Miniopterus natalensis: 107535212
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Entry
107535212 CDS
T05883
Definition
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
KO
K00498
cholesterol monooxygenase (side-chain-cleaving) [EC:
1.14.15.6
]
Organism
mna
Miniopterus natalensis
Pathway
mna00140
Steroid hormone biosynthesis
mna01100
Metabolic pathways
mna04913
Ovarian steroidogenesis
mna04925
Aldosterone synthesis and secretion
mna04927
Cortisol synthesis and secretion
mna04934
Cushing syndrome
Module
mna_M00107
Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
Brite
KEGG Orthology (KO) [BR:
mna00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
107535212
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
107535212
04925 Aldosterone synthesis and secretion
107535212
04927 Cortisol synthesis and secretion
107535212
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
107535212
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
mna00199
]
107535212
Enzymes [BR:
mna01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
107535212
Cytochrome P450 [BR:
mna00199
]
Cytochrome P450, animal type
CYP11 family
107535212
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
107535212
NCBI-ProteinID:
XP_016066070
LinkDB
All DBs
Position
Unknown
AA seq
520 aa
AA seq
DB search
MLVRGLPLRSVLVKGCQPLLNAPQEGLGNPRVPSGEGARISTLMPRPFSEIPSPGENGWL
NLYHFWREKGSQNFHYHQVQNFQKFGPIYREKLGNMESVFIIDPEDVALLFKFEGPTPER
YCIPPWVAYHQHYQRPIGVLFKKSGAWKKDRLALNQEVMTPDAMKNFIPLLDTVSQDFVS
ILHRRIKQQGSGKFSGDISDDLFRFAFESITNVIFGERLGMLEEIVDPEAQRFIDAVYQM
FQTSVPMLMLPPGLFRLFRTKTWRDHVAAWDVIFSKAENYTQNFYLDLRQRRDFNNYPGV
LYRLLGSSKLLFEDVKANITEMLAGGVDTTSMTLQWHLYEMARSLRVQEMLREEVLAARR
QAGEDMSRMLQLVPLLKASIKETLRLHPISVTLQRYLANDLVLRDYMIPAKTLVQVAVYA
MGQDPTFFLHPGKFDPTRWLSENKDLIHFRNLGFGWGIRQCVGRRIAELEMTLFLIHILE
NFRVEIQHLNDVGTTFNLILTPDQPIFFTFRPFIQDLPEA
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgctggtcagggggcttccactgcgttctgtcctggtcaaaggctgccagcccctcttg
aatgccccgcaggaggggctggggaatcccagggtgcccagtggagagggagcccgaatc
tctactctcatgcctcgccctttcagcgagatcccctcccccggtgaaaatggctggcta
aacctataccatttctggagggagaagggctcacagaatttccactatcaccaagtccag
aacttccagaagtttggccccatttacagggagaagcttggcaacatggagtccgttttt
atcattgaccctgaagatgtggcccttctctttaaatttgagggtcccaccccagaacga
tattgcatcccgccctgggttgcctatcaccagcattaccaaagacccatcggagtcctg
ttcaagaagtcaggagcctggaagaaagaccggctggccctgaaccaggaagtgatgact
ccagatgccatgaagaactttatccccctgctggacaccgtgtcccaggacttcgtcagc
atcttgcacaggcgcatcaagcagcagggctccggaaagttctcaggggacatcagtgat
gacctgtttcgctttgccttcgagtccatcaccaacgtcatatttggggagcgcttggga
atgttggaggagatcgtggaccccgaggcccagcggttcattgatgccgtttaccagatg
ttccaaaccagtgtccccatgctcatgcttcccccaggcctgtttcgtctgttcaggacc
aagacatggagggatcatgtggctgcatgggacgtgattttcagtaaagctgaaaactac
acccagaacttttacttggacctgagacagagaagagacttcaataattacccgggcgtc
ctctaccgcctcctgggaagtagcaagttgctcttcgaggatgtcaaggccaacattaca
gagatgttggctgggggtgtggacacgacgtccatgacactgcagtggcacttgtacgag
atggcacgcagcctgagagtgcaggagatgctgcgggaggaggtcctggctgctcggcgc
caggccggggaagacatgagcaggatgctgcagttggtcccgcttctaaaagctagcatc
aaggagacactgagactccaccccatctccgtgaccctgcagagataccttgcaaatgac
ttggttcttcgagattacatgattcctgccaagacattggtgcaggtggccgtctatgcc
atgggacaagatccaaccttcttcctccatccgggcaaatttgaccccacccgatggctg
agtgaaaacaaggacctcatccacttccggaatctaggctttggctgggggattcggcag
tgcgtgggccggcggatcgccgagctcgagatgaccctcttccttatccatattctggag
aatttcagagttgaaatccaacatctcaatgatgtgggcacaacgttcaacctcatcctg
acacccgaccagcccatcttcttcaccttccggccttttatccaggacctgcctgaggca
tga
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