgctcggacccg ctggtgtcctcctggcggcggaagaggaaggagtccagcaacacagacagtgcgggggca ctgggcaccctcaggttctgcgtgtttgggctgggctcccgggcctacccccacttctgc gcctttgcccgcgcggtggacacacggctggaagagctgggcggggagcggctcctgcag ctgggccagggcgacgagctgtgcggccaggaggaggccttccgtggctgggcgcaggcc gccttccaggcctcctgtgagaccttctgcgtgggggaggatgccaaggccgccgcccgg gacatattcagccccaaaaggagctggaagcgccagaggtaccggctgagcacccaggcc gagggcctccagctgctgccaggcctgatccacgtgcacaggagaaaggtgttccaggcc actgtcctctccgtggagaacctgcagagcagcaagtccacccgggccactatcctggtg cgcctggacaccggaggcctggaggggctccagtaccagccaggggaccacataggcgtc tgcccgcccaatcggccgggcctcgtggaggcgctgctgagccgtgtggaggacccgccg ccacctggcgagcccgtggcagtggagcagctggagaagggcagccctggtggccctccc ccaggctgggtgcgggacccccggctgcccccctgcacactgcgccaggctctcaccttc ttcctggacatcacgtccccacccagccctcgactcctccgactgctcagcaccctggct gaagagtccagcgaacagcaggagcttgagagccttagccaggacccccggcgctacgag gagtggaagtggttccgctgccccacgctgctggaggtgctggagcagtttccgtcggtc gctctgcccgcccccctgctcctcactcagctgcccctgctccagccccggtactactca gtcagctcagcacccagcacccacccaggggagatccacctcacagtggccgtgctggca tacaggacccaggatgggctgggtcccctgcactacggagtctgctctacatggctgagc caactcaaggctggagaccctgtgccctgcttcatcaggggggctccctccttccggcta ccacctgaccccagcttgccctgtatcctggtgggcccgggcactggcatcgcccccttc agaggattctggcaggagcggctgcatgacattgagagcaaagggctgcagcccgcgccc atgaccttggtattcggctgccgatgctcccagctggaccacctctaccgcgacgaggtg caggacgcccagcagcgcggcgtgtttggccgagtcctcactgccttctcccgagaaccc aacagccctaagacctacgtgcaggacgtcctgcggacggagctggccgccgaggtgcac cgcgtgctgtgcctcgaacggggccacatgtttgtctgcggcgatgtcaccatggcaacc agcgtcctgcagacggtgcagcgcatcctggcgacagagggcgacatggagctggacgag gccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacattttcggg ctcacgctgcgcacccaggaggtgacaagccgcatccgcacccagagcttctccttgcag gagcggcatatgcgcagcgcagtgccctgggctttcgacccgccgggcgcagacaccccc gggccctga

Miniopterus natalensis: 107528483 Help Entry 107528483         CDS       T05883                                  Gene name NOS1 Definition (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism mna  Miniopterus natalensis Pathway mna00220   Arginine biosynthesis mna00330   Arginine and proline metabolism mna01100   Metabolic pathways mna04020   Calcium signaling pathway mna04145   Phagosome mna04371   Apelin signaling pathway mna04713   Circadian entrainment mna04730   Long-term depression mna04926   Relaxin signaling pathway mna04970   Salivary secretion mna05010   Alzheimer disease mna05014   Amyotrophic lateral sclerosis mna05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     107528483 (NOS1)    00330 Arginine and proline metabolism     107528483 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     107528483 (NOS1)    04020 Calcium signaling pathway     107528483 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     107528483 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     107528483 (NOS1)   09154 Digestive system    04970 Salivary secretion     107528483 (NOS1)   09156 Nervous system    04730 Long-term depression     107528483 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     107528483 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     107528483 (NOS1)    05014 Amyotrophic lateral sclerosis     107528483 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     107528483 (NOS1) Enzymes [BR:mna01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      107528483 (NOS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Flavodoxin_5 Motif Other DBs NCBI-GeneID:  107528483 NCBI-ProteinID:  XP_016057052 LinkDB All DBs Position Unknown AA seq 1434 aa AA seqDB search MENHMFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTRPLGPPTTAVDLSHQSSACKEQALAVDGATGPGNGPQHGLDNGPEAGSLAHANGLAP RPPGQAPAKKNPGIALQGSGEHNELLKEIQPVLNLLTTGDKGINGGAPAKAETKDVEVQV DRDVDSKSHKPLPLGVENDHVVNDLWGTGSVPVVLNNPYSEKEQPPASGRQSPTKNGSPS KCPRFLKVKNWETDVVLTDTLHLKSTLETGCSEHICMGSIMHTSQQIRRPEDVRTKEQLF PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC VGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRIDSKHDFRVW NSQLIRYAGYKQPDGSILGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ IPPELVLEVPIRHPKFEWFRDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV WKGSNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRQPNSVH EERKSYKVRFNSVSSYSDSRKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF GHAVDTLLEELGGERILKMGEGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN SLISNDRSWKRNKFRLTYVAEAPELAQGLSSVHKKRVSAARLLSRQNLQSPKSSRSTIFV RLHTNGNQELQYQPGDHLGVFPGNHEDLVNALIERLEDSPPVNQLVKVELLEERNTALGV ISNWTDEHRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEY EEWKWGKNPTIVEVLEEFRSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIV SYSTRDGDGPVHHGVCSSWLNRIQAAEVVPCFVRGAPSFHLPQNPQVPCILVGPGTGIAP FRSFWQQRQFDIQHRGMSPCPMILVFGCRQSKIDHIYREETLQARNTGVFRELYTAYSRE PDKPKKYVQDILQEKLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMAQQGKLSVE DAGVFISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS NT seq 4305 nt NT seq  +upstreamnt  +downstreamnt atggagaatcacatgttcagtgttcagcagatccaacccaacgtgatttctgtccgcctc ttcaagcgcaaagtggggggcctggggttcctggtgaaggagcgagtgagcaagcccccc gtgatcatctccgacctgattcgagggggcgccgcagagcagagtggcctcatccaggcc ggggacatcatcctcgcggtcaatggccagcccctggtggacctgagttatgacagcgcc ctggaggtgctcaggggcattgcctccgagacccacgtggtcctcattctgaggggcccc gagggcttcaccacgcacctggagaccaccttcactggggacgggacccccaagaccatc cgggtgacacggcccctgggtccccccaccacagccgtcgatctgtcacaccagtcgtca gcctgcaaagagcaggcgctggcagtggacggggccaccggtcccggcaatgggccacag catggcctcgacaatggaccggaagctggctcgctggctcacgctaatggcctggccccc aggcccccgggccaggcccccgccaagaagaatcctgggattgcccttcagggcagcggg gagcacaatgaactcctcaaagagatccagcctgtcctgaaccttctcaccactggtgac aaaggcatcaatggaggggcaccggccaaggcggagacaaaggacgtggaagtccaggtg gacagagacgtggacagcaagtcacacaagcctctgccccttggcgtggagaatgaccac gtcgtcaatgacctgtgggggacgggcagtgtgcccgtggtcctcaacaacccgtattcc gagaaggagcagccccctgcctcgggacgacagtcccccacgaagaatggcagcccctcc aagtgcccccgcttcctcaaggtcaagaactgggagacggacgtggttctcacggacacc ctccaccttaagagtaccctggaaacgggatgcagtgagcacatctgcatggggtccatc atgcacacttcccagcaaatccggaggcctgaagatgtccgcacgaaagagcagctcttc cctcttgccaaagagttcattgatcagtactactcgtcaattaaaagatttggctccaaa gcccacatggagaggctggaagaggtgaacaaagagattgaaaccaccagcacctaccag ctcaaagacactgagctcatctacggggccaagcacgcctggaggaatgcctcccgctgc gtcggcaggatccagtggtccaagctgcaggtgttcgatgcccgcgactgcaccacggcc cacgggatgttcaactacatttgcaaccacatcaagtatgccaccaacaaagggaacctc aggtctgccatcaccatatttccgcagaggatcgacagcaagcacgatttccgagtctgg aactcccagctcatccgctatgccggctacaagcagcccgacggctccatcctgggagac ccagccaatgtgcagttcacagagatctgcatacagcaaggctggaaacccccgagaggt