Miniopterus natalensis: 107528232 Help Entry 107528232         CDS       T05883                                  Gene name ADCY6 Definition (RefSeq) adenylate cyclase type 6 isoform X1   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism mna  Miniopterus natalensis Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04742   Taste transduction mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04924   Renin secretion mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04961   Endocrine and other factor-regulated calcium reabsorption mna04962   Vasopressin-regulated water reabsorption mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107528232 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107528232 (ADCY6)    04371 Apelin signaling pathway     107528232 (ADCY6)    04072 Phospholipase D signaling pathway     107528232 (ADCY6)    04024 cAMP signaling pathway     107528232 (ADCY6)    04022 cGMP-PKG signaling pathway     107528232 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107528232 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     107528232 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107528232 (ADCY6)    04062 Chemokine signaling pathway     107528232 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     107528232 (ADCY6)    04923 Regulation of lipolysis in adipocytes     107528232 (ADCY6)    04912 GnRH signaling pathway     107528232 (ADCY6)    04913 Ovarian steroidogenesis     107528232 (ADCY6)    04915 Estrogen signaling pathway     107528232 (ADCY6)    04914 Progesterone-mediated oocyte maturation     107528232 (ADCY6)    04921 Oxytocin signaling pathway     107528232 (ADCY6)    04926 Relaxin signaling pathway     107528232 (ADCY6)    04935 Growth hormone synthesis, secretion and action     107528232 (ADCY6)    04918 Thyroid hormone synthesis     107528232 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     107528232 (ADCY6)    04916 Melanogenesis     107528232 (ADCY6)    04924 Renin secretion     107528232 (ADCY6)    04925 Aldosterone synthesis and secretion     107528232 (ADCY6)    04927 Cortisol synthesis and secretion     107528232 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107528232 (ADCY6)    04270 Vascular smooth muscle contraction     107528232 (ADCY6)   09154 Digestive system    04970 Salivary secretion     107528232 (ADCY6)    04971 Gastric acid secretion     107528232 (ADCY6)    04972 Pancreatic secretion     107528232 (ADCY6)    04976 Bile secretion     107528232 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107528232 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     107528232 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     107528232 (ADCY6)    04727 GABAergic synapse     107528232 (ADCY6)    04725 Cholinergic synapse     107528232 (ADCY6)    04723 Retrograde endocannabinoid signaling     107528232 (ADCY6)   09157 Sensory system    04742 Taste transduction     107528232 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     107528232 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     107528232 (ADCY6)    04213 Longevity regulating pathway - multiple species     107528232 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     107528232 (ADCY6)    04714 Thermogenesis     107528232 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107528232 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     107528232 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107528232 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107528232 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107528232 (ADCY6)    05163 Human cytomegalovirus infection     107528232 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107528232 (ADCY6) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107528232 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Shisa Motif Other DBs NCBI-GeneID:  107528232 NCBI-ProteinID:  XP_016056698 LinkDB All DBs Position Unknown AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRHRTRTSGFCAPRYMSCLQDAQPPSPSPTAPP RCPWQEEAFIRRGGPGKGTELGLRAVALGFEDTETTAAVGVAEVAPDVAPRNRRSCWRRL VQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAYVA LLACAAILFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPHSPSVGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSTLHMILAWQLNRGDAFLWKQLGANMLLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGHGGERNAYL KEQHIETFLILGTSQKRKEEKAMLAKLQRTRANSVEGLMPRWVPDRAFSRTKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS QKVDPRFGAYVACALLVFCFICFIQLLVFPHSMLMFGIYAGIFLLLLITVLTCAVYSCGS LCPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNLTPA DITACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNMLLSLLASSVFLHINSIGKLAMI FVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFSGLDCPAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagtggccttctggtccccaaagtggatgaacggaaaacagcctggggt gaacgcaatgggcagaagcgccctcgtcacaggactcgcaccagtggcttctgtgcgccc cgatatatgagctgcctccaggatgcacagccacccagccccagccctacagctccacct cggtgcccctggcaggaggaggccttcatccggaggggtggcccaggcaagggcactgag ctggggctgcgggcagtggccctgggctttgaggacactgagacaacagcagcggttggg gtggctgaggtggcacccgatgtagcacccaggaacaggcgatcctgctggcgccggctg gtgcaggtgttccagtcgaagcagttccgctcagccaagctggagcgcctgtaccagcgg tacttcttccagatgaaccagagcagcctcacgctgctgatggcggtgctcgtgctgctc acagctgtgctgctggccttccatgctgcgcccgcccgccctcagcctgcctacgtggcc ctgctggcctgtgcagccatcctcttcgtggtgctcatggtggtgtgcaaccggcatagt ttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcagctgtg caggttgggggtgccctggcagccaacccccatagcccatcagtaggcctttggtgccct gtgttctttgtctacatcacctacacgctcctacccatccgcatgcgggcagctgtcttc agtggcctgggcctctccaccctacatatgatcttggcctggcaactcaaccgtggtgat gccttcctctggaagcagcttggtgccaacatgctgctgttcctctgtaccaacgttatt ggcatctgcacacactacccagctgaggtgtctcagcgccaggcctttcaagagactcgt ggctacatccaagcccggctgcacctgcagcatgagaatcggcagcaggagcggctactg ctgtcggtgttgccccagcacgttgccatggagatgaaagaagacatcaacacaaagaaa gaagacatgatgttccacaagatctacatccagaagcatgacaatgtcagcatcctgttt gcagacatcgaaggttttaccagcctggcatcccagtgcaccgcacaggagctggtcatg accctgaatgagctctttgcccggtttgacaagttggctgcggaaaatcactgcctgagg atcaagatcttaggggactgttactactgtgtgtcaggattgcctgaggcccgggcagac catgcccactgctgtgtggagatgggggtggacatgatcgaggccatctcgctggtgcgt gaggtgacaggtgtgaacgtgaacatgcgcgtgggcatccatagcgggcgcgtgcactgc ggtgtccttggcctgcggaaatggcaattcgatgtgtggtccaatgacgtgactctggcc aaccacatggaggcggggggccgggccggccgcatccacatcactcgggccacgctgcag tacctgaatggggactacgaggtggagcctggccatggtggtgagcgcaatgcatacctc aaggagcagcacattgagaccttcctcatcctgggcaccagccagaaacggaaagaggag aaggccatgctggccaagctgcagcggacgcgggccaactctgtggaagggctgatgcca cgctgggtgcctgaccgagccttctcccggaccaaggactccaaggctttccgccagatg ggcattgatgattccagcaaagacaaccggggtgcccaagatgccctgaaccctgaggat gaggtagatgagttcctgggccgtgccattgatgcccgtagcatcgatcagctgcgcaag gaccacgtgcgccggttcctgctcaccttccagagagaggatcttgaaaagaagtactca cagaaagtggatccccgtttcggagcctacgtggcctgtgccctgttggtcttctgcttc atctgcttcatccagcttctcgtcttcccacactcaatgctgatgtttgggatctatgcc gggatcttcctactgctgctgatcactgtgctgacttgcgcggtgtactcctgtggctct ctttgccctaaggccctgcaacgcctgtcgcgcagcattgtacgctcgcgggcacacagc actgcagttggcatcttttcggtcctgcttgtgttcacctccgccatcgccaacatgttc acctgtaaccacacccccatacggacctgtgcagcccggatgctgaatttaacacctgct gacatcaccgcctgccacctgcagcagctcaattattctctgggccttgatgctcccctg tgtgagggcaccgcacccacctgcagcttccctgagtactttgtcgggaacatgctgctg agtctgttggcgagctctgtcttcctgcacatcaatagcatcgggaagttggccatgatc tttgtcctggggctcatctatttggtgctgcttctactgggccccccagccactatcttt gacaactatgatctgctgcttggagtccatggcttggcttcttccaatgagaccttcagt gggctggactgcccagctgcagggagggtggcactcaaatacatgacccccgtgattctg ctggtgtttgcgctggcactgtatctgcatgctcagcaggtggaatcgactgcccgcctg gacttcctctggaaactgcaggcaacaggggagaaggaggagatggaggagctccaggca tacaaccggcgtctgctgcataacatcctgcccaaggatgtggccgcccactttctggcc cgggagcgccggaatgatgagctgtactatcagtcttgtgagtgtgtggctgtcatgttt gcctccattgccaacttctctgagttctacgtggagctggaggcaaacaatgagggtgtc gagtgccttcggctgctcaatgagatcatcgctgactttgatgagatcatcagtgaggag aggttccggcagctggagaagatcaagacgattggtagcacctacatggctgcctctggg ctgaacgccagcacctatgatcaggtgggccgctcccacatcactgccctcgctgactac gctatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaatttccag atgaagattggactgaacatgggccctgtggtggcaggcgtcattggggctcggaagcca cagtatgacatctgggggaatacagtgaatgtctctagccggatggacagcacaggggtt cctgaccgaatccaggtgaccacggacctgtaccaggttctagctgccaagggctaccag ctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctc aatgggggccccagcagttag

Miniopterus natalensis: 107534062 Help Entry 107534062         CDS       T05883                                  Gene name ADCY3 Definition (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism mna  Miniopterus natalensis Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04740   Olfactory transduction mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04962   Vasopressin-regulated water reabsorption mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107534062 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107534062 (ADCY3)    04371 Apelin signaling pathway     107534062 (ADCY3)    04020 Calcium signaling pathway     107534062 (ADCY3)    04072 Phospholipase D signaling pathway     107534062 (ADCY3)    04024 cAMP signaling pathway     107534062 (ADCY3)    04022 cGMP-PKG signaling pathway     107534062 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107534062 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     107534062 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107534062 (ADCY3)    04062 Chemokine signaling pathway     107534062 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     107534062 (ADCY3)    04923 Regulation of lipolysis in adipocytes     107534062 (ADCY3)    04912 GnRH signaling pathway     107534062 (ADCY3)    04913 Ovarian steroidogenesis     107534062 (ADCY3)    04915 Estrogen signaling pathway     107534062 (ADCY3)    04914 Progesterone-mediated oocyte maturation     107534062 (ADCY3)    04921 Oxytocin signaling pathway     107534062 (ADCY3)    04926 Relaxin signaling pathway     107534062 (ADCY3)    04935 Growth hormone synthesis, secretion and action     107534062 (ADCY3)    04918 Thyroid hormone synthesis     107534062 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     107534062 (ADCY3)    04916 Melanogenesis     107534062 (ADCY3)    04925 Aldosterone synthesis and secretion     107534062 (ADCY3)    04927 Cortisol synthesis and secretion     107534062 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107534062 (ADCY3)    04270 Vascular smooth muscle contraction     107534062 (ADCY3)   09154 Digestive system    04970 Salivary secretion     107534062 (ADCY3)    04971 Gastric acid secretion     107534062 (ADCY3)    04972 Pancreatic secretion     107534062 (ADCY3)    04976 Bile secretion     107534062 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107534062 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     107534062 (ADCY3)    04727 GABAergic synapse     107534062 (ADCY3)    04725 Cholinergic synapse     107534062 (ADCY3)    04723 Retrograde endocannabinoid signaling     107534062 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     107534062 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     107534062 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     107534062 (ADCY3)    04213 Longevity regulating pathway - multiple species     107534062 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     107534062 (ADCY3)    04714 Thermogenesis     107534062 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107534062 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     107534062 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107534062 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107534062 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107534062 (ADCY3)    05163 Human cytomegalovirus infection     107534062 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107534062 (ADCY3) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107534062 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  107534062 NCBI-ProteinID:  XP_016064486 LinkDB All DBs Position Unknown AA seq 1145 aa AA seqDB search MPRNQGFSDPEHSAEYSAEYSASLPSDPDRGMGRTHEISVRNWGSCLCLPSFMRLTFVPE SLENLYQTYFRRQRHETLLVLVVFAALFDCYALAMCAVVFSRDKLAPLVVAGVGLVLDIL LYVLCKKGLLPGRVTRKVVPYLLWLLITAQIFSYLSLNFAGLHAAGDTAGWQAFFVFSLF ITLPLGLGPILLLSVASCVVHTLILGVTVAQQQQDRLKGMQLLREILANIFLSLCAITVG IMSYHMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSTCSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLRGEFDVEPGDGGSRCD YLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAPASSKPSSPALIETKEPNGSVHT SGSTSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKERNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCSALVEILIDPWLMTN YVTFVIGELLLLVLTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYSMGPNNGTAGIETEGGCMENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLVTGAVAVINIYAWCPIFDEYDRRRFQEHDFPVVALEKMQILSTTGLNGTDRLPLVPSK YTMTVMIFIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSEKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPATFPNGSSVTLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaatcagggcttctccgatcccgagcactcggctgagtactctgccgagtac tcggccagcctgccctccgaccccgaccgcggcatgggccggacgcacgagatctcggtg cggaactgggggtcctgcctctgcctgcccagcttcatgcggctgaccttcgtgcccgag tccttggagaacctgtaccagacctacttccggaggcagcgccacgagaccctgctggtg ctggtggtcttcgcagcgctcttcgactgctacgcgctggccatgtgcgccgtggtcttc agccgcgacaagctggcgcccctcgtggtggccggggtcgggctggtgttggacatcctc ctctacgtgctctgcaaaaaggggctgctccccgggcgcgtcacccggaaagtggtgccc tacctgctgtggctgctcattacagcccagatcttctcctacctgagcctgaacttcgcg ggcctgcatgcggccggcgacacggcgggctggcaggccttcttcgtcttctccctcttc atcacgctgcccctgggcctcggccccatcctcctcctctccgtggcttcctgtgttgtg cacacgctgattttgggggtcacggtggcccagcagcagcaggacaggctgaaggggatg cagttgctgagagagatcctggccaacatcttcctctccctgtgcgccatcaccgtgggc atcatgtcctaccacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctg tccatcctgcccaagcacgtggccgacgagatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaacgtcagcatc ctcttcgcagacatcgtgggcttcacccagctgtcttctacctgcagcgcccaggagctc gtgaagctgctcaatgagctcttcgcccgcttcgacaagctggcggccaaataccaccag ctgcggattaagatcctgggcgactgctactactgcatctgcggcctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gttcgggagaagacaaagaccggggtggacatgcgtgtgggggtgcacacgggcacggtg ctggggggtgtcctgggccagaagcgctggcagtatgatgtgtggtctactgacgtcact gtggccaacaagatggaggctggcggcatccccgggcgcgtgcacatctcccagagcacc ctggactgcctgagaggagagttcgacgtggagcccggtgacgggggcagccgctgtgat tacctagaggagaagggcatcgaaacctacctcatcattgcgtccaagccggaggtgaag aaaactgccacccaaaatggcctcaacggctcggctctgccaaacggagcgccagcatcc tcaaagcccagctcccctgccctcatcgagaccaaggagcccaatgggagtgtccacacc agtggctccacgtcagaggagcccgaggagcaggatgcccaggctgacaacccctccttc cccaaccctcgccggaggctgcggcttcaggacctggctgaccgagtggtggacgcctct gaggacgagcacgagctcaaccagctgctcaacgaggccctgctcgagcgggagtcggcc caggtagtgaaggagaggaacaccttcctcctgtccatgcggttcatggaccccgagatg gagacccgctactcggtggagaaggaaaagcagagcggggccgccttcagctgctcctgc gtcgtcctgctctgcagcgccttggtggagattctcatcgacccctggctaatgacaaac tacgtgacgtttgtgattggggaacttctgctactggtcctgacgatctgttcactggct gccatctttccccgggcctttcctaagaagctggtggccttctcgacttggattgaccgg acacgctgggccaggaacacctgggccatgttagccatcttcatcctggttatggcaaat gtcgtggacatgctgagctgcctccaatattccatgggacccaacaatggcactgcaggg atagagacggagggtggttgcatggagaaccccaagtattacaactatgtcgctgtgctg tccctcatcgccaccatcatgctggtgcaagtcagccacatggtgaagctcaccctcatg ctgcttgtcacgggtgcggttgccgtcatcaacatctatgcctggtgccccatctttgat gaatatgaccgcagacgtttccaggaacatgactttcctgtggtcgccttggagaagatg cagatcctctccaccactgggctcaatggcactgacaggctgcccttagtgccttctaag tacacgatgacagtgatgatcttcatcatgatgctgagcttctactacttctcccgccac gtggaaaaactggcacggacattgttcttgtggaagattgaggtccatgaccagaaagaa cgtgtctacgagatgcgacgctggaatgaggccttggtcaccaacatgttgcctgagcat gtggcacgccatttcctggggtccaagaagagagatgaggagctgtatagccagtcttat gatgagattggagttatgtttgcctccctgcccaattttgctgacttctacacagaggag agcatcaataatggtggcattgagtgtctgcgcttcctcaacgagatcatctcagatttt gactctcttctagacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagt acctacatggcagcttcaggagtcaccccagatgtcaacaccaacggcttcaccagctcc aacaaggaggaaaagtcagaaaaggagcgctggcaacacctggctgacctggctgacttt gcactagccatgaaggatacccttacgaacatcaacaaccagtccttcaacaacttcatg ctacgcataggcatgaacaaaggaggggtcctggctggagtcattggagcccggaaacca cactacgacatctggggcaacacagtcaatgtagccagcaggatggagtctacaggggtc atgggcaacattcaggtggtagaagaaacacaagccatccttcgagagtacggcttccgc tttgtgaggcgagggcccatctttgtgaaagggaagggggagctgctaacttttttcttg aaggggcgtgataagccagccaccttcccgaatgggtcctctgtgaccctgccccaccag gtagtagacaactcctga

Miniopterus natalensis: 107535777 Help Entry 107535777         CDS       T05883                                  Gene name ADCY9 Definition (RefSeq) adenylate cyclase type 9 isoform X1   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism mna  Miniopterus natalensis Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04961   Endocrine and other factor-regulated calcium reabsorption mna04962   Vasopressin-regulated water reabsorption mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107535777 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107535777 (ADCY9)    04371 Apelin signaling pathway     107535777 (ADCY9)    04020 Calcium signaling pathway     107535777 (ADCY9)    04072 Phospholipase D signaling pathway     107535777 (ADCY9)    04024 cAMP signaling pathway     107535777 (ADCY9)    04022 cGMP-PKG signaling pathway     107535777 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107535777 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     107535777 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107535777 (ADCY9)    04062 Chemokine signaling pathway     107535777 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     107535777 (ADCY9)    04923 Regulation of lipolysis in adipocytes     107535777 (ADCY9)    04912 GnRH signaling pathway     107535777 (ADCY9)    04913 Ovarian steroidogenesis     107535777 (ADCY9)    04915 Estrogen signaling pathway     107535777 (ADCY9)    04914 Progesterone-mediated oocyte maturation     107535777 (ADCY9)    04921 Oxytocin signaling pathway     107535777 (ADCY9)    04926 Relaxin signaling pathway     107535777 (ADCY9)    04935 Growth hormone synthesis, secretion and action     107535777 (ADCY9)    04918 Thyroid hormone synthesis     107535777 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     107535777 (ADCY9)    04916 Melanogenesis     107535777 (ADCY9)    04925 Aldosterone synthesis and secretion     107535777 (ADCY9)    04927 Cortisol synthesis and secretion     107535777 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107535777 (ADCY9)    04270 Vascular smooth muscle contraction     107535777 (ADCY9)   09154 Digestive system    04970 Salivary secretion     107535777 (ADCY9)    04971 Gastric acid secretion     107535777 (ADCY9)    04972 Pancreatic secretion     107535777 (ADCY9)    04976 Bile secretion     107535777 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107535777 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     107535777 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     107535777 (ADCY9)    04727 GABAergic synapse     107535777 (ADCY9)    04725 Cholinergic synapse     107535777 (ADCY9)    04723 Retrograde endocannabinoid signaling     107535777 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107535777 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     107535777 (ADCY9)    04213 Longevity regulating pathway - multiple species     107535777 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     107535777 (ADCY9)    04714 Thermogenesis     107535777 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107535777 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     107535777 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107535777 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107535777 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107535777 (ADCY9)    05163 Human cytomegalovirus infection     107535777 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107535777 (ADCY9) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107535777 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF512 AC_N DUF1053 Motif Other DBs NCBI-GeneID:  107535777 NCBI-ProteinID:  XP_016066833 LinkDB All DBs Position Unknown AA seq 1353 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDNNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS GGVPRRVGAGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMRSKMIFMAAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVFT LLVFSLTLAAQFQVLTPLSGPVDSSNHTPAAKSTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVAYSVLFETFGYHFQDEDCFPSPEAGPRHWELLSRALLHVCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSMKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEHFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGRVTERLGQSVVVDQLKGLKTYLIAGQRAKESHCGCSEALLSGFEVIDGSQVS SGPRGQGTTSPGSVSDLAQTVKTFDNLKTCPSCRITFAPKSEAGAEGGAVQNGCQEEHKN NTKVSGGHNSKAQNGLLSPPQEEKLTNSQTSLCEILQEKGKWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELEQAYRTSYQEEVMKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYGAATTPPPPATLVVFGVALLLEVLSLVVSVR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHITSEFETNIHFTVFMGS AILIAVVHYCNFCQLSSWMRSSLATIVGAGPLLLLYISLCPDSSIVMSHFNAVQNFSSER NPCNSSLLHDSRRPASLVGQEMILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDNGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCQDGSHPQEHLQILFE FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDNGIVPQHQLSISP DIRVQVDGSIGRSPTDEIANLVPSVQNLDKTCLGSENNTQAKDPHLSSKRPWKEPIKAEE RCRFGKAIEKTDCEDMGMEEANELTKLNVSKSV NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcagcaccacagcaccgaggtgagttgtgat tccagcggagacaacaacagcgtgagggtcaaaatcaaccccaagcagctgtcgtccaac agccaccctaaacactgcaagtacagcatctcctccagttgtagcagctctggggactca gggggcgtcccccggagagtgggcgccggaggccgcctgcgcaggcagaagaagctgccc cagctgttcgagagggcctccagtcggtggtgggaccccaagttcgactcggtgaacctg gaggaggcttgcctggagcgctgcttcccgcaaacccagcgccgcttccggtatgcgctt ttctacataggtttcgcctgcctgctctggagcatctattttggggtccacatgagatcc aaaatgattttcatggcagctcctgctctgtgcttcctcgtggtgtgtgtgggctttttc ctgtttaccttcaccaagctgtatgcccgacattatgtgtggacctcgctggttttcacc ctcctggtgttcagcctgactctggctgcccagtttcaggttctgacgcctctctcggga cctgttgacagttccaatcatactcccgcagctaagtccacagacacttgcttatctcaa gtggggagcttttccatgtgcattgaagttctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgtttttgggagtggcatactctgtactttttgagacctttggc tatcatttccaagatgaagactgcttcccctcacctgaagcagggccccggcactgggag ctgctgagccgagccctgctccatgtctgcattcatgccattgggatccacctattcatc atgtcccaggtgagatctagaagcaccttcctcaaggtgggacagtcaattatgcatggg aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccaaga atcattgctgatgacttgatgaaacagggggatgaggagagtgagaattctatgaaaagg catgccacctccagccccaagaacaggaagaaaaagtcttccatacagaaagcccctata gcattccgcccatttaagatgcagcagattgaagaggtcagtattttatttgcagacatc gtaggcttcaccaagatgagtgccaacaagtctgctcatgccctggtaggtctcctcaat gatctgtttggtcgctttgaccggttgtgtgaagagaccaagtgtgagaaaatcagcacc ctgggagactgctactactgtgtggcagggtgccccgaaccccgggctgaccatgcctat tgctgcattgaaatgggcttgggcatgataagagccatcgagcacttctgccaggagaag aaagaaatggtgaacatgcgtgttggggttcacacggggactgttttgtgtggcatcttg ggcatgaggaggtttaaatttgatgtgtggtccaatgacgtgaacctggccaatctcatg gagcagctgggagtggctggcaaggttcacatttctgaggccactgcaaaataccttgat gatcggtacgaaatggaggatgggagagttactgaacgcctcggccagagcgttgttgtt gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcat tgcggctgttcagaggccttgctttctggctttgaggtcattgacggctcacaggtgtcc tcaggtcctaggggacaggggacaacatcaccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccttcatgcagaatcacgtttgctcccaaa tcagaagctggtgcagaagggggcgcagtgcaaaatggctgtcaggaggagcataaaaat aacaccaaggtttctggaggacataattccaaagcacaaaacggactcctgagccctccc caagaggaaaaactcaccaatagccagacctccctgtgtgaaatcttacaggaaaaggga aagtgggcaggtgtcagtttggaccagtctgctctcctcccgctgaggttcaagaacatc cgggagaaaacagacgcccactttgttgatgttatcaaagaagacagcctgatgaaagat tatttttttaagccacccattaatcagttcagcttgaacttcctggatcaggagctagag caagcctacagaaccagctatcaagaagaggttatgaaaaattctccggtgaagactttt gctagtgccaccttcagctccctcctggatgtgtttctgtcaacaacagtgtttctgatt ctctccatcacgtgcttcctgaagtacggggctgccaccacgcctcccccgccagccacc ttggtggtctttggggtagccctgctactggaggtgctgtccctcgtggtctctgtcagg atggtgtttttcctggaggatgtgatggcttgtaccaagcgcctgctggagtggatagcc ggctggctgccacgccatttcattggtgccatcctggtgtcacttcccgctctcgcagtc tattcacacatcacttccgaatttgagacaaacatacatttcaccgtgttcatgggctca gccatcctcatcgctgtggtgcactattgtaacttctgccagctcagctcctggatgcgc tcttccttagccaccatcgtcggggctgggcccctgcttctgctctacatctccctgtgc ccagacagttccatagtaatgtcacattttaatgcagtacagaatttcagttccgagagg aatccatgcaatagttcattgctgcatgacagcaggagaccagccagcctggttggccag gagatgattctcgtcttctttctcttgctcttgttggtctggttcctgaatcgagaattt gaagtcagctaccgcctgcactaccatggggatgtggaggcagaccttcaccgcaccaag atccagagcatgagggaccaagccgactggctgctgaggaacatcatcccctaccatgtg gctgagcagctgaaggtttcccagacctactccaagaatcacgacaatgggggagtcatc tttgccagcattgtcaacttcagtgagttctatgaggagaactacgagggaggcaaggag tgctaccgggtcctcaacgagctgataggggacttcgatgaactcctgagcaagccagac tacagcagcattgagaagattaaaaccattggagccacatacatggccgcatcggggctg aatgccacacagtgccaggatggcagccatccacaggaacacctacagattctgtttgag tttgccaaggagatgatgcgtgtggtggatgacttcaacaacaacatgctgtggttcaac ttcaaactcagagttggcttcaaccacggacccttgacagcaggggtcattggcactacc aagctactgtatgacatctggggagacactgtcaacatcgccagcaggatggacaccaca ggagtggagtgccgcatccaagtgagtgaagaaagctaccgggtcctcagcaagatgggc tacgactttgactacaggggcacagtgaatgtcaagggtaagggtcagatgaagacctac ctttacccaaagtgcacagacaacgggatcgtgccacagcaccagctgtccatttcccca gacatccgagtccaggtggacggcagcatcggacggtctcccacagacgagattgccaac ctggtgccttctgtacagaacttggacaagacatgtctgggttctgagaacaacacgcag gccaaggaccctcacctgtcttctaagagaccctggaaagagcctatcaaagccgaagaa aggtgtcgatttggcaaagccatagagaaaactgactgtgaagatatggggatggaagaa gccaatgaactcaccaagctcaatgtctcaaagagtgtatga

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