KEGG T05883: 107525695

KEGG Orthology (KO) [BR:mna00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107525695 (MAP2K2)
   04012 ErbB signaling pathway
    107525695 (MAP2K2)
   04014 Ras signaling pathway
    107525695 (MAP2K2)
   04015 Rap1 signaling pathway
    107525695 (MAP2K2)
   04370 VEGF signaling pathway
    107525695 (MAP2K2)
   04371 Apelin signaling pathway
    107525695 (MAP2K2)
   04066 HIF-1 signaling pathway
    107525695 (MAP2K2)
   04068 FoxO signaling pathway
    107525695 (MAP2K2)
   04072 Phospholipase D signaling pathway
    107525695 (MAP2K2)
   04071 Sphingolipid signaling pathway
    107525695 (MAP2K2)
   04024 cAMP signaling pathway
    107525695 (MAP2K2)
   04022 cGMP-PKG signaling pathway
    107525695 (MAP2K2)
   04151 PI3K-Akt signaling pathway
    107525695 (MAP2K2)
   04150 mTOR signaling pathway
    107525695 (MAP2K2)
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    107525695 (MAP2K2)
  09143 Cell growth and death
   04210 Apoptosis
    107525695 (MAP2K2)
   04218 Cellular senescence
    107525695 (MAP2K2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107525695 (MAP2K2)
   04550 Signaling pathways regulating pluripotency of stem cells
    107525695 (MAP2K2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107525695 (MAP2K2)
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    107525695 (MAP2K2)
   04620 Toll-like receptor signaling pathway
    107525695 (MAP2K2)
   04650 Natural killer cell mediated cytotoxicity
    107525695 (MAP2K2)
   04660 T cell receptor signaling pathway
    107525695 (MAP2K2)
   04662 B cell receptor signaling pathway
    107525695 (MAP2K2)
   04664 Fc epsilon RI signaling pathway
    107525695 (MAP2K2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    107525695 (MAP2K2)
   04929 GnRH secretion
    107525695 (MAP2K2)
   04912 GnRH signaling pathway
    107525695 (MAP2K2)
   04915 Estrogen signaling pathway
    107525695 (MAP2K2)
   04917 Prolactin signaling pathway
    107525695 (MAP2K2)
   04921 Oxytocin signaling pathway
    107525695 (MAP2K2)
   04926 Relaxin signaling pathway
    107525695 (MAP2K2)
   04935 Growth hormone synthesis, secretion and action
    107525695 (MAP2K2)
   04919 Thyroid hormone signaling pathway
    107525695 (MAP2K2)
   04916 Melanogenesis
    107525695 (MAP2K2)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    107525695 (MAP2K2)
  09156 Nervous system
   04720 Long-term potentiation
    107525695 (MAP2K2)
   04730 Long-term depression
    107525695 (MAP2K2)
   04722 Neurotrophin signaling pathway
    107525695 (MAP2K2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107525695 (MAP2K2)
   05206 MicroRNAs in cancer
    107525695 (MAP2K2)
   05205 Proteoglycans in cancer
    107525695 (MAP2K2)
   05230 Central carbon metabolism in cancer
    107525695 (MAP2K2)
   05231 Choline metabolism in cancer
    107525695 (MAP2K2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    107525695 (MAP2K2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    107525695 (MAP2K2)
   05225 Hepatocellular carcinoma
    107525695 (MAP2K2)
   05226 Gastric cancer
    107525695 (MAP2K2)
   05214 Glioma
    107525695 (MAP2K2)
   05216 Thyroid cancer
    107525695 (MAP2K2)
   05221 Acute myeloid leukemia
    107525695 (MAP2K2)
   05220 Chronic myeloid leukemia
    107525695 (MAP2K2)
   05218 Melanoma
    107525695 (MAP2K2)
   05211 Renal cell carcinoma
    107525695 (MAP2K2)
   05219 Bladder cancer
    107525695 (MAP2K2)
   05215 Prostate cancer
    107525695 (MAP2K2)
   05213 Endometrial cancer
    107525695 (MAP2K2)
   05224 Breast cancer
    107525695 (MAP2K2)
   05223 Non-small cell lung cancer
    107525695 (MAP2K2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107525695 (MAP2K2)
   05022 Pathways of neurodegeneration - multiple diseases
    107525695 (MAP2K2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107525695 (MAP2K2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    107525695 (MAP2K2)
   05135 Yersinia infection
    107525695 (MAP2K2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    107525695 (MAP2K2)
   05170 Human immunodeficiency virus 1 infection
    107525695 (MAP2K2)
   05161 Hepatitis B
    107525695 (MAP2K2)
   05160 Hepatitis C
    107525695 (MAP2K2)
   05164 Influenza A
    107525695 (MAP2K2)
   05163 Human cytomegalovirus infection
    107525695 (MAP2K2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    107525695 (MAP2K2)
   05165 Human papillomavirus infection
    107525695 (MAP2K2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    107525695 (MAP2K2)
   01522 Endocrine resistance
    107525695 (MAP2K2)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mna01001]
    107525695 (MAP2K2)
Enzymes [BR:mna01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     107525695 (MAP2K2)
Protein kinases [BR:mna01001]
Serine/threonine kinases: STE group
  STE7 family
   107525695 (MAP2K2)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like APH Seadorna_VP7 Kdo