cgcttcgatgtcctgccgctcctgctccaggccaacggcaatgaccccgagctcttccag attcctccagagctggtgttagaagtgcccatcaggcaccccaagtttgaatggttcagg gacctggggctgaagtggtacggcctccccgctgtgtccaatatgcttctggagattggt ggcctggagttcagcgcctgtcccttcagcggctggtacatgggcacggagattggcgtc cgtgactactgtgacaactctcggtacaacatcctggaggaagtggccaagaagatgaac ttggacatgaggaagacgtcttccctgtggaaggaccaggcgctggtggagatcaacatc gcggtcctctacagcttccagagtgacaaagtgaccatcgtcgaccaccactcggccacc gagtccttcattaaacacatggaaaatgaataccgctgccgggggggctgcccggccgac tgggtgtggatcgtgccccccatgtctggcagcatcaccccggtcttccaccaggagatg ctcaactaccggctcaccccgtccttcgaataccagcctgacccttggaacacccatgtc tggaaaggcagcaacgggacccccacaaagcgacgagccatcggcttcaagaagctggca gaagccgtcaagttctcggccaagctgatggggcaggcaatggccaagagggtcaaggcg accatcctttatgccacagagacgggcaaatcacaggcctatgccaaaaccttgtgtgag atcttcaagcacgcctttgatgccaaggtgatgtccatggaagaatacgacattgtgcac ctggaacatgagactctggtcctggtggtcaccagcacctttggcaacggagacccccct gagaacggagagaaattcggctgcgctctgatggaaatgaggcaacccaactctgtgcac gaggaaaggaagagctacaaggtcaggttcaatagtgtttcctcctattccgactcccgc aaatcatcaggcgacgggccggacctcagagacaacttcgagagcgctggccccctggca aatgtgaggttctcggtgtttggccttggctctcgggcttacccccacttctgcgccttt ggacatgccgtggatacgctcctggaagagttgggaggagagaggatcctgaagatgggg gagggggatgagctctgtgggcaggaggaggctttcaggacctgggccaagaaggtcttc aaggcagcctgtgatgtgttctgcgtgggagatgacgtcaacatcgagaaggcgaacaac tccctcatcagcaacgaccgcagctggaagaggaacaagttccgcctcacctatgtggcc gaagctccggagctcgcccaaggtctgtccagtgtccacaaaaagcgggtctcagccgct cggctgctcagccgtcaaaaccttcagagccctaagtccagccgatcaaccatcttcgtg cgtctccacaccaacgggaaccaggagctgcagtaccagcctggggaccacctgggcgtc ttccccggcaaccacgaggacctcgtgaatgcccttatcgagcggctggaggactcaccc cctgtcaaccagctggtgaaagtggagctgctggaagagcggaacacggccttgggagtt atcagcaactggacggatgagcaccgcctgccgccctgcaccatcttccaggccttcaag tactacctggacatcaccactccgcccacgccgctgcagctgcagcagtttgcctccctg gccaccagcgagaaagagaagcagcgtctgctggtcctcagcaagggattgcaggagtac gaggaatggaaatggggcaagaatcccaccattgtggaggtgctggaggagttccggtcc atccagatgcctgccaccctgctcctgacccagctgtcgctcctgcagcctcgttactat tccatcagctcctccccggacatgtaccccgatgaggtgcacctcaccgtggctatcgtc tcctactccacccgagatggagacggaccagttcaccacggggtgtgctcctcctggctc aaccggatacaggctgccgaggtggtcccctgtttcgtgagaggggctcccagcttccac cttccccaaaatccccaagtgccctgcatcctggttggcccgggcaccggcatcgcccct ttccgaagcttctggcagcagcggcaatttgatatccaacacagaggcatgagcccctgc cccatgatcctggtcttcgggtgccggcagtccaagatagaccacatctacagggaggag accctgcaggccaggaacacgggcgtcttcagagagctgtacacggcctactcccgggag ccagacaaaccaaagaagtacgtgcaggacatcctgcaagagaagctggcggaatccgtg taccgagccctgaaggagcaagggggccacatttacgtctgtggggacgtcaccatggcc gccgatgtcctcaaagccatccagcgcatcatggcccagcaggggaaactctccgtggag gacgccggcgtgttcatcagccggctgagggatgacaaccgctaccatgaggatattttc ggggtcaccctgcgaacgtatgaagtgaccaaccgccttagatctgaatccattgccttc atcgaagagagcaaaaaagacactgatgaggtttttagctcctaa

Miniopterus natalensis: 107533063 Help Entry 107533063         CDS       T05883                                  Gene name NOS2 Definition (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism mna  Miniopterus natalensis Pathway mna00220   Arginine biosynthesis mna00330   Arginine and proline metabolism mna01100   Metabolic pathways mna04020   Calcium signaling pathway mna04066   HIF-1 signaling pathway mna04146   Peroxisome mna04371   Apelin signaling pathway mna04926   Relaxin signaling pathway mna05010   Alzheimer disease mna05014   Amyotrophic lateral sclerosis mna05022   Pathways of neurodegeneration - multiple diseases mna05133   Pertussis mna05140   Leishmaniasis mna05142   Chagas disease mna05145   Toxoplasmosis mna05146   Amoebiasis mna05152   Tuberculosis mna05200   Pathways in cancer mna05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     107533063 (NOS2)    00330 Arginine and proline metabolism     107533063 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     107533063 (NOS2)    04066 HIF-1 signaling pathway     107533063 (NOS2)    04020 Calcium signaling pathway     107533063 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     107533063 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     107533063 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107533063 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     107533063 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     107533063 (NOS2)    05014 Amyotrophic lateral sclerosis     107533063 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     107533063 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     107533063 (NOS2)    05152 Tuberculosis     107533063 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     107533063 (NOS2)    05145 Toxoplasmosis     107533063 (NOS2)    05140 Leishmaniasis     107533063 (NOS2)    05142 Chagas disease     107533063 (NOS2) Enzymes [BR:mna01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      107533063 (NOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  107533063 NCBI-ProteinID:  XP_016063124 LinkDB All DBs Position Unknown AA seq 1139 aa AA seqDB search MKEPDINNNTDKTMRVPYSAVTQDDPKCHSLGKHRNESPQPFTGTGKKSPESLVKLDAPP SACPQHVRIKNWGSGMTFQDTLHHKAKGDLACKSKCCLGAIMNSKSLTRGPRDRPTSPDE LLPQAIEFVNQYYSSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIYATKQAWRNAP RCIGRIQWSNLQVFDARSCSTAQEMFEHICRHLRYATNNGNIRSAITVFPQRSDGKHDFR VWNAQLIRYAGYQMPDGTIRGDPACLEFTQLCIDLGWKPKYGRFDVVPLVLQAGGRDPEL FEIPPDLVLEVPMEHPKYEWFRELGLKWYTLPAVSNMLLEVGGLEFPGCPFNGWYMGTEI GVRDFCDAQRYNILEEVGRRMGLETHKLASLWKDQAVIEINVAVLHSFQKQNVTIMDHHS AAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEMLNYVLSPFYYYQVEAWKT HVWQDEKRRPQRRVIRFQVLAKAVLFASMLIRKTMASRVRATILFATETGRSETLARDLG ALFSCAFNPKVLCMDEYRLSSLEEERLLLVVTSTFGNGDSPGNGEKLKKSLFMLKKLTNK FRYAVFGLGSSMYPQFCAFAHDVDQKLSHLGASQLTPTGEGDELSGQEEAFRSWAVQTFK AACEAFDVRGKHCIQIPKLYTTSVTWDPRHYRLVQDSQPLDLNKALSSMHAKNVFTMKLK SRQNLQSPKSSRSTLLVELSSEGSQGLSYLPGEHLGVFPSNQPALVQGILERVVDNPAPH QPVCLETLSETGSYWVRDKRLPPCSLSQALTYFLDITTPPTQLLLRKLAQLASEEAERQR LETLCQPSEYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQLPVLKPRYYSISSSRDCTP TEIHLTVAVLTYHTRDGQGPLHHGVCSTWLSSLEPQDPVPCFVRSASGFQLPENTSHPCI LIGPGTGIAPFRSFWQQRLHDAEHKGLQCGHMTLVFGCRRPDEDHLYREEMLEMARRGVL HAVHTAYSRLPGQPKVYVQDILQQKLATEVLHVLHKEQGHLYVCGDAHMARDVAHTLKQL VAAKLSLSEEQVEDYFFQLKSQKRYHEDIFSAVFPYKVKRDGAAGQPSDPRAPAAHRRS NT seq 3420 nt NT seq  +upstreamnt  +downstreamnt atgaaggaaccagacatcaacaacaatacagacaaaaccatgcgggttccctacagtgca gtgacacaggatgaccccaagtgtcacagccttggcaagcaccggaatgagtccccccag cccttcacggggacaggaaagaagtctccagaatccctggtcaagctggatgcaccccca tcagcctgcccacagcatgtgaggatcaaaaactggggcagtggaatgactttccaagac acacttcaccacaaggccaaaggggacttggcttgcaaatctaagtgttgcttgggagcc atcatgaactccaaaagtttgaccagaggacccagggacaggcctacctctccagatgag cttctacctcaagctatcgaatttgtcaaccagtattacagctccttcaaagaggcaaaa atagaggaacatctggccagggtggaagctgtaacaaaggagatagaaacaacaggaacc taccagctgacgggagatgagctcatctacgccaccaagcaggcctggcgcaatgccccg cgctgcatcgggaggatccagtggtccaacctgcaggtctttgatgcccggagctgttcc actgcccaggaaatgttcgagcacatctgccgacacctgcgatatgccaccaacaatggc aacatcaggtcggccatcaccgtgttcccccagcggagcgatgggaagcatgacttccga gtctggaacgcacagctcatccgctacgccggctaccagatgcctgatggcaccatcaga ggggaccctgcctgcctggagttcacccagctgtgcatcgacctgggctggaaacccaag tatggccgcttcgacgtggtgcctctggtcctgcaggctggtggccgcgaccctgagctc tttgaaatcccgcctgaccttgtgctcgaggtgcctatggaacatcccaagtatgagtgg ttccgggagctggggctgaagtggtacaccctgcctgcagtgtccaacatgctgctcgag gtgggtggcctcgagttcccagggtgccccttcaacggctggtacatgggcacagagatt ggggtccgggacttctgtgatgctcagcgctacaacatcctggaggaagtgggcaggagg atgggcctggaaacgcacaagttggcctcactctggaaggaccaggctgtcattgagatc aatgtcgctgtgctccacagtttccagaagcaaaatgtgaccatcatggatcaccactca gctgcggagtccttcatgaagtacatgcagaatgagtaccggtcccgagggggctgccct gccgactggatctggctggtgcccccgatttctggaagcatcacccccgtgttccaccag gagatgttgaactatgttctgtcccccttctactactaccaggtggaggcctggaaaacc cacgtctggcaggacgagaagaggagaccccagagaagagtgattcgattccaagtcttg gctaaagccgtgctcttcgcctctatgctgatacgcaagaccatggcgtcccgggtcaga gccaccatcctctttgcgacggagacgggaagatcagaaacgctggcccgggacctcggg gccctgttcagctgtgccttcaaccccaaggttctctgcatggacgagtacaggctaagc agcctggaggaggagcggctgctgctggtggtgaccagcacgtttgggaacggagactcc cccggcaatggagagaaactgaagaaatctctcttcatgctgaaaaagctcaccaacaag ttcaggtatgccgtgttcggcctcggctccagcatgtaccctcagttctgcgcctttgct cacgatgtcgaccagaagttgtcccacctgggagcgtctcagctcaccccgacaggggaa ggagatgagctcagtgggcaggaagaggccttccgcagctgggctgtgcaaaccttcaag gcagcctgtgaggcattcgatgtccgaggcaaacactgcattcagatccccaagctctac accaccagtgtgacctgggacccgcgccactacaggctcgtgcaggactctcagcctctg gacctcaacaaagccctcagcagcatgcacgccaagaacgtgttcaccatgaagctcaaa tcgcggcagaatctacagagtccgaaatccagccgctccaccctcctggtggagctctcc agcgagggcagccaaggtctcagctacctgccgggagagcacctgggggttttcccaagc aaccagccggccctggtgcaaggcattttggagcgagtggtggacaaccccgcaccccac caacccgtgtgcctggagaccctcagtgagaccggcagctactgggtcagggacaagcgg ctgcccccctgctcactcagccaggccctcacctacttcctggacatcaccacaccccca acccagctgctgctccgaaagctggcccagctggcttcagaagaggccgagaggcagagg ctagagaccctgtgccagccctcagagtacaacaagtggaagttcaccaacagccccaca ttcctggaggtgctggaggagttcccgtccctgcgggtatctgccagcttcctgctttcc cagctccctgtcctgaaaccccgatactactccatcagctcctccagggactgcaccccc acagagatccacctcaccgtggccgtgctcacctaccacacccgagatggccagggcccc ctgcaccacggtgtctgcagcacatggctcagcagcctggagccccaagacccagtgccc tgttttgtacgaagtgccagcggcttccagctccccgagaacacctcccacccttgcatc ctcattgggcctggcactggcatcgctcccttccgcagtttctggcagcagcgtctccat gatgccgagcacaaagggctccagtgtggccacatgaccctggtgttcgggtgccggcgc ccagacgaggaccacctctatcgggaggagatgctggagatggcccggagaggggtgctg cacgcggtgcacacagcctactcgcgcctgcctggccagcccaaggtctacgttcaagac atccttcagcagaagctggccaccgaggtgctccacgtgctccacaaggagcaaggccac ctctatgtctgtggggatgcgcacatggcccgggatgtggcccacacactgaagcagctg gtggctgccaagctgagcctgagtgaggagcaggtcgaggactatttcttccagcttaag agccagaagcgctaccatgaagatatcttcagtgctgtgtttccctacaaggtgaaaaga gatggggcagcgggacagcctagcgatccccgagctccagcagcccacaggagaagttaa

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