Other DBs

NCBI-GeneID:

107525695

NCBI-ProteinID:

XP_016053423

LinkDB

Position

Unknown

AA seq 444 aa
MKTGILAWDFTRLMPSFISPVPCLLSEWSGALVSERRTPESGTRAIEPELAFQVLRSPNL
SCTLFTNRCPWGLCRANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERIS
ELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGA
FYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVK
PSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLS
LVELSIGRYPIPPPDAKELEAIFGRPMVDGAEGEPHSISPRPRPPGRPISGHGVDSRPAM
AIFELLDYIVNEPPPKLPSGVFTQDFQEFVSKCLIKNPAERADLKMLMNHGFIKRSEVEE
VDFAGWLCKTLRLNQPSTPTRTAV

NT seq 1335 nt +upstreamnt +downstreamnt
atgaagacaggcatcctggcctgggacttcactcgcctgatgcccagttttatctcccca
gttccatgtctcctttcagagtggtcgggagcccttgtgtcagaaaggaggactcctgaa
tctggtaccagggccattgaaccagagctggccttccaggtcctgaggtctcctaaccta
tcttgcacactcttcactaaccgttgcccttggggtctctgcagagcaaacttggtggat
ctccagaagaagctagaggagctagagcttgacgagcagcagaagaagcgtctagaagcc
ttcctcacccagaaggccaaggttggggagctcaaggatgatgacttcgaaaggatctca
gagctgggagccgggaacggcggggtggtcaccaaggtccagcacagaccttcaggcctc
ataatggcaagaaagctgattcacctggagatcaagccggccatccggaaccagatcatc
cgcgagctacaggtgctgcatgagtgtaattccccatacattgtgggcttctacggggcc
ttctacagcgatggggagatcagcatctgcatggagcacatggacggtggctctctggac
caggtgttgaaagaagccaagagaattccagaagaaatcctggggaaggtcagcattgcg
gttctacggggcctggcgtatctccgggaaaagcaccagatcatgcaccgagatgtgaaa
ccatctaacatcctcgtcaactccagaggggagatcaagctgtgcgattttggggtgagc
gggcagctcatcgactccatggccaactccttcgtgggaactcgatcctacatgtctcca
gagcgattgcaaggcactcactactctgtgcagtcggacatctggagcatgggcctgtcc
ctggtggagctgtccatcggaaggtaccccatccccccaccagatgccaaggagctggaa
gctatatttggccggcccatggtcgatggggcagaaggagagcctcacagcatctcacct
cggccaagaccccccggacgccccatcagtggtcacggggtggacagtcgaccagctatg
gctatctttgaactcctggactatattgtgaatgagcctcctcctaagctgcccagtggc
gtcttcacccaggacttccaggagtttgtgagtaaatgcctaattaagaacccagccgaa
cgagcagatctgaagatgctcatgaaccatggcttcatcaaacggtccgaggtggaagaa
gtggattttgctggctggttgtgtaaaacgctgcgtctgaaccagcccagcacgcccacg
cgtaccgctgtgtga

Miniopterus natalensis: 107533801

Entry

107533801 CDS T05883

Gene name

MAP2K1

Definition

(RefSeq) dual specificity mitogen-activated protein kinase kinase 1

K04368

mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]

Organism

mna Miniopterus natalensis

Pathway

mna01521

EGFR tyrosine kinase inhibitor resistance

mna01522

Endocrine resistance

mna04010

MAPK signaling pathway

mna04012

ErbB signaling pathway

mna04014

Ras signaling pathway

mna04015

Rap1 signaling pathway

mna04022

cGMP-PKG signaling pathway

mna04024

cAMP signaling pathway

mna04062

Chemokine signaling pathway

mna04066

HIF-1 signaling pathway

mna04068

FoxO signaling pathway

mna04071

Sphingolipid signaling pathway

mna04072

Phospholipase D signaling pathway

mna04114

Oocyte meiosis

mna04140

Autophagy - animal

mna04150

mTOR signaling pathway

mna04151

PI3K-Akt signaling pathway

mna04210

Apoptosis

mna04218

Cellular senescence

mna04270

Vascular smooth muscle contraction

mna04370

VEGF signaling pathway

mna04371

Apelin signaling pathway

mna04380

Osteoclast differentiation

mna04510

Focal adhesion

mna04540

Gap junction

mna04550

Signaling pathways regulating pluripotency of stem cells

mna04613

Neutrophil extracellular trap formation

mna04620

Toll-like receptor signaling pathway

mna04650

Natural killer cell mediated cytotoxicity

mna04660

T cell receptor signaling pathway

mna04662

B cell receptor signaling pathway

mna04664

Fc epsilon RI signaling pathway

mna04666

Fc gamma R-mediated phagocytosis

mna04668

TNF signaling pathway

mna04720

Long-term potentiation

mna04722

Neurotrophin signaling pathway

mna04725

Cholinergic synapse

mna04726

Serotonergic synapse

mna04730

Long-term depression

mna04810

Regulation of actin cytoskeleton

mna04910

Insulin signaling pathway

mna04912

GnRH signaling pathway

mna04914

Progesterone-mediated oocyte maturation

mna04915

Estrogen signaling pathway

mna04916

Melanogenesis

mna04917

Prolactin signaling pathway

mna04919

Thyroid hormone signaling pathway

mna04921

Oxytocin signaling pathway

mna04926

Relaxin signaling pathway

mna04928

Parathyroid hormone synthesis, secretion and action

mna04929

GnRH secretion

mna04934

Cushing syndrome

mna04935

Growth hormone synthesis, secretion and action

mna05010

Alzheimer disease

mna05022

Pathways of neurodegeneration - multiple diseases

mna05034

Alcoholism

mna05132

Salmonella infection

mna05135

Yersinia infection

mna05160

Hepatitis C

mna05161

Hepatitis B

mna05163

Human cytomegalovirus infection

mna05164

Influenza A

mna05165

Human papillomavirus infection

mna05166

Human T-cell leukemia virus 1 infection

mna05167

Kaposi sarcoma-associated herpesvirus infection

mna05170

Human immunodeficiency virus 1 infection

mna05200

Pathways in cancer

mna05205

Proteoglycans in cancer

mna05206

MicroRNAs in cancer

mna05210

Colorectal cancer

mna05211

Renal cell carcinoma

mna05212

Pancreatic cancer

mna05213

Endometrial cancer

mna05214

Glioma

mna05215

Prostate cancer

mna05216

Thyroid cancer

mna05218

Melanoma

mna05219

Bladder cancer

mna05220

Chronic myeloid leukemia

mna05221

Acute myeloid leukemia

mna05223

Non-small cell lung cancer

mna05224

Breast cancer

mna05225

Hepatocellular carcinoma

mna05226

Gastric cancer

mna05230

Central carbon metabolism in cancer

mna05231

Choline metabolism in cancer

mna05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Brite

KEGG Orthology (KO) [BR:mna00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107533801 (MAP2K1)
   04012 ErbB signaling pathway
    107533801 (MAP2K1)
   04014 Ras signaling pathway
    107533801 (MAP2K1)
   04015 Rap1 signaling pathway
    107533801 (MAP2K1)
   04370 VEGF signaling pathway
    107533801 (MAP2K1)
   04371 Apelin signaling pathway
    107533801 (MAP2K1)
   04668 TNF signaling pathway
    107533801 (MAP2K1)
   04066 HIF-1 signaling pathway
    107533801 (MAP2K1)
   04068 FoxO signaling pathway
    107533801 (MAP2K1)
   04072 Phospholipase D signaling pathway
    107533801 (MAP2K1)
   04071 Sphingolipid signaling pathway
    107533801 (MAP2K1)
   04024 cAMP signaling pathway
    107533801 (MAP2K1)
   04022 cGMP-PKG signaling pathway
    107533801 (MAP2K1)
   04151 PI3K-Akt signaling pathway
    107533801 (MAP2K1)
   04150 mTOR signaling pathway
    107533801 (MAP2K1)
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    107533801 (MAP2K1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    107533801 (MAP2K1)
   04210 Apoptosis
    107533801 (MAP2K1)
   04218 Cellular senescence
    107533801 (MAP2K1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    107533801 (MAP2K1)
   04540 Gap junction
    107533801 (MAP2K1)
   04550 Signaling pathways regulating pluripotency of stem cells
    107533801 (MAP2K1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107533801 (MAP2K1)
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    107533801 (MAP2K1)
   04620 Toll-like receptor signaling pathway
    107533801 (MAP2K1)
   04650 Natural killer cell mediated cytotoxicity
    107533801 (MAP2K1)
   04660 T cell receptor signaling pathway
    107533801 (MAP2K1)
   04662 B cell receptor signaling pathway
    107533801 (MAP2K1)
   04664 Fc epsilon RI signaling pathway
    107533801 (MAP2K1)
   04666 Fc gamma R-mediated phagocytosis
    107533801 (MAP2K1)
   04062 Chemokine signaling pathway
    107533801 (MAP2K1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    107533801 (MAP2K1)
   04929 GnRH secretion
    107533801 (MAP2K1)
   04912 GnRH signaling pathway
    107533801 (MAP2K1)
   04915 Estrogen signaling pathway
    107533801 (MAP2K1)
   04914 Progesterone-mediated oocyte maturation
    107533801 (MAP2K1)
   04917 Prolactin signaling pathway
    107533801 (MAP2K1)
   04921 Oxytocin signaling pathway
    107533801 (MAP2K1)
   04926 Relaxin signaling pathway
    107533801 (MAP2K1)
   04935 Growth hormone synthesis, secretion and action
    107533801 (MAP2K1)
   04919 Thyroid hormone signaling pathway
    107533801 (MAP2K1)
   04928 Parathyroid hormone synthesis, secretion and action
    107533801 (MAP2K1)
   04916 Melanogenesis
    107533801 (MAP2K1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    107533801 (MAP2K1)
  09156 Nervous system
   04725 Cholinergic synapse
    107533801 (MAP2K1)
   04726 Serotonergic synapse
    107533801 (MAP2K1)
   04720 Long-term potentiation
    107533801 (MAP2K1)
   04730 Long-term depression
    107533801 (MAP2K1)
   04722 Neurotrophin signaling pathway
    107533801 (MAP2K1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    107533801 (MAP2K1)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107533801 (MAP2K1)
   05206 MicroRNAs in cancer
    107533801 (MAP2K1)
   05205 Proteoglycans in cancer
    107533801 (MAP2K1)
   05230 Central carbon metabolism in cancer
    107533801 (MAP2K1)
   05231 Choline metabolism in cancer
    107533801 (MAP2K1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    107533801 (MAP2K1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    107533801 (MAP2K1)
   05212 Pancreatic cancer
    107533801 (MAP2K1)
   05225 Hepatocellular carcinoma
    107533801 (MAP2K1)
   05226 Gastric cancer
    107533801 (MAP2K1)
   05214 Glioma
    107533801 (MAP2K1)
   05216 Thyroid cancer
    107533801 (MAP2K1)
   05221 Acute myeloid leukemia
    107533801 (MAP2K1)
   05220 Chronic myeloid leukemia
    107533801 (MAP2K1)
   05218 Melanoma
    107533801 (MAP2K1)
   05211 Renal cell carcinoma
    107533801 (MAP2K1)
   05219 Bladder cancer
    107533801 (MAP2K1)
   05215 Prostate cancer
    107533801 (MAP2K1)
   05213 Endometrial cancer
    107533801 (MAP2K1)
   05224 Breast cancer
    107533801 (MAP2K1)
   05223 Non-small cell lung cancer
    107533801 (MAP2K1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107533801 (MAP2K1)
   05022 Pathways of neurodegeneration - multiple diseases
    107533801 (MAP2K1)
  09165 Substance dependence
   05034 Alcoholism
    107533801 (MAP2K1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107533801 (MAP2K1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    107533801 (MAP2K1)
   05135 Yersinia infection
    107533801 (MAP2K1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    107533801 (MAP2K1)
   05170 Human immunodeficiency virus 1 infection
    107533801 (MAP2K1)
   05161 Hepatitis B
    107533801 (MAP2K1)
   05160 Hepatitis C
    107533801 (MAP2K1)
   05164 Influenza A
    107533801 (MAP2K1)
   05163 Human cytomegalovirus infection
    107533801 (MAP2K1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    107533801 (MAP2K1)
   05165 Human papillomavirus infection
    107533801 (MAP2K1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    107533801 (MAP2K1)
   01522 Endocrine resistance
    107533801 (MAP2K1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mna01001]
    107533801 (MAP2K1)
Enzymes [BR:mna01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     107533801 (MAP2K1)
Protein kinases [BR:mna01001]
Serine/threonine kinases: STE group
  STE7 family
   107533801 (MAP2K1)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like Seadorna_VP7 NAD_binding_6

Other DBs

NCBI-GeneID:

107533801

NCBI-ProteinID:

XP_016064131

LinkDB

Position

Unknown

AA seq 393 aa
MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

NT seq 1182 nt +upstreamnt +downstreamnt
atgcccaagaagaagccgacgcccatccagctgaacccggccccagacggctccgcggtt
aacgggaccagctcggcggagaccaacctggaggctttgcagaagaaactggaagaactg
gagctggatgagcaacagcggaagcgccttgaggcctttcttacccagaagcagaaggtg
ggggaactgaaggatgatgactttgagaagatcagtgagctgggtgctggaaatggtggt
gtggtgttcaaggtctcccacaagccgtccggcctggttatggccagaaagctaattcac
ctggagatcaaacctgcgatccggaaccagatcataagggagctgcaggttctacatgag
tgtaactccccatacatcgtgggcttctatggtgcattctacagcgatggcgagatcagc
atctgcatggaacacatggatgggggttccttggatcaagtcctgaagaaagctggaaga
attcctgaacaaattttaggaaaagttagcattgctgtaataaaaggcctgacatatctg
agggagaagcacaagattatgcatagagatgtcaagccttccaacatcctggtgaactcc
cgtggggagatcaagctctgtgactttggggtcagcgggcagctcattgactccatggcc
aactccttcgtgggcacaaggtcctacatgtcgccagaaagactccaggggactcattac
tcggtgcagtcggacatctggagcatggggctctctctggttgagatggctgttgggagg
tatcccatccctcctccagatgcgaaggagctggagctgatgtttgggtgccaggtggag
ggagatgcggctgagacaccacccaggccaaggacccctgggaggcctcttagctcttat
ggaatggacagccgacctcccatggcaatttttgagttgttggattacatagtcaacgag
cctcctccaaaactgcccagtggagtattcagtctggaatttcaagattttgtgaataaa
tgcttaataaaaaaccctgcagagagagcagatttgaaacaactcatggttcatgctttt
atcaagagatctgatgctgaggaagtggattttgcaggttggctctgctccaccatcggc
cttaaccagcccagcacaccgacccatgcagctggtgtctaa

